Abstract:
:Lymphoscintigraphy for sentinel node (SN) detection has been studied extensively in melanoma and breast cancer. In head and neck squamous cell carcinoma (HNSCC), however, experience in this field is relatively meagre. The purpose of this study was to document and evaluate lymphoscintigraphic findings in HNSCC patients. Eighty-two patients with clinical T1-T4 N0 SCC of the oral cavity or oropharynx received peritumoral injections of 25-75 MBq 99mTc-colloidal albumin (CA). Dynamic lymphoscintigraphy was performed in lateral projection for 20 min, followed by 2 min static imaging in anterior projection. In 26 patients, additional static images were obtained 2-6 h after injection of the tracer. In four of 82 patients, both early and late imaging revealed no tracer transport. In 78 of 82 patients, one (60), two (14) or three (4) SNs could be visualized, either by dynamic scintigraphy (73) or delayed static imaging (5). In 48 of 78 (62%) patients, the SN was visualized within the first minute of dynamic imaging. In particular, SNs of tumours of the mobile tongue were visualized within the first minute. No effect of T-stage or 99mTc-CA dose on the transport time of the tracer towards the SN was seen. The distribution of the SNs in the various levels of the neck relative to the primary tumour sites within the oral cavity was in concordance with the patterns of lymph node metastases reported traditionally for patients with SCC in the oral cavity. This study demonstrates the different variables affecting SN identification with lymphoscintigraphy using 99mTc-CA in HNSCC patients.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Nieuwenhuis EJ,Pijpers R,Castelijns JA,Snow GBdoi
10.1097/00006231-200306000-00006keywords:
subject
Has Abstractpub_date
2003-06-01 00:00:00pages
651-6issue
6eissn
0143-3636issn
1473-5628journal_volume
24pub_type
临床试验,杂志文章abstract:INTRODUCTION:In pediatric patients with abdominal Burkitt's lymphoma, the involvement of the gastrointestinal tract and abdominal lymph nodes are the main presenting feature of the disease. Chemotherapy is the main treatment modality and could be preceded by surgical excision of the abdominal masses. To achieve cure or...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328334fc14
更新日期:2010-03-01 00:00:00
abstract::There is a lack of systematic nephrographic studies on epidemic nephritis (EN). We studied 10 patients with EN using [99Tcm]MAG3 gamma camera nephrography and followed up 9 of them 22-68 days later when they had clinically recovered. Variables for renal clearance of [99Tcm]MAG3 and the retention of radioactivity in th...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199101000-00003
更新日期:1991-01-01 00:00:00
abstract::The carbon urea breath test ((14)C-UBT) is a noninvasive technique used to detect Helicobacter pylori infection in patients presenting with dyspeptic symptoms. The present study was undertaken to determine the efficacy of indigenously produced (14)C-UBT capsules by the Board of Radiation and Isotope Technology, India....
journal_title:Nuclear medicine communications
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abstract::Single photon emission computed tomography (SPECT) and positron emission tomography (PET) have advanced our understanding of the biological underpinnings of depression. There is, however, considerable variability in the literature. Depression is a complex disorder with marked heterogeneity in diagnosis and treatment. ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
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journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f8143b
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:To analyse the kinetic changes of uptake, washout and retention of Tc-sestamibi in order to evaluate the protective effects and possible mechanism of ischaemic preconditioning and adenosine preconditioning on myocardium injured by ischaemia/reperfusion. METHODS:Isolated ischaemia/reperfusion rabbit heart mod...
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pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f1781b
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journal_title:Nuclear medicine communications
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pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
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journal_title:Nuclear medicine communications
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1097/MNM.0b013e328360d8ec
更新日期:2013-06-01 00:00:00
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journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
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更新日期:2002-03-01 00:00:00
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journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
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更新日期:1995-07-01 00:00:00
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pub_type: 临床试验,杂志文章
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journal_title:Nuclear medicine communications
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更新日期:2014-12-01 00:00:00
abstract::INTRODUTION:: [Ga]Ga-prostate specific membrane antigen (PSMA)-11 showed a clear gain in sensitivity for lesion detection in the biological recurrence of prostate cancer as compared to the standard [F]fluorocholine radiopharmaceutical. To meet the strong demand for [Ga]Ga-PSMA-11, we aimed to optimize an automated rad...
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更新日期:2020-06-18 00:00:00
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journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
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更新日期:2009-06-01 00:00:00