Radioimmunolocalization and selective delivery of radiation in a rat model system: comparison of intact and fragmented antibody.

abstract：OBJECTIVES:N staging is a key factor when considering the choice of treatment for non-small-lung cancer. It is possible that there is a correlation between N2 metastasis and some risk factors. The objective of the present study was to evaluate associations between several risk factors and N(2) metastasis using univaria...

journal_title：Nuclear medicine communications

authors： Su M,Li Y,Li F,Li L,Tian R

更新日期：2014-09-01 00:00:00

abstract：:Radioiodinated meta-iodobenzylguanidine (MIBG) is used routinely for imaging and targeted radiotherapy of tumours derived from the neural crest. Since active uptake of MIBG by the noradrenaline transporter (NAT) makes a greater contribution to total drug accumulation than passive uptake when MIBG is present at low con...

journal_title：Nuclear medicine communications

authors： Owens J,Bolster AA,Prosser JE,Cunningham S,Mairs RJ,Neilly JB,Reed NS,Hilditch TE

更新日期：2000-05-01 00:00:00

abstract：:Bone scintigraphy has been shown to be sensitive in determining bone involvement in patients with malignancy, but it does not allow the assessment of bone marrow lesions in early disease. The aim of this study was to detect bone marrow invasion using 99Tcm-labelled monoclonal antigranulocyte antibody (AgMoAb) in patie...

journal_title：Nuclear medicine communications

authors： Kiraç S,Duman Y,Cüreklibatur I,Yüksel D,Nazli O,Günaydin G,Taner M

更新日期：1997-10-01 00:00:00

abstract：:Radioiodine therapy using oral administration of Iodine-131 (I) is a widespread employed strategy for the treatment of hyperthyroidism and thyroid cancer. Such a therapy requires well-trained staff, equipment and procedures regarding radiation safety. The aims of this work are to report an incidental experience of rad...

journal_title：Nuclear medicine communications

authors： Labbe E,Peyronnet D,Desmonts C,Vigne J

更新日期：2020-11-01 00:00:00

abstract：:The aim of the study was to evaluate pulmonary nodules (PNs) by incorporating time sensitivity (S) factor in the retention index (RI) and compare with the traditional fixed interval method. After obtaining approval from the Human Investigations Committee, 97 PNs from 81 patients (age=70±11) referred for dual-time fluo...

journal_title：Nuclear medicine communications

authors： Wong CY,Al-faham Z,Jolepalem P,Wong WW,Thie J

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the fraction of administered activity that was excreted and retained by a small cohort of patients who each received treatment with radium-223 dichloride (Ra). Ra is an α-emitting radionuclide that has been approved for use in the treatment of bone metastases that are sec...

journal_title：Nuclear medicine communications

authors： Pratt BE,Hindorf C,Chittenden SJ,Parker CC,Flux GD

更新日期：2018-02-01 00:00:00

abstract：:To evaluate the clinical utility of 123I-labelled 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (123I-BMIPP), myocardial scintigraphy using 123I-BMIPP was performed in 13 patients with hypertrophic cardiomyopathy (HCM), and the findings were compared with those of 201Tl. The uptake of each tracer was scored visual...

journal_title：Nuclear medicine communications

authors： Ohtsuki K,Sugihara H,Umamoto I,Nakamura T,Nakagawa T,Nakagawa M

更新日期：1994-06-01 00:00:00

abstract：:To evaluate the incidence, severity and clinical course of right ventricular (RV) involvement after acute inferior myocardial infarction (IMI), 78 patients (pts) with IMI were investigated by both 99Tcm-pyrophosphate (PYP) scan and gated blood pool scan (GBPS). GBPS was performed at admission and 10 days, whereas 99Tc...

journal_title：Nuclear medicine communications

authors： Nishimura T,Yasuda T,Gold HK,Leinbach RC,Boucher CA,McKusick KA,Strauss HW

更新日期：1986-12-01 00:00:00

abstract：AIM:In patients with differentiated thyroid carcinoma (DTC), metastases can either show iodine-131 (I) uptake on whole-body scintigraphy or F-2-fluoro-2-deoxy-D-glucose (F-FDG) uptake on combined PET and X-ray computed tomography (PET/CT), or a mix of both. The present study investigates the relationship between uptake...

journal_title：Nuclear medicine communications

authors： Kelders A,Kennes LN,Krohn T,Behrendt FF,Mottaghy FM,Verburg FA

更新日期：2014-02-01 00:00:00

abstract：:In this cross-sectional study, the relative importance of anthropometric factors and that of biological parameters on bone mineralization were evaluated and their practical implications inferred on the choice of the parameter to be used for the estimation of bone mineralization. A close relationship between anthropome...

