Preparation and properties of 99Tcm-exametazime using stannous ion augmentation of fractionated cold kits.

abstract：BACKGROUND:The new anti-cancer drug imatinib mesylate inhibits the tyrosine kinase growth factor receptor, c-KIT, and has shown spectacular activity in patients with gastrointestinal stromal tumours (GISTs). OBJECTIVE:To assess whether fluorodeoxyglucose positron emission tomography (FDG PET) is suitable for response ...

journal_title：Nuclear medicine communications

authors： Jager PL,Gietema JA,van der Graaf WT

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:Renal ischemia-reperfusion injury (RIRI) may occur secondary to several reasons leading to renal failure. Coenzyme-Q10 (CoQ10) is a well-known antioxidant. However, the effects CoQ10 against RIRI have not been evaluated. Our aim was to evaluate protective effects of CoQ10 to renal ischemia-reperfusion by bioche...

journal_title：Nuclear medicine communications

authors： Akbulut A,Keseroglu BB,Koca G,Yuceturk CN,Ozgur BC,Surer H,Ogus E,Yumuşak N,Karakaya J,Korkmaz M

更新日期：2019-10-01 00:00:00

abstract：:Radionuclide limb blood flow measurements using 99Tcm-labelled human serum albumin and a gamma camera have been performed on normal volunteers and on patients with suspected or confirmed peripheral arterial disease. The normal range of flow was found to be 10.0-22.3 ml per 100 ml tissue per min. Flow in the symptomati...

journal_title：Nuclear medicine communications

authors： Parkin A,Robinson PJ,Martinez D,Wilkinson D,Kester RC

更新日期：1991-10-01 00:00:00

abstract：:High-grade astrocytoma represents the most common primary malignant brain tumour in the adult, and is associated with high morbidity and mortality rates. The aim of this study was to investigate the prognostic value of 99Tcm-hexamethylpropyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT...

journal_title：Nuclear medicine communications

authors： Rodrigues M,Fonseca AT,Salgado D,Vieira MR

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:Radionuclide therapies, including treatment of neuroendocrine tumors with lutetium-177 (Lu-177) octreotate, often involve hospital admission to minimize radiation exposure to the public. Overnight admission due to Lu-177 octreotate therapy incurs additional cost for the hospital and is an inconvenience for t...

journal_title：Nuclear medicine communications

authors： Olmstead C,Cruz K,Stodilka R,Zabel P,Wolfson R

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:This study investigated dopamine transporter blockade in the rat striatum after treatment with various doses of methylphenidate using a high-resolution small animal SPECT ('TierSPECT') and I-FP-CIT. METHODS:I-FP-CIT was administered intravenously 1 h after intraperitoneal injection of methylphenidate (3 mg.k...

journal_title：Nuclear medicine communications

authors： Nikolaus S,Antke C,Beu M,Kley K,Larisch R,Wirrwar A,Müller HW

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:In the present study, (99m)Tc-radiolabelled E-selectin binding peptide ((99m)Tc-IMP-178) was investigated for its potential to image acute pyogenic osteomyelitis in a new animal model. Intraindividual comparisons were performed using an irrelevant peptide ((99m)Tc-IMP-100) to demonstrate specificity. METH...

journal_title：Nuclear medicine communications

authors： Gratz S,Béhé M,Boerman OC,Kunze E,Schulz H,Eiffert H,O'Reilly T,Behr TM,Angerstein C,Nebendahl K,Kauer F,Becker W

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Human serum albumin (HSA), which has 58 Lys residues, one Cys residue, and indocyanine green (ICG) adsorption sites, can be used as a multifunctional platform for the development of hybrid imaging probes. In this study, we prepared 64Cu-labeled mannose-conjugated HSA with and without ICG ([64Cu]1-ICG and [64C...

journal_title：Nuclear medicine communications

authors： Kang CM,An GI,Choe YS

更新日期：2015-10-01 00:00:00

abstract：:Following androgen ablation therapy, skeletal metastases from prostate cancer appear in some instances to show an increase in 99Tcm-methylene diphosphonate (99Tcm-MDP) uptake. Such a phenomenon could represent a mechanism to increase delivery of bone-seeking therapeutic agents to skeletal metastatic sites. The aim of ...

journal_title：Nuclear medicine communications

authors： Bushnell DL,Madsen M,Kahn D,Nathan M,Williams RD

更新日期：1999-10-01 00:00:00

abstract：:Equilibrium radionuclide angiography (ERNA) is the 'gold standard' for assessing left ventricular ejection fraction (LVEF). The aim of the study was to determine whether the left ventricular cavity-to-myocardium count ratio (LVCMR) from 201Tl myocardial single photon emission computed tomography (SPECT) correlated wit...

