Criteria for the use of monoclonal antibodies, legislation and ethical considerations.

abstract：:The results of scintigraphy in 29 patients with Cushing's syndrome were evaluated. It was possible to separate bilateral hyperplasia from unilateral abnormality. In cases of unilateral abnormality correct localization of the tumour was accomplished and it was possible to visualize adrenocortical carcinoma. The many ad...

journal_title：Nuclear medicine communications

authors： Lindberg S,Ernest I,Fjälling M,Holmdahl C

更新日期：1985-01-01 00:00:00

abstract：:The uptake of 123I-5-iodo-2-thiouracil in melanotic and amelanotic melanoma implanted in Syrian golden hamsters was studied. A selective accumulation was found in the tumours. Uptake of 123ITU in melanotic melanomas was 4 to 5 times the uptake in amelanotic ones. For both tumours high ratios of tumours versus non-tumo...

journal_title：Nuclear medicine communications

authors： Franken NA,Van Langevelde A,Journée-De Korver JG,Bakker CN,Feitsma RI,Van Delft JL,Oosterhuis JA,Pauwels EK

更新日期：1985-10-01 00:00:00

abstract：INTRODUCTION:The metabotropic glutamate receptor subtype 5 (mGluR5) is distributed throughout the central nervous system (CNS), and has been suggested to be a potential target for several CNS disorders suchas Parkinson's disease, pain, anxiety, depression, schizophrenia, and addiction. We report here on the rhesus monk...

journal_title：Nuclear medicine communications

authors： Bélanger MJ,Krause SM,Ryan C,Sanabria-Bohorquez S,Li W,Hamill TG,Burns HD

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:The uptake of F-fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) is known to be linked to programmed death ligand 1 (PD-L1) expression on tumor cells (TC). However, the association between PD-L1 expression on immune cells (IC) and F-FDG accumulation is still unclear. Here, we conducted a clinicopatholo...

journal_title：Nuclear medicine communications

authors： Hu B,Xiao J,Xiu Y,Fu Z,Shi H,Cheng D

更新日期：2020-03-01 00:00:00

abstract：:Pentavalent 99Tcm-dimercaptosuccinic acid (99Tcm-(V)DMSA) has an established role in imaging medullary thyroid carcinoma. There have been case reports of uptake in bone metastases. Our aims were to compare 99Tcm-(V)DMSA with 99Tcm-hydroxymethylene diphosphonate (99Tcm-HDP) in bone metastases, to assess its value in im...

journal_title：Nuclear medicine communications

authors： Lam AS,Kettle AG,O'Doherty MJ,Coakley AJ,Barrington SF,Blower PJ

更新日期：1997-10-01 00:00:00

abstract：:The purpose of this study was to evaluate whether an extension of the imaging time to 24 h post-injection improves the diagnostic accuracy of technetium-99m-hexamethylpropyleneamine oxime (99mTc-HMPAO) leucocyte imaging in detecting knee replacement infections. Thirty patients were studied, with infection confirmed in...

journal_title：Nuclear medicine communications

authors： Larikka MJ,Ahonen AK,Junila JA,Niemelä O,Hämäläinen MM,Syrjälä HP

更新日期：2001-10-01 00:00:00

abstract：:A significant number of patients with primary hyperparathyroidism have negative preoperative 201Tl/99Tcm subtraction localization scans. In this study an attempt was made to improve scan localization by creating a period of relative hypocalcaemia and increased parathyroid hormone (PTH) secretion before scanning. Six p...

journal_title：Nuclear medicine communications

authors： Gallacher SJ,Fraser WD,Logue FC,Boyle IT,Gray HW,McKillop JH

更新日期：1991-09-01 00:00:00

abstract：:In order to compare visual interpretation of inflammation detected by leukocyte scintigraphy with that of different computer-aided quantification methods, 34 patients (25 with ulcerative colitis and 9 with endoscopically verified non-inflamed colonic mucosa), were investigated using 99Tcm-hexamethylpropyleneamine oxim...

journal_title：Nuclear medicine communications

authors： Almer S,Peters AM,Ekberg S,Franzén L,Granerus G,Ström M

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The widely applied F-FDG is known for its disadvantage in brain tumour PET imaging because of its high background uptake. C-choline can achieve high contrast of brain tumour imaging and was expected to have higher sensitivity and specificity. We analysed the misdiagnoses in C-choline PET imagin...

journal_title：Nuclear medicine communications

authors： Huang Z,Zuo C,Guan Y,Zhang Z,Liu P,Xue F,Lin X

更新日期：2008-04-01 00:00:00

abstract：:Monoclonal antibody (MoAb) fragments are known to have advantages over intact immunoglobulins for radioimmunoscintigraphy. It is less clear whether they are as effective in the delivery of radioimmunotherapy. The imaging and dosimetric properties of an intact MoAb, K-1-21, reactive against human kappa light chains (LC...

