Abstract:
OBJECTIVE:We retrospectively investigated the value of dynamic Tc-diisopropyl-iminodiacetic acid hepatobiliary scintigraphy (HBS) in discriminating postsurgical complications following liver transplantation (LT). METHODS:Dynamic HBS was performed for suspected post-LT complications in 201 cases. Hepatic uptake and excretion was visually graded. The portal perfusion index (PPI) and kinetic parameters were quantitatively analyzed. RESULTS:HBS findings were normal in all 119 (59%) cases without complications. Complications were confirmed in 82 cases: 24 had graft rejection, 48 had biliary obstruction, and 10 had hepatitis. Visual grades of uptake and excretion were abnormal for all three types of complications and showed no discriminative value. The PPI level was significantly higher for grafts with rejection (0.83 ± 0.07) compared with no complication (0.57 ± 0.08), biliary obstruction (0.69 ± 0.06), and hepatitis (0.65 ± 0.07; all P<0.0001). Receiver operating characteristic curve analysis confirmed PPI to be highly accurate for discerning rejection from no rejection (area under the curve, 0.97; sensitivity, 95.8%; specificity, 91.7%) or biliary obstruction (area under the curve, 0.93; sensitivity, 95.8%; specificity, 79.2%). CONCLUSION:PPI measured from dynamic HBS offers a highly accurate method for identifying post-LT rejection and distinguishing it from biliary obstruction or hepatitis.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Lee JY,Hu W,Lee KH,Kwon CH,Lee EJ,Choi JY,Kim BTdoi
10.1097/MNM.0b013e32834fc5e6subject
Has Abstractpub_date
2012-03-01 00:00:00pages
255-61issue
3eissn
0143-3636issn
1473-5628journal_volume
33pub_type
杂志文章abstract:OBJECTIVE:The aim of this study was to compare the efficacy of low-dose and high-dose (99m)Tc methoxy isobutyl isonitrile (MIBI) protocols in intraoperative localization of parathyroid adenomas by means of a gamma probe in patients with primary hyperparathyroidism (PHPT). PATIENTS AND METHODS:The study included 62 pat...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000056
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:N staging is a key factor when considering the choice of treatment for non-small-lung cancer. It is possible that there is a correlation between N2 metastasis and some risk factors. The objective of the present study was to evaluate associations between several risk factors and N(2) metastasis using univaria...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000144
更新日期:2014-09-01 00:00:00
abstract::Positron emission tomography (PET) using F-18 fluoro-3'-deoxy-3-L-fluorothymidine (FLT) offers noninvasive assessment of cell proliferation in vivo. The most important application refers to the evaluation of tumour proliferative activity, representing a key feature of malignancy. Most data to date suggest that FLT is ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/MNM.0b013e32832ee93b
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:We investigated the role of Ga-68 DOTATATE PET/CT in comparison to F-18 FDG PET/CT in patients with low and intermediate versus high-grade neuroendocrine tumors (NETs). METHODS:We identified 81 patients who underwent Ga-68 DOTATATE PET/CT at our institution between May 2017 and December 2018 and met inclusio...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001255
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200402000-00006
更新日期:2004-02-01 00:00:00
abstract::Fifty-six patients with hypertrophic cardiomyopathy who had echocardiography and cardiac catheterization were studied. Eleven (18%) of 56 patients had right ventricular (RV) thallium-201 visualization at resting scan. RV thallium-201 visualization was observed in the apex or lower half of the RV free wall, which was q...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:The indocyanine green retention rate at 15 min (ICGR15) is a gold standard parameter of liver function when deciding on the extent of hepatectomy. However, ICGR15 is influenced by several hepatic conditions. To evaluate auxiliary preoperative liver functional reserve, we examined the clinical significance of...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001162
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the success rate in lymphatic mapping and sentinel node biopsy in breast cancer using two radiopharmaceuticals. METHODS:The study included 119 breast cancer patients who underwent lymphoscintigraphy after a single intratumoral injection of 99mTc-labelled human albumin co...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200403000-00004
更新日期:2004-03-01 00:00:00