journal_title：Nuclear medicine communications

authors： Maunoury C,Antonietti T,Sebahoun S,Barritault L

更新日期：2001-03-01 00:00:00

abstract：AIM:The purpose of this case-control study was to determine whether semi-quantitative indices derived from salivary time-activity curves (TACs) are useful in the diagnosis and management of xerostomia. METHODS:Twenty-six healthy volunteers and 83 consecutive patients with xerostomia, including a subset of 40 patients ...

journal_title：Nuclear medicine communications

authors： Booker J,Howarth D,Taylor L,Voutnis D,Sutherland D

更新日期：2004-12-01 00:00:00

abstract：:A significant reduction of cardiac 123I-meta-iodobenzylguanidine (MIBG) accumulation has been reported in patients with idiopathic Parkinson's disease. However, it is unclear whether this reduction in cardiac sympathetic nerve is caused primarily or secondarily to the degeneration of sympathetic nerve centres which oc...

journal_title：Nuclear medicine communications

authors： Takatsu H,Wada H,Maekawa N,Takemura M,Saito K,Fujiwara H

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...

journal_title：Nuclear medicine communications

authors： Cohen JB,Kalinyak JE,McDougall IR

更新日期：2004-02-01 00:00:00

abstract：:Fifty-six patients with hypertrophic cardiomyopathy who had echocardiography and cardiac catheterization were studied. Eleven (18%) of 56 patients had right ventricular (RV) thallium-201 visualization at resting scan. RV thallium-201 visualization was observed in the apex or lower half of the RV free wall, which was q...

journal_title：Nuclear medicine communications

authors： Nishimura T,Uehara T,Hayashida K,Nagata S

更新日期：1988-01-01 00:00:00

abstract：AIM:It has been reported that dyslipidaemia impairs left ventricular systolic (LVs) and diastolic (LVd) functions, irrespective of atherogenic effects, in the setting of coronary artery disease. The aim of the present study was to evaluate the effects of anti-lipidaemic therapy on LVs and LVd functions by means of mult...

journal_title：Nuclear medicine communications

authors： Entok E,Unalir A,Cavusoglu Y,Timuralp B,Vardareli E

更新日期：2005-09-01 00:00:00

abstract：:Heart uptake and clearance of 123I-15-(p-iodophenyl)-3(R,S)-methyl- pentadecanoic acid (BMIPP) by whole-body scintigraphy in relation to left ventricular ejection fraction (LVEF) was evaluated in 34 patients with ischaemic heart disease. At 45 and 210 min after injection, anterior whole-body images were obtained. In e...

journal_title：Nuclear medicine communications

authors： Matsunari I,Saga T,Taki J,Akashi Y,Wakasugi T,Hirai JI,Aoyama T,Matoba M,Nishikawa T,Ichiyanagi K

更新日期：1994-09-01 00:00:00

abstract：:The biodistribution of 131I-6 beta-iodomethyl-19-norcholesterol (NP-59) was assessed in hypercholesterolaemic patients and in a rabbit model of HC to examine the alterations in the relative distribution of NP-59 and its metabolites and to explain the changes in the patterns of adrenal cortical imaging in patients with...

journal_title：Nuclear medicine communications

authors： Lynn MD,Gross MD,Shapiro B,Bassett D

更新日期：1986-08-01 00:00:00

abstract：:An examination of the biokinetics and biodistribution of i.p. administered 131I- or 111In-labelled 791T/36 antibody (1 mg) has been carried out in five patients with stage III/IV ovarian cancer. Blood kinetics and urinary excretion of the radiolabels were assayed. Scintigraphy was performed immediately following admin...

journal_title：Nuclear medicine communications

authors： Perkins AC,Pimm MV,Gie C,Marksman RA,Symonds EM,Baldwin RW

更新日期：1989-08-01 00:00:00

abstract：:The requirements, problems and progress of radioimmunotherapy in the management of certain malignancies are described. The future prospects using a two- or three-stage approach are promising. ...

journal_title：Nuclear medicine communications

authors： Britton KE,Mather SJ,Granowska M

更新日期：1991-04-01 00:00:00

abstract：PURPOSE:Lymphoid hyperplasia is not uncommon in the midline roof of the nasopharynx. Most nasopharyngeal carcinoma patients present with primary tumors in the midline of the nasopharynx. The aim of this study was to evaluate the efficacy of 2-[fluorine-18] fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/computed tomography (C...

journal_title：Nuclear medicine communications

authors： Chen YK,Wang SC,Cheng RH,Yeh CL,Tsui CC,Chia-Hung K

更新日期：2014-09-01 00:00:00

abstract：:In order to evaluate the utility of positron emission tomography (PET) with 18F-labelled deoxyglucose (FDG) for detection of pancreatic cancer 15 patients with pancreatic masses shown by computed tomography were investigated. Static PET scans covering an axial field of view of 15 cm were obtained 45 min after intraven...

