Abstract:
:A method of deconvolution analysis involving the use of the z-transform has been developed. When compared to the matrix method, it is shown, under certain circumstances, to be identical. In order to study the validity of the method, simple mathematical models have been constructed. The curves obtained with the computed method closely fitted those obtained by mathematical analysis. The z-transform algorithm was applied to clinical data in order to demonstrate its validity for the deconvolution of renograms. The advantages of the method over the matrix method are discussed.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Bererhi Hsubject
Has Abstractpub_date
1995-03-01 00:00:00pages
161-7issue
3eissn
0143-3636issn
1473-5628journal_volume
16pub_type
杂志文章abstract::Quantification of the number of receptors per cell (NRPC) is important when assessing whether a tumor surface biomarker is suitable for medical imaging. One common method for NPRC quantification is to use a binding saturation assay, which is time consuming and requires large amounts of reagents. The aim of this study ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283483e1c
更新日期:2011-09-01 00:00:00
abstract::Optical luciferase gene imaging is emerging as a method to monitor gene expression in small animals. However, there is concern over how regional availability of exogenously administered substrate may affect photon emission. We thus synthesized [125I]iodo-D-luciferin, which demonstrated substrate characteristics for fi...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200309000-00009
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the diagnostic accuracy of PET/computed tomography (CT) in detecting marrow infiltration in indolent non-Hodgkin lymphoma (NHL) with histopathological correlation. METHODS:All treatment-naive newly diagnosed indolent NHL with staging PET/CT were retrospectively evaluated for marrow infiltration a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000361
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the potential of (99m)Tc-pamidronate ((99m)Tc-APD) against (99m)Tc-medronate ((99m)Tc-MDP) as a new bone-seeking agent using intact bone and fractured femur in a rat model. METHODS:(99m)Tc-APD was prepared by the stannous reduction method. Scintigraphic images were obtained at 2 h and 24 h after ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328013eb74
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to evaluate the role of F-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (CT) in the early postoperative staging of breast cancer and to document (18)F-FDG PET/CT-based stage alterations and any subsequent impact on management. MATERIALS AND METHODS:Between January 2009 and ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328360d8ec
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:To compare the accuracy of various equations for estimating glomerular filtration rate. METHODS:Chronic kidney disease was classified by Tc-DTPA scintigraphy (reference glomerular filtration rate), estimating glomerular filtration rate was estimated using various formulas. The similarity to reference glomer...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001141
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:To determine whether any patient or hepatic tumor characteristics are predictive of hepatopulmonary shunt fraction when performed before radioembolization. MATERIALS AND METHODS:A retrospective review was performed on 190 patients who underwent preradioembolization hepatic arteriography with calculation of h...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000528
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:Exclusive use of the half-time of clearance of a filtration marker in the bolus injection, single compartment technique for measuring glomerular filtration rate (GFR) is a convenient approach that gives GFR (GFR(SO)) already scaled for extracellular fluid volume (ECV). It has been criticized as less accurate th...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3281ec51b5
更新日期:2007-09-01 00:00:00
abstract::INTRODUTION:: [Ga]Ga-prostate specific membrane antigen (PSMA)-11 showed a clear gain in sensitivity for lesion detection in the biological recurrence of prostate cancer as compared to the standard [F]fluorocholine radiopharmaceutical. To meet the strong demand for [Ga]Ga-PSMA-11, we aimed to optimize an automated rad...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001233
更新日期:2020-06-18 00:00:00
abstract:BACKGROUND AND PURPOSE:It is known that fluorine-18 fluorodeoxyglucose PET/computed tomography (CT) segmentation algorithms have an impact on the metabolic tumor volume (MTV). This leads to some uncertainties in PET/CT guidance of tumor radiotherapy. The aim of this study was to investigate the effect of segmentation a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000641
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:Radioiodine ablation of thyroid tissue remains the cornerstone of treatment for patients with differentiated thyroid carcinoma after thyroidectomy. Selecting an optimal dose of radioiodine for successful ablation is a continuous challenge in these patients. METHODS:We compared the treatment response of 341 ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,随机对照试验
doi:10.1097/MNM.0b013e32834e306a
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:The P2X7 receptor (P2X7R) is a key regulatory element in the neuroinflammatory cascade that provides a promising target for imaging neuroinflammation. GSK1482160, a P2X7R modulator with nanomolar binding affinity and high selectivity, has been successfully radiolabeled and utilized for imaging P2X7 levels in ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000660
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine the fraction of administered activity that was excreted and retained by a small cohort of patients who each received treatment with radium-223 dichloride (Ra). Ra is an α-emitting radionuclide that has been approved for use in the treatment of bone metastases that are sec...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000783
更新日期:2018-02-01 00:00:00
abstract::Positron emission tomography (PET) using F-18 fluoro-3'-deoxy-3-L-fluorothymidine (FLT) offers noninvasive assessment of cell proliferation in vivo. The most important application refers to the evaluation of tumour proliferative activity, representing a key feature of malignancy. Most data to date suggest that FLT is ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/MNM.0b013e32832ee93b
