Abstract:
OBJECTIVES:This survey was designed to assess the trends in the frequencies of nuclear medicine procedures in the UK and to determine their contributions to the annual collective effective dose to the UK population. The average activities administered by nuclear medicine departments were compared with guidance on diagnostic reference levels issued by the Administration of Radioactive Substances Advisory Committee. METHOD:The survey was carried out by e-mailing a questionnaire to every known nuclear medicine centre in the UK. RESULTS:The total number of procedures performed annually has increased by 36% over the last 10 years to a level of about 11 procedures per 1000 head of population in the financial year 2003-2004. Seventy-three per cent of all nuclear medicine administrations are for planar imaging, with single-photon emission computed tomography and positron emission tomography contributing 16% and 2%, respectively. Non-imaging diagnostic procedures represent 7% of all nuclear medicine administrations, and therapy 2%. Bone scans continue to be the most frequent procedure. The UK annual collective effective dose from diagnostic nuclear medicine is about 1600 man Sv, resulting in an annual per caput dose of nearly 0.03 mSv. Bone scans are the largest contributor to the collective dose, but myocardium scans are close behind. Planar imaging is responsible for 62% of the total collective effective dose from diagnostic nuclear medicine in the UK, with single-photon emission computed tomography, positron emission tomography and non-imaging contributing 33%, 5% and 0.3%, respectively. CONCLUSIONS:The practice of nuclear medicine is still expanding in the UK with single-photon emission computed tomography imaging of the myocardium rapidly approaching bone scans as the main contributor to population exposure. The activities administered for most procedures have remained substantially unchanged and adhere closely to those recommended by the Administration of Radioactive Substances Advisory Committee.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Hart D,Wall BFdoi
10.1097/01.mnm.0000184939.28994.f9keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
937-46issue
11eissn
0143-3636issn
1473-5628pii
00006231-200511000-00002journal_volume
26pub_type
杂志文章abstract:OBJECTIVE:The aim of this study was to investigate the diagnostic value of occipital lobe and posterior cingulate perfusion in predicting dopamine transporter imaging outcome using a quantitative measure of analysis. PATIENTS AND METHODS:In total, 99 patients with cognitive complaints who had undergone both technetium...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000750
更新日期:2017-12-01 00:00:00
abstract::Dual-isotope studies using 123I and 201Tl allow the assessment of sympathetic reinnervation in patients following heart transplantation. 123I-meta-iodobenzyl guanidine (123I-MIBG) serves as a tracer of the integrity of the sympathetic nervous system. 201Tl is used for landmarking to allow better delineation of the myo...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199508000-00009
更新日期:1995-08-01 00:00:00
abstract:INTRODUCTION:In pediatric patients with abdominal Burkitt's lymphoma, the involvement of the gastrointestinal tract and abdominal lymph nodes are the main presenting feature of the disease. Chemotherapy is the main treatment modality and could be preceded by surgical excision of the abdominal masses. To achieve cure or...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328334fc14
更新日期:2010-03-01 00:00:00
abstract::The objectives of this study were to measure semi-quantitatively uptake of 99Tcm-sestamibi (99Tcm-MIBI) by tumour tissue in patients with lung cancer and to investigate its relationship with clinical response to chemotherapy. 99Tcm-MIBI single photon emission tomography was performed at the time of diagnosis in 31 pat...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199711000-00013
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine the fraction of administered activity that was excreted and retained by a small cohort of patients who each received treatment with radium-223 dichloride (Ra). Ra is an α-emitting radionuclide that has been approved for use in the treatment of bone metastases that are sec...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000783
更新日期:2018-02-01 00:00:00
abstract::System upgrades are a constant feature of many highly technical specialties and are normally assumed to have a negligible effect on patient data. We report on the assessment of an upgrade made to a Norland XR-26 dual-energy X-ray absorptiometry (DXA) system. The upgraded version (2.3) consisted of new hip positioning ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199604000-00161
更新日期:1996-04-01 00:00:00
abstract::We evaluated the use of adenosine, dobutamine and arbutamine with (99m)Tc-tetrofosmin myocardial perfusion imaging. Forty patients under investigation for suspected coronary artery disease were recruited. Each had a resting scan and two separate stress scans on different days, in a randomized cross-over study. Resulta...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006231-200112000-00005