journal_title：Nuclear medicine communications

authors： Bares R,Klever P,Hellwig D,Hauptmann S,Fass J,Hambuechen U,Zopp L,Mueller B,Buell U,Schumpelick V

更新日期：1993-07-01 00:00:00

abstract：AIMS:Peptide receptor radionuclide therapy (PRRT) has been shown to be useful in inoperable/metastatic medullary thyroid carcinoma (MTC). However, the role of concomitant PRRT and low-dose capecitabine therapy has not yet been studied in these patients. This study was conducted to evaluate the efficacy and safety of th...

journal_title：Nuclear medicine communications

authors： Satapathy S,Mittal BR,Sood A,Verma R,Panda N

更新日期：2020-07-01 00:00:00

abstract：:High-quality positron emission tomographic (PET) cameras are expensive and, therefore, not available in many centres. To allow access to clinical 18F-fluorodeoxyglucose (18F-FDG) PET, we began working with an ADAC Vertex camera equipped with a molecular coincidence detection (MCD) module in February 1997. Here we give...

journal_title：Nuclear medicine communications

authors： Erler H,Zaknun J,Donnemiller E,Bacher-Stier C,Oberladstätter M,Riccabona G,Moncayo R

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:The present study was undertaken to evaluate the ablation rate after administration of 1.1 or 3.7 GBq of iodine- (¹³¹I) to patients with low-risk differentiated thyroid carcinoma (DTC) primarily treated by lobectomy. PATIENTS AND METHODS:Enrolled were 136 consecutive patients affected by histologically proven ...

journal_title：Nuclear medicine communications

authors： Giovanella L,Piccardo A,Paone G,Foppiani L,Treglia G,Ceriani L

更新日期：2013-08-01 00:00:00

abstract：:The viability of autologous adrenal medullary transplants was evaluated using 125I-meta-iodobenzyl guanidine (MIBG), an adrenal medullary scanning agent. Bilateral cavities in the caudate nuclei were made stereotaxically in Wistar rats. One week later, the left adrenal medulla was resected by microsurgery, followed by...

journal_title：Nuclear medicine communications

authors： Shinoda M,Suzuki Y,Oi S,Tsugane R,Sato O

更新日期：1994-09-01 00:00:00

abstract：:N-isopropyl-p-I-123-iodoamphetamine (123I-IMP) is extracted by the brain in proportion to regional blood flow. It is particularly useful in the clinical assessment of various pathological conditions related to altered cerebral flow. Moreover, it has been reported that 123I-IMP is avidly incorporated into melanin and m...

journal_title：Nuclear medicine communications

authors： Watanabe N,Seto H,Yokoyama K,Matsuda H,Shimizu M,Tonami N,Hisada K,Kakishita M

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the efficacy of low-dose and high-dose (99m)Tc methoxy isobutyl isonitrile (MIBI) protocols in intraoperative localization of parathyroid adenomas by means of a gamma probe in patients with primary hyperparathyroidism (PHPT). PATIENTS AND METHODS:The study included 62 pat...

journal_title：Nuclear medicine communications

authors： Gencoglu EA,Aras M,Moray G,Aktas A

更新日期：2014-04-01 00:00:00

abstract：:Medullary thyroid cancer (MTC) arises from parafollicular C cells and is an elusive tumor to image. It occurs as a sporadic neoplasm in 70-80% of cases and is hereditary in 20-30% because of germline mutations of the rearranged during transfection proto-oncogene. Successful disease management relies on accurate stagin...

journal_title：Nuclear medicine communications

authors： Wong KK,Laird AM,Moubayed A,Chondrogiannis S,Marzola MC,Evangelista L,Gross MD,Rubello D

更新日期：2012-07-01 00:00:00

abstract：AIM:To test the applicability of Tc-dextran joint scintigraphy in the assessment of disease activity in patients with rheumatoid arthritis (RA), and to compare it with the clinical disease activity scores and laboratory parameters. METHODS:Twenty-seven patients with RA were investigated using Tc-dextran joint scintigr...

journal_title：Nuclear medicine communications

authors： Kaya M,Tuna H,Fatih Firat M,Tuna F,Seren G,Necmi Yigitbasi O

更新日期：2004-06-01 00:00:00

abstract：:Single kidney clearance can be obtained using the 99Tcm-DTPA complex and the scintillation camera. In order to evaluate the influence of statistical noise on the determination of the clearance, several non-noisy curves were constructed, simulating renal, background and precordial curves. Poisson noise was added to the...

journal_title：Nuclear medicine communications

authors： Piepsz A,Dobbeleir A,Ham HR

更新日期：1985-08-01 00:00:00