Wipe tests to assess 99Tcm surface contamination: effects of surface type, swab type and chemical form.

Abstract:

:The efficacy of wipe tests for assessing 99Tcm surface contamination was measured. Four types of surface were contaminated with four radiopharmaceuticals and wiped using four types of swab. The fraction of activity removed was measured by direct monitoring for each combination of surface, pharmaceutical and swab. The results obtained showed that wipe tests are neither accurate nor precise. Observed wipe efficacies differed greatly from the customary assumption that 10% of the activity is removed by wiping. Detergent soaked swabs gave a mean efficacy of 40%, although with considerable variation (coefficient of variation 49%). Using these swabs alone the surface type affected efficacy by almost a factor three (floor tile mean efficacy 20%, plastic laminate mean efficacy 57%). In principle this effect might be compensated for by using correction factors according to the surface being swabbed. However, the pharmaceutical type will generally be unknown, and this also affected efficacy by almost a factor of two (eluate mean efficacy 29%, macroaggregated albumin 53%). Overall the results suggest that wipe tests can be used to detect contamination but are unreliable for quantification.

journal_name

Nucl Med Commun

authors

Scott LE,Gibson CJ

doi

10.1097/00006231-199102000-00005

subject

Has Abstract

pub_date

1991-02-01 00:00:00

pages

127-33

issue

2

eissn

0143-3636

issn

1473-5628

journal_volume

12

pub_type

杂志文章
  • Clinical significance of extraskeletal computed tomography findings on 18F-NaF PET/CT performed for osseous metastatic disease evaluation.

    abstract:PURPOSE:Extraskeletal findings detected on whole-body low-dose unenhanced computed tomography (CT) as a part of F-NaF PET/CT scans can be numerous and present challenges for further management. Here, we investigate the frequency and clinical significance of extraskeletal findings among 130 consecutive patients undergoi...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000531

    authors: Guo HH,Moradi F,Iagaru A

    更新日期:2016-09-01 00:00:00

  • Focus localization in patients with partial epilepsy with 99Tcm-HMPAO SPECT under continuous surface EEG monitoring.

    abstract::Our study was aimed at determining the validity of 99Tcm-HMPAO single photon emission computed tomography (SPECT) in the localization of the epileptogenic focus by correlating this diagnostic method with other auxiliary investigations such as surface EEG and X-ray transmission computed tomography (CT). Twenty-eight pa...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199203000-00002

    authors: Verhoeff NP,Weinstein HC,Aldenkamp AP,Overweg J,Van Royen EA,Verbeeten B Jr

    更新日期:1992-03-01 00:00:00

  • Prognostic value of dual-point fluorine-18 fluorodeoxyglucose PET imaging, partial volume correction and glucose transporter-1 expression in resected nonsmall cell lung cancer patients.

    abstract:OBJECTIVE:To investigate the relationship between the prognosis and glucose transporter-1 (Glut-1) expression or fluorine-18 fluorodeoxyglucose uptake using partial volume correction and dual-point imaging in surgically resected nonsmall cell lung cancer (NSCLC) patients. METHODS:Our patient population consisted of 10...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001118

    authors: Kaida H,Azuma K,Kawahara A,Takamori S,Akiba J,Fujimoto K,Ishii K,Ishibashi M

    更新日期:2020-01-01 00:00:00

  • Z-transform method for deconvolution as applied to the renogram.

    abstract::A method of deconvolution analysis involving the use of the z-transform has been developed. When compared to the matrix method, it is shown, under certain circumstances, to be identical. In order to study the validity of the method, simple mathematical models have been constructed. The curves obtained with the compute...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Bererhi H

    更新日期:1995-03-01 00:00:00

  • Value of delayed 18F-FDG-PET imaging in the detection of hepatocellular carcinoma.

    abstract:BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200504000-00003

    authors: Lin WY,Tsai SC,Hung GU

    更新日期:2005-04-01 00:00:00

  • 99mTc galactosyl human serum albumin liver dynamic SPET for pre-operative assessment of hepatectomy in relation to percutaneous transhepatic portal embolization.

    abstract::We have devised an original predictive residual index (PRI) using 99mTc diethylenetriaminepentaacetic acid galactosyl human serum albumin (99mTc-GSA) liver dynamic SPET for the pre-operative assessment of hepatectomy, including the prediction of residual liver function before hepatectomy. The aim of this study was to ...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200307000-00011

    authors: Nishiyama Y,Yamamoto Y,Hino I,Satoh K,Wakabayashi H,Ohkawa M

    更新日期:2003-07-01 00:00:00

  • Three years' clinical practice of Radium-223 therapy in patients with symptomatic bone metastases from metastatic castrate-resistant prostate cancer: a single-centre experience.

