Abstract:
:The time course of thyroglobulin (Tg) was monitored in patients with differentiated thyroid carcinoma after ablative therapy (thyroidectomy + 131I-treatment) with particular respect to endogeneous antibodies (Tg-ABs). In 232 patients (196 without Tg-ABs, 36 with Tg-ABs at the time of treatment) a sensitivity of 88% (accuracy, 93%) was found at the first follow up examination. Twelve months later, 11 of the 36 patients did not present Tg-ABs, therefore, the sensitivity increased to 91% (accuracy, 94%) at that time. It is expected that the determination of Tg can also be employed in patients presenting ABs initially.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Moser E,Braun S,Kirsch CM,Kleinhans E,Buell Udoi
10.1097/00006231-198405000-00003subject
Has Abstractpub_date
1984-05-01 00:00:00pages
317-21issue
5eissn
0143-3636issn
1473-5628journal_volume
5pub_type
杂志文章abstract::Radiolabeled immunotherapy (RIT) is becoming a significant step forward in the treatment management of non-Hodgkin's lymphoma (NHL). In this state-of-the-art review article, general details, practical and health economic aspects, and next steps of RIT in NHL are reviewed from the existing literature and latest abstrac...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/MNM.0b013e328313e565
更新日期:2009-01-01 00:00:00
abstract:AIM AND PURPOSE:Radionuclide imaging of the kidneys using dimercaptosuccinic acid chelate labeled with technetium-99m (Tc-DMSA) is a well-established method for evaluating the extent of kidney parenchymal involvement in the scenario of urinary tract infection and for the estimation of the functional renal mass. We have...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283396073
更新日期:2010-07-01 00:00:00
abstract::Although several hypotheses have been suggested regarding the accumulation of 99Tc(m)-sestamibi in tumours, the exact uptake mechanism is still a matter of discussion. We investigated ultrastructural cell type of thyroid tumours by electron microscopy (EM) and compared them with uptake of 99Tc(m)-sestamibi. Thyroid sc...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200101000-00006
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:The recent development of mixed ligand complexes using a 99mTc tricarbonyl synthon has prompted us to revisit the first generation product, 99mTc-t-butyl isonitrile (TBI), for possible myocardial imaging after modification of the 99mTc core to a mixed ligand core of carbonyl and t-butyl isonitrile. The easy a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200502000-00013
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND AND AIM:Researchers find that monitoring the differentiation of implanted cells in vivo is difficult. This study was designed to show that it is possible to track the efficacy of transplanted human retinal pigment epithelial cells (RPE cells) in a rat model of Parkinson's disease by using positron emission t...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f5d291
更新日期:2008-05-01 00:00:00
abstract:BACKROUND:Human tumors show intrinsic heterogeneity and changes in phenotype during disease progression, which implies different expression levels of cell surface receptors. The research on new heterodimeric lutetium-177 (Lu)-radiopharmaceuticals interacting with two different targets on tumor cells is a strategy for i...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000966
更新日期:2019-03-01 00:00:00
abstract::The aim of this study was to compare the extent and severity of wall motion abnormalities, perfusion and glucose metabolism, in recent myocardial infarction in patients with and without revascularization. Forty-nine patients were studied (82% men; mean age 58 years) by using echocardiography, 201Tl single photon emiss...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200311000-00006
更新日期:2003-11-01 00:00:00
abstract::The method described by Weisner et al. for stabilizing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) with cobalt chloride hexahydrate solution is the most promising developed to date. The aim of our work was to study the behaviour of cobalt during the labelling of leukocytes with 99Tcm-HMPAO stabilized in vitro ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199703000-00010
更新日期:1997-03-01 00:00:00
abstract::Patients infected with the human immunodeficiency virus (HIV) suffer from serious and life-threatening infections. These patients often present with pyrexia but without localizing signs. Despite its high sensitivity in identifying focal infection 67Ga citrate scintigraphy lacks specificity; lymphoma and solid tumours ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199107000-00003
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Single photon emission tomography (SPECT) of the lung is a well-established non-invasive technique for quantitative assessment of regional lung ventilation and perfusion distribution in children and in adults. However, its application in neonates as well as infants has been scarce because of several practica...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f25905
更新日期:2008-02-01 00:00:00
abstract::In the presence of abnormal fluid collection (e.g. ascites), the measurement of glomerular filtration rate (GFR) based on a small number (1-4) of plasma samples fails. This study investigated how a few samples will allow adequate characterization of plasma clearance to give a robust and accurate GFR measurement. A tot...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328356fb6d
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:Postprandial insulin secretion causes extensive skeletal muscle accumulation (ESMA) of fluorine-18 fluorodeoxyglucose (FDG), which adversely affects visual interpretation of FDG-PET/CT. We investigated factors related to ESMA despite a fast of at least 4 h. METHODS:A total of 3595 patients underwent FDG-PET...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328352290f
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:In our study, tumor heterogeneity was evaluated using the parameters skewness and kurtosis on pretreatment Ga-68 DOTA-TATE PET/CT to assess therapy responses of lesions in patients with gastroenteropancreatic neuroendocrine tumors (GEP NETs) treated with peptide receptor radionuclide therapy (PRRT). METHOD:We ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001231
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the diagnostic value of fluorodeoxyglucose-18 (FDG)-PET/computed tomography (CT) and MRI parameters in determining the molecular subtypes of invasive breast cancer. METHODS:Data from 55 primary invasive breast cancer masses in 51 female patients who underwent pre-treat...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001220
