A technique for the absolute quantification of 131I radiopharmaceuticals using SPECT.

abstract：OBJECTIVE:Large-scale clinical trials have demonstrated that beta blocker therapy improves the prognosis of dilated cardiomyopathy (DCM), but cardiac events sometimes occur even in patients showing favourable response to the therapy. In this study, the usefulness of meta-iodobenzyguanidine (MIBG) in predicting cardiac ...

journal_title：Nuclear medicine communications

authors： Fujimoto S,Inoue A,Hisatake S,Yamashina S,Yamashina H,Nakano H,Yamazaki J

更新日期：2005-02-01 00:00:00

abstract：AIM:99mTc-HL91 is a new hypoxia agent and can identify acutely ischaemic viable myocardium in a canine model using a standard gamma camera. The purpose of the study was to determine whether this tracer could be used to detect regional ischaemia in chronic ischaemic myocardium in a swine model. METHOD:Using a porcine m...

journal_title：Nuclear medicine communications

authors： Wu YW,Lee CM,Huang YH,Chou NK,Yen RF,Tzen KY,Huang PJ

更新日期：2005-12-01 00:00:00

abstract：:A gamma extremity monitoring system (GEMS) has been used to measure finger doses during radio-nuclide dispensing procedures. GEMS uses a small semi-conductor probe that can be attached to a finger from which a continuous read-out can be obtained that is related to dose rate. The pattern of dose accumulation can be ana...

journal_title：Nuclear medicine communications

authors： Montgomery A,Anstee DE,Martin CJ,Hilditch TE

更新日期：1999-02-01 00:00:00

abstract：:The aim of this study was to develop a quantitative method to assess viable tumour based on post-operative 201Tl single photon emission tomography (SPET). We studied 15 patients with histologically defined highly malignant gliomas in the post-operative phase before initiation of adjuvant treatment. A 201Tl index was c...

journal_title：Nuclear medicine communications

authors： Källén K,Geijer B,Andersson AM,Holtås S,Ryding E,Rosén I

更新日期：1999-09-01 00:00:00

abstract：:Since the appearance of superficial tissue is often an unreliable indicator of deep tissue viability in cases of frostbite, radionuclide scintigraphy with 99Tcm-disodium oxidronate (HDP) was used to assess changes in tissue viability after experimental freezing and thawing of the rabbit ear. One shaved ear, left or ri...

journal_title：Nuclear medicine communications

authors： Junila J,Torniainen P,Kaarela O,Kairaluoma MI,Waris T

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:In studies of the distribution of lung function, the image quality of lung single photon emission computed tomography (SPECT) is important and one factor influencing it is the reconstruction algorithm. AIM:To systematically evaluate ordered subsets expectation maximization (OSEM) and compare it with filtere...

journal_title：Nuclear medicine communications

authors： Norberg P,Bake B,Jacobsson L,Carlsson GA,Gustafsson A

更新日期：2007-12-01 00:00:00

abstract：:A new radiopharmaceutical, 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HM-PAO) is described. This agent displays considerable promise for imaging cerebral blood flow. In studies in rats and one human volunteer, 99Tcm-HM-PAO demonstrates good brain uptake, prolonged retention of activity in the brain, and slow regional...

journal_title：Nuclear medicine communications

authors： Holmes RA,Chaplin SB,Royston KG,Hoffman TJ,Volkert WA,Nowotnik DP,Canning LR,Cumming SA,Harrison RC,Higley B

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:The current study was performed to evaluate the impact of Tc-EDDA-tricine-HYNIC-Tyr-octreotate in the differentiation of active from inactive pulmonary tuberculosis lesions. PATIENTS AND METHODS:Ten consecutive patients (six male and four female, age range 24-83 years) with proven pulmonary tuberculosis (wit...

journal_title：Nuclear medicine communications

authors： Ahmadihosseini H,Abedi J,Ghodsi Rad MA,Zakavi SR,Knoll P,Mirzaei S,Sadeghi R

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The liver is the most frequent metastatic site from colorectal cancer and about 20% of these patients are treated by surgical resection. However, the 5-year disease-free survival (DFS) following resection is only about 25% and 5-year overall survival (OS) about 38%. The aim of the study was to evaluate the ab...

journal_title：Nuclear medicine communications

authors： Grut H,Stern NM,Dueland S,Labori KJ,Dormagen JB,Schulz A

更新日期：2020-09-01 00:00:00

abstract：:The method described by Weisner et al. for stabilizing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) with cobalt chloride hexahydrate solution is the most promising developed to date. The aim of our work was to study the behaviour of cobalt during the labelling of leukocytes with 99Tcm-HMPAO stabilized in vitro ...

