Totally automatic definition of renal regions of interest from 99mTc-MAG3 renograms: validation in patients with normal kidneys and in patients with suspected renal obstruction.

abstract：BACKGROUND:Early experience demonstrated absorbed dose in radiation synovectomy is about 100 Gy. For reaching this dose, the applied radioactivity should be calculated. METHOD:Twenty-nine synovitic models of rabbit were treated by intra-articular injection of [(188)Re]rhenium sulfide and histological changes of synovi...

journal_title：Nuclear medicine communications

authors： Li P,Yu J,Chen G,Jiang X,Tang Z,Chen S,Jiang L,Tang L,Yin D

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Image-derived input function (IDIF) from carotid arteries is an elegant alternative to full arterial blood sampling for brain PET studies. However, a recent study using blood-free IDIFs found that this method is particularly vulnerable to patient motion. The present study used both simulated and clinical [11...

journal_title：Nuclear medicine communications

authors： Zanotti-Fregonara P,Liow JS,Comtat C,Zoghbi SS,Zhang Y,Pike VW,Fujita M,Innis RB

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:Sickle cell disease (SCD) is a common hematologic hereditary disorder characterized by vaso-occlusive episodes affecting multiple organs, and substantially alters renal structure and function. We aimed to evaluate the utility of renal scintigraphy and single photon emission computed tomography/computed tomograp...

journal_title：Nuclear medicine communications

authors： Ramos CD,Onusic DM,Brunetto SQ,Amorim BJ,Souza TF,Saad STO,Lima MDCL

更新日期：2019-11-01 00:00:00

abstract：:The aim of the study was to evaluate pulmonary nodules (PNs) by incorporating time sensitivity (S) factor in the retention index (RI) and compare with the traditional fixed interval method. After obtaining approval from the Human Investigations Committee, 97 PNs from 81 patients (age=70±11) referred for dual-time fluo...

journal_title：Nuclear medicine communications

authors： Wong CY,Al-faham Z,Jolepalem P,Wong WW,Thie J

更新日期：2014-12-01 00:00:00

abstract：:Although several hypotheses have been suggested regarding the accumulation of 99Tc(m)-sestamibi in tumours, the exact uptake mechanism is still a matter of discussion. We investigated ultrastructural cell type of thyroid tumours by electron microscopy (EM) and compared them with uptake of 99Tc(m)-sestamibi. Thyroid sc...

journal_title：Nuclear medicine communications

authors： Sarikaya A,Huseyinova G,Irfanoğlu ME,Erkmen N,Cermik TF,Berkarda S

更新日期：2001-01-01 00:00:00

abstract：:Technetium-99m-galactosyl human serum albumin (99mTc-GSA) is a radiopharmaceutical that binds to asialoglycoprotein receptors in the hepatocyte membrane; the level of 99mTc-GSA accumulation in the liver correlates well with the parameters of hepatic function tests. We hypothesized that the early blood kinetics of 99mT...

journal_title：Nuclear medicine communications

authors： Sugai Y,Komatani A,Hosoya T,Takahashi K

更新日期：2001-07-01 00:00:00

abstract：:The level of Na(+)-K+ adenosine triphosphatase (ATPase) has been demonstrated to be correlated with tumour growth potential, and accelerated active transport of K+ carried out by Na(+)-K+ ATPase is said to be a trigger of 201Tl affinity for malignant tumour cells. Therefore, 201Tl scintigraphy appears to be a good ind...

journal_title：Nuclear medicine communications

authors： Suga K,Nishigauchi K,Fujita T,Nakanishi T

更新日期：1994-03-01 00:00:00

abstract：:Thallium-201 (201Tl) stress-redistribution/reinjection imaging provides a reliable diagnostic approach in patients evaluated for myocardial ischaemia. Immediate reinjection of 201Tl after completing the stress images followed by imaging 1 h later shortens the investigation time to 2.5 h and may provide a novel approac...

journal_title：Nuclear medicine communications

authors： van Eck-Smit BL,van der Wall EE,Zwinderman AH,Pauwels EK

更新日期：1995-10-01 00:00:00

abstract：:The aim of this study was to look for regional cerebral blood flow (rCBF) abnormalities in patients with a recent diagnosis of pseudotumour cerebri (PTC) and to compare 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) cerebral single photon emission tomographic (SPET) findings with those of X-ray computed tomograph...

journal_title：Nuclear medicine communications

authors： Bakar M,Tamgac F,Alper E,Zarifoglu M,Bora I,Turan F,Ogul E

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the prognostic significance of qualitative and quantitative F-fluorodeoxyglucose (F-FDG) PET-computed tomography (PET-CT) parameters in patients with recurrent cervical carcinoma. METHODS:Twenty-six patients (age: 44 ± 10.1 years) with histologically proven recurrent car...

