Bone scan index as metastatic bone disease quantifier and predictor of radium-223-dichloride biochemical response.

abstract：OBJECTIVE:Easy large-scale production, easy availability, cost-effectiveness, long half-life, and favorable radiation characteristics have made lutetium-177 (Lu) a preferred radionuclide for use in therapy. Lutetium-177-labeled stannous (Lu-Sn) colloid particles were formulated for application in radiosynovectomy, foll...

journal_title：Nuclear medicine communications

authors： Arora G,Singh M,Jha P,Tripathy S,Bal C,Mukherjee A,Shamim SA

更新日期：2017-07-01 00:00:00

abstract：:Technetium-99m-galactosyl human serum albumin (99mTc-GSA) is a radiopharmaceutical that binds to asialoglycoprotein receptors in the hepatocyte membrane; the level of 99mTc-GSA accumulation in the liver correlates well with the parameters of hepatic function tests. We hypothesized that the early blood kinetics of 99mT...

journal_title：Nuclear medicine communications

authors： Sugai Y,Komatani A,Hosoya T,Takahashi K

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Vectorized internal radiation therapy using lipiodol-labelled with iodine-131 (131 I-lipiodol) is an effective treatment for inoperable hepatocellular carcinomas. However, few dosimetric data are available based on this approach. We have developed a dosimetric protocol based on scintiscan imaging and that is ...

journal_title：Nuclear medicine communications

authors： Becker S,Laffont S,Vitry F,Rolland Y,Lecloirec J,Boucher E,Raoul JL,Herry JY,Bourguet P,Garin E

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:Radionuclide therapies, including treatment of neuroendocrine tumors with lutetium-177 (Lu-177) octreotate, often involve hospital admission to minimize radiation exposure to the public. Overnight admission due to Lu-177 octreotate therapy incurs additional cost for the hospital and is an inconvenience for t...

journal_title：Nuclear medicine communications

authors： Olmstead C,Cruz K,Stodilka R,Zabel P,Wolfson R

更新日期：2015-02-01 00:00:00

abstract：INTRODUCTION:An image-processing algorithm (AUTOROI) has been developed to totally automatically (or with manual assistance) detect whole-kidney contours and generate renal regions of interest (ROI) for the extraction of the quantitative measurements used in the interpretation of Tc-mercaptoacetyltriglycine (Tc-MAG3) r...

journal_title：Nuclear medicine communications

authors： Garcia EV,Folks R,Pak S,Taylor A

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Simulated data from the recent Institute of Physics and Engineering in Medicine audit of quantitative cerebral perfusion were used to optimize the parameters of eigenimage analysis, a method for computer-aided detection. METHODS:Twenty normal images provided by the audit were registered to the International ...

journal_title：Nuclear medicine communications

authors： Houston AS,Fleming JS,Ward T,Hoffmann SM

更新日期：2009-09-01 00:00:00

abstract：:The impact of recent advances in the chemical and genetic engineering manipulations of antibodies on radioimmunotargeting is reviewed both in relation to radioimmunoscintigraphy and radioimmunotherapy. The resulting trends are: (1) the linking of parts of the mouse/rat and human antibody molecule; (2) the creation of ...

journal_title：Nuclear medicine communications

authors： Hazra DK,Britton KE,Lahiri VL,Gupta AK,Khanna P,Saran S

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:The herpes simplex virus thymidine kinase (HSVtk) gene has frequently been applied as a reporter gene for monitoring transgene expression in animal models. In clinical gene therapy protocols, however, extremely low expression levels of the transferred gene are generally observed. Consequently, sensitive and s...

journal_title：Nuclear medicine communications

authors： Buursma AR,Rutgers V,Hospers GA,Mulder NH,Vaalburg W,de Vries EF

更新日期：2006-01-01 00:00:00

abstract：:PET holds potential to provide additional information about tumour metabolic processes, which could aid brain tumour differential diagnosis, grading, molecular subtyping and/or the distinction of therapy effects from disease recurrence. This review discusses PET techniques currently in use for untreated and treated gl...

journal_title：Nuclear medicine communications

authors： Mansoor NM,Thust S,Militano V,Fraioli F

更新日期：2018-12-01 00:00:00

abstract：:Thirty patients with aortic valve incompetence and 21 control subjects were examined by M-mode echocardiography at rest and radionuclide ventriculography during submaximal handgrip exercise. The patients had greater left ventricular dimensions and end-systolic wall stress values but peak systolic wall stress values di...

journal_title：Nuclear medicine communications

authors： Groundstroem K,Huikuri H,Korhonen U,Ikäheimo M,Heikkilä J,Torniainen P,Linnaluoto M,Takkunen J

