Relationship of alveolar permeability and lung inflammation in patients with active diffuse infiltrative lung disease detected by 99Tcm-DTPA radioaerosol inhalation lung scintigraphy and quantitative 67Ga lung scans.

Abstract:

:The alveolar permeability (AP) in 21 patients with active diffuse infiltrative lung disease (ILD) was measured by 99Tcm-diethylenetriaminapentaacetate (DTPA) radioaerosol inhalation lung scintigraphy. The degree of AP damage in ILD was presented as the slope (% min-1) of the time-activity curve from the dynamic lung image. Meanwhile, the quantitative Ga lung scan (GA) was performed as a Ga uptake index (GUI) to evaluate the severity of lung inflammation in active ILD. The results show that no good correlation between the degree of AP damage and lung inflammation was found. When the patients were divided into two groups of (A) eight active ILD with normal chest X-ray (X-ray) and (B) 13 active ILD with abnormal X-ray, there was no significant difference between groups A and B for the DTPA and Ga results. In conclusion, the relationship between the degree of AP damage and lung inflammation in active ILD is not significant. This was not consistent with X-ray findings. There was, however, a significant difference between those with ILD and normal controls.

journal_name

Nucl Med Commun

authors

Kao CH,Lin HT,Yu SL,Wang SJ,Yeh SH

doi

10.1097/00006231-199410000-00012

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

850-4

issue

10

eissn

0143-3636

issn

1473-5628

journal_volume

15

pub_type

杂志文章
  • Pentavalent 99Tcm-DMSA imaging in patients with bone metastases.

    abstract::Pentavalent 99Tcm-dimercaptosuccinic acid (99Tcm-(V)DMSA) has an established role in imaging medullary thyroid carcinoma. There have been case reports of uptake in bone metastases. Our aims were to compare 99Tcm-(V)DMSA with 99Tcm-hydroxymethylene diphosphonate (99Tcm-HDP) in bone metastases, to assess its value in im...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-199710000-00003

    authors: Lam AS,Kettle AG,O'Doherty MJ,Coakley AJ,Barrington SF,Blower PJ

    更新日期:1997-10-01 00:00:00

  • Multidose use of exametazine for leukocyte labelling: a new approach using tin enhancement.

    abstract::Reconstituted exametazime is inherently unstable due to the rapid oxidation of the small amount (7.6 micrograms) of stannous chloride present in the kit. A novel approach has been used to improve the shelf-life of reconstituted exametazime based on the premise that tin lost through oxidation should be replaced by furt...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199311000-00016

    authors: Solanki C,Li DJ,Wong A,Miles KA,Sampson CB

    更新日期:1993-11-01 00:00:00

  • An assessment of wall motion, perfusion and glucose metabolism in recent myocardial infarction: a comparison in patients with and without revascularization.

    abstract::The aim of this study was to compare the extent and severity of wall motion abnormalities, perfusion and glucose metabolism, in recent myocardial infarction in patients with and without revascularization. Forty-nine patients were studied (82% men; mean age 58 years) by using echocardiography, 201Tl single photon emiss...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200311000-00006

    authors: González P,Massardo T,Coll C,Redondo F,Yovanovich J,Jofré J,Chamorro H,Humeres P,Sierralta P,Ramírez A,Kunstmann S,López H,Aramburú I,Brugère S

    更新日期:2003-11-01 00:00:00

  • Reproducibility and repeatability of differential renal function in 4-week-old piglets.

    abstract:BACKGROUND:Congenital obstructive renal disease often requires a decision early in the child's life on whether or not surgery is required. Differential renal function (DRF) calculated from the renogram provides important information for the correct decision in this process. A recent publication cast doubt as to the rel...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e3282f20e1f

    authors: Dissing TH,Eskild-Jensen A,Pedersen M,Anderson PJ,Rittig N,Frøkiaer J,Gordon I

    更新日期:2008-01-01 00:00:00

  • Abdominal scintigraphy with 99Tcm-labelled red cells in the detection of rebleeding from peptic ulcers.

    abstract::The technique of 99Tcm-labelled red cell scintigraphy as a means of detecting rebleeding was investigated in 33 patients with bleeding peptic ulcers. Scintigrams were performed twice during the 24 h period succeeding diagnostic endoscopy. There was scintigraphic evidence of rebleeding in 23 patients but this was clini...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198509000-00003

    authors: Kinnear WJ,Dickinson RJ,Buxton-Thomas M,Wraight EP

    更新日期:1985-09-01 00:00:00

  • Normal distribution pattern and physiological variants of 68Ga-PSMA-11 PET/CT imaging.

