Radiolabelled monoclonal antibodies in oncology. III. Radioimmunotherapy.

abstract：INTRODUCTION:It has been suggested that renal retention function can be estimated by differentiation of the Patlak-Rutland plot. AIM:To evaluate the error resulting from this method. METHODS:A total of 5800 renograms were generated by convolving real input functions with artificial retention functions. Ten bi-exponen...

journal_title：Nuclear medicine communications

authors： Kuyvenhoven JD,Ham HR,Piepsz A

更新日期：2004-05-01 00:00:00

abstract：:A general method is presented for fitting experimental data to arbitrary linear compartmental models, based on readily available public domain software. The model is defined by input data so that the same program can be used for different compartmental models. Its use is exemplified by application to the four-compartm...

journal_title：Nuclear medicine communications

authors： Russell CD

更新日期：2001-08-01 00:00:00

abstract：:We performed a prospective study to establish the optimal background correction algorithm for the determination of differential renal function (DRF), using 99Tc(m)-diethylenetriamine pentaacetate (99Tc(m)-DTPA) in the presence of unilateral hydronephrosis, with 24 h 99Tc(m)-dimercaptosuccinic acid (99Tc(m)-DMSA) uptak...

journal_title：Nuclear medicine communications

authors： Van de Wiele C,De Sadeleer C,Koole M,D'Asseler Y,Everaert K,Dierckx RA

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Patients with normal stress perfusion have an excellent prognosis. Prospective studies on the diagnostic accuracy of stress-only scans with contemporary, independent examinations as gold standards are lacking. PATIENTS AND METHODS:A total of 109 patients with typical angina and no previous coronary artery di...

journal_title：Nuclear medicine communications

authors： Ejlersen JA,May O,Mortensen J,Nielsen GL,Lauridsen JF,Allan J

更新日期：2017-11-01 00:00:00

abstract：:Measurements were made of the concentration of radioactivity in the breast milk of two patients: one following 100 MBq (2.7 mCi) 99Tcm-pertechnetate administration, and the other following administration of 550 MBq (15 mCi) 99Tcm-glucoheptonate. The fractional activity concentrations in the former case were about two ...

journal_title：Nuclear medicine communications

authors： Mountford PJ,Coakley AJ

更新日期：1987-10-01 00:00:00

abstract：:The ability of 99Tcm-methoxyisobutylisonitrile (MIBI) single photon emission tomography (SPET) to detect myocardial ischaemia and necrosis was assessed in 56 patients (45 male, 11 female, aged 55 +/- 5 years), with clinically recognized ischaemic heart disease (IHD). All underwent coronary angiography (CA) and left ve...

journal_title：Nuclear medicine communications

authors： Sciammarella MG,Fragasso G,Gerundini P,Maffioli L,Cappelletti A,Margonato A,Savi A,Chierchia S

更新日期：1992-12-01 00:00:00

abstract：AIM:In patients with differentiated thyroid carcinoma (DTC), metastases can either show iodine-131 (I) uptake on whole-body scintigraphy or F-2-fluoro-2-deoxy-D-glucose (F-FDG) uptake on combined PET and X-ray computed tomography (PET/CT), or a mix of both. The present study investigates the relationship between uptake...

journal_title：Nuclear medicine communications

authors： Kelders A,Kennes LN,Krohn T,Behrendt FF,Mottaghy FM,Verburg FA

更新日期：2014-02-01 00:00:00

abstract：:The purpose of this study was to compare six methods of measuring the left ventricular (LV) transient ischaemic dilation (TID) ratio during stress-rest myocardial perfusion single-photon emission tomography (SPET). The TID ratio was defined as the mean LV short-axis area at stress divided by the mean LV area of simila...

journal_title：Nuclear medicine communications

authors： Peace RA,McKiddie FI,Staff RT,Gemmell HG

更新日期：2000-10-01 00:00:00

abstract：:The British Nuclear Medicine Society has developed a process for the service-specific organizational audit of nuclear medicine departments. This process identified the need for a scheme suitable for the audit of the scientific and technical standards of a department providing such a service. This document has evolved ...

journal_title：Nuclear medicine communications

authors： Jarritt PH,Perkins AC,Woods SD,British Nuclear Medicine Society.

