Abstract:
:Altogether, 147 scintiscans, completed 48-72 h after 74 MBq 131I, were compared with scintiscans obtained on average 7.8 days after therapeutic doses of 131I. The therapeutic doses ranged from 1100 to just over 7400 MBq. The reasons for the investigation were to determine (1) if the diagnostic dose interfered with uptake of the therapeutic dose and (2) how often more lesions, or greater extent of disease, was seen on the images using the larger therapy dose. The post-treatment scan showed less uptake in one region in 2 of the 147 patients (1.4%). The post-treatment scan showed more lesions in 12 patients (8%). In eight patients, the extent of disease, but not the stage of disease, was greater. In four patients, the stage of disease was increased, three due to lung uptake on the post-treatment scan which was not seen on the diagnostic scan and one due to uptake in lymph nodes on the post-treatment scan which was not present on the diagnostic scan. 74 MBq 131I seldom interferes with subsequent therapy and seldom underestimates the extent of thyroid cancer. It would appear to be an appropriate dose for diagnostic scintigraphy.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
McDougall IRdoi
10.1097/00006231-199706000-00002subject
Has Abstractpub_date
1997-06-01 00:00:00pages
505-12issue
6eissn
0143-3636issn
1473-5628journal_volume
18pub_type
杂志文章abstract:OBJECTIVE:To measure and describe patterns of interobserver variation in visual interpretation of 18-FDG PET in malignant lymphoma. METHODS:Eleven nuclear medicine physicians with different levels of PET experience independently reviewed 37 18F-FDG PET scans of lymphoma patients (10 obtained at presentation, 27 during...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282eff2d5
更新日期:2007-10-01 00:00:00
abstract:INTRODUCTION:It has been suggested that renal retention function can be estimated by differentiation of the Patlak-Rutland plot. AIM:To evaluate the error resulting from this method. METHODS:A total of 5800 renograms were generated by convolving real input functions with artificial retention functions. Ten bi-exponen...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200405000-00012
更新日期:2004-05-01 00:00:00
abstract::A number of authors have indicated a more sensitive detection of renal cortical defects using single photon emission tomography (SPET) compared with planar imaging when performing 99Tcm-dimer-captosuccinic acid (99Tcm-DMSA) renal scintigraphy. The place of SPET in the evaluation of kidneys in adults suspected of acute...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::A significant number of patients with primary hyperparathyroidism have negative preoperative 201Tl/99Tcm subtraction localization scans. In this study an attempt was made to improve scan localization by creating a period of relative hypocalcaemia and increased parathyroid hormone (PTH) secretion before scanning. Six p...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199109000-00005
更新日期:1991-09-01 00:00:00
abstract:INTRODUCTION:Gated myocardial perfusion scintigraphy (g-MPS) provides functional information on the left ventricle (LV) apart from the perfusion status. Computer algorithm-based LV ejection fraction (EF) calculated from resting g-MPS has been found to be reliable in patients with normal perfusion. However, its role in ...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e328342b97e
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:Ga-PSMA-11 is a novel PET tracer suggested to be used for imaging of advanced prostate cancer. In this study, we aimed to present a detailed biodistribution of Ga-PSMA-11, including physiological and benign variants of prostate-specific membrane antigen (PSMA) imaging. MATERIALS AND METHODS:We carried out a re...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000566
更新日期:2016-11-01 00:00:00
abstract::Venous thromboembolism (VTE) can present as deep vein thrombosis (DVT) and/or acute pulmonary embolism (PE). In fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT, 18F-FDG activity along the deep veins of the lower extremities (LE) is often observed and, unless it is associated with focal intense activity, is not conside...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000442
更新日期:2016-03-01 00:00:00
abstract::Pentavalent 99Tcm-dimercaptosuccinic acid (99Tcm-(V)DMSA) has an established role in imaging medullary thyroid carcinoma. There have been case reports of uptake in bone metastases. Our aims were to compare 99Tcm-(V)DMSA with 99Tcm-hydroxymethylene diphosphonate (99Tcm-HDP) in bone metastases, to assess its value in im...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-199710000-00003
更新日期:1997-10-01 00:00:00
abstract::In order to compare visual interpretation of inflammation detected by leukocyte scintigraphy with that of different computer-aided quantification methods, 34 patients (25 with ulcerative colitis and 9 with endoscopically verified non-inflamed colonic mucosa), were investigated using 99Tcm-hexamethylpropyleneamine oxim...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199504000-00161
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to validate the efficacy of computed tomography (CT) iterative reconstruction (CT-IR) for low-dose CT attenuation correction in terms of the estimation of attenuation coefficient and quality of PET images. MATERIALS AND METHODS:We used normal and obesity-simulating body phantoms. PE...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000326
更新日期:2015-08-01 00:00:00
abstract::21 patients with Wolff-Parkinson-White (WPW) syndrome were investigated through radionuclide imaging and body surface mapping. Ventricular preexcitation was localized by display of identical phase ventricular regions (phase display). In 79% of the cases radioisotope and body surface mapping methods have identical resu...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198607000-00004
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the capability of F-FDG PET/computed tomography (CT)-related metabolic parameters to predict lymph node metastasis (LNM) and occult lymph node metastasis (OLNM) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:Totally 84 patients undergoing curative...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001050
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the relationship between fluorine-18 fluorodeoxyglucose (F-FDG) uptake and molecular biological markers in esophageal squamous cell carcinoma (ESCC) patients. METHODS:Our patient population included 51 patients who underwent F-FDG PET/computed tomography before surgery. Ex...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000550
更新日期:2016-10-01 00:00:00