journal_title：Nuclear medicine communications

authors： Prangere T,Bowden AD,Beauchat V,Caulier MT,Ziegels P,Huglo D,Pickett RD,Steinling M

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...

journal_title：Nuclear medicine communications

authors： Cohen JB,Kalinyak JE,McDougall IR

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:To investigate the accuracy of different interpretative approaches and to evaluate the management implications of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in cutaneous malignant melanoma. METHODS:We retrospectively identified 60 consecutive patients who underwent 76 PET/...

journal_title：Nuclear medicine communications

authors： Falk MS,Truitt AK,Coakley FV,Kashani-Sabet M,Hawkins RA,Franc B

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:There is evidence that the status of human papilloma virus subtype 16 (HPV-p16) alters the prognosis of patients with oropharyngeal squamous cell cancer (OSCC). We sought to establish whether there is a relationship between HPV-p16 status and 18F-FDG uptake in the prognosis of OSCC. MATERIALS AND METHODS:Patie...

journal_title：Nuclear medicine communications

authors： Huang YT,Ravi Kumar AS,Bhuta S

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the clinical role of technetium-99m pertechnetate (Tc-99m) imaging in thyroidectomized differentiated thyroid cancer patients immediately before radioiodine-131 (I-131) treatment (Tx). PATIENT AND METHODS:Eighty-six consecutive post-total-thyroidectomy patients (15 men, 71...

journal_title：Nuclear medicine communications

authors： Tsai CJ,Cheng CY,Shen DH,Kuo SJ,Wang LY,Lee CH,Wang JJ,Chang MC,Huang WS

更新日期：2016-02-01 00:00:00

abstract：:Many materials and types of implant have been used to achieve a cosmetic effect and prosthesis motility in the anophthalmic socket. Hydroxyapatite remains the implant material of choice for producing the most natural prosthesis motility while porous polyethylene shows promising characteristics as another useful materi...

journal_title：Nuclear medicine communications

authors： Pan MH,Wu YW,Yen RF,Tzen KY,Liao SL,Kao CH

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To assess standardized uptake value (SUV) measurement uncertainty (MU) of lung cancer lesions with uptake greater than mediastinum but less than or equal to the liver and that of the mediastinum blood pool, and to compare lesion SUV with mediastinum SUV by assessing MU of their ratio. PATIENTS AND METHODS:Dy...

journal_title：Nuclear medicine communications

authors： Laffon E,Milpied N,Marthan R

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Respiratory gated perfusion single photon emission computed tomography (SPECT) was applied to reduce respiratory lung motion effects and to reliably assess perfusion impairment in various lung diseases. METHODS:After injection of 259 MBq of 99mTc macroaggretated albumin (99mTc-MAA), gating was performed using ...

journal_title：Nuclear medicine communications

authors： Suga K,Kawakami Y,Zaki M,Yamashita T,Matsumoto T,Matsunaga N

更新日期：2004-02-01 00:00:00

abstract：:Our aim was to determine whether the Ca2+ ion or cell membrane Ca2+ and Na+/Ca2+ ion transport systems are involved in maintaining the cell-associated activity of technetium-99m-hexakis-methoxy-isobutyl-isonitrile (99mTc-MIBI) and technetium-99m-ethylene-bis[bis(2-ethoxyethyl)phosphin] (99mTc-tetrofosmin) in tumour ce...

journal_title：Nuclear medicine communications

authors： Arbab AS,Ueki J,Koizumi K,Araki T

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:PET/computed tomography (CT) imaging with the sodium-(F)-fluoride/2-(F)-fluoro-2-deoxy-D-glucose (F-NaF/F-FDG) cocktail has been proposed for patients with osseous metastases. This work aimed to optimize the cocktail composition for patients with metastatic castration-resistant prostate cancer (mCRPC). MATE...

journal_title：Nuclear medicine communications

authors： Simoncic U,Perlman S,Liu G,Jeraj R

更新日期：2015-12-01 00:00:00

abstract：:In normal adults, the maintenance of phosphate balance involves the reabsorption of 85-90% of filtered phosphate by the proximal tubule. At a glomerular filtration rate (GFR) of 125 ml min-1 and a plasma phosphate concentration of 1.3 mmol l-1, the filtered phosphate is approximately 235 mmol day-1. Following intraven...

journal_title：Nuclear medicine communications

authors： Nair N,Mahadeo DS,Patel R

更新日期：1998-07-01 00:00:00

abstract：:We have developed a new method to replace the conventional method of quantitatively measuring cerebral blood flow (CBF), in which octanol-extracted radioactivity counts are measured in continuous arterial blood samples. With the new method, the whole-brain time-activity curves early after the intravenous injection of ...