abstract::In order to perform automatically the thresholding of the amplitude image obtained by phase analysis, a filter based on the probability density of the amplitude is proposed. It generates the image of the significant amplitude by setting to zero the amplitude if its square is lower than 4a0 log(1/alpha)/N where a0 is t...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198710000-00005
更新日期:1987-10-01 00:00:00
abstract:AIM:To perform a detailed analysis of the performance of mobile intraoperative imaging systems and gamma probes in a phantom set-up, and compare this with a conventional gamma camera. METHODS:Two separate experiments were performed. In the first, a modified Jaszczak phantom equipped with five (99m)Tc-filled hot sphere...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283508577
更新日期:2012-05-01 00:00:00
abstract::Pentavalent 99Tcm-dimercaptosuccinic acid (99Tcm-(V)DMSA) has an established role in imaging medullary thyroid carcinoma. There have been case reports of uptake in bone metastases. Our aims were to compare 99Tcm-(V)DMSA with 99Tcm-hydroxymethylene diphosphonate (99Tcm-HDP) in bone metastases, to assess its value in im...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-199710000-00003
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVES:Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic (18)F-fluorodeoxyglucose ((18)F-FDG) uptake. In this study, we focused on cytokines to investigate interactions during this phenomenon and clarify the significance of splenic (18)F-...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e3283595cac
更新日期:2013-01-01 00:00:00
abstract::Impaired cardiac fatty acid uptake, assessed by the radiolabelled fatty acid analogue beta-methyl-p-iodophenyl pentadecanoic acid (I-123-BMIPP), is observed in the myocardium following acute ischaemic events, but the long-term prognostic implication has not been established. This study aimed to determine the prognosti...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,多中心研究
doi:10.1097/00006231-200010000-00003
更新日期:2000-10-01 00:00:00
abstract::There is a lack of systematic nephrographic studies on epidemic nephritis (EN). We studied 10 patients with EN using [99Tcm]MAG3 gamma camera nephrography and followed up 9 of them 22-68 days later when they had clinically recovered. Variables for renal clearance of [99Tcm]MAG3 and the retention of radioactivity in th...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199101000-00003
更新日期:1991-01-01 00:00:00
abstract:AIM:To test the applicability of Tc-dextran joint scintigraphy in the assessment of disease activity in patients with rheumatoid arthritis (RA), and to compare it with the clinical disease activity scores and laboratory parameters. METHODS:Twenty-seven patients with RA were investigated using Tc-dextran joint scintigr...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/01.mnm.0000126632.32413.2e
更新日期:2004-06-01 00:00:00
abstract::The aims of this study were (1) to compare N-isopropyl-p-[I-123]-iodoamphetamine (123I-IMP) SPET with computed tomography (CT) in chronic-stage head trauma patients with neurological abnormalities and (2) to quantify regional cerebral blood flow (rCBF) in patients with chronic-stage head trauma. 123I-IMP SPET and CT w...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199501000-00006
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:Neurokinin 1 (NK1) receptors have been implicated in depression, anxiety, and pain perception. Recently, it was shown that, in the human brain, a specific NK1 receptor-related signal was obtained with the novel radioligand, [¹¹C]R116301, using positron emission tomography. The purpose of this study was to evalu...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e328347e96f
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:The standard imaging used for delineation of dominant intraprostatic lesion (DIL) is multiparametric MRI (mpMRI). The use of biologic imaging such as Ga-68 prostate-specific membrane antigen (PSMA) PET-computed tomography (PET-CT) for this purpose is being explored in view of increased sensitivity of this modal...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001283
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To analyse the kinetic changes of uptake, washout and retention of Tc-sestamibi in order to evaluate the protective effects and possible mechanism of ischaemic preconditioning and adenosine preconditioning on myocardium injured by ischaemia/reperfusion. METHODS:Isolated ischaemia/reperfusion rabbit heart mod...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f1781b