journal_title：Nuclear medicine communications

authors： Rozenberg S,Ham H,Peretz A,Caufriez A,Bosson D,Robyn C

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:A lack of response to cardiac resynchronization therapy (CRT) has been reported in 20-40% of heart failure patients with left ventricular (LV) dyssynchrony who underwent treatment based on the established guidelines. The study aimed to investigate the relationship between (99m)Tc-tetrofosmin ((99m)Tc-TF) myoc...

journal_title：Nuclear medicine communications

authors： Shigeru M,Fujiwara S,Takamine S,Yoshida A,Kawai H,Shiotani H,Hirata K

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Paragangliomas are rare tumours of neural crest origin that express high levels of somatostatin receptor. Ga-68 DOTATATE PET/CT is a widely accepted method for imaging of neuroendocrine tumours. This study was performed to review a Ga-68 DOTATATE PET/CT patient database and to establish the impact of the moda...

journal_title：Nuclear medicine communications

authors： Skoura E,Priftakis D,Novruzov F,Caplin ME,Gnanasegaran G,Navalkissoor S,Bomanji J

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Determine the prevalence of benign indium-111 (In) pentetreotide uptake in the pancreatic head and determine if a semi-quantitative method can be used to differentiate physiologic from pathologic uptake. PATIENTS AND METHODS:Institutional Review Board-approved, HIPAA-compliant retrospective review of 197 som...

journal_title：Nuclear medicine communications

authors： Derakhshan JJ,Farwell MD

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Clinical studies in women using technetium-99m (Tc)-Bombesin have shown successful radionuclide imaging of breast tumours overexpressing gastrin-releasing peptide receptors (GRPRs). Recent studies have demonstrated that most breast tumours overexpress folate receptors (FRα). AIM:The aim of this work was to ...

journal_title：Nuclear medicine communications

authors： Aranda-Lara L,Ferro-Flores G,Ramírez Fde M,Ocampo-García B,Santos-Cuevas C,Díaz-Nieto L,Isaac-Olivé K

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate the role of F-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (CT) in the early postoperative staging of breast cancer and to document (18)F-FDG PET/CT-based stage alterations and any subsequent impact on management. MATERIALS AND METHODS:Between January 2009 and ...

journal_title：Nuclear medicine communications

authors： Sen F,Akpinar AT,Ogur U,Duman G,Tamgac F,Alper E

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Extramammary Paget's disease (EMPD) is rare, and limited data have been reported on the utilization of fluorine-18 fluorodeoxyglucose PET/computed tomography ((18)F-FDG PET/CT) in this disease. The aim of this study is to evaluate the role of (18)F-FDG PET/CT in the diagnosis and staging of EMPD. MATERIALS AND...

journal_title：Nuclear medicine communications

authors： Tian Y,Wu HB,Li DL,Li HS,Zhou WL,Wang QS

更新日期：2015-09-01 00:00:00

abstract：:In normal adults, the maintenance of phosphate balance involves the reabsorption of 85-90% of filtered phosphate by the proximal tubule. At a glomerular filtration rate (GFR) of 125 ml min-1 and a plasma phosphate concentration of 1.3 mmol l-1, the filtered phosphate is approximately 235 mmol day-1. Following intraven...

journal_title：Nuclear medicine communications

authors： Nair N,Mahadeo DS,Patel R

更新日期：1998-07-01 00:00:00

abstract：:The main aim of this study was to investigate the role of N-(2,4,6 trimethyl-3-bromophenylcarbamoylmethyl) iminodiacetic acid (IDA; Mebrofenin) scintigraphy in follow-up assessments of the biliary system in patients with cystic fibrosis associated liver disease. Fourteen patients from a study published in 1996 were re...

journal_title：Nuclear medicine communications

authors： Foster JA,Ramsden WH,Conway SP,Taylor JM,Etherington C

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:Sickle cell disease (SCD) is a common hematologic hereditary disorder characterized by vaso-occlusive episodes affecting multiple organs, and substantially alters renal structure and function. We aimed to evaluate the utility of renal scintigraphy and single photon emission computed tomography/computed tomograp...

journal_title：Nuclear medicine communications

authors： Ramos CD,Onusic DM,Brunetto SQ,Amorim BJ,Souza TF,Saad STO,Lima MDCL

更新日期：2019-11-01 00:00:00

abstract：:To study the accuracy of renal function quantification with 99Tcm-DMSA we compared DMSA renal uptake and creatinine clearance in 16 cases of children with single kidney. The age of the patients ranged from two months to fourteen years. Creatinine clearance was normalized to 1.73 m2. DMSA uptake was measured 7 h after ...

journal_title：Nuclear medicine communications

authors： Baillet G,Gagnadoux MF,De Vernejoul P,Broyer M

更新日期：1985-11-01 00:00:00

abstract：:Mammography is the screening test of choice for breast cancer. Its low specificity leads to a large number of unnecessary biopsies. Scintimammography, with either Tc-sestamibi (MIBI) or Tc-anti-carcinoembryonic antigen (CEA) Fab', has been proposed as a non-invasive test to lower the high false positive rate of mammog...