更新日期：1990-04-01 00:00:00

abstract：:Thallium-201 (201Tl) stress-redistribution/reinjection imaging provides a reliable diagnostic approach in patients evaluated for myocardial ischaemia. Immediate reinjection of 201Tl after completing the stress images followed by imaging 1 h later shortens the investigation time to 2.5 h and may provide a novel approac...

journal_title：Nuclear medicine communications

authors： van Eck-Smit BL,van der Wall EE,Zwinderman AH,Pauwels EK

更新日期：1995-10-01 00:00:00

abstract：:The aim of this prospective study was to assess the efficacy of using whole-kidney, mean parenchymal and pelvic transit times to evaluate renal function following treatment with extracorporeal shock wave lithotripsy (ESWL). Fifteen patients were evaluated 24-48 h before and after ESWL therapy using 99Tcm-DTPA renal sc...

journal_title：Nuclear medicine communications

authors： Ilgin N,Iftehar SA,Vural G,Bozkirli I,Gokcora N

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:Human serum albumin (HSA), which has 58 Lys residues, one Cys residue, and indocyanine green (ICG) adsorption sites, can be used as a multifunctional platform for the development of hybrid imaging probes. In this study, we prepared 64Cu-labeled mannose-conjugated HSA with and without ICG ([64Cu]1-ICG and [64C...

journal_title：Nuclear medicine communications

authors： Kang CM,An GI,Choe YS

更新日期：2015-10-01 00:00:00

abstract：:The aim of this study was to develop a quantitative method to assess viable tumour based on post-operative 201Tl single photon emission tomography (SPET). We studied 15 patients with histologically defined highly malignant gliomas in the post-operative phase before initiation of adjuvant treatment. A 201Tl index was c...

journal_title：Nuclear medicine communications

authors： Källén K,Geijer B,Andersson AM,Holtås S,Ryding E,Rosén I

更新日期：1999-09-01 00:00:00

abstract：:A significant number of patients with primary hyperparathyroidism have negative preoperative 201Tl/99Tcm subtraction localization scans. In this study an attempt was made to improve scan localization by creating a period of relative hypocalcaemia and increased parathyroid hormone (PTH) secretion before scanning. Six p...

journal_title：Nuclear medicine communications

authors： Gallacher SJ,Fraser WD,Logue FC,Boyle IT,Gray HW,McKillop JH

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:Many studies have attempted to assess the significance of the use of the β(-)particle emitter praseodymium-142 ((142)Pr) in cancer treatment. As praseodymium oxide (Pr(2)O(3)) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable ...

journal_title：Nuclear medicine communications

authors： Bakht MK,Sadeghi M,Ahmadi SJ,Sadjadi SS,Tenreiro C

更新日期：2013-01-01 00:00:00

abstract：:The aims of this study were to establish the percentage of metastatic renal cell carcinoma (RCC) lesions detected by radioimmunoscintigraphy (RIS) with the chimeric monoclonal antibody 131I-cG250 versus positron emission tomography (PET) with 18F-labelled deoxyglucose ([18F]FDG), and to evaluate the use of these radio...

journal_title：Nuclear medicine communications

authors： Brouwers AH,Dorr U,Lang O,Boerman OC,Oyen WJ,Steffens MG,Oosterwijk E,Mergenthaler HG,Bihl H,Corstens FH

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:Respiratory complications are common after arthroplasty, with pulmonary thromboembolic disease (PTE) and fat emboli being the most serious. A scintigraphic study was designed to assess the occurrence of both diseases. A prospective tomographic study of perfusion was performed within 24 h of arthroplasty. D...

journal_title：Nuclear medicine communications

authors： Bruce W,Van der Wall H,Peters M,Liaw Y,Morgan L,Storey G

更新日期：2001-11-01 00:00:00

abstract：AIM:About 90% of insulinomas are benign and 5-15% are malignant. Benign insulinomas express the glucagon-like peptide-1 receptor (GLP-1R, which recognizes exendin-4 and low levels of the somatostatin receptor (SSTR, which recognizes octreotide), whereas malignant insulinomas overexpress SSTR and low levels of GLP-1R. R...

journal_title：Nuclear medicine communications

authors： Ocampo-García BE,Santos-Cuevas CL,Luna-Gutiérrez MA,Ignacio-Alvarez E,Pedraza-López M,Manzano-Mayoral C

更新日期：2017-11-01 00:00:00

abstract：:Foot problems are common causes of disability in diabetic patients with as many as 25% expected to develop severe foot or leg problems during their lifetimes. Although skin ulceration is the most frequent problem, bones may also be involved in two different clinical conditions: osteomyelitis and Charcot osteoarthropat...

journal_title：Nuclear medicine communications

authors： Giurato L,Uccioli L

更新日期：2006-09-01 00:00:00

abstract：:LL1, a monoclonal antibody (MAb) to HLA Class-II-like antigen (li determinant) on the surface of B-lymphocytes, monocytes and histiocytes, was evaluated as an agent for bone marrow imaging. Six patients with diverse diseases (non-Hodgkin's lymphoma, n = 2; multiple myeloma, n = 1; polycythaemia vera, n = 1; lung cance...

