Quantifying the value of diagnostic tests.

abstract：BACKGROUND:Coronary artery disease is a leading cause of morbidity and mortality. Multiple imaging modalities are used to screen for significant coronary artery disease. We report the concordance between coronary computed tomography angiography (CTA) and stress cardiac positron emission tomography (CPET) to detect sign...

journal_title：Nuclear medicine communications

authors： Adams GL,Trimble MA,Brosnan RB,Russo CA,Rusband D,Honeycutt EF,Shaw LK,Hurwitz LM,Turkington TG,Hanson MW,Pagnanelli RA,Borges-Neto S

更新日期：2008-07-01 00:00:00

abstract：:In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

journal_title：Nuclear medicine communications

authors： Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

更新日期：1989-11-01 00:00:00

abstract：:Cystic fibrosis patients require pancreatic enzyme supplements to aid food digestion. It is suspected that incorrect delivery of this enzyme may result in both significant malabsorption and the development of strictures in the proximal colon caused by the high-dose supplement reaching this region before the food. Inve...

journal_title：Nuclear medicine communications

authors： Hillel PG,Tindale WB,Taylor CJ,Frier M,Senior S,Ghosal S

更新日期：1998-08-01 00:00:00

abstract：:The ability of 99Tcm-methoxyisobutylisonitrile (MIBI) single photon emission tomography (SPET) to detect myocardial ischaemia and necrosis was assessed in 56 patients (45 male, 11 female, aged 55 +/- 5 years), with clinically recognized ischaemic heart disease (IHD). All underwent coronary angiography (CA) and left ve...

journal_title：Nuclear medicine communications

authors： Sciammarella MG,Fragasso G,Gerundini P,Maffioli L,Cappelletti A,Margonato A,Savi A,Chierchia S

更新日期：1992-12-01 00:00:00

abstract：:Radionuclide limb blood flow measurements using 99Tcm-labelled human serum albumin and a gamma camera have been performed on normal volunteers and on patients with suspected or confirmed peripheral arterial disease. The normal range of flow was found to be 10.0-22.3 ml per 100 ml tissue per min. Flow in the symptomati...

journal_title：Nuclear medicine communications

authors： Parkin A,Robinson PJ,Martinez D,Wilkinson D,Kester RC

更新日期：1991-10-01 00:00:00

abstract：:The main aim of this study was to investigate the role of N-(2,4,6 trimethyl-3-bromophenylcarbamoylmethyl) iminodiacetic acid (IDA; Mebrofenin) scintigraphy in follow-up assessments of the biliary system in patients with cystic fibrosis associated liver disease. Fourteen patients from a study published in 1996 were re...

journal_title：Nuclear medicine communications

authors： Foster JA,Ramsden WH,Conway SP,Taylor JM,Etherington C

更新日期：2002-07-01 00:00:00

abstract：AIM:To perform a detailed analysis of the performance of mobile intraoperative imaging systems and gamma probes in a phantom set-up, and compare this with a conventional gamma camera. METHODS:Two separate experiments were performed. In the first, a modified Jaszczak phantom equipped with five (99m)Tc-filled hot sphere...

journal_title：Nuclear medicine communications

authors： Krohn T,Verburg FA,Brockmann H,Winz OH,Mottaghy FM,Behrendt FF

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Increasing evidence, primarily from animal studies and patients with compromised neurotransmitter systems, indicates a possibly important role for dopamine in modulating sleep. We therefore conducted this study to explore the relation between sleep and dopamine in healthy adults. METHODS:We used the Pittsburgh...

journal_title：Nuclear medicine communications

authors： Lee BF,Chiu NT,Kuang Yang Y,Lin Chu C

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Paediatric dual X-ray absorptiometry (DXA) studies present a number of technical problems. One of these is that the edge detection algorithms designed for the adult skeleton may fail for paediatric studies. Hologic provide alternative algorithms for low bone density studies. AIM:To assess low-density softwa...

journal_title：Nuclear medicine communications

authors： Simpson DE,Dontu VS,Stephens SE,Archbold LJ,Lowe V,O'Doherty MJ,Martin N,Coakley AJ

更新日期：2005-06-01 00:00:00

abstract：:N-isopropyl-p-I-123-iodoamphetamine (123I-IMP) is extracted by the brain in proportion to regional blood flow. It is particularly useful in the clinical assessment of various pathological conditions related to altered cerebral flow. Moreover, it has been reported that 123I-IMP is avidly incorporated into melanin and m...

journal_title：Nuclear medicine communications

authors： Watanabe N,Seto H,Yokoyama K,Matsuda H,Shimizu M,Tonami N,Hisada K,Kakishita M