    abstract:BACKGROUND:Radium-223 was a treatment approved for patients with metastatic castrate-resistant prostate cancer, symptomatic bone metastases and no-visceral metastases, in progression after at least two prior lines of systemic therapy, or ineligible for any available systemic treatment. The aim of this study was to prov...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001164

    authors: Gazzilli M,Durmo R,Cossalter E,Cerudelli E,Panarotto MB,Albano D,Bertagna F,Giubbini R

    更新日期:2020-04-01 00:00:00

  • Cerebral uptake and retention of 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HM-PAO).

    abstract::A new radiopharmaceutical, 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HM-PAO) is described. This agent displays considerable promise for imaging cerebral blood flow. In studies in rats and one human volunteer, 99Tcm-HM-PAO demonstrates good brain uptake, prolonged retention of activity in the brain, and slow regional...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198508000-00003

    authors: Holmes RA,Chaplin SB,Royston KG,Hoffman TJ,Volkert WA,Nowotnik DP,Canning LR,Cumming SA,Harrison RC,Higley B

    更新日期:1985-08-01 00:00:00

  • Depression and anxiety during isolation and radionuclide therapy.

    abstract::The combination of a diagnosis of malignancy and hospitalization, isolation and radioactivity of a radionuclide therapy may have an important effect on the psychological equilibrium of patients and may hamper compliance and acceptability. We performed a psychiatric evaluation in order to study psycho-pathological mani...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.mnm.0000084586.29433.83

    authors: Brans B,van den Eynde F,Audenaert K,Vervaet M,van Daele K,van Heeringen C,Dierckx RA

    更新日期:2003-08-01 00:00:00

  • Clinical evaluation of hypertrophic cardiomyopathy by myocardial scintigraphy using 123I-labelled 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (123I-BMIPP).

    abstract::To evaluate the clinical utility of 123I-labelled 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (123I-BMIPP), myocardial scintigraphy using 123I-BMIPP was performed in 13 patients with hypertrophic cardiomyopathy (HCM), and the findings were compared with those of 201Tl. The uptake of each tracer was scored visual...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199406000-00008

    authors: Ohtsuki K,Sugihara H,Umamoto I,Nakamura T,Nakagawa T,Nakagawa M

    更新日期:1994-06-01 00:00:00

  • Dosimetric evaluation and therapeutic response to internal radiation therapy of hepatocarcinomas using iodine-131-labelled lipiodol.

    abstract:OBJECTIVE:Vectorized internal radiation therapy using lipiodol-labelled with iodine-131 (131 I-lipiodol) is an effective treatment for inoperable hepatocellular carcinomas. However, few dosimetric data are available based on this approach. We have developed a dosimetric protocol based on scintiscan imaging and that is ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32830439c6

    authors: Becker S,Laffont S,Vitry F,Rolland Y,Lecloirec J,Boucher E,Raoul JL,Herry JY,Bourguet P,Garin E

    更新日期:2008-09-01 00:00:00

  • Myocardial 123I-MIBG kinetics in acutely hypothyroid patients with differentiated thyroid carcinoma.

    abstract::Marked changes in cardiac function have been noted in patients with hyperthyroidism or hypothyroidism due both to changes in sympathetic system function and to biochemical modifications of myocardial tissue. Metaiodobenzylguanidine (MIBG), an analogue of norepinephrine, can be used to evaluate myocardial sympathetic t...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199908000-00006

    authors: Maini CL,Tofani A,Sciuto R,Ferraironi A,Festa A,Rea S

    更新日期:1999-08-01 00:00:00

  • One year's clinical experience of 18F-FDG PET with a modified SPET camera using molecular coincidence detection.

    abstract::High-quality positron emission tomographic (PET) cameras are expensive and, therefore, not available in many centres. To allow access to clinical 18F-fluorodeoxyglucose (18F-FDG) PET, we began working with an ADAC Vertex camera equipped with a molecular coincidence detection (MCD) module in February 1997. Here we give...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-199911000-00005

    authors: Erler H,Zaknun J,Donnemiller E,Bacher-Stier C,Oberladstätter M,Riccabona G,Moncayo R

    更新日期:1999-11-01 00:00:00

  • Are there normal values of phase analysis parameters for left ventricular dyssynchrony in patients with no structural cardiomyopathy?: a systematic review.

    abstract:BACKGROUND:ECG-gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy combined with phase analysis allows for the assessment of left ventricular dyssynchrony. However, there are several software programs available thereby introducing variability in outcome and normal values. The aim ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001068

    authors: Marques de Souza Filho E,Tinoco Mesquita C,Altenburg Gismondi R,de Amorim Fernandes F,Jan Verberne H

