Improved radiopharmaceutical based on 99mTc-Bombesin-folate for breast tumour imaging.

abstract：:High-grade astrocytoma represents the most common primary malignant brain tumour in the adult, and is associated with high morbidity and mortality rates. The aim of this study was to investigate the prognostic value of 99Tcm-hexamethylpropyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT...

journal_title：Nuclear medicine communications

authors： Rodrigues M,Fonseca AT,Salgado D,Vieira MR

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to compare quantitative ECG-gated single-photon emission computed tomography (SPECT) (QGS) and model-based ECG-gated single-photon emission computed tomography (MBGS) for determination of end-diastolic cardiac volume (EDV), end-systolic cardiac volume (ESV), and left ventricular...

journal_title：Nuclear medicine communications

authors： Khorsand A,Gyöngyösi M,Graf S,Zamini S,Schuster E,Sochor H,Porenta G

更新日期：2009-04-01 00:00:00

abstract：:First-pass radionuclide angiography, for the evaluation of ventricular function during peak physiological stress, requires the use of a low-energy point source for correction of motion artifacts. A design for the construction of a refillable 125I point source is presented. ...

journal_title：Nuclear medicine communications

authors： Hirsch JI,Fuhs BE,Tatum JL,Tatum TG

更新日期：1992-01-01 00:00:00

abstract：:Three ligand assays for TSH using monoclonal antibodies, an IRMA, an ELISA and a DELFIA were compared with a standard DAB RIA technique. The IRMA proved to be superior in respect to sensitivity, precision, reproducibility and practicality. The highest sensitivity yet, was achieved by DELFIA. IRMA, ELISA and DELFIA are...

journal_title：Nuclear medicine communications

authors： Böttger I,Pabst HW,Senekowitsch R,Kriegel H

更新日期：1985-04-01 00:00:00

abstract：PURPOSE:Renal ischemia-reperfusion injury (RIRI) may occur secondary to several reasons leading to renal failure. Coenzyme-Q10 (CoQ10) is a well-known antioxidant. However, the effects CoQ10 against RIRI have not been evaluated. Our aim was to evaluate protective effects of CoQ10 to renal ischemia-reperfusion by bioche...

journal_title：Nuclear medicine communications

authors： Akbulut A,Keseroglu BB,Koca G,Yuceturk CN,Ozgur BC,Surer H,Ogus E,Yumuşak N,Karakaya J,Korkmaz M

更新日期：2019-10-01 00:00:00

abstract：AIM:This study was carried out to compare the efficacy of Y, Lu, and combination of both radiotracers (tandem) peptide receptor radionuclide therapy (PRRT) in patients with inoperable and metastatic neuroendocrine tumors. MATERIALS AND METHODS:Systematic searches of PubMed and SciVerse Scopus databases were performed ...

journal_title：Nuclear medicine communications

authors： Dannoon SF,Alenezi SA,Elgazzar AH

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:The incidence of anal cancer is increasing in Western countries. Fluorine-18 fluorodeoxyglucose (F-FDG) PET-computed tomography (CT) is used in the assessment of anal cancer, but its routine use is not established. The aim of this study was to assess the value of F-FDG-PET-CT in staging and post-treatment as...

journal_title：Nuclear medicine communications

authors： Teagle AR,Gilbert DC,Jones JR,Burkill GJ,McKinna F,Dizdarevic S

更新日期：2016-10-01 00:00:00

abstract：:An increased uptake of bone-seeking radiopharmaceuticals into malignant bone lesions could further improve the diagnostic accuracy of routine bone scanning. The tracers used in clinical routine for bone scanning are methylene-diphosphonate (MDP), dicarboxypropane-diphosphonate (DPD) and ethylenediaminetetramethylene-p...

journal_title：Nuclear medicine communications

authors： Fueger BJ,Mitterhauser M,Wadsak W,Ofluoglu S,Traub T,Karanikas G,Dudczak R,Pirich C

更新日期：2004-04-01 00:00:00

abstract：:The main aim of this study was to investigate the role of N-(2,4,6 trimethyl-3-bromophenylcarbamoylmethyl) iminodiacetic acid (IDA; Mebrofenin) scintigraphy in follow-up assessments of the biliary system in patients with cystic fibrosis associated liver disease. Fourteen patients from a study published in 1996 were re...

journal_title：Nuclear medicine communications

authors： Foster JA,Ramsden WH,Conway SP,Taylor JM,Etherington C

更新日期：2002-07-01 00:00:00

abstract：AIM:To evaluate the biodistribution, internal radiation dosimetry and toxicity of the humanized MAb h-R3 labelled with Tc in humans. METHODS:Twenty-five patients with suspected epithelial-derived tumours were included in this study and divided into two groups: group I consisted of 10 patients who received 3 mg/1110 MB...

