Comparison of methods for quantification of transient ischaemic dilation in myocardial perfusion SPET.

Abstract:

:The purpose of this study was to compare six methods of measuring the left ventricular (LV) transient ischaemic dilation (TID) ratio during stress-rest myocardial perfusion single-photon emission tomography (SPET). The TID ratio was defined as the mean LV short-axis area at stress divided by the mean LV area of similar slices at rest. The centre of the LV wall was defined as either the maximum, mean or median of the radial short-axis count profiles. The area within the endocardial wall was also calculated for each definition of the LV wall centre. We identified 50 consecutive patients undergoing dipyridamole technetium-99m-tetrofosmin SPET imaging and angiography. Continuous receiver operating characteristic (CROC) analysis showed no significant difference between the six methods in terms of identifying severe coronary artery disease (P >0.47). Algorithms using the mean or the median value in the profile were significantly more robust than those using the maximum (P <0.0005). TID measured by all the algorithms is an indicator of severe coronary disease (P < 0.05). The algorithms compared provide a repeatable, quantitative and specific measure of the TID ratio.

journal_name

Nucl Med Commun

authors

Peace RA,McKiddie FI,Staff RT,Gemmell HG

doi

10.1097/00006231-200010000-00013

keywords:

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

971-6

issue

10

eissn

0143-3636

issn

1473-5628

journal_volume

21

pub_type

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