更新日期：1996-02-01 00:00:00

abstract：PURPOSE:To test the potential of a new reconstruction algorithm with Monte Carlo-based scatter correction in half-time myocardial perfusion single-photon emission computed tomography (SPECT). MATERIALS AND METHODS:The mathematical four-dimensional NURBS-based Cardiac-Torso phantom and the SIMIND Monte Carlo simulation...

journal_title：Nuclear medicine communications

authors： Kangasmaa TS,Kuikka JT,Vanninen EJ,Mussalo HM,Laitinen TP,Sohlberg AO

更新日期：2011-11-01 00:00:00

abstract：AIM:To evaluate the biodistribution, internal radiation dosimetry and toxicity of the humanized MAb h-R3 labelled with Tc in humans. METHODS:Twenty-five patients with suspected epithelial-derived tumours were included in this study and divided into two groups: group I consisted of 10 patients who received 3 mg/1110 MB...

journal_title：Nuclear medicine communications

authors： Torres LA,Perera A,Batista JF,Hernández A,Crombet T,Ramos M,Neninger E,Pérez M,Sánchez EL,Romero S,Aguilar V,Coca MA,Iznaga-Escobar N

更新日期：2005-12-01 00:00:00

abstract：AIM:To develop a strategy for checking the reliability of slope intercept measurement of glomerular filtration rate (GFR). METHODS:Six blood samples, obtained bilaterally 20-240 min after the injection of Cr-ethylenediaminetetraacetic acid (EDTA) and iohexol into opposite arms, were assayed for indicator injected cont...

journal_title：Nuclear medicine communications

authors： Bird NJ,Peters C,Michell AR,Peters AM

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:Despite the growing use of fluorine-18-fluorodeoxyglucose (F-FDG) PET texture analysis to measure intratumoural heterogeneity in cancer research, the biologic basis of F-FDG PET-derived texture variables is poorly understood. We aimed to assess correlations between F-FDG PET-derived texture variables and whole-...

journal_title：Nuclear medicine communications

authors： Bashir U,Foot O,Wise O,Siddique MM,Mclean E,Bille A,Goh V,Cook GJ

更新日期：2018-12-01 00:00:00

abstract：:Polyphosphonate ligands labelled with radioisotopes decaying by moderate energy beta emission have shown utility as palliative agents for painful bone metastasis. 177Lu (T(1/2)=6.71 d, Ebetamax=497 keV) has radionuclidic properties suitable for use in palliative therapy of bone metastasis. 177Lu was produced at a high...

journal_title：Nuclear medicine communications

authors： Chakraborty S,Das T,Unni PR,Sarma HD,Samuel G,Banerjee S,Venkatesh M,Ramamoorthy N,Pillai MR

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The recent introduction of high-efficiency solid-state gamma cameras for myocardial perfusion single photon emission computed tomography has enabled lower patient radiation dose, faster imaging, and improved image quality. However, artifacts still complicate interpretation. Prone imaging is a common maneuver ...

journal_title：Nuclear medicine communications

authors： Howard BA,Roy Choudhury K,Oldan JD,Pagnanelli RA,Borges-Neto S

更新日期：2016-05-01 00:00:00

abstract：:123I-labelled 15-(p-iodophenyl)-9-(R,S)-methylpentadecanoic acid (9MPA) is a modified long-chain fatty acid that shows some beta-oxidation. Some basic aspects of this fatty acid, including myocardial uptake, distribution, clearance and differences from 201Tl myocardial perfusion, have yet to be evaluated. An average o...

journal_title：Nuclear medicine communications

authors： Nakajima K,Taki J,Yamamoto W,Takata S,Shimizu M,Tonami N

更新日期：1998-09-01 00:00:00

abstract：:The criteria governing the in vivo use of monoclonal antibodies in humans are based upon a number of legal requirements with respect to radiation hygiene, pharmaceutical legislation, radiopharmaceutical legislation and regulations with respect to products arising from biotechnology. This in itself has led to a complic...

journal_title：Nuclear medicine communications

authors： Cox PH

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:Nuclear medicine procedures are often performed in close-time proximity to bone densitometry studies. The purpose of this study was to determine the effects of Tc-hexakis-2-methoxyisobutyl isonitrile (MIBI) and Tc-methylene diphosphonate (MDP) on the accuracy of bone mineral density (BMD) measurements perform...

journal_title：Nuclear medicine communications

authors： Gumuser G,Parlak Y,Topal G,Aras F,Ruksen E,Sayit E

更新日期：2009-06-01 00:00:00

abstract：AIM AND PURPOSE:Radionuclide imaging of the kidneys using dimercaptosuccinic acid chelate labeled with technetium-99m (Tc-DMSA) is a well-established method for evaluating the extent of kidney parenchymal involvement in the scenario of urinary tract infection and for the estimation of the functional renal mass. We have...