journal_title：Nuclear medicine communications

authors： Sanidas EE,Koukouraki S,Velidaki A,Manios A,Stathopoulos E,De Bree E,Kafousi M,Kodogiannis E,Karkavitsas N,Tsiftsis DD

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:Single-photon emission computed tomography ventilation/perfusion (SPECT V/Q) imaging is recommended both by the Society of Nuclear Medicine and by the European Association of Nuclear Medicine for the diagnosis of pulmonary embolism. However, respiratory motion produces image blurring and degradation of detai...

journal_title：Nuclear medicine communications

authors： Darwesh RM,Shin E,Morgan PS,Perkins AC

更新日期：2014-02-01 00:00:00

abstract：:The aim of this study was to ascertain whether knee SPET can localize lesion sites in patients with internal derangements of the knee. We performed knee SPET as a pre-arthroscopic examination in 63 consecutive patients. SPET imaging was performed with a triple-headed SPET camera 4 h after the injection of 99Tcm-methyl...

journal_title：Nuclear medicine communications

authors： So Y,Chung JK,Seong SC,Sohn YJ,Kang HS,Lee DS,Lee MC

更新日期：2000-01-01 00:00:00

abstract：:A method is described for studying protein kinetics in pleural effusions in humans. In 15 patients with pleural effusions from a variety of causes, protein inflow was monitored by measuring the rate of appearance in the effusion of the plasma protein transferrin, radiolabelled in vivo by intravenous injection of 113In...

journal_title：Nuclear medicine communications

authors： Smith MJ,Joseph J,Flatman WD,Basran GS

更新日期：1992-06-01 00:00:00

abstract：:The application of a Well-type germanium semiconductor detector creates new possibilities in erythrocyte survival studies. Using 51Cr, the effective dose equivalent in a standard procedure can be reduced from approximately 780 to 2 microSv. The properties of the detector, namely, high efficiency and high energy resolu...

journal_title：Nuclear medicine communications

authors： De Vries RA,Oldenburg SJ,Thelosen T,De Bruin M,Poortman J,Van de Wiel A

更新日期：1991-05-01 00:00:00

abstract：AIM:The aim of this study was to assess ablation outcome after a second ablation dose and compare the ablation rate after low and high reablation doses of iodine-131 ((131)I) after failure of the first ablation with 3700 MBq. PATIENTS AND METHODS:The study included 81 patients with papillary thyroid cancer; they faile...

journal_title：Nuclear medicine communications

authors： M El-Refaei S,W Yassin S,Salman K,Al Munshy T,Al-Ezzi M,M Al-Sayed Y,Abd Elkareem Husseni M

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of (99m)Tc-pamidronate ((99m)Tc-APD) against (99m)Tc-medronate ((99m)Tc-MDP) as a new bone-seeking agent using intact bone and fractured femur in a rat model. METHODS:(99m)Tc-APD was prepared by the stannous reduction method. Scintigraphic images were obtained at 2 h and 24 h after ...

journal_title：Nuclear medicine communications

authors： Kumar V,Kumar D,Howman-Giles RB,Little DG

更新日期：2007-02-01 00:00:00

abstract：:Medullary thyroid carcinoma (MTC) is a neuroendocrine tumour characterized by the production and secretion of calcitonin. MTC tumours may express functional somatostatin receptors (hSSTR). A significant proportion of hSSTR receptor-positive MTC tumours, including metastatic disease, may be visualized in vivo through 1...

journal_title：Nuclear medicine communications

authors： O'Byrne KJ,O'Hare N,Sweeney E,Freyne PJ,Cullen MJ

更新日期：1996-09-01 00:00:00

abstract：AIM:To report our data concerning the changes in post-stress and at-rest left ventricular ejection fraction and ventricular volumes in patients with thallium gated SPECT. METHODS:Post-stress and at-rest thallium gated SPECT was performed in 629 consecutive patients; left ventricular ejection fraction (LVEF), left vent...

journal_title：Nuclear medicine communications

authors： del Val Gómez M,Gallardo FG,San Martín MA,Garcia A,Terol I

更新日期：2005-07-01 00:00:00

abstract：INTRODUCTION:Bispecific monoclonal antibodies (bsMAbs) have been developed as a pretargeting tool to reduce background activity, thereby increasing target to background (T : B) ratios. To enhance visualization of small lesions in vivo, we have used the pretargeting approach of bsMAb and negatively charged polymers radi...

journal_title：Nuclear medicine communications

authors： Gada KS,Patil V,Panwar R,Majewski S,Tekabe Y,Khaw BA

更新日期：2011-12-01 00:00:00