更新日期：2004-08-01 00:00:00

abstract：:To study the accuracy of renal function quantification with 99Tcm-DMSA we compared DMSA renal uptake and creatinine clearance in 16 cases of children with single kidney. The age of the patients ranged from two months to fourteen years. Creatinine clearance was normalized to 1.73 m2. DMSA uptake was measured 7 h after ...

journal_title：Nuclear medicine communications

authors： Baillet G,Gagnadoux MF,De Vernejoul P,Broyer M

更新日期：1985-11-01 00:00:00

abstract：:Following androgen ablation therapy, skeletal metastases from prostate cancer appear in some instances to show an increase in 99Tcm-methylene diphosphonate (99Tcm-MDP) uptake. Such a phenomenon could represent a mechanism to increase delivery of bone-seeking therapeutic agents to skeletal metastatic sites. The aim of ...

journal_title：Nuclear medicine communications

authors： Bushnell DL,Madsen M,Kahn D,Nathan M,Williams RD

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Clinical studies in women using technetium-99m (Tc)-Bombesin have shown successful radionuclide imaging of breast tumours overexpressing gastrin-releasing peptide receptors (GRPRs). Recent studies have demonstrated that most breast tumours overexpress folate receptors (FRα). AIM:The aim of this work was to ...

journal_title：Nuclear medicine communications

authors： Aranda-Lara L,Ferro-Flores G,Ramírez Fde M,Ocampo-García B,Santos-Cuevas C,Díaz-Nieto L,Isaac-Olivé K

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the accuracy of the sequential multiphase and dual-tracer (SMADT) technique utilizing technetium-99m pertechnetate (99mTcO4) and dynamic technetium-99m-2-methoxyisobutylisonitrile (99mTc-MIBI) with single-photon emission computed tomography/computed tomography (SPECT/CT) f...

journal_title：Nuclear medicine communications

authors： Berner AM,Haroon A,Nowosinska E,Offiah C,Luqman M,Newell M,Jan H

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:We retrospectively investigated the value of dynamic Tc-diisopropyl-iminodiacetic acid hepatobiliary scintigraphy (HBS) in discriminating postsurgical complications following liver transplantation (LT). METHODS:Dynamic HBS was performed for suspected post-LT complications in 201 cases. Hepatic uptake and exc...

journal_title：Nuclear medicine communications

authors： Lee JY,Hu W,Lee KH,Kwon CH,Lee EJ,Choi JY,Kim BT

更新日期：2012-03-01 00:00:00

abstract：:A significant reduction of cardiac 123I-meta-iodobenzylguanidine (MIBG) accumulation has been reported in patients with idiopathic Parkinson's disease. However, it is unclear whether this reduction in cardiac sympathetic nerve is caused primarily or secondarily to the degeneration of sympathetic nerve centres which oc...

journal_title：Nuclear medicine communications

authors： Takatsu H,Wada H,Maekawa N,Takemura M,Saito K,Fujiwara H

更新日期：2002-02-01 00:00:00

abstract：:A method for attenuation and scatter correction of brain single photon emission computed tomography (SPECT) is described where computed tomography (CT) images of the brain are used for the calculation of attenuation maps. The method is evaluated for the substance 99mTc hexamethylpropylene amine oxime. A transmission d...

journal_title：Nuclear medicine communications

authors： Larsson A,Johansson L,Sundström T,Ahlström KR

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:The goal of this study was to assess global cerebral glucose uptake in subjects with known cardiovascular risk factors by employing a quantitative F-fluorodeoxyglucose-PET/computed tomography (FDG-PET/CT) technique. We hypothesized that at-risk subjects would demonstrate decreased global brain glucose uptake co...

journal_title：Nuclear medicine communications

authors： Borja AJ,Hancin EC,Zhang V,Koa B,Bhattaru A,Rojulpote C,Detchou DK,Aly M,Kaghazchi F,Gerke O,Patil S,Gonuguntla K,Werner TJ,Revheim ME,Høilund-Carlsen PF,Alavi A

更新日期：2020-12-14 00:00:00

abstract：OBJECTIVE:This study investigated dopamine transporter blockade in the rat striatum after treatment with various doses of methylphenidate using a high-resolution small animal SPECT ('TierSPECT') and I-FP-CIT. METHODS:I-FP-CIT was administered intravenously 1 h after intraperitoneal injection of methylphenidate (3 mg.k...

journal_title：Nuclear medicine communications

authors： Nikolaus S,Antke C,Beu M,Kley K,Larisch R,Wirrwar A,Müller HW

更新日期：2007-03-01 00:00:00

abstract：:Chronic synovitis often occurs in people with haemophilia. Untreated chronic haemophilic synovitis affects the metabolism of chondrocytes, thus leading to haemophilic arthropathy. A recently introduced therapeutic protocol includes radiation synovectomy (RS), a safe and cost-effective therapeutic method, which has giv...

journal_title：Nuclear medicine communications

authors： Teyssler P,Kolostova K,Bobek V

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Sickle cell disease (SCD) is a common hematologic hereditary disorder characterized by vaso-occlusive episodes affecting multiple organs, and substantially alters renal structure and function. We aimed to evaluate the utility of renal scintigraphy and single photon emission computed tomography/computed tomograp...

journal_title：Nuclear medicine communications

authors： Ramos CD,Onusic DM,Brunetto SQ,Amorim BJ,Souza TF,Saad STO,Lima MDCL

更新日期：2019-11-01 00:00:00

abstract：:System upgrades are a constant feature of many highly technical specialties and are normally assumed to have a negligible effect on patient data. We report on the assessment of an upgrade made to a Norland XR-26 dual-energy X-ray absorptiometry (DXA) system. The upgraded version (2.3) consisted of new hip positioning ...