journal_title：Nuclear medicine communications

authors： Gorenberg M,Radan L,Kosakov R,Amirav I

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:Extraskeletal findings detected on whole-body low-dose unenhanced computed tomography (CT) as a part of F-NaF PET/CT scans can be numerous and present challenges for further management. Here, we investigate the frequency and clinical significance of extraskeletal findings among 130 consecutive patients undergoi...

journal_title：Nuclear medicine communications

authors： Guo HH,Moradi F,Iagaru A

更新日期：2016-09-01 00:00:00

abstract：:Published values of tissue weighting factors for adolescents and children derived from the life-span study of the atomic bomb survivors have been used to calculate the effective dose to patients aged 1, 5, 10 and 15 years undergoing a common paediatric procedure requiring one of the following radiopharmaceuticals: 99T...

journal_title：Nuclear medicine communications

authors： Gadd R,Mountford PJ,Oxtoby JW

更新日期：1999-06-01 00:00:00

abstract：:To study the accuracy of renal function quantification with 99Tcm-DMSA we compared DMSA renal uptake and creatinine clearance in 16 cases of children with single kidney. The age of the patients ranged from two months to fourteen years. Creatinine clearance was normalized to 1.73 m2. DMSA uptake was measured 7 h after ...

journal_title：Nuclear medicine communications

authors： Baillet G,Gagnadoux MF,De Vernejoul P,Broyer M

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:We investigated the role of Ga-68 DOTATATE PET/CT in comparison to F-18 FDG PET/CT in patients with low and intermediate versus high-grade neuroendocrine tumors (NETs). METHODS:We identified 81 patients who underwent Ga-68 DOTATATE PET/CT at our institution between May 2017 and December 2018 and met inclusio...

journal_title：Nuclear medicine communications

authors： You H,Kandathil A,Beg M,De Blanche L,Kazmi S,Subramaniam RM

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the success rate in lymphatic mapping and sentinel node biopsy in breast cancer using two radiopharmaceuticals. METHODS:The study included 119 breast cancer patients who underwent lymphoscintigraphy after a single intratumoral injection of 99mTc-labelled human albumin co...

journal_title：Nuclear medicine communications

authors： Leidenius MH,Leppänen EA,Krogerus LA,Smitten KA

更新日期：2004-03-01 00:00:00

abstract：:INTRODUTION:: [Ga]Ga-prostate specific membrane antigen (PSMA)-11 showed a clear gain in sensitivity for lesion detection in the biological recurrence of prostate cancer as compared to the standard [F]fluorocholine radiopharmaceutical. To meet the strong demand for [Ga]Ga-PSMA-11, we aimed to optimize an automated rad...

journal_title：Nuclear medicine communications

authors： Reverchon J,Khayi F,Roger M,Moreau A,Kryza D

更新日期：2020-06-18 00:00:00

abstract：:An analysis of lymphocyte subsets was performed in 24 patients with surgically verified unresectable hepatocellular carcinoma (HCC). In all cases, the hepatic artery was cannulated and ligated and a single dose of 131I-Hepama-1 monoclonal antibody (MAb) was infused through a hepatic artery catheter. Blood samples were...

journal_title：Nuclear medicine communications

authors： Zeng ZC,Tang ZY,Liu KD,Yu YQ,Yang BH,Cai XJ,Xie H,Cao SL

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:Simulated data from the recent Institute of Physics and Engineering in Medicine audit of quantitative cerebral perfusion were used to optimize the parameters of eigenimage analysis, a method for computer-aided detection. METHODS:Twenty normal images provided by the audit were registered to the International ...

journal_title：Nuclear medicine communications

authors： Houston AS,Fleming JS,Ward T,Hoffmann SM

更新日期：2009-09-01 00:00:00

abstract：:To make quantitative methods of nuclear medicine more available, four centres in Croatia participated in the national intercomparison study, following the materials and methods used in the previous international study organized by the International Atomic Energy Agency (IAEA). The study task was to calculate the activ...

journal_title：Nuclear medicine communications

authors： Grošev D,Gregov M,Wolfl MR,Krstonošić B,Debeljuh DD

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:Myocardial perfusion SPECT is frequently affected by artefacts related to abdominal activity. Metoclopramide has been suggested to relieve this, but two previous studies have shown conflicting results. METHODS:Ninety-five patients received 10 mg metoclopramide orally after injection of 99mTc-tetrofosmin for...

journal_title：Nuclear medicine communications

authors： Grüning T,Brogsitter C,Khonsari M,Jones IW,Nevin SM,Burchert W

更新日期：2006-12-01 00:00:00