    更新日期:2019-10-01 00:00:00

  • (99m)Tc-dextran scintigraphy to detect disease activity in patients with rheumatoid arthritis.

    abstract:AIM:To test the applicability of Tc-dextran joint scintigraphy in the assessment of disease activity in patients with rheumatoid arthritis (RA), and to compare it with the clinical disease activity scores and laboratory parameters. METHODS:Twenty-seven patients with RA were investigated using Tc-dextran joint scintigr...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.mnm.0000126632.32413.2e

    authors: Kaya M,Tuna H,Fatih Firat M,Tuna F,Seren G,Necmi Yigitbasi O

    更新日期:2004-06-01 00:00:00

  • Mediastinal intraoperative radioisotope sentinel lymph node mapping in non-small-cell lung cancer.

    abstract:BACKGROUND:Lymph node metastases are significant prognostic factors in localized non-small-cell lung cancer (NSCLC). Nodal micrometastases may not be detected using current histological methods. AIM:To determine the accuracy and role of sentinel lymph nodes (SLNs) in patients with NSCLC. METHODS:Intraoperative techne...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.mnm.0000169381.99894.2f

    authors: Atinkaya C,Ozlem Küçük N,Koparal H,Aras G,Sak SD,Ozdemir N

    更新日期:2005-08-01 00:00:00

  • Preparation and properties of 99Tcm-exametazime using stannous ion augmentation of fractionated cold kits.

    abstract::Fractionation of 99Tcm-exametazime enables several patients doses to be prepared from one vial. To overcome the disadvantages of storage at -70 degrees C, storage at higher temperatures was investigated with replacement of stannous ions before use. Kits were fractionated using a nitrogen-purged 0.9% w/v sodium chlorid...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199903000-00013

    authors: Baker RJ

    更新日期:1999-03-01 00:00:00

  • Optimizing an 18F-NaF and 18F-FDG cocktail for PET assessment of metastatic castration-resistant prostate cancer.

    abstract:BACKGROUND:PET/computed tomography (CT) imaging with the sodium-(F)-fluoride/2-(F)-fluoro-2-deoxy-D-glucose (F-NaF/F-FDG) cocktail has been proposed for patients with osseous metastases. This work aimed to optimize the cocktail composition for patients with metastatic castration-resistant prostate cancer (mCRPC). MATE...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000383

    authors: Simoncic U,Perlman S,Liu G,Jeraj R

    更新日期:2015-12-01 00:00:00

  • Changes in the rCBF images of patients with Alzheimer's disease receiving Donepezil therapy.

    abstract::Alzheimer's disease is associated with a loss in presynaptic cholinergic function. It has been suggested that cholinergic inhibitors such as donepezil hydrochloride (Donepezil) could restore this function and improve some of the symptoms of Alzheimer's disease. Previous work has shown that Donepezil improves cognitive...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200001000-00007

    authors: Staff RT,Gemmell HG,Shanks MF,Murray AD,Venneri A

    更新日期:2000-01-01 00:00:00

  • A study of leucocyte labelling efficiencies obtained with 111In-oxine.

    abstract::The range of leucocyte labelling efficiencies with 111In-oxine for a group of patients extended significantly (P = 0.05) below that obtained for a series of labellings of the same normal blood from a volunteer. A retrospective analysis was made of the results in the two groups to identify the cause of this difference ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Mountford PJ,Allsopp MJ,Baird AC,North CI,Hall FM,Wells CP,Coakley AJ

    更新日期:1985-02-01 00:00:00

  • (99m)Tc-E-selectin binding peptide for imaging acute osteomyelitis in a novel rat model.

    abstract:INTRODUCTION:In the present study, (99m)Tc-radiolabelled E-selectin binding peptide ((99m)Tc-IMP-178) was investigated for its potential to image acute pyogenic osteomyelitis in a new animal model. Intraindividual comparisons were performed using an irrelevant peptide ((99m)Tc-IMP-100) to demonstrate specificity. METH...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200109000-00010

    authors: Gratz S,Béhé M,Boerman OC,Kunze E,Schulz H,Eiffert H,O'Reilly T,Behr TM,Angerstein C,Nebendahl K,Kauer F,Becker W

    更新日期:2001-09-01 00:00:00

  • 201Tl myocardial perfusion SPET: adenosine alone or combined with dynamic exercise.

    abstract::201Tl myocardial perfusion single photon emission tomography (SPET) with pharmacological coronary vasodilatation using adenosine is now often used in the investigation of a patient with ischaemic heart disease (IHD). In this study, we present data from two groups of patients. Group A (n = 40) experienced 201Tl SPET wi...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-199408000-00003

    authors: Mahmood S,Gupta NK,Gunning M,Bomanji JB,Jarritt PH,Ell PJ

    更新日期:1994-08-01 00:00:00

  • Low-dose computed tomography scans with automatic exposure control for patients of different ages undergoing cardiac PET/CT and SPECT/CT.

