Estimation of ascitic fluid volume using 99Tcm labelled macroaggregated albumin.

Abstract:

:We have assessed the usefulness of a radionuclide dilution method for estimation of ascitic fluid volume. 99Tc(m) macroaggregated albumin (10 MBq) was injected into the peritoneal fluid. Multiple samples were taken using a trocath peritoneal dialysis catheter over a 4-h period. Blood samples were taken at the same time and a 4-h urine collection was made during the study. At 4 h a controlled drainage of ascitic fluid, followed by suction drainage, was used and a total drained volume measured. For comparison, peritoneal volumes were measured from the radioactivity of peritoneal fluid activity samples using dilution techniques. The estimated peritoneal fluid volume using the radionuclide method was consistently higher than the drained volume. This was attributed to either a lack of uniform distribution of the activity in the peritoneal cavity by 4 h or early breakdown and absorption of activity from the peritoneal cavity. In two patients it was not possible to measure a volume due to poor distribution of the radionuclide in the peritoneal fluid. We found that in our group of patients the radionuclide dilution is of little value in estimating the peritoneal fluid volume.

journal_name

Nucl Med Commun

authors

Notghi A,Williams NR,Kehoe S,Smith NB,Harding LK

doi

10.1097/00006231-200012000-00009

keywords:

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

1153-6

issue

12

eissn

0143-3636

issn

1473-5628

journal_volume

21

pub_type

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