    abstract:PURPOSE:Ga-PSMA-11 is a novel PET tracer suggested to be used for imaging of advanced prostate cancer. In this study, we aimed to present a detailed biodistribution of Ga-PSMA-11, including physiological and benign variants of prostate-specific membrane antigen (PSMA) imaging. MATERIALS AND METHODS:We carried out a re...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000566

    authors: Demirci E,Sahin OE,Ocak M,Akovali B,Nematyazar J,Kabasakal L

    更新日期:2016-11-01 00:00:00

  • Semi-quantitative assessment of 99Tcm-sestamibi uptake in lung cancer: relationship with clinical response to chemotherapy.

    abstract::The objectives of this study were to measure semi-quantitatively uptake of 99Tcm-sestamibi (99Tcm-MIBI) by tumour tissue in patients with lung cancer and to investigate its relationship with clinical response to chemotherapy. 99Tcm-MIBI single photon emission tomography was performed at the time of diagnosis in 31 pat...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199711000-00013

    authors: Ceriani L,Giovanella L,Bandera M,Beghe B,Ortelli M,Roncari G

    更新日期:1997-11-01 00:00:00

  • The role of 99mTc-labelled glucosamine (99mTc-ECDG) in the evaluation of rheumatic joint disease: a screening experience.

    abstract:OBJECTIVES:We investigated the localization pattern of a novel imaging agent, (99m)Tc-labelled glucosamine (ECDG), in a variety of rheumatic conditions. MATERIALS AND METHODS:Sixteen patients were recruited into the study, with either active rheumatoid arthritis or osteoarthritis. (99m)Tc-ECDG was prepared in-house an...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000096

    authors: Angelides S,El-Mashaleh M,Anagnostou M,Howe G,Spencer D,Kumar V,Manolios N

    更新日期:2014-06-01 00:00:00

  • The role of IDA scintigraphy in the follow-up of liver disease in patients with cystic fibrosis.

    abstract::The main aim of this study was to investigate the role of N-(2,4,6 trimethyl-3-bromophenylcarbamoylmethyl) iminodiacetic acid (IDA; Mebrofenin) scintigraphy in follow-up assessments of the biliary system in patients with cystic fibrosis associated liver disease. Fourteen patients from a study published in 1996 were re...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200207000-00012

    authors: Foster JA,Ramsden WH,Conway SP,Taylor JM,Etherington C

    更新日期:2002-07-01 00:00:00

  • Improved radiopharmaceutical based on 99mTc-Bombesin-folate for breast tumour imaging.

    abstract:BACKGROUND:Clinical studies in women using technetium-99m (Tc)-Bombesin have shown successful radionuclide imaging of breast tumours overexpressing gastrin-releasing peptide receptors (GRPRs). Recent studies have demonstrated that most breast tumours overexpress folate receptors (FRα). AIM:The aim of this work was to ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000460

    authors: Aranda-Lara L,Ferro-Flores G,Ramírez Fde M,Ocampo-García B,Santos-Cuevas C,Díaz-Nieto L,Isaac-Olivé K

    更新日期:2016-04-01 00:00:00

  • InfuShield: a shielded enclosure for administering therapeutic radioisotope treatments using standard syringe pumps.

    abstract::The administration of radionuclide therapies presents significant radiation protection challenges. The aim of this work was to develop a delivery system for intravenous radioisotope therapies to substantially moderate radiation exposures to staff and operators. A novel device (InfuShield) was designed and tested befor...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000634

    authors: Rushforth DP,Pratt BE,Chittenden SJ,Murray IS,Causer L,Grey MJ,Gear JI,Du Y,Flux GD

    更新日期:2017-03-01 00:00:00

  • [99Tcm]MAG3 gamma camera nephrography in epidemic nephritis.

    abstract::There is a lack of systematic nephrographic studies on epidemic nephritis (EN). We studied 10 patients with EN using [99Tcm]MAG3 gamma camera nephrography and followed up 9 of them 22-68 days later when they had clinically recovered. Variables for renal clearance of [99Tcm]MAG3 and the retention of radioactivity in th...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199101000-00003

    authors: Paul R,Kiiliäinen H,Tarssanen L,Vorne M

    更新日期:1991-01-01 00:00:00

  • Information for patients and staff concerning nuclear medicine.