journal_title：Nuclear medicine communications

authors： Fujioka H,Murase K,Inoue T,Ishimaru Y,Akamune A,Yamamoto Y,Ikezoe J

更新日期：1998-06-01 00:00:00

abstract：:Although several hypotheses have been suggested regarding the accumulation of 99Tc(m)-sestamibi in tumours, the exact uptake mechanism is still a matter of discussion. We investigated ultrastructural cell type of thyroid tumours by electron microscopy (EM) and compared them with uptake of 99Tc(m)-sestamibi. Thyroid sc...

journal_title：Nuclear medicine communications

authors： Sarikaya A,Huseyinova G,Irfanoğlu ME,Erkmen N,Cermik TF,Berkarda S

更新日期：2001-01-01 00:00:00

abstract：:A significant reduction of cardiac 123I-meta-iodobenzylguanidine (MIBG) accumulation has been reported in patients with idiopathic Parkinson's disease. However, it is unclear whether this reduction in cardiac sympathetic nerve is caused primarily or secondarily to the degeneration of sympathetic nerve centres which oc...

journal_title：Nuclear medicine communications

authors： Takatsu H,Wada H,Maekawa N,Takemura M,Saito K,Fujiwara H

更新日期：2002-02-01 00:00:00

abstract：:We studied 20 patients aged 46-69 years (mean 57 years) undergoing long-term haemodialysis (HD) and 20 age- and sex-matched controls with single photon emission tomography (SPET) and 99Tcm-hexamethyl-propyleneamine-oxime to look for regional abnormalities in cerebral blood flow (CBF) and their relation to cognitive dy...

journal_title：Nuclear medicine communications

authors： Fazekas G,Fazekas F,Schmidt R,Flooh E,Valetitsch H,Kapeller P,Krejs GJ

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:We retrospectively investigated the value of dynamic Tc-diisopropyl-iminodiacetic acid hepatobiliary scintigraphy (HBS) in discriminating postsurgical complications following liver transplantation (LT). METHODS:Dynamic HBS was performed for suspected post-LT complications in 201 cases. Hepatic uptake and exc...

journal_title：Nuclear medicine communications

authors： Lee JY,Hu W,Lee KH,Kwon CH,Lee EJ,Choi JY,Kim BT

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...

journal_title：Nuclear medicine communications

authors： Zhang Y,He J,Liu G,Venderheyden JL,Gupta S,Rusckowski M,Hnatowich DJ

更新日期：2004-11-01 00:00:00

abstract：INTRODUCTION:In the present study, (99m)Tc-radiolabelled E-selectin binding peptide ((99m)Tc-IMP-178) was investigated for its potential to image acute pyogenic osteomyelitis in a new animal model. Intraindividual comparisons were performed using an irrelevant peptide ((99m)Tc-IMP-100) to demonstrate specificity. METH...

journal_title：Nuclear medicine communications

authors： Gratz S,Béhé M,Boerman OC,Kunze E,Schulz H,Eiffert H,O'Reilly T,Behr TM,Angerstein C,Nebendahl K,Kauer F,Becker W

更新日期：2001-09-01 00:00:00

abstract：:Dynamic penile scintigraphy was performed using 99Tcm-labelled autologous erythrocytes in five normally potent volunteers and 22 patients with erectile dysfunction including 11 patients with psychogenic and 11 patients with vasculogenic impotence (four arteriogenic, three venogenic, three arteriogenic and venogenic, o...

journal_title：Nuclear medicine communications

authors： Siraj QH,Hilson AJ,Bomanji J,Ahmed M

更新日期：1993-11-01 00:00:00

abstract：:Salivary gland scintigraphy (SGS) is used to depict salivary gland dysfunction after radiotherapy (RT). The aim of this study was to investigate the utility of SGS combined with single photon emission computed tomography (SPECT). Twenty-one patients with a carcinoma of head and neck underwent SGS before and 1 month af...

journal_title：Nuclear medicine communications

authors： van Acker F,Flamen P,Lambin P,Maes A,Kutcher GJ,Weltens C,Hermans R,Baetens J,Dupont P,Rijnders A,Maes A,van den Bogaert W,Mortelmans L

更新日期：2001-02-01 00:00:00

abstract：:The British Nuclear Medicine Society has developed a process for the service-specific organizational audit of nuclear medicine departments. This process identified the need for a scheme suitable for the audit of the scientific and technical standards of a department providing such a service. This document has evolved ...

journal_title：Nuclear medicine communications

authors： Jarritt PH,Perkins AC,Woods SD,British Nuclear Medicine Society.

更新日期：2004-08-01 00:00:00