abstract:AIM:To develop a strategy for checking the reliability of slope intercept measurement of glomerular filtration rate (GFR). METHODS:Six blood samples, obtained bilaterally 20-240 min after the injection of Cr-ethylenediaminetetraacetic acid (EDTA) and iohexol into opposite arms, were assayed for indicator injected cont...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328310b378
更新日期:2008-12-01 00:00:00
abstract::This study surveyed practice in nuclear cardiology in the UK in 1994. A questionnaire was sent to 219 centres performing nuclear imaging asking for details of current practice in nuclear cardiology. Replies were received from 192 centres (88%). Activity in performance of myocardial perfusion imaging (MPI) and radionuc...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199804000-00004
更新日期:1998-04-01 00:00:00
abstract::Good working practice and legal obligation impose a duty on nuclear medicine departments to check syringe activities before administration to a patient. If syringe guards are used to reduce staff exposure while drawing up injections, the guard has to be removed to measure the activity in a conventional reentrant ioniz...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199708000-00013
更新日期:1997-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to show the viability and performance of a shape-based pattern recognition technique applied to I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography (FP-CIT SPECT) in patients with parkinsonism. METHODS:A fully autom...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328314b863
更新日期:2009-03-01 00:00:00
abstract::N-isopropyl-p-I-123-iodoamphetamine (123I-IMP) is extracted by the brain in proportion to regional blood flow. It is particularly useful in the clinical assessment of various pathological conditions related to altered cerebral flow. Moreover, it has been reported that 123I-IMP is avidly incorporated into melanin and m...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199602000-00010
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND AND AIM:To evaluate the diagnostic value of integrated 18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT) to discriminate malignant from benign ovarian tumors. METHODS:One hundred and eight women suspected of having ovarian cancer underwent preoperative FDG-PET/CT sca...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328345b339
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic (18)F-fluorodeoxyglucose ((18)F-FDG) uptake. In this study, we focused on cytokines to investigate interactions during this phenomenon and clarify the significance of splenic (18)F-...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e3283595cac
更新日期:2013-01-01 00:00:00
abstract:AIM:The first pathogenetic step in multiple myeloma is the emergence of a limited number of clonal plasma cells, clinically known as monoclonal gammopathy of undetermined significance (MGUS). Patients with MGUS do not have symptoms or end-organ damage but they do have a 1% annual risk of progression to multiple myeloma...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f5e5df
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:In this study, primary tumors' fluorine-18-fluorodeoxyglucose (F-FDG) uptake in luminal A, luminal B, triple-negative, and human epidermal growth factor receptor type-2 subtypes of breast cancer was evaluated. In addition, the relationship between the primary tumor maximum standardized uptake value (SUVmax) v...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000856
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to assess the degree and location of the reparative process in early osteonecrosis of the femoral head on the basis of single-photon emission computed tomography/computed tomography (SPECT/CT) with technetium-99m hydroxymethylene diphosphonate. MATERIALS AND METHODS:This study was ap...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000166
更新日期:2014-10-01 00:00:00
abstract::The aim of the study was to identify the most beneficial mode, in terms of anxiety reduction, of giving patients information prior to them undergoing a bone scan. (Research has identified the scan procedure as having a demonstrative effect on anxiety.) Additionally, satisfaction with the adequacy of the information wa...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-199411000-00011
更新日期:1994-11-01 00:00:00
abstract::This paper considers the different statistics that can be derived from studies on the value of diagnostic tests. Well-accepted quantities, such as sensitivity and specificity, are reviewed and the value of the likelihood ratio in communicating particular test results is highlighted. A new quantity, the 'diagnostic val...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/00006231-199810000-00010
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to assess the influence of different normalization procedures on relative changes in standardized uptake values (SUV) of F-2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) for the assessment of chemotherapy response in patients with colorectal carcinoma ...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e32832bdc80
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:Medullary thyroid carcinoma is a rare, potentially aggressive tumour, with relatively worse prognosis than well-differentiated thyroid cancer. We evaluated the long-term outcomes and prognosis of medullary thyroid carcinoma patients at a single institution in India and compared outcomes based on results of RE...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001264
更新日期:2020-11-01 00:00:00
abstract::The ICRP has now recommended that the dose limit to the surface of the mother's abdomen during the declared term of pregnancy is reduced to 2 mSv. Direct measurements of the radiation dose to technologists carrying out a variety of imaging studies were made. The average dose ranged from 0.3 micro Sv for a liver scan t...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199211000-00004
更新日期:1992-11-01 00:00:00
abstract::An accurate evaluation of the absorbed dose to the bladder wall from 2-[(18)F]fluoro-2-deoxy-d-glucose (FDG) is clinically important because the bladder is considered as a critical organ in most positron emission tomography (PET) studies that cumulate about 20% of the total activity injection during image procedures. ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200208000-00008
更新日期:2002-08-01 00:00:00
abstract::We studied two different methods for the evaluation of differential renal function in a group of 100 patients with various kidney disorders whose effective renal plasma flow (ERPF) had been calculated previously by single 125I-orthoiodohippurate (OIH) injection and multiple blood sampling. Patients were divided into t...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198910000-00008
更新日期:1989-10-01 00:00:00