更新日期:2001-12-01 00:00:00
abstract::Technetium-99m-galactosyl human serum albumin (99mTc-GSA) is a radiopharmaceutical that binds to asialoglycoprotein receptors in the hepatocyte membrane; the level of 99mTc-GSA accumulation in the liver correlates well with the parameters of hepatic function tests. We hypothesized that the early blood kinetics of 99mT...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200107000-00008
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:Increasing evidence, primarily from animal studies and patients with compromised neurotransmitter systems, indicates a possibly important role for dopamine in modulating sleep. We therefore conducted this study to explore the relation between sleep and dopamine in healthy adults. METHODS:We used the Pittsburgh...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3280bad8b6
更新日期:2007-05-01 00:00:00
abstract:AIM:To investigate whether in lower extremity lymphoedema, lymph proteins enter blood before they do the thoracic duct. METHODS:Retrospective analysis of routine lymphoscintigraphy in 69 adults imaged at 5, 45 and 150 min following bilateral subcutaneous web space injection of Tc-nanocolloid was carried out. Regions o...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32835313d4
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To analyse the kinetic changes of uptake, washout and retention of Tc-sestamibi in order to evaluate the protective effects and possible mechanism of ischaemic preconditioning and adenosine preconditioning on myocardium injured by ischaemia/reperfusion. METHODS:Isolated ischaemia/reperfusion rabbit heart mod...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f1781b
更新日期:2007-11-01 00:00:00
abstract::Radioiodinated meta-iodobenzylguanidine (MIBG) is used routinely for imaging and targeted radiotherapy of tumours derived from the neural crest. Since active uptake of MIBG by the noradrenaline transporter (NAT) makes a greater contribution to total drug accumulation than passive uptake when MIBG is present at low con...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200005000-00005
更新日期:2000-05-01 00:00:00
abstract::Our aim was to determine whether the Ca2+ ion or cell membrane Ca2+ and Na+/Ca2+ ion transport systems are involved in maintaining the cell-associated activity of technetium-99m-hexakis-methoxy-isobutyl-isonitrile (99mTc-MIBI) and technetium-99m-ethylene-bis[bis(2-ethoxyethyl)phosphin] (99mTc-tetrofosmin) in tumour ce...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200302000-00008
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVES:(68)Ga-Dotatoc has become the PET radiopharmaceutical of choice for the diagnosis and treatment follow-up of neuroendocrine tumours. (68)Ga-Dotatoc is prepared on-site through a so-called magisterial preparation. The use of an appropriate buffer during the radiolabelling step is essential to maximize the lab...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32833acb99
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Single photon emission tomography (SPECT) of the lung is a well-established non-invasive technique for quantitative assessment of regional lung ventilation and perfusion distribution in children and in adults. However, its application in neonates as well as infants has been scarce because of several practica...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f25905
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the relevance of physiological In-octreotide uptake in the head of pancreas and to establish its imaging features in comparison with pathological uptake in patients with neuroendocrine tumors (NET). PATIENTS AND METHODS:We retrospectively reviewed all patients that underw...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000710
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:A mismatch between thallium-201 ((201)Tl) and iodine-123 ((123)I)-beta-methyl iodophenyl pentadecanoic acid (BMIPP) dual single-photon emission computed tomography (SPECT) reflects a dysfunctional but viable myocardium, such as stunned or hibernating myocardium, in patients with coronary artery disease (CAD)...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0000000000000228
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES AND METHODS:The recommended method for the measurement of radiochemical purity (RCP) of ¹¹¹In-labelled pentetreotide is thin-layer chromatography with a silica gel as the stationary phase and a 0.1 N sodium citrate solution (pH 5) as the mobile phase. According to the supplier's instructions, the mobile phas...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32834a7003