journal_title：Nuclear medicine communications

authors： Torres LA,Perera A,Batista JF,Hernández A,Crombet T,Ramos M,Neninger E,Pérez M,Sánchez EL,Romero S,Aguilar V,Coca MA,Iznaga-Escobar N

更新日期：2005-12-01 00:00:00

abstract：:The advent of PET instrumentation signaled the beginning of a new perspective in nuclear medicine diagnostic imaging. PET systems rely on several corrections that must be applied in order to establish accurate and reliable quantification. The inherent properties of PET detector architecture and the crystals themselves...

journal_title：Nuclear medicine communications

authors： Theodorakis L,Loudos G,Prassopoulos V,Kappas C,Tsougos I,Georgoulias P

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:Upon diagnosis, distant metastases are encountered in 21-50% of neuroendocrine tumours (NETs). However, few systemic treatment options are available for the well-differentiated NETs in the metastatic stage. Lu-DOTATATE is one of the most effective treatments in this limited patient group. We retrospectively inv...

journal_title：Nuclear medicine communications

authors： Demirci E,Kabasakal L,Toklu T,Ocak M,Şahin OE,Alan-Selcuk N,Araman A

更新日期：2018-08-01 00:00:00

abstract：:To assess the precision of gated equilibrium radioventriculography in measuring changes in left ventricular stroke volume (LVSV), we studied five dogs each with a chronically implanted electromagnetic flowmeter on the ascending aorta. Per cent changes in left ventricular stroke counts (LVSC) were compared to those in ...

journal_title：Nuclear medicine communications

authors： Valette H,Bourguignon MH,Apoil E,Moyse D,Wise RA,Buchanan JW,Wagner HN Jr,Syrota A

更新日期：1988-12-01 00:00:00

abstract：:Lymphoscintigraphy for sentinel node (SN) detection has been studied extensively in melanoma and breast cancer. In head and neck squamous cell carcinoma (HNSCC), however, experience in this field is relatively meagre. The purpose of this study was to document and evaluate lymphoscintigraphic findings in HNSCC patients...

journal_title：Nuclear medicine communications

authors： Nieuwenhuis EJ,Pijpers R,Castelijns JA,Snow GB

更新日期：2003-06-01 00:00:00

abstract：:We performed a prospective study to establish the optimal background correction algorithm for the determination of differential renal function (DRF), using 99Tc(m)-diethylenetriamine pentaacetate (99Tc(m)-DTPA) in the presence of unilateral hydronephrosis, with 24 h 99Tc(m)-dimercaptosuccinic acid (99Tc(m)-DMSA) uptak...

journal_title：Nuclear medicine communications

authors： Van de Wiele C,De Sadeleer C,Koole M,D'Asseler Y,Everaert K,Dierckx RA

更新日期：1998-03-01 00:00:00

abstract：:To make quantitative methods of nuclear medicine more available, four centres in Croatia participated in the national intercomparison study, following the materials and methods used in the previous international study organized by the International Atomic Energy Agency (IAEA). The study task was to calculate the activ...

journal_title：Nuclear medicine communications

authors： Grošev D,Gregov M,Wolfl MR,Krstonošić B,Debeljuh DD

更新日期：2018-08-01 00:00:00

abstract：:Measurements were made of the concentration of radioactivity in the breast milk of two patients: one following 100 MBq (2.7 mCi) 99Tcm-pertechnetate administration, and the other following administration of 550 MBq (15 mCi) 99Tcm-glucoheptonate. The fractional activity concentrations in the former case were about two ...

journal_title：Nuclear medicine communications

authors： Mountford PJ,Coakley AJ

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the diagnostic value of function volume/morphological volume ratio calculated from ventilation/perfusion single-photon emission computed tomography/computed tomography in distinguishing the lungs with bronchiolitis obliterans syndrome (BOS) from the lungs without this syndrome after lung transplan...

journal_title：Nuclear medicine communications

authors： Nakashima M,Shinya T,Oto T,Okawa T,Takeda Y

更新日期：2019-07-01 00:00:00

abstract：:This study combines the pharmacologically-induced penile erection (PIPE) technique with radionuclide phallography (RNP) for the non-invasive study of penile haemodynamic changes during erection. Penile erections produced by the intracavernosal injections of two different vasoactive drugs, prostaglandin E1 (PGE1) and p...

journal_title：Nuclear medicine communications

authors： Siraj QH,Bomanji J,Akhtar MA,Rana MH,Sadiq M,Ahmed M

更新日期：1990-06-01 00:00:00

abstract：:Radioactive tracer techniques using 131I- and 125I-insulin have been applied to study insulin metabolism. A simple method to label human insulin with 123I to a high specific activity is described. We have used this radiotracer to study insulin kinetics in vivo in normal subjects and in two groups of diabetic patients....