journal_title：Nuclear medicine communications

authors： Simmons A,Barrington SF,Archbold LJ,O'Doherty MJ,Coakley AJ

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:Many studies have attempted to assess the significance of the use of the β(-)particle emitter praseodymium-142 ((142)Pr) in cancer treatment. As praseodymium oxide (Pr(2)O(3)) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable ...

journal_title：Nuclear medicine communications

authors： Bakht MK,Sadeghi M,Ahmadi SJ,Sadjadi SS,Tenreiro C

更新日期：2013-01-01 00:00:00

abstract：:Orofacial granulomatosis is a granulomatous inflammatory disorder, affecting the soft tissues of the face and mouth. The predominant feature is disfiguring lip swelling. Patients with this condition may be exhibiting a Type IV hypersensitivity reaction to dietary or environmental allergens, or these may be the orofaci...

journal_title：Nuclear medicine communications

authors： Gibson J,Neilly JB,Wray AP,Evans TJ,MacKenzie JR,McKillop JH

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the evolution of patients with internal mammary chain (IMC) drainage whether the IMC-sentinel lymph node (IMC-SLN) was biopsied or not, as well as to determine the clinical implications of the biopsy of the IMC-SLN (IMC-SLNB) in patients with breast cancer and IMC drainag...

journal_title：Nuclear medicine communications

authors： Domènech-Vilardell A,Bajén MT,Benítez AM,Ricart Y,Mora J,Rodríguez-Bel L,García-Tejedor A,Climent J,López-Ojeda A,Urruticoechea A,Martín-Comín J

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:Respiratory gated perfusion single photon emission computed tomography (SPECT) was applied to reduce respiratory lung motion effects and to reliably assess perfusion impairment in various lung diseases. METHODS:After injection of 259 MBq of 99mTc macroaggretated albumin (99mTc-MAA), gating was performed using ...

journal_title：Nuclear medicine communications

authors： Suga K,Kawakami Y,Zaki M,Yamashita T,Matsumoto T,Matsunaga N

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:The determination of lesion boundaries on FDG PET is difficult due to the point-spread blurring and unknown uptake of activity within a lesion. Standard threshold-based methods for volumetric quantification on PET usually neglect any size dependence and are biased by dependence on the signal-to-background ra...

journal_title：Nuclear medicine communications

authors： van Dalen JA,Hoffmann AL,Dicken V,Vogel WV,Wiering B,Ruers TJ,Karssemeijer N,Oyen WJ

更新日期：2007-06-01 00:00:00

abstract：:LL1, a monoclonal antibody (MAb) to HLA Class-II-like antigen (li determinant) on the surface of B-lymphocytes, monocytes and histiocytes, was evaluated as an agent for bone marrow imaging. Six patients with diverse diseases (non-Hodgkin's lymphoma, n = 2; multiple myeloma, n = 1; polycythaemia vera, n = 1; lung cance...

journal_title：Nuclear medicine communications

authors： Juweid M,Dunn RM,Sharkey RM,Rubin AD,Hansen HJ,Goldenberg DM

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:99mTc-depreotide (NeoTect) is a synthetic somatostatin analogue, which binds to somatostatin receptor (SSTR) subtypes 2, 3 and 5. Imaging patients with non-Hodgkin's lymphoma (NHL) using the somatostatin analogue In-pentetreotide (Octreoscan) has demonstrated the feasibility of identifying lymphoma sites wit...

journal_title：Nuclear medicine communications

authors： Bushnell DL,Menda Y,Madsen MT,Link BK,Kahn D,Truhlar SM,Juweid M,Shannon M,Murguia JS

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Our objective was to analyze the clinical management and the outcome of disease in differentiated thyroid carcinoma with initial and late distant metastases (M1). PATIENTS AND METHODS:Radioiodine (131I) therapy was applied in 77 differentiated thyroid carcinoma patients with M1 (31 patients with M1-initial a...

journal_title：Nuclear medicine communications

authors： Mihailovic JM,Stefanovic LJ,Malesevic MD,Erak MD,Tesanovic DD

更新日期：2009-07-01 00:00:00

abstract：BACKROUND:Human tumors show intrinsic heterogeneity and changes in phenotype during disease progression, which implies different expression levels of cell surface receptors. The research on new heterodimeric lutetium-177 (Lu)-radiopharmaceuticals interacting with two different targets on tumor cells is a strategy for i...

journal_title：Nuclear medicine communications

authors： Escudero-Castellanos A,Ocampo-García B,Ferro-Flores G,Santos-Cuevas C,Morales-Ávila E,Luna-Gutiérrez M,Isaac-Olivé K

更新日期：2019-03-01 00:00:00