journal_title：Nuclear medicine communications

authors： Maharjan S,Sharma P,Patel CD,Sharma DN,Dhull VS,Jain SK,Thulkar S,Malhotra A,Kumar R

更新日期：2013-08-01 00:00:00

abstract：:Radioiodinated meta-iodobenzylguanidine (MIBG) is used routinely for imaging and targeted radiotherapy of tumours derived from the neural crest. Since active uptake of MIBG by the noradrenaline transporter (NAT) makes a greater contribution to total drug accumulation than passive uptake when MIBG is present at low con...

journal_title：Nuclear medicine communications

authors： Owens J,Bolster AA,Prosser JE,Cunningham S,Mairs RJ,Neilly JB,Reed NS,Hilditch TE

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:The NHS National PET-CT Audit Programme was launched in 2008 as part of a national NHS programme to widen patient access to PET-computed tomography (CT) imaging in England. However, to implement clinical audit effectively, healthcare professionals need to be fully engaged with the process. The purpose of the pi...

journal_title：Nuclear medicine communications

authors： Ross P,Hubert J,Saunders M,Wong WL

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare the sensitivity of single-photon emission computed tomography/computed tomography (SPECT/CT) using 99mTc-sestamibi (MIBI) with that of PET/CT using 11C-methionine (MET) for localization of parathyroid adenomas/hyperplasia in primary hyperparathyroidism. MATERIALS AND ...

journal_title：Nuclear medicine communications

authors： Hayakawa N,Nakamoto Y,Kurihara K,Yasoda A,Kanamoto N,Miura M,Inagaki N,Togashi K

更新日期：2015-01-01 00:00:00

abstract：:Fluorine-18-sodium fluoride (F-NaF) PET/CT is a relatively new and high-resolution bone imaging modality. Since the use of F-NaF PET/CT has been increasing, it is important to accurately assess the images and be aware of normal distribution and major artifacts. In this pictorial review article, we will describe the no...

journal_title：Nuclear medicine communications

authors： Sarikaya I,Elgazzar AH,Sarikaya A,Alfeeli M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:A new kinetic model of technetium-99m-labeled diethylenetriaminepentaacetic acid-galactosyl human serum albumin (Tc-GSA) was developed to show the speed of asialoglycoprotein receptor-mediated endocytosis. MATERIALS AND METHODS:Ten healthy volunteers and 17 patients with liver cirrhosis were intravenously i...

journal_title：Nuclear medicine communications

authors： Du S,Mao Y,Tong J,Li F,Che L,Li S,Yang H,Ba J,Hu N,Xing H,Lu X,Sang X,Zhang X,Wang X,Zhong S

更新日期：2013-09-01 00:00:00

abstract：:This paper considers the different statistics that can be derived from studies on the value of diagnostic tests. Well-accepted quantities, such as sensitivity and specificity, are reviewed and the value of the likelihood ratio in communicating particular test results is highlighted. A new quantity, the 'diagnostic val...

journal_title：Nuclear medicine communications

authors： Lloyd JJ,Talbot PR,Lawson RS

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the degree and location of the reparative process in early osteonecrosis of the femoral head on the basis of single-photon emission computed tomography/computed tomography (SPECT/CT) with technetium-99m hydroxymethylene diphosphonate. MATERIALS AND METHODS:This study was ap...

journal_title：Nuclear medicine communications

authors： Motomura G,Yamamoto T,Abe K,Nakashima Y,Ohishi M,Hamai S,Doi T,Honda H,Iwamoto Y

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The new anti-cancer drug imatinib mesylate inhibits the tyrosine kinase growth factor receptor, c-KIT, and has shown spectacular activity in patients with gastrointestinal stromal tumours (GISTs). OBJECTIVE:To assess whether fluorodeoxyglucose positron emission tomography (FDG PET) is suitable for response ...

journal_title：Nuclear medicine communications

authors： Jager PL,Gietema JA,van der Graaf WT

更新日期：2004-05-01 00:00:00

abstract：:To evaluate the incidence, severity and clinical course of right ventricular (RV) involvement after acute inferior myocardial infarction (IMI), 78 patients (pts) with IMI were investigated by both 99Tcm-pyrophosphate (PYP) scan and gated blood pool scan (GBPS). GBPS was performed at admission and 10 days, whereas 99Tc...

journal_title：Nuclear medicine communications

authors： Nishimura T,Yasuda T,Gold HK,Leinbach RC,Boucher CA,McKusick KA,Strauss HW

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:Brain metastases are common in lung cancer. Whole-body 2-deoxy-2-[fluorine-18]fluoro-D-glucose ([F]FDG) PET/computed tomography (CT) is used for general staging, but MRI is the best modality for characterizing brain abnormalities. We aimed to determine whether PET/CT is suitable for selecting patients for MRI...

journal_title：Nuclear medicine communications

authors： Hjorthaug K,Højbjerg JA,Knap MM,Tietze A,Haraldsen A,Zacho HD,Kramer SM,Borghammer P