journal_title：Nuclear medicine communications

authors： Sinclair AJ,Signore A,Bomanji J,Britton KE,Pozzilli P,Gale EA

更新日期：1987-10-01 00:00:00

abstract：:In order to evaluate the utility of positron emission tomography (PET) with 18F-labelled deoxyglucose (FDG) for detection of pancreatic cancer 15 patients with pancreatic masses shown by computed tomography were investigated. Static PET scans covering an axial field of view of 15 cm were obtained 45 min after intraven...

journal_title：Nuclear medicine communications

authors： Bares R,Klever P,Hellwig D,Hauptmann S,Fass J,Hambuechen U,Zopp L,Mueller B,Buell U,Schumpelick V

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:Easy large-scale production, easy availability, cost-effectiveness, long half-life, and favorable radiation characteristics have made lutetium-177 (Lu) a preferred radionuclide for use in therapy. Lutetium-177-labeled stannous (Lu-Sn) colloid particles were formulated for application in radiosynovectomy, foll...

journal_title：Nuclear medicine communications

authors： Arora G,Singh M,Jha P,Tripathy S,Bal C,Mukherjee A,Shamim SA

更新日期：2017-07-01 00:00:00

abstract：:At present, it is difficult to distinguish between bacterial infections and sterile inflammatory processes using radiopharmaceuticals. This is so for a variety of reasons, including binding to bacteria with low affinity (e.g. infection) and binding to a specific micro-organism (e.g. radiolabelled monoclonal antibodies...

journal_title：Nuclear medicine communications

authors： Nibbering PH,Welling MM,van den Broek PJ,van Wyngaarden KE,Pauwels EK,Calame W

更新日期：1998-12-01 00:00:00

abstract：:First pass radionuclide angiocardiography (FPRNA) has gained increasing interest because of the development of new 99Tcm-labelled perfusion agents and of new 191Os/191Irm generator systems. The aim of the study was to evaluate the performance capacities of a small field of view single crystal digital gamma camera for ...

journal_title：Nuclear medicine communications

authors： Dobbeleir A,Franken PR,Ham HR,Brihaye C,Guillaume M,Knapp FF,Vandevivere J

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:Many studies have attempted to assess the significance of the use of the β(-)particle emitter praseodymium-142 ((142)Pr) in cancer treatment. As praseodymium oxide (Pr(2)O(3)) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable ...

journal_title：Nuclear medicine communications

authors： Bakht MK,Sadeghi M,Ahmadi SJ,Sadjadi SS,Tenreiro C

更新日期：2013-01-01 00:00:00

abstract：:Morphine sulfate has been used by several investigators in the cholescintigraphic diagnosis of acute cholecystitis. A review of the available literature indicates that morphine sulfate significantly reduces the total time required for the hepatobiliary examination, while retaining both high sensitivity (98.8%) and spe...

journal_title：Nuclear medicine communications

authors： Vasquez TE,Rimkus DS,Pretorius HT,Greenspan G

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:The current study was performed to evaluate the impact of Tc-EDDA-tricine-HYNIC-Tyr-octreotate in the differentiation of active from inactive pulmonary tuberculosis lesions. PATIENTS AND METHODS:Ten consecutive patients (six male and four female, age range 24-83 years) with proven pulmonary tuberculosis (wit...

journal_title：Nuclear medicine communications

authors： Ahmadihosseini H,Abedi J,Ghodsi Rad MA,Zakavi SR,Knoll P,Mirzaei S,Sadeghi R

更新日期：2014-12-01 00:00:00

abstract：:The aim of this study was to compare the extent and severity of wall motion abnormalities, perfusion and glucose metabolism, in recent myocardial infarction in patients with and without revascularization. Forty-nine patients were studied (82% men; mean age 58 years) by using echocardiography, 201Tl single photon emiss...

journal_title：Nuclear medicine communications

authors： González P,Massardo T,Coll C,Redondo F,Yovanovich J,Jofré J,Chamorro H,Humeres P,Sierralta P,Ramírez A,Kunstmann S,López H,Aramburú I,Brugère S

更新日期：2003-11-01 00:00:00

abstract：:In normal adults, the maintenance of phosphate balance involves the reabsorption of 85-90% of filtered phosphate by the proximal tubule. At a glomerular filtration rate (GFR) of 125 ml min-1 and a plasma phosphate concentration of 1.3 mmol l-1, the filtered phosphate is approximately 235 mmol day-1. Following intraven...

journal_title：Nuclear medicine communications

authors： Nair N,Mahadeo DS,Patel R

更新日期：1998-07-01 00:00:00

abstract：:Liver metastasis is a common consequence of colorectal carcinoma. Early and accurate detection of liver metastasis is crucial for a decision about partial hepatectomy, which is considered a standard and potentially curative therapy in such a setting. The presence of extrahepatic metastases will exclude surgical resect...

journal_title：Nuclear medicine communications

authors： Zhuang H,Sinha P,Pourdehnad M,Duarte PS,Yamamoto AJ,Alavi A

更新日期：2000-09-01 00:00:00