Abstract:
:Dynamic penile scintigraphy was performed using 99Tcm-labelled autologous erythrocytes in five normally potent volunteers and 22 patients with erectile dysfunction including 11 patients with psychogenic and 11 patients with vasculogenic impotence (four arteriogenic, three venogenic, three arteriogenic and venogenic, one arteriogenic and neurogenic). Penile radioactivity changes in the flaccid state were monitored by a gamma camera for 60 min after injection of the radionuclide. The penile time-activity curves of the normal controls characteristically showed secondary pulses of increased activity of variable amplitude, duration and frequency, consistent with phasic increase in penile blood pool. This normal rhythmic pattern was impaired in patients with penile arterial insufficiency whereas a blunted pattern was seen in most patients with functional impotence as well as in patients with nonarteriogenic organic impotence with a psychological overlay. This study provides new insights into the flaccid penile circulatory physiology, which may contribute to our understanding of the pathophysiology of erectile dysfunction. In arteriogenic subjects, the impaired response may be attributable to an inadequacy of penile arterial inflow as well as secondarily due to the resultant sinusoidal dysfunction subsequent to penile ultrastructural damage due to an altered nutritive environment. Increased adrenergic activity in patients with psychogenic impotence may be responsible for the observed deviation from the normal pattern.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Siraj QH,Hilson AJ,Bomanji J,Ahmed Mdoi
10.1097/00006231-199311000-00007subject
Has Abstractpub_date
1993-11-01 00:00:00pages
976-82issue
11eissn
0143-3636issn
1473-5628journal_volume
14pub_type
杂志文章abstract:OBJECTIVES:The objective of this study was to determine the predictive value of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) to a positive fluorine-18 fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (CT) result in patients with inflammation of unknown origin and fever of unknown origin. PAT...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000300
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVES:Differential renal function (DRF) calculation with 99mTc-diethylenetriamine-pentaacetic acid (DTPA) or mercaptoacetyltriglycine (MAG3) is gaining clinical importance in the evaluation of patients with ureteropelvic junction obstruction with hydronephrosis (HN). Although many decisions regarding surgery are b...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32830978af
更新日期:2008-11-01 00:00:00
abstract::Captopril renography is used for the non-invasive diagnosis of renovascular hypertension, but suffers from the drawbacks of lower sensitivity and false-positive tests due to a fall in blood pressure. Aspirin renography has been proposed as a useful test for evaluation of unilateral renal artery stenoses of moderate de...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200004000-00006
更新日期:2000-04-01 00:00:00
abstract::The results of scintigraphy in 29 patients with Cushing's syndrome were evaluated. It was possible to separate bilateral hyperplasia from unilateral abnormality. In cases of unilateral abnormality correct localization of the tumour was accomplished and it was possible to visualize adrenocortical carcinoma. The many ad...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198501000-00005
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200504000-00003
更新日期:2005-04-01 00:00:00
abstract::We performed a prospective study to establish the optimal background correction algorithm for the determination of differential renal function (DRF), using 99Tc(m)-diethylenetriamine pentaacetate (99Tc(m)-DTPA) in the presence of unilateral hydronephrosis, with 24 h 99Tc(m)-dimercaptosuccinic acid (99Tc(m)-DMSA) uptak...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199803000-00009
更新日期:1998-03-01 00:00:00
abstract::Many materials and types of implant have been used to achieve a cosmetic effect and prosthesis motility in the anophthalmic socket. Hydroxyapatite remains the implant material of choice for producing the most natural prosthesis motility while porous polyethylene shows promising characteristics as another useful materi...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200312000-00006
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVE:Collecting positron emission tomography data in three-dimensional (3D) mode may potentially allow reduction of the tracer dose and/or the acquisition time without compromising image quality thereby making the procedure more patient-friendly and cost effective. The objective of our study was to compare VUE Poi...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/mnm.0b013e328315a22a
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:The value of gated single-photon emission computed tomography technetium-99m methoxyisobutylisonitrile (gated SPECT (99m)Tc-MIBI) in children is not yet established probably because gated SPECT (99m)Tc-MIBI has rarely been used in pediatric clinical and research studies. The purpose of this study was to eval...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283295622
更新日期:2010-01-01 00:00:00
abstract::In the presence of abnormal fluid collection (e.g. ascites), the measurement of glomerular filtration rate (GFR) based on a small number (1-4) of plasma samples fails. This study investigated how a few samples will allow adequate characterization of plasma clearance to give a robust and accurate GFR measurement. A tot...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328356fb6d
更新日期:2012-09-01 00:00:00
abstract::Changes in regional ejection fraction (rEF) of the interventricular septum following coronary artery bypass graft (CABG) surgery were examined using first-pass radionuclide ventriculography (RNVG) in patients without objective evidence of postoperative myocardial infarction (MI). One hundred and one patients had pre- ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVE:Our objective was to analyze the clinical management and the outcome of disease in differentiated thyroid carcinoma with initial and late distant metastases (M1). PATIENTS AND METHODS:Radioiodine (131I) therapy was applied in 77 differentiated thyroid carcinoma patients with M1 (31 patients with M1-initial a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32832cc2ab
更新日期:2009-07-01 00:00:00
abstract::(99m)Tc dimercaptosuccinic acid (DMSA) renal scans can provide accurate diagnosis of acute pyelonephritis, its sequelae (renal scars) and differential renal function (DRF). The purposes of this retrospective study were (1) to assess the relationship between DRF obtained during acute pyelonephritis and at follow-up, an...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200210000-00011