journal_title：Nuclear medicine communications

authors： Juweid M,Dunn RM,Sharkey RM,Rubin AD,Hansen HJ,Goldenberg DM

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:We estimated the absorbed doses for (111)In-DTPA-D-Phe(1)-octreotide and (90)Y-DOTA-D-Phe(1)-Tyr(3)-octreotide in the same patients in order to compare the potential effectiveness (tumour dose) and safety (kidney and red marrow dose) of these drugs for peptide-targeted radiotherapy of somatostatin receptor po...

journal_title：Nuclear medicine communications

authors： Barone R,Walrand S,Konijnenberg M,Valkema R,Kvols LK,Krenning EP,Pauwels S,Jamar F

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to analyze the uptake of rubidium in malignant tumors. PARTICIPANTS AND METHODS:Sixteen malignant lesions were included. Two radiologists compared each lesion to four references (subcutaneous fat, lung, mediastinal blood pool, and liver) at rest and stress and scored as 1-4. M...

journal_title：Nuclear medicine communications

authors： Khandani AH,Commander CW,Desai H,Oldan JD,Wong TZ,Benefield T,Ivanovic M

更新日期：2019-05-01 00:00:00

abstract：:Ion-exchange resin beads, implanted into connective tissue, were used as the vehicle for the delivery of radiolabelled cations to determine the local distribution of lead, silver and cadmium in loose connective tissue. The system was devoid of systemic toxicity, permitted a predictable release, enabled location of rel...

journal_title：Nuclear medicine communications

authors： Ellender G,Ham KN

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:Nuclear medicine procedures are often performed in close-time proximity to bone densitometry studies. The purpose of this study was to determine the effects of Tc-hexakis-2-methoxyisobutyl isonitrile (MIBI) and Tc-methylene diphosphonate (MDP) on the accuracy of bone mineral density (BMD) measurements perform...

journal_title：Nuclear medicine communications

authors： Gumuser G,Parlak Y,Topal G,Aras F,Ruksen E,Sayit E

更新日期：2009-06-01 00:00:00

abstract：:An increased uptake of bone-seeking radiopharmaceuticals into malignant bone lesions could further improve the diagnostic accuracy of routine bone scanning. The tracers used in clinical routine for bone scanning are methylene-diphosphonate (MDP), dicarboxypropane-diphosphonate (DPD) and ethylenediaminetetramethylene-p...

journal_title：Nuclear medicine communications

authors： Fueger BJ,Mitterhauser M,Wadsak W,Ofluoglu S,Traub T,Karanikas G,Dudczak R,Pirich C

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess the association between the burden of metastatic bone disease measured on F-NaF PET/computed tomography (CT) studies and the overall survival (OS) of patients with medullary thyroid cancer (MTC). METHODS:We retrospectively analyzed 31 patients with MTC who performed 18F-NaF P...

journal_title：Nuclear medicine communications

authors： Ueda CE,Duarte PS,de Castroneves LA,Flávio J,Marin G,Sado HN,Sapienza MT,Hoff AO,Buchpiguel CA

更新日期：2020-05-01 00:00:00

abstract：:Radioimmunoscintigraphy (RIS) and radioimmunoguided surgery (RIGS) were assessed for their usefulness in patients with colorectal carcinoma. Twenty-nine patients (18 primary tumours, 10 with a suspicion of recurrence and one colonic diverticulitis) were studied. Radioimmunoscintigraphy was performed 48 and 72 h after ...

journal_title：Nuclear medicine communications

authors： Muxi A,Pons F,Vidal-Sicart S,Setoain FJ,Herranz R,Novell F,Fernandez RM,Trias M,Setoain J

更新日期：1999-02-01 00:00:00

abstract：:Neuroendocrine tumors (NETs) are rare in childhood. Neuroblastoma is the most common pediatric extracranial solid tumor, occurring >90% in children younger than 5 years of age. Pheochromocytoma and paraganglioma are rare NETs, causing hypertension in 0.5-2% of hypertensive children. Gastroenteropancreatic NETs can occ...

journal_title：Nuclear medicine communications

authors： Haddad T,Fard-Esfahani A,Vali R

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Lymphoid hyperplasia is not uncommon in the midline roof of the nasopharynx. Most nasopharyngeal carcinoma patients present with primary tumors in the midline of the nasopharynx. The aim of this study was to evaluate the efficacy of 2-[fluorine-18] fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/computed tomography (C...

journal_title：Nuclear medicine communications

authors： Chen YK,Wang SC,Cheng RH,Yeh CL,Tsui CC,Chia-Hung K

更新日期：2014-09-01 00:00:00