Long-lived radiopharmaceuticals: dispensing from multidose vials.

abstract：OBJECTIVE:The liver is the most frequent metastatic site from colorectal cancer and about 20% of these patients are treated by surgical resection. However, the 5-year disease-free survival (DFS) following resection is only about 25% and 5-year overall survival (OS) about 38%. The aim of the study was to evaluate the ab...

journal_title：Nuclear medicine communications

authors： Grut H,Stern NM,Dueland S,Labori KJ,Dormagen JB,Schulz A

更新日期：2020-09-01 00:00:00

abstract：:In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

journal_title：Nuclear medicine communications

authors： Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

更新日期：1989-11-01 00:00:00

abstract：:The application of a Well-type germanium semiconductor detector creates new possibilities in erythrocyte survival studies. Using 51Cr, the effective dose equivalent in a standard procedure can be reduced from approximately 780 to 2 microSv. The properties of the detector, namely, high efficiency and high energy resolu...

journal_title：Nuclear medicine communications

authors： De Vries RA,Oldenburg SJ,Thelosen T,De Bruin M,Poortman J,Van de Wiel A

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:Collecting positron emission tomography data in three-dimensional (3D) mode may potentially allow reduction of the tracer dose and/or the acquisition time without compromising image quality thereby making the procedure more patient-friendly and cost effective. The objective of our study was to compare VUE Poi...

journal_title：Nuclear medicine communications

authors： Komar G,Teräs M,Seppänen M,Hirvonen J,Vahlberg T,Bergman J,Minn H

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Ewing sarcoma breakpoint region 1 (EWSR1) translocation-negative tumors represent a minor portion of small round cell tumors consistent with Ewing sarcoma morphology. The purpose of this study was to differentiate EWSR1 translocation-positive tumors from EWSR1 translocation-negative tumors using PET-computed...

journal_title：Nuclear medicine communications

authors： Soffer S,Amitai MM,Weizen R,Retter A,Barshack I,Shimon O,Davidson T,Klang E

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Clinical studies in women using technetium-99m (Tc)-Bombesin have shown successful radionuclide imaging of breast tumours overexpressing gastrin-releasing peptide receptors (GRPRs). Recent studies have demonstrated that most breast tumours overexpress folate receptors (FRα). AIM:The aim of this work was to ...

journal_title：Nuclear medicine communications

authors： Aranda-Lara L,Ferro-Flores G,Ramírez Fde M,Ocampo-García B,Santos-Cuevas C,Díaz-Nieto L,Isaac-Olivé K

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIM:Researchers find that monitoring the differentiation of implanted cells in vivo is difficult. This study was designed to show that it is possible to track the efficacy of transplanted human retinal pigment epithelial cells (RPE cells) in a rat model of Parkinson's disease by using positron emission t...

journal_title：Nuclear medicine communications

authors： Wang R,Zhang J,Guo Z,Shen L,Shang A,Chen Y,Yao S,He T,Yin D,Tian J

更新日期：2008-05-01 00:00:00

abstract：:First-pass radionuclide angiography, for the evaluation of ventricular function during peak physiological stress, requires the use of a low-energy point source for correction of motion artifacts. A design for the construction of a refillable 125I point source is presented. ...

journal_title：Nuclear medicine communications

authors： Hirsch JI,Fuhs BE,Tatum JL,Tatum TG

更新日期：1992-01-01 00:00:00

abstract：:Early diagnosis in Alzheimer's disease (AD) is important for the administration of new treatments. The purpose of this study was to differentiate mildly/moderately demented AD patients from normal controls by means of activational brain SPECT, and to investigate the correlation between regional cerebral blood flow and...

journal_title：Nuclear medicine communications

authors： Sayit E,Yener G,Capa G,Ertay T,Keskin B,Fadiloglu S,Durak H

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Positron emission tomography (PET) imaging using [18F]fluorodeoxyglucose (18F-FDG) is recognized to have a major role in oncological imaging. Over recent years there has been a steady increase in the use of gamma camera PET (GCPET) systems as these are less expensive than dedicated PET scanners and facilitat...

journal_title：Nuclear medicine communications

authors： Marshall C,Mustafa S,Wheatley DC,Eremin JE,El-Sheemy M,Jibril JA,Eremin O,Griffiths PA

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:The current study was performed to evaluate the impact of Tc-EDDA-tricine-HYNIC-Tyr-octreotate in the differentiation of active from inactive pulmonary tuberculosis lesions. PATIENTS AND METHODS:Ten consecutive patients (six male and four female, age range 24-83 years) with proven pulmonary tuberculosis (wit...