更新日期:2002-10-01 00:00:00
abstract::The time course of thyroglobulin (Tg) was monitored in patients with differentiated thyroid carcinoma after ablative therapy (thyroidectomy + 131I-treatment) with particular respect to endogeneous antibodies (Tg-ABs). In 232 patients (196 without Tg-ABs, 36 with Tg-ABs at the time of treatment) a sensitivity of 88% (a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198405000-00003
更新日期:1984-05-01 00:00:00
abstract::A technique is described for the quantification of the three-dimensional distribution of 131I radiopharmaceuticals using single photon emission computed tomography (SPECT). A theoretical discussion of the problems of scatter and septal penetration in 131I SPECT is presented. The correction of these effects using the g...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199306000-00014
更新日期:1993-06-01 00:00:00
abstract::This study combines the pharmacologically-induced penile erection (PIPE) technique with radionuclide phallography (RNP) for the non-invasive study of penile haemodynamic changes during erection. Penile erections produced by the intracavernosal injections of two different vasoactive drugs, prostaglandin E1 (PGE1) and p...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199006000-00007
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200411000-00008
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:Ewing sarcoma breakpoint region 1 (EWSR1) translocation-negative tumors represent a minor portion of small round cell tumors consistent with Ewing sarcoma morphology. The purpose of this study was to differentiate EWSR1 translocation-positive tumors from EWSR1 translocation-negative tumors using PET-computed...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001031
更新日期:2019-08-01 00:00:00
abstract::Many common PET segmentation methods for malignant lesions use surrounding background activity as a reference. To date, background has to be measured by drawing a second volume of interest (VOI) in nearby, undiseased tissue. This is time consuming as two VOIs have to be determined for each lesion. The aim of our study...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000045
更新日期:2014-03-01 00:00:00
abstract::Fifty-six patients with hypertrophic cardiomyopathy who had echocardiography and cardiac catheterization were studied. Eleven (18%) of 56 patients had right ventricular (RV) thallium-201 visualization at resting scan. RV thallium-201 visualization was observed in the apex or lower half of the RV free wall, which was q...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Screening for radioactive material at borders may become more widely introduced in order to prevent illegal transport. All the alarms at Vienna airport so far have been due to recent applications of radionuclides for medical reasons. METHODS:We report a patient who unexpectedly experienced this problem afte...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200501000-00011
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the diagnostic value of function volume/morphological volume ratio calculated from ventilation/perfusion single-photon emission computed tomography/computed tomography in distinguishing the lungs with bronchiolitis obliterans syndrome (BOS) from the lungs without this syndrome after lung transplan...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001021
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:The diagnosis of painful hip without remarkable radiographic findings is still challenging. In recent years, femoroacetabular impingement (FAI) has been recognized as an important cause of painful hip. The hypothesis of this study was that local bone turnover may be accelerated in painful hip, especially in F...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0000000000000456
更新日期:2016-04-01 00:00:00
abstract::The ability of 99Tcm-methoxyisobutylisonitrile (MIBI) single photon emission tomography (SPET) to detect myocardial ischaemia and necrosis was assessed in 56 patients (45 male, 11 female, aged 55 +/- 5 years), with clinically recognized ischaemic heart disease (IHD). All underwent coronary angiography (CA) and left ve...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199212000-00004
更新日期:1992-12-01 00:00:00
abstract:PURPOSE:The regions of significant correlation between cerebral hypoperfusion and neuropsychological assessment scores were evaluated using (99m)Tc-HMPAO SPECT in patients with mild cognitive impairment (MCI) on the basis of its three subtypes, namely, single-domain amnestic MCI (aMCI-s), multiple-domain amnestic MCI (...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32835587f8
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:In-vivo quantitative cerebral blood flow (CBF) measurement using positron emission tomography (PET) has typically employed invasive arterial blood sampling procedure to determine the arterial input function (AIF). The present study was performed to provide a non-invasive quantitative CBF measurement technique...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200510000-00009
更新日期:2005-10-01 00:00:00
abstract::In an effort to develop new, clinically useful 99Tcm-diaminodithiol (99Tcm-DADT) complexes for the evaluation of regional cerebral perfusion, basic diaminodithiols (DADT-TM, DADT-HM and DADT-MHM) and three diaminodithiol ligands functionalized with p-iodophenethyl (DADT-IPE), N-ethyl-p-fluorophenethyl amine (DADT-EFPE...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199112000-00007
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to evaluate the role of F-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (CT) in the early postoperative staging of breast cancer and to document (18)F-FDG PET/CT-based stage alterations and any subsequent impact on management. MATERIALS AND METHODS:Between January 2009 and ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328360d8ec
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Large cell pulmonary neuroendocrine carcinoma (LCNEC) is a poorly differentiated and high-grade neoplasm. It is positioned between an atypical carcinoid and small cell neuroendocrine carcinoma of the lung in a distinct family of pulmonary neuroendocrine tumors. The aim of our study was to detect somatostatin ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32834508b3
更新日期:2011-06-01 00:00:00
abstract:INTRODUCTION:It has been suggested that renal retention function can be estimated by differentiation of the Patlak-Rutland plot. AIM:To evaluate the error resulting from this method. METHODS:A total of 5800 renograms were generated by convolving real input functions with artificial retention functions. Ten bi-exponen...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200405000-00012
更新日期:2004-05-01 00:00:00