journal_title：Nuclear medicine communications

authors： Walker KZ,Seymour-Munn K,Towson JE,Axiak SM,Raison RL,Bautovitch GJ,Morris J,Basten A

更新日期：1988-07-01 00:00:00

abstract：:The combined use of 123I-BMIPP and 99Tcm-MIBI SPET imaging has been proposed as an alternative to PET for the non-invasive detection of jeopardized myocardium after a myocardial infarction, a mismatch accurately indicating jeopardized but still viable tissue. In this paper, a new quantitative approach is described, ex...

journal_title：Nuclear medicine communications

authors： Hambÿe AS,Dobbeleir A,Franken PR

更新日期：1997-12-01 00:00:00

abstract：AIM:99mTc-HL91 is a new hypoxia agent and can identify acutely ischaemic viable myocardium in a canine model using a standard gamma camera. The purpose of the study was to determine whether this tracer could be used to detect regional ischaemia in chronic ischaemic myocardium in a swine model. METHOD:Using a porcine m...

journal_title：Nuclear medicine communications

authors： Wu YW,Lee CM,Huang YH,Chou NK,Yen RF,Tzen KY,Huang PJ

更新日期：2005-12-01 00:00:00

abstract：:In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

journal_title：Nuclear medicine communications

authors： Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

更新日期：1989-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to show the viability and performance of a shape-based pattern recognition technique applied to I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography (FP-CIT SPECT) in patients with parkinsonism. METHODS:A fully autom...

journal_title：Nuclear medicine communications

authors： Staff RT,Ahearn TS,Wilson K,Counsell CE,Taylor K,Caslake R,Davidson JE,Gemmell HG,Murray AD

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:The value of gated single-photon emission computed tomography technetium-99m methoxyisobutylisonitrile (gated SPECT (99m)Tc-MIBI) in children is not yet established probably because gated SPECT (99m)Tc-MIBI has rarely been used in pediatric clinical and research studies. The purpose of this study was to eval...

journal_title：Nuclear medicine communications

authors： Sobic-Saranovic DP,Pavlovic SV,Jovanovic IV,Stefanovic ID,Artiko VM,Djukic MM,Obradovic VB

更新日期：2010-01-01 00:00:00

abstract：:Fever of unknown origin is defined as a temperature above 39.0 degrees C together with a white blood cell count > or = 15,000 mm-3, the duration of fever exceeding 2 weeks and a correct diagnosis not being obtained in the first week of hospitalization. In neonates and infants with fever of unknown origin, the localiza...

journal_title：Nuclear medicine communications

authors： Gratz S,Behr TM,Herrmann A,Meller J,Conrad M,Zappel H,Becker W

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:Neurokinin 1 (NK1) receptors have been implicated in depression, anxiety, and pain perception. Recently, it was shown that, in the human brain, a specific NK1 receptor-related signal was obtained with the novel radioligand, [¹¹C]R116301, using positron emission tomography. The purpose of this study was to evalu...

journal_title：Nuclear medicine communications

authors： Wolfensberger SP,Maruyama K,van Berckel BN,Lubberink M,Airaksinen AJ,Boellaard R,Luurtsema G,Reddingius W,Janssens FE,Veltman DJ,Windhorst AD,Leysen JE,Lammertsma AA

更新日期：2011-10-01 00:00:00

abstract：AIM:The aim of this study was to investigate the value of cystatin C and beta-trace protein (BTP) levels in determination of the glomerular filtration rate (GFR) by accepting the technetium-99m diethylenetriamine pentaacetic acid (Tc-DTPA) method as the gold standard for GFR measurement in renal transplant patients wit...

journal_title：Nuclear medicine communications

authors： Oner AO,Aydin F,Demirelli S,Budak ES,Davran F,Akbas H,Kocak H,Suleymanlar G,Gungor F

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:Yttrium-90 (Y)-resin microspheres are prescribed using activity. We evaluated overall survival (OS) and radiographic tumor response after selective internal radiation therapy (SIRT) with resin microspheres in patients with liver metastases from colorectal cancer. PATIENTS AND METHODS:We retrospectively reviewe...

journal_title：Nuclear medicine communications

authors： Badiyan S,Bhooshan N,Chuong MD,Sharma N,Akhter N,Etezadi V,Hausner P,Kudryasheva S,Kaiser A,Becker S,Guerrero M,Yi BY

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to analyze the uptake of rubidium in malignant tumors. PARTICIPANTS AND METHODS:Sixteen malignant lesions were included. Two radiologists compared each lesion to four references (subcutaneous fat, lung, mediastinal blood pool, and liver) at rest and stress and scored as 1-4. M...