    abstract:PURPOSE:This study aimed to evaluate the efficacy of automatic exposure control (AEC) in order to optimize low-dose computed tomography (CT) protocols for patients of different ages undergoing cardiac PET/CT and single-photon emission computed tomography/computed tomography (SPECT/CT). METHODS:One PET/CT and one SPECT...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000679

    authors: Yang CC,Yang BH,Tu CY,Wu TH,Liu SH

    更新日期:2017-06-01 00:00:00

  • Cell uptake and tissue distribution of radioiodine labelled D-luciferin: implications for luciferase based gene imaging.

    abstract::Optical luciferase gene imaging is emerging as a method to monitor gene expression in small animals. However, there is concern over how regional availability of exogenously administered substrate may affect photon emission. We thus synthesized [125I]iodo-D-luciferin, which demonstrated substrate characteristics for fi...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200309000-00009

    authors: Lee KH,Byun SS,Paik JY,Lee SY,Song SH,Choe YS,Kim BT

    更新日期:2003-09-01 00:00:00

  • Shape analysis of 123I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography images in the assessment of patients with parkinsonian syndromes.

    abstract:PURPOSE:The purpose of this study was to show the viability and performance of a shape-based pattern recognition technique applied to I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography (FP-CIT SPECT) in patients with parkinsonism. METHODS:A fully autom...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e328314b863

    authors: Staff RT,Ahearn TS,Wilson K,Counsell CE,Taylor K,Caslake R,Davidson JE,Gemmell HG,Murray AD

    更新日期:2009-03-01 00:00:00

  • Radiolabelled antimicrobial peptides for imaging of infections: a review.

    abstract::At present, it is difficult to distinguish between bacterial infections and sterile inflammatory processes using radiopharmaceuticals. This is so for a variety of reasons, including binding to bacteria with low affinity (e.g. infection) and binding to a specific micro-organism (e.g. radiolabelled monoclonal antibodies...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,评审

    doi:10.1097/00006231-199812000-00002

    authors: Nibbering PH,Welling MM,van den Broek PJ,van Wyngaarden KE,Pauwels EK,Calame W

    更新日期:1998-12-01 00:00:00

  • Comparison of methods for quantification of transient ischaemic dilation in myocardial perfusion SPET.

    abstract::The purpose of this study was to compare six methods of measuring the left ventricular (LV) transient ischaemic dilation (TID) ratio during stress-rest myocardial perfusion single-photon emission tomography (SPET). The TID ratio was defined as the mean LV short-axis area at stress divided by the mean LV area of simila...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200010000-00013

    authors: Peace RA,McKiddie FI,Staff RT,Gemmell HG

    更新日期:2000-10-01 00:00:00

  • 74 MBq radioiodine 131I does not prevent uptake of therapeutic doses of 131I (i.e. it does not cause stunning) in differentiated thyroid cancer.

    abstract::Altogether, 147 scintiscans, completed 48-72 h after 74 MBq 131I, were compared with scintiscans obtained on average 7.8 days after therapeutic doses of 131I. The therapeutic doses ranged from 1100 to just over 7400 MBq. The reasons for the investigation were to determine (1) if the diagnostic dose interfered with upt...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199706000-00002

    authors: McDougall IR

    更新日期:1997-06-01 00:00:00

  • Preparation of radioactive praseodymium oxide as a multifunctional agent in nuclear medicine: expanding the horizons of cancer therapy using nanosized neodymium oxide.

    abstract:OBJECTIVE:Many studies have attempted to assess the significance of the use of the β(-)particle emitter praseodymium-142 ((142)Pr) in cancer treatment. As praseodymium oxide (Pr(2)O(3)) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32835aa7bd

    authors: Bakht MK,Sadeghi M,Ahmadi SJ,Sadjadi SS,Tenreiro C

    更新日期:2013-01-01 00:00:00

  • Improved visualization of perfusion defects by respiratory-gated SPECT: a phantom simulation study.

    abstract:OBJECTIVES:Single-photon emission computed tomography ventilation/perfusion (SPECT V/Q) imaging is recommended both by the Society of Nuclear Medicine and by the European Association of Nuclear Medicine for the diagnosis of pulmonary embolism. However, respiratory motion produces image blurring and degradation of detai...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000015

    authors: Darwesh RM,Shin E,Morgan PS,Perkins AC

    更新日期:2014-02-01 00:00:00