更新日期:2009-12-01 00:00:00
abstract::Conventional nuclear medicine methods for measuring glomerular filtration rate, GFR, are invalidated if the initial injection of radiopharmaceutical is tissued. An analytical method proposed by Veall and Gibbs in 1982 overcomes this difficulty but does require multiple blood samples. This paper investigates whether it...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198611000-00003
更新日期:1986-11-01 00:00:00
abstract::Renal artery stenosis is an important and potentially curable cause of hypertension. Captopril renography is now recognized to have a high sensitivity and specificity in its diagnosis. Ultimately, however, the result is of little benefit if it does not lead to a change in patient management. To assess how patient mana...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199707000-00006
更新日期:1997-07-01 00:00:00
abstract:INTRODUCTION:In pediatric patients with abdominal Burkitt's lymphoma, the involvement of the gastrointestinal tract and abdominal lymph nodes are the main presenting feature of the disease. Chemotherapy is the main treatment modality and could be preceded by surgical excision of the abdominal masses. To achieve cure or...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328334fc14
更新日期:2010-03-01 00:00:00
abstract::Medullary thyroid carcinoma (MTC) is a neuroendocrine tumour characterized by the production and secretion of calcitonin. MTC tumours may express functional somatostatin receptors (hSSTR). A significant proportion of hSSTR receptor-positive MTC tumours, including metastatic disease, may be visualized in vivo through 1...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199609000-00013
更新日期:1996-09-01 00:00:00
abstract:AIM:To test the applicability of Tc-dextran joint scintigraphy in the assessment of disease activity in patients with rheumatoid arthritis (RA), and to compare it with the clinical disease activity scores and laboratory parameters. METHODS:Twenty-seven patients with RA were investigated using Tc-dextran joint scintigr...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/01.mnm.0000126632.32413.2e
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the diagnostic value of 2-(fluorine-18)-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT in comparison with MRI for the detection of recurrent ovarian cancer. METHODS:Forty-seven patients with suspected ovarian cancer recurrence after total ablative or cytoreductive surgery, ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32834fc5bf
更新日期:2012-05-01 00:00:00
abstract:AIM:This study aims to assess the diagnostic role of F-FDG PET/computed tomography in primary staging and restaging of testicular cancer in comparison with contrast-enhanced diagnostic thoracic-abdominopelvic computed tomography. MATERIAL AND METHOD:Thirty-two consecutive male patients with testicular carcinoma (media...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001093
更新日期:2019-12-01 00:00:00
abstract::The combination of a diagnosis of malignancy and hospitalization, isolation and radioactivity of a radionuclide therapy may have an important effect on the psychological equilibrium of patients and may hamper compliance and acceptability. We performed a psychiatric evaluation in order to study psycho-pathological mani...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/01.mnm.0000084586.29433.83
更新日期:2003-08-01 00:00:00
abstract::Altogether, 147 scintiscans, completed 48-72 h after 74 MBq 131I, were compared with scintiscans obtained on average 7.8 days after therapeutic doses of 131I. The therapeutic doses ranged from 1100 to just over 7400 MBq. The reasons for the investigation were to determine (1) if the diagnostic dose interfered with upt...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199706000-00002
更新日期:1997-06-01 00:00:00
abstract::Fifty-six patients with hypertrophic cardiomyopathy who had echocardiography and cardiac catheterization were studied. Eleven (18%) of 56 patients had right ventricular (RV) thallium-201 visualization at resting scan. RV thallium-201 visualization was observed in the apex or lower half of the RV free wall, which was q...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:In studies of the distribution of lung function, the image quality of lung single photon emission computed tomography (SPECT) is important and one factor influencing it is the reconstruction algorithm. AIM:To systematically evaluate ordered subsets expectation maximization (OSEM) and compare it with filtere...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f1acac
更新日期:2007-12-01 00:00:00
abstract:AIM:To develop a strategy for checking the reliability of slope intercept measurement of glomerular filtration rate (GFR). METHODS:Six blood samples, obtained bilaterally 20-240 min after the injection of Cr-ethylenediaminetetraacetic acid (EDTA) and iohexol into opposite arms, were assayed for indicator injected cont...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328310b378
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:This work aims to assess whether the biochemical response of radium-223-dichloride treatment can be predicted based on the pretherapy bone scan, and consequently if bone scan index (BSI) and maximum lesion intensity have a place as alternatives or as complements to extent of bone disease (EOBD) scoring in pr...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001005
更新日期:2019-06-01 00:00:00
abstract::Sodium iodide (131I) capsules are widely used for both diagnosis and therapy. The radiochemical purity of both diagnostic and therapeutic capsules in use in Australia was studied by gel chromatography, high voltage electrophoresis and paper chromatography. It was found that in two of the three bands of therapeutic cap...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198611000-00007
更新日期:1986-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200411000-00008
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:Extraskeletal findings detected on whole-body low-dose unenhanced computed tomography (CT) as a part of F-NaF PET/CT scans can be numerous and present challenges for further management. Here, we investigate the frequency and clinical significance of extraskeletal findings among 130 consecutive patients undergoi...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000531
更新日期:2016-09-01 00:00:00