    abstract::Providing information to patients and staff is an important part of the practice of nuclear medicine. To assist in improving the standard of communications, guidance has been prepared covering the content, style and presentation of letters and leaflets for patients and for medical and nursing staff. Examples are provi...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199204000-00159

    authors: Clarke SE,McKillop JH,Prescott MC,Williams ED

    更新日期:1992-04-01 00:00:00

  • Clinical competence in myocardial perfusion scintigraphic stress testing: general training guidelines and assessment.

    abstract::The suggestion by the National Institute for Clinical Excellence (NICE) to more than triple the number of myocardial perfusion scintigraphy (MPS) procedures carried out by the NHS each year is a challenge both in terms of numbers of gamma cameras available to carry out the scans and qualified staff to supervise stress...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,实务指引

    doi:10.1097/MNM.0b013e32818a6e72

    authors: Jones I,Latus K,Bartle L,Gardner M,Parkin V,Guideline Development and Writing Group, British Nuclear Medicine Society and British Nuclear Cardiac Society.

    更新日期:2007-07-01 00:00:00

  • Bone marrow scintigraphy in small cell carcinoma of the lung.

    abstract::A comparative study of bone marrow scintigraphy using 99Tcm-nanocolloid, conventional bone scintigraphy and bone marrow biopsy were performed in 35 patients with histologically proven small cell carcinoma of the lung to determine whether bone marrow scintigraphy has a role in the early detection of bone marrow metasta...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199401000-00006

    authors: Li DJ,Maughan TS,Miles KA,Wraight EP

    更新日期:1994-01-01 00:00:00

  • Detection of norepinephrine distribution in rats with adrenal medulla autotransplants using 125I-meta-iodobenzyl guanidine.

    abstract::The viability of autologous adrenal medullary transplants was evaluated using 125I-meta-iodobenzyl guanidine (MIBG), an adrenal medullary scanning agent. Bilateral cavities in the caudate nuclei were made stereotaxically in Wistar rats. One week later, the left adrenal medulla was resected by microsurgery, followed by...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199409000-00015

    authors: Shinoda M,Suzuki Y,Oi S,Tsugane R,Sato O

    更新日期:1994-09-01 00:00:00

  • 'Early' thyroid 123I uptake: correction for extrathyroidal neck radioactivity.

    abstract::Should one correct for extrathyroidal neck radioactivity ('neck background') when interpreting perchlorate discharge test results? A new background correction method was developed using a linear probe. 123I produces photon peaks at two energy levels: 159 keV (gamma-rays) and 28 keV (X-rays), with an attenuation of 15 ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199211000-00013

    authors: Arntzenius AB,van der Heide D,Meinders AE

    更新日期:1992-11-01 00:00:00

  • Are there normal values of phase analysis parameters for left ventricular dyssynchrony in patients with no structural cardiomyopathy?: a systematic review.

    abstract:BACKGROUND:ECG-gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy combined with phase analysis allows for the assessment of left ventricular dyssynchrony. However, there are several software programs available thereby introducing variability in outcome and normal values. The aim ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001068

    authors: Marques de Souza Filho E,Tinoco Mesquita C,Altenburg Gismondi R,de Amorim Fernandes F,Jan Verberne H

    更新日期:2019-10-01 00:00:00

  • 74 MBq radioiodine 131I does not prevent uptake of therapeutic doses of 131I (i.e. it does not cause stunning) in differentiated thyroid cancer.

    abstract::Altogether, 147 scintiscans, completed 48-72 h after 74 MBq 131I, were compared with scintiscans obtained on average 7.8 days after therapeutic doses of 131I. The therapeutic doses ranged from 1100 to just over 7400 MBq. The reasons for the investigation were to determine (1) if the diagnostic dose interfered with upt...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199706000-00002

    authors: McDougall IR

    更新日期:1997-06-01 00:00:00

  • Impact of fluorodeoxyglucose PET on the management of esophageal cancer.

    abstract::Esophageal cancer is the third most common malignancy of the alimentary tract. The incidence of esophageal cancer has steadily increased over the past three decades. Almost all therapeutic modalities for esophageal cancer are associated with a considerable mortality and morbidity. Consequently, there has been growing ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,评审

    doi:10.1097/MNM.0b013e32831af204

    authors: Salavati A,Basu S,Heidari P,Alavi A

    更新日期:2009-02-01 00:00:00

  • 18F-Fluorodeoxyglucose PET/CT and dynamic contrast-enhanced MRI as imaging biomarkers in malignant pleural mesothelioma.