journal_title：Nuclear medicine communications

authors： Ahmadihosseini H,Abedi J,Ghodsi Rad MA,Zakavi SR,Knoll P,Mirzaei S,Sadeghi R

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare the sensitivity of single-photon emission computed tomography/computed tomography (SPECT/CT) using 99mTc-sestamibi (MIBI) with that of PET/CT using 11C-methionine (MET) for localization of parathyroid adenomas/hyperplasia in primary hyperparathyroidism. MATERIALS AND ...

journal_title：Nuclear medicine communications

authors： Hayakawa N,Nakamoto Y,Kurihara K,Yasoda A,Kanamoto N,Miura M,Inagaki N,Togashi K

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:Differential renal function (DRF) calculation with 99mTc-diethylenetriamine-pentaacetic acid (DTPA) or mercaptoacetyltriglycine (MAG3) is gaining clinical importance in the evaluation of patients with ureteropelvic junction obstruction with hydronephrosis (HN). Although many decisions regarding surgery are b...

journal_title：Nuclear medicine communications

authors： Caglar M,Gedik GK,Karabulut E

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To assess standardized uptake value (SUV) measurement uncertainty (MU) of lung cancer lesions with uptake greater than mediastinum but less than or equal to the liver and that of the mediastinum blood pool, and to compare lesion SUV with mediastinum SUV by assessing MU of their ratio. PATIENTS AND METHODS:Dy...

journal_title：Nuclear medicine communications

authors： Laffon E,Milpied N,Marthan R

更新日期：2017-06-01 00:00:00

abstract：:In order to compare visual interpretation of inflammation detected by leukocyte scintigraphy with that of different computer-aided quantification methods, 34 patients (25 with ulcerative colitis and 9 with endoscopically verified non-inflamed colonic mucosa), were investigated using 99Tcm-hexamethylpropyleneamine oxim...

journal_title：Nuclear medicine communications

authors： Almer S,Peters AM,Ekberg S,Franzén L,Granerus G,Ström M

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...

journal_title：Nuclear medicine communications

authors： Zhang Y,He J,Liu G,Venderheyden JL,Gupta S,Rusckowski M,Hnatowich DJ

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the evolution of patients with internal mammary chain (IMC) drainage whether the IMC-sentinel lymph node (IMC-SLN) was biopsied or not, as well as to determine the clinical implications of the biopsy of the IMC-SLN (IMC-SLNB) in patients with breast cancer and IMC drainag...

journal_title：Nuclear medicine communications

authors： Domènech-Vilardell A,Bajén MT,Benítez AM,Ricart Y,Mora J,Rodríguez-Bel L,García-Tejedor A,Climent J,López-Ojeda A,Urruticoechea A,Martín-Comín J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the cerebral amyloid distribution in patients with mild cognitive impairment (MCI), assessed by carbon-11-Pittsburgh compound B (C-PIB) PET/CT, after 5 years of follow-up. PATIENTS AND METHODS:Ten amnestic MCI (A-MCI) and four nonamnestic (NA-MCI) patients were studied b...

journal_title：Nuclear medicine communications

authors： Jiménez-Bonilla JF,Quirce R,De Arcocha-Torres M,Martínez-Rodríguez I,Martínez-Amador N,Sánchez-Salmón A,De la Fuente-Gómez F,Rodríguez E,Sánchez-Juan P,Banzo I

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Assessing the relative function of each of the three kidneys using nuclear scintigraphy with standard planar imaging in patients having undergone kidney transplant is problematic because of the different photon-attenuation factors associated with native versus transplanted kidneys. To address this, we applied...

journal_title：Nuclear medicine communications

authors： Palmer MR,Donohoe KJ,Francis JM,A Mandelbrot D

更新日期：2011-08-01 00:00:00

abstract：:A technique is described for the quantification of the three-dimensional distribution of 131I radiopharmaceuticals using single photon emission computed tomography (SPECT). A theoretical discussion of the problems of scatter and septal penetration in 131I SPECT is presented. The correction of these effects using the g...

journal_title：Nuclear medicine communications

authors： Fleming JS,Alaamer AA,Perring S

更新日期：1993-06-01 00:00:00

abstract：:The physical considerations of using dual isotope brain SPECT imaging to monitor blood flow changes during cognitive activation studies were investigated. These factors included field uniformity, spatial resolution and crosstalk. Serial dual isotope single photon emission computed tomographic (SPECT) studies of a test...