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:The goal of this study was to assess global cerebral glucose uptake in subjects with known cardiovascular risk factors by employing a quantitative F-fluorodeoxyglucose-PET/computed tomography (FDG-PET/CT) technique. We hypothesized that at-risk subjects would demonstrate decreased global brain glucose uptake co...

journal_title：Nuclear medicine communications

authors： Borja AJ,Hancin EC,Zhang V,Koa B,Bhattaru A,Rojulpote C,Detchou DK,Aly M,Kaghazchi F,Gerke O,Patil S,Gonuguntla K,Werner TJ,Revheim ME,Høilund-Carlsen PF,Alavi A

更新日期：2020-12-14 00:00:00

abstract：:The aim of this study was to assess, by positron emission tomography (PET), the effect on cerebral functional activity of a new lorazepam-gamma-aminobutyric acid (GABA) conjugate [3-(4-acetamido)-butyrril lorazepam (DDS2700)]. Ten healthy volunteers were studied by PET and [18F]fluoro-deoxy-D-glucose ([18F]FDG) under ...

journal_title：Nuclear medicine communications

authors： Moresco RM,Tettamanti M,Gobbo C,Del Sole A,Ravasi L,Messa C,Paulesu E,Lucignani G,Perani D,Fazio F

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic (18)F-fluorodeoxyglucose ((18)F-FDG) uptake. In this study, we focused on cytokines to investigate interactions during this phenomenon and clarify the significance of splenic (18)F-...

journal_title：Nuclear medicine communications

authors： Pak K,Kim SJ,Kim IJ,Kim DU,Kim K,Kim H

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to show the viability and performance of a shape-based pattern recognition technique applied to I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography (FP-CIT SPECT) in patients with parkinsonism. METHODS:A fully autom...

journal_title：Nuclear medicine communications

authors： Staff RT,Ahearn TS,Wilson K,Counsell CE,Taylor K,Caslake R,Davidson JE,Gemmell HG,Murray AD

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:Thermogenesis of brown adipose tissue (BAT) is controlled by central modulating mechanisms, although changes in brain metabolism of BAT-positive subjects with different genders are still unclear. We hypothesized that changes in regional cerebral glucose metabolic activity were associated with BAT activities, an...

journal_title：Nuclear medicine communications

authors： Shao X,Chen Y,Shao X,Wang S,Wang S,Wang Y

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:We investigated the localization pattern of a novel imaging agent, (99m)Tc-labelled glucosamine (ECDG), in a variety of rheumatic conditions. MATERIALS AND METHODS:Sixteen patients were recruited into the study, with either active rheumatoid arthritis or osteoarthritis. (99m)Tc-ECDG was prepared in-house an...

journal_title：Nuclear medicine communications

authors： Angelides S,El-Mashaleh M,Anagnostou M,Howe G,Spencer D,Kumar V,Manolios N

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:This study aimed to evaluate the efficacy of automatic exposure control (AEC) in order to optimize low-dose computed tomography (CT) protocols for patients of different ages undergoing cardiac PET/CT and single-photon emission computed tomography/computed tomography (SPECT/CT). METHODS:One PET/CT and one SPECT...

journal_title：Nuclear medicine communications

authors： Yang CC,Yang BH,Tu CY,Wu TH,Liu SH

更新日期：2017-06-01 00:00:00

abstract：:The method described by Weisner et al. for stabilizing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) with cobalt chloride hexahydrate solution is the most promising developed to date. The aim of our work was to study the behaviour of cobalt during the labelling of leukocytes with 99Tcm-HMPAO stabilized in vitro ...

journal_title：Nuclear medicine communications

authors： Prangere T,Bowden AD,Beauchat V,Caulier MT,Ziegels P,Huglo D,Pickett RD,Steinling M

更新日期：1997-03-01 00:00:00

abstract：:Fractionation of 99Tcm-exametazime enables several patients doses to be prepared from one vial. To overcome the disadvantages of storage at -70 degrees C, storage at higher temperatures was investigated with replacement of stannous ions before use. Kits were fractionated using a nitrogen-purged 0.9% w/v sodium chlorid...

journal_title：Nuclear medicine communications

authors： Baker RJ

更新日期：1999-03-01 00:00:00

abstract：:Polyphosphonate ligands labelled with radioisotopes decaying by moderate energy beta emission have shown utility as palliative agents for painful bone metastasis. 177Lu (T(1/2)=6.71 d, Ebetamax=497 keV) has radionuclidic properties suitable for use in palliative therapy of bone metastasis. 177Lu was produced at a high...

journal_title：Nuclear medicine communications

authors： Chakraborty S,Das T,Unni PR,Sarma HD,Samuel G,Banerjee S,Venkatesh M,Ramamoorthy N,Pillai MR

更新日期：2002-01-01 00:00:00