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Echocardiography plays a central role in the diagnosis of hypertrophic cardiomyopathy (HCM). However, apical involvement of HCM may be missed because of foreshortening and inadequate clinical suspicion. These patients may be referred for single-photon emission computed tomography imaging. METHODS:We present...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328334fc41
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:Neurokinin 1 (NK1) receptors have been implicated in depression, anxiety, and pain perception. Recently, it was shown that, in the human brain, a specific NK1 receptor-related signal was obtained with the novel radioligand, [¹¹C]R116301, using positron emission tomography. The purpose of this study was to evalu...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e328347e96f
更新日期:2011-10-01 00:00:00
abstract::Using platelet scintigraphy to evaluate early thrombogenicity, we examined 39 new vascular accesses 4 weeks and 3 months after surgery. We found a significant association between platelet deposition and Doppler flow (P < 0.01) and blood pressure (P < 0.01). Compared with arteriovenous fistulae, prosthetic grafts showe...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199905000-00008
更新日期:1999-05-01 00:00:00
abstract::The purpose of this study was to demonstrate the accumulation of 99Tcm-glutathione (GSH) in experimental abscesses. The biodistribution of 99Tcm-GSH was determined in mice with turpentine-induced abscesses in comparison with 99Tcm-human immunoglobulin (HIG) at 1, 3, 6 and 24 h. Arthritis was induced by intra-articular...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199407000-00007
更新日期:1994-07-01 00:00:00
abstract::201Tl myocardial perfusion single photon emission tomography (SPET) with pharmacological coronary vasodilatation using adenosine is now often used in the investigation of a patient with ischaemic heart disease (IHD). In this study, we present data from two groups of patients. Group A (n = 40) experienced 201Tl SPET wi...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-199408000-00003
更新日期:1994-08-01 00:00:00
abstract::Bone scintigraphy has been shown to be sensitive in determining bone involvement in patients with malignancy, but it does not allow the assessment of bone marrow lesions in early disease. The aim of this study was to detect bone marrow invasion using 99Tcm-labelled monoclonal antigranulocyte antibody (AgMoAb) in patie...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-199710000-00013
更新日期:1997-10-01 00:00:00
abstract:AIMS:Peptide receptor radionuclide therapy (PRRT) has been shown to be useful in inoperable/metastatic medullary thyroid carcinoma (MTC). However, the role of concomitant PRRT and low-dose capecitabine therapy has not yet been studied in these patients. This study was conducted to evaluate the efficacy and safety of th...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001205
更新日期:2020-07-01 00:00:00
abstract::Four methods of calculating the activity of 99Tcm-hexamethylpropyleneamine oxime to be administered in cerebral blood flow investigations of children were evaluated in patient studies. Three of the methods were based on the size of the child. We also constructed a theoretical dosage model based on physiological data a...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199605000-00012
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVES:This work aims to assess whether the biochemical response of radium-223-dichloride treatment can be predicted based on the pretherapy bone scan, and consequently if bone scan index (BSI) and maximum lesion intensity have a place as alternatives or as complements to extent of bone disease (EOBD) scoring in pr...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001005
更新日期:2019-06-01 00:00:00
abstract::Twelve patients with a diagnosis of schizophrenia and thirteen control subjects were injected with 77Br-bromospiperone and scanned using single photon emission tomography after 16 h. Although a statistically significant increase in patients by comparison with controls could be demonstrated, wide variations in specific...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198608000-00006
更新日期:1986-08-01 00:00:00
abstract::Forty-four patients with symptoms of lower limb arterial insufficiency were examined by radionuclide angiography using 99Tcm in vivo red cell labelling and by contrast aortography. The results of the study indicate that radionuclide angiography may well have a useful role to play in determining the type of contrast st...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198601000-00006
更新日期:1986-01-01 00:00:00
abstract::The efficacy of wipe tests for assessing 99Tcm surface contamination was measured. Four types of surface were contaminated with four radiopharmaceuticals and wiped using four types of swab. The fraction of activity removed was measured by direct monitoring for each combination of surface, pharmaceutical and swab. The ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199102000-00005
更新日期:1991-02-01 00:00:00
abstract:AIM:The aim of this study was to assess ablation outcome after a second ablation dose and compare the ablation rate after low and high reablation doses of iodine-131 ((131)I) after failure of the first ablation with 3700 MBq. PATIENTS AND METHODS:The study included 81 patients with papillary thyroid cancer; they faile...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000233
更新日期:2015-02-01 00:00:00
abstract::Mammography is the screening test of choice for breast cancer. Its low specificity leads to a large number of unnecessary biopsies. Scintimammography, with either Tc-sestamibi (MIBI) or Tc-anti-carcinoembryonic antigen (CEA) Fab', has been proposed as a non-invasive test to lower the high false positive rate of mammog...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200303000-00009
更新日期:2003-03-01 00:00:00
abstract::Radiation doses to the family and general public from 131I therapy of outpatients were assessed for comparison with the 1990 International Commission on Radiation Protection (ICRP) dose limits. Doses to family members of such patients, measured by previous workers, were converted to show that on average 5.6 +/- 3.7 mi...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199309000-00004
更新日期:1993-09-01 00:00:00
abstract::When preparing 99Tcm-exametazime, it is important to use sodium 99Tcm-pertechnetate that is less than 2 h old. The addition of sodium iodide (NaI) to 99Tcm-pertechnetate is known to extend this time to 6 h. This paper describes a technique for implementing this in routine practice. Sterile kits consisting of 440 micro...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199205000-00003
更新日期:1992-05-01 00:00:00