journal_title：Nuclear medicine communications

authors： Madsen MT,O'Leary DS,Andreasen NC,Kirchner PT

更新日期：1993-05-01 00:00:00

abstract：:The combined use of 123I-BMIPP and 99Tcm-MIBI SPET imaging has been proposed as an alternative to PET for the non-invasive detection of jeopardized myocardium after a myocardial infarction, a mismatch accurately indicating jeopardized but still viable tissue. In this paper, a new quantitative approach is described, ex...

journal_title：Nuclear medicine communications

authors： Hambÿe AS,Dobbeleir A,Franken PR

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:Computed tomography (CT) automatic exposure control (AEC) systems are now used in all modern PET-CT scanners. A collaborative study was undertaken to compare AEC techniques of the three major PET-CT manufacturers for fluorine-18 fluorodeoxyglucose half-body oncology imaging. MATERIALS AND METHODS:An audit o...

journal_title：Nuclear medicine communications

authors： Iball GR,Tout D

更新日期：2014-04-01 00:00:00

abstract：:Should one correct for extrathyroidal neck radioactivity ('neck background') when interpreting perchlorate discharge test results? A new background correction method was developed using a linear probe. 123I produces photon peaks at two energy levels: 159 keV (gamma-rays) and 28 keV (X-rays), with an attenuation of 15 ...

journal_title：Nuclear medicine communications

authors： Arntzenius AB,van der Heide D,Meinders AE

更新日期：1992-11-01 00:00:00

abstract：:Radiolabeled immunotherapy (RIT) is becoming a significant step forward in the treatment management of non-Hodgkin's lymphoma (NHL). In this state-of-the-art review article, general details, practical and health economic aspects, and next steps of RIT in NHL are reviewed from the existing literature and latest abstrac...

journal_title：Nuclear medicine communications

authors： Otte A,van de Wiele C,Dierckx RA

更新日期：2009-01-01 00:00:00

abstract：AIM:99mTc-HL91 is a new hypoxia agent and can identify acutely ischaemic viable myocardium in a canine model using a standard gamma camera. The purpose of the study was to determine whether this tracer could be used to detect regional ischaemia in chronic ischaemic myocardium in a swine model. METHOD:Using a porcine m...

journal_title：Nuclear medicine communications

authors： Wu YW,Lee CM,Huang YH,Chou NK,Yen RF,Tzen KY,Huang PJ

更新日期：2005-12-01 00:00:00

abstract：:Cerebral blood flow (CBF) can be quantified non-invasively using the brain perfusion index (BPI) determined from radionuclide angiographic data generated with 99mTc-hexamethylpropylene amine oxime (99mTc-HMPAO). When measuring the BPI, manual drawing of regions of interest (ROIs) (manual ROI method) for the extraction...

journal_title：Nuclear medicine communications

authors： Murase K,Nagayoshi M,Uenishi Y,Kawamata M,Yamazaki Y,Takasawa M,Oku N,Hatazawa J

更新日期：2004-03-01 00:00:00

abstract：AIMS:The aims of this study were to improve the quantification of lower extremity lymphoscintigraphy, determine its value and lower limit of normal, and determine whether intermediate postinjection time imaging is necessary. PATIENTS AND METHODS:This was a study of 102 consecutive patients undergoing routine lower ext...

journal_title：Nuclear medicine communications

authors： Keramida G,Winterman N,Wroe E,Aplin M,Peters AM

更新日期：2017-03-01 00:00:00

abstract：:The biodistribution of two stereoisomeric 99Tcm complexes derived from diastereomeric dimercaptosuccinic acids (DMSA), 99Tcm-dl-DMSA and 99Tcm-meso-DMSA, was examined in sarcoma 180 tumour-bearing mice. The biodistribution pattern of meso-complex was not significantly different from 99Tc(V)m-DMSA, a new tumour imaging...

journal_title：Nuclear medicine communications

authors： Awh OD,Kim JR,Shim SC

更新日期：1989-06-01 00:00:00

abstract：PURPOSE:Respiratory gated perfusion single photon emission computed tomography (SPECT) was applied to reduce respiratory lung motion effects and to reliably assess perfusion impairment in various lung diseases. METHODS:After injection of 259 MBq of 99mTc macroaggretated albumin (99mTc-MAA), gating was performed using ...

journal_title：Nuclear medicine communications

authors： Suga K,Kawakami Y,Zaki M,Yamashita T,Matsumoto T,Matsunaga N

更新日期：2004-02-01 00:00:00