更新日期:2007-11-01 00:00:00
abstract::The effect of the dual window scatter subtraction method was tested for first-pass radiocardiography using 99Tcm. The photopeak window of 126-154 keV (20%) and Compton window of 93-125 keV (30%) were used. The set of scattered images was multiplied by a factor of 0.4 and subtracted from the primary images. The size of...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199611000-00009
更新日期:1996-11-01 00:00:00
abstract::High-grade astrocytoma represents the most common primary malignant brain tumour in the adult, and is associated with high morbidity and mortality rates. The aim of this study was to investigate the prognostic value of 99Tcm-hexamethylpropyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199312000-00002
更新日期:1993-12-01 00:00:00
abstract::This study surveyed practice in nuclear cardiology in the UK in 1994. A questionnaire was sent to 219 centres performing nuclear imaging asking for details of current practice in nuclear cardiology. Replies were received from 192 centres (88%). Activity in performance of myocardial perfusion imaging (MPI) and radionuc...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199804000-00004
更新日期:1998-04-01 00:00:00
abstract::The presence of distant metastases is the main prognostic factor in patients with breast cancer and has a significant influence in the choice of therapy. Therefore, chest X-ray, bone scintigraphy and ultrasound of the abdomen are performed to detect distant metastases at diagnosis and follow-up. Fluorodeoxyglucose pos...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200209000-00009
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:The present study evaluated the usefulness of postoperative fluorine-18 fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) in the management of olfactory neuroblastoma (ONB). MATERIALS AND METHODS:Ten patients (eight men and two women; mean age, 48.5 years) with histologically confirmed ONB who underwent ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000135
更新日期:2014-08-01 00:00:00
abstract::Ion-exchange resin beads, implanted into connective tissue, were used as the vehicle for the delivery of radiolabelled cations to determine the local distribution of lead, silver and cadmium in loose connective tissue. The system was devoid of systemic toxicity, permitted a predictable release, enabled location of rel...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198806000-00003
更新日期:1988-06-01 00:00:00
abstract::Salivary gland scintigraphy (SGS) is used to depict salivary gland dysfunction after radiotherapy (RT). The aim of this study was to investigate the utility of SGS combined with single photon emission computed tomography (SPECT). Twenty-one patients with a carcinoma of head and neck underwent SGS before and 1 month af...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200102000-00015
更新日期:2001-02-01 00:00:00
abstract::99mTc-bisphophonates bone scan, planar and single-photon emission computed tomography/computed tomography (SPECT/CT) modalities, is a commonly used technique that provides high sensitivity and specificity for detection of osseous metastases. However, besides bone metastases, SPECT/CT provides an accurate evaluation of...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001318
更新日期:2021-02-01 00:00:00
abstract::Published values of tissue weighting factors for adolescents and children derived from the life-span study of the atomic bomb survivors have been used to calculate the effective dose to patients aged 1, 5, 10 and 15 years undergoing a common paediatric procedure requiring one of the following radiopharmaceuticals: 99T...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199906000-00012
更新日期:1999-06-01 00:00:00
abstract:PURPOSE:The aim of the study was to assess the association between the burden of metastatic bone disease measured on F-NaF PET/computed tomography (CT) studies and the overall survival (OS) of patients with medullary thyroid cancer (MTC). METHODS:We retrospectively analyzed 31 patients with MTC who performed 18F-NaF P...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001175
更新日期:2020-05-01 00:00:00
abstract::The standard nuclear medicine textbooks describe the pyramidal lobe of the thyroid as arising from the upper part of the thyroid lobes. Anatomy and surgical texts however describe it as a thyroglossal tract remnant and state that it arises from the isthmus. Review of 150 thyroid scintigrams confirms that on scintigrap...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198403000-00006
更新日期:1984-03-01 00:00:00