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:99mTc-depreotide (NeoTect) is a synthetic somatostatin analogue, which binds to somatostatin receptor (SSTR) subtypes 2, 3 and 5. Imaging patients with non-Hodgkin's lymphoma (NHL) using the somatostatin analogue In-pentetreotide (Octreoscan) has demonstrated the feasibility of identifying lymphoma sites wit...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/01.mnm.0000126628.01919.f9
更新日期:2004-08-01 00:00:00
abstract::To make quantitative methods of nuclear medicine more available, four centres in Croatia participated in the national intercomparison study, following the materials and methods used in the previous international study organized by the International Atomic Energy Agency (IAEA). The study task was to calculate the activ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,多中心研究
doi:10.1097/MNM.0000000000000877
更新日期:2018-08-01 00:00:00
abstract::To clarify the biological significance of [18F]fluorodeoxyglucose (18F-FDG) accumulation in patients with cancer, we assessed the relationships between 18F-FDG uptake and glucose transporter-1 (GLUT-1) expression and proliferation rate in human glioma and lung cancer. We obtained FDG PET images and measured standardiz...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200401000-00003
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To test the potential of a new reconstruction algorithm with Monte Carlo-based scatter correction in half-time myocardial perfusion single-photon emission computed tomography (SPECT). MATERIALS AND METHODS:The mathematical four-dimensional NURBS-based Cardiac-Torso phantom and the SIMIND Monte Carlo simulation...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328349c765
更新日期:2011-11-01 00:00:00
abstract::Pulmonary involvement in Behçet's disease (BD) is reported to indicate poor prognosis and high mortality. Our aim was to evaluate the pulmonary vascular status in BD. As 123I-meta-iodobenzylguanidine (123I-MIBG) shares the same uptake, storage and release mechanisms as norepinephrine, associated with the functional st...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200110000-00005
更新日期:2001-10-01 00:00:00
abstract:AIM:The first pathogenetic step in multiple myeloma is the emergence of a limited number of clonal plasma cells, clinically known as monoclonal gammopathy of undetermined significance (MGUS). Patients with MGUS do not have symptoms or end-organ damage but they do have a 1% annual risk of progression to multiple myeloma...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f5e5df
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:Our objective was to analyze the clinical management and the outcome of disease in differentiated thyroid carcinoma with initial and late distant metastases (M1). PATIENTS AND METHODS:Radioiodine (131I) therapy was applied in 77 differentiated thyroid carcinoma patients with M1 (31 patients with M1-initial a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32832cc2ab
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Radium-223 was a treatment approved for patients with metastatic castrate-resistant prostate cancer, symptomatic bone metastases and no-visceral metastases, in progression after at least two prior lines of systemic therapy, or ineligible for any available systemic treatment. The aim of this study was to prov...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001164
更新日期:2020-04-01 00:00:00
abstract::It is possible to obtain an estimate of the bone uptake of diphosphonates after 3 h (BU) on the basis of the difference between the dose administered and the sum of the component eliminated in the urine plus the component present in the extra-osseous volume of distribution. The results of this simple method have been ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199509000-00008
更新日期:1995-09-01 00:00:00
abstract:AIM:This study aims to assess the diagnostic role of F-FDG PET/computed tomography in primary staging and restaging of testicular cancer in comparison with contrast-enhanced diagnostic thoracic-abdominopelvic computed tomography. MATERIAL AND METHOD:Thirty-two consecutive male patients with testicular carcinoma (media...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001093
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:In this study, we evaluated and compared the level of myocardial ischaemia caused by cardiac syndrome X (CSX) and coronary slow flow (CSF) with single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI), and determined if changes in the level of myocardial ischaemia exist in CSF and ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001080
更新日期:2019-11-01 00:00:00
abstract::The British Nuclear Medicine Society has developed a process for the service-specific organizational audit of nuclear medicine departments. This process identified the need for a scheme suitable for the audit of the scientific and technical standards of a department providing such a service. This document has evolved ...
journal_title:Nuclear medicine communications
pub_type: 指南,杂志文章,实务指引
doi:10.1097/01.mnm.0000135041.46837.ca
更新日期:2004-08-01 00:00:00