journal_title：Nuclear medicine communications

authors： Khandani AH,Commander CW,Desai H,Oldan JD,Wong TZ,Benefield T,Ivanovic M

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is known that fluorine-18 fluorodeoxyglucose PET/computed tomography (CT) segmentation algorithms have an impact on the metabolic tumor volume (MTV). This leads to some uncertainties in PET/CT guidance of tumor radiotherapy. The aim of this study was to investigate the effect of segmentation a...

journal_title：Nuclear medicine communications

authors： Xu W,Yu S,Ma Y,Liu C,Xin J

更新日期：2017-03-01 00:00:00

abstract：:This paper proposes the utilization of 225Ac for the alpha-radioimmunotherapy of cancer. The isotope decays with a radioactive half-life of 10 days into a cascade of short-lived alpha- and beta-emitting isotopes. In addition, when indicated by the pharmacokinetic requirements of particular clinical applications, 213Bi...

journal_title：Nuclear medicine communications

authors： Geerlings MW,Kaspersen FM,Apostolidis C,van der Hout R

更新日期：1993-02-01 00:00:00

abstract：:Providing information to patients and staff is an important part of the practice of nuclear medicine. To assist in improving the standard of communications, guidance has been prepared covering the content, style and presentation of letters and leaflets for patients and for medical and nursing staff. Examples are provi...

journal_title：Nuclear medicine communications

authors： Clarke SE,McKillop JH,Prescott MC,Williams ED

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND AND AIM:To evaluate the diagnostic value of integrated 18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT) to discriminate malignant from benign ovarian tumors. METHODS:One hundred and eight women suspected of having ovarian cancer underwent preoperative FDG-PET/CT sca...

journal_title：Nuclear medicine communications

authors： Kitajima K,Suzuki K,Senda M,Kita M,Nakamoto Y,Onishi Y,Maeda T,Yoshikawa T,Ohno Y,Sugimura K

更新日期：2011-07-01 00:00:00

abstract：:A new radiopharmaceutical, 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HM-PAO) is described. This agent displays considerable promise for imaging cerebral blood flow. In studies in rats and one human volunteer, 99Tcm-HM-PAO demonstrates good brain uptake, prolonged retention of activity in the brain, and slow regional...

journal_title：Nuclear medicine communications

authors： Holmes RA,Chaplin SB,Royston KG,Hoffman TJ,Volkert WA,Nowotnik DP,Canning LR,Cumming SA,Harrison RC,Higley B

更新日期：1985-08-01 00:00:00

abstract：:This article discusses the problems facing nuclear medicine in the coming decade and outlines the areas in which new developments or expansion can be expected. The questions considered include legislative requirements, the need to educate the public and the medical profession on the strengths of nuclear medicine, appr...

journal_title：Nuclear medicine communications

authors： Ell PJ

更新日期：1992-02-01 00:00:00

abstract：:The impact of recent advances in the chemical and genetic engineering manipulations of antibodies on radioimmunotargeting is reviewed both in relation to radioimmunoscintigraphy and radioimmunotherapy. The resulting trends are: (1) the linking of parts of the mouse/rat and human antibody molecule; (2) the creation of ...

journal_title：Nuclear medicine communications

authors： Hazra DK,Britton KE,Lahiri VL,Gupta AK,Khanna P,Saran S

更新日期：1995-02-01 00:00:00

abstract：:Comparisons of gastric emptying between different centres are difficult because of wide variations in methods. Reproducibility of a method is very important before it is used to compare different subjects or to assess the effect of treatment. The aim of this study was to measure the reproducibility of gastric emptying...

journal_title：Nuclear medicine communications

authors： Kong MF,Perkins AC,King P,Blackshaw PE,Macdonald IA

更新日期：1998-01-01 00:00:00

abstract：:We have assessed the usefulness of a radionuclide dilution method for estimation of ascitic fluid volume. 99Tc(m) macroaggregated albumin (10 MBq) was injected into the peritoneal fluid. Multiple samples were taken using a trocath peritoneal dialysis catheter over a 4-h period. Blood samples were taken at the same tim...

journal_title：Nuclear medicine communications

authors： Notghi A,Williams NR,Kehoe S,Smith NB,Harding LK

更新日期：2000-12-01 00:00:00

abstract：:Scintimammography is a recently verified technique that will expand the use of nuclear medicine to a new group of patients in whom scintigraphic imaging has not been widely used. If performed correctly, and in certain groups of patients, it delivers a sensitivity as high as X-ray mammography or magnetic resonance imag...

journal_title：Nuclear medicine communications

authors： Buscombe JR,Cwikla JB,Thakrar DS,Hilson AJ

更新日期：1997-08-01 00:00:00