    abstract:PURPOSE:The purpose of this study was to compare the use of fluorine-18-fluorodeoxyglucose (F-FDG) PET with computed tomography (CT) and dynamic contrast-enhanced (DCE) MRI to predict prognosis and monitor treatment in malignant pleural mesothelioma. PATIENTS AND METHODS:F-FDG PET/CT and DCE-MRI studies carried out as...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0000000000000789

    authors: Hall DO,Hooper CE,Searle J,Darby M,White P,Harvey JE,Braybrooke JP,Maskell NA,Masani V,Lyburn ID

    更新日期:2018-02-01 00:00:00

  • Background in 99Tcm DTPA renography evaluated by the impact of its components on individual kidney glomerular filtration rate.

    abstract::Following injection for renography, 99Tcm-labelled diethylenetriamine-pentacetic acid (DTPA) rapidly enters the extravascular space. Background therefore comprises two components, a falling intravascular signal and an extravascular signal which initially rises. We estimated the relative magnitudes of these two compone...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198808000-00003

    authors: Peters AM,Gordon I,Evans K,Todd-Pokropek A

    更新日期:1988-08-01 00:00:00

  • Extraction of arterial input function for measurement of brain perfusion index with 99mTc compounds using fuzzy clustering.

    abstract::Cerebral blood flow (CBF) can be quantified non-invasively using the brain perfusion index (BPI) determined from radionuclide angiographic data generated with 99mTc-hexamethylpropylene amine oxime (99mTc-HMPAO). When measuring the BPI, manual drawing of regions of interest (ROIs) (manual ROI method) for the extraction...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200403000-00014

    authors: Murase K,Nagayoshi M,Uenishi Y,Kawamata M,Yamazaki Y,Takasawa M,Oku N,Hatazawa J

    更新日期:2004-03-01 00:00:00

  • Cytotoxicity of 213Bi- and 225Ac-immunoconjugates.

    abstract::This paper describes in vitro cytotoxicity experiments with 213Bi- and 225Ac-immunoconjugates on the human epidermoid tumour cell line A431 using a blood group A-reactive murine IgG (2D11) as the specific antibody and MOPC 21 as the control antibody. With both radionuclides, specific cell-killing was achieved. The obs...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199506000-00009

    authors: Kaspersen FM,Bos E,Doornmalen AV,Geerlings MW,Apostolidis C,Molinet R

    更新日期:1995-06-01 00:00:00

  • Morphine-augmented hepatobiliary scintigraphy: a meta-analysis.

    abstract::The aim of this study was to compare the sensitivity and specificity of morphine-augmented hepatobiliary scintigraphy (MA-HBS) with that of conventional hepatobiliary scintigraphy (C-HBS) for acute cholecystitis. The results of most MA-HBS studies cannot be compared with C-HBS estimates, since articles describing C-HB...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199512000-00013

    authors: Cabana MD,Alavi A,Berlin JA,Shea JA,Kim CK,Williams SV

    更新日期:1995-12-01 00:00:00

  • Wipe tests to assess 99Tcm surface contamination: effects of surface type, swab type and chemical form.

    abstract::The efficacy of wipe tests for assessing 99Tcm surface contamination was measured. Four types of surface were contaminated with four radiopharmaceuticals and wiped using four types of swab. The fraction of activity removed was measured by direct monitoring for each combination of surface, pharmaceutical and swab. The ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199102000-00005

    authors: Scott LE,Gibson CJ

    更新日期:1991-02-01 00:00:00

  • Non-invasive quantification of cerebral blood flow for rats by microPET imaging of 15O labelled water: the application of a cardiac time-activity curve for the tracer arterial input function.

    abstract:OBJECTIVE:In-vivo quantitative cerebral blood flow (CBF) measurement using positron emission tomography (PET) has typically employed invasive arterial blood sampling procedure to determine the arterial input function (AIF). The present study was performed to provide a non-invasive quantitative CBF measurement technique...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200510000-00009

    authors: Yee SH,Jerabek PA,Fox PT

    更新日期:2005-10-01 00:00:00

  • Prognostic value of neutrophil-to-lymphocyte ratio and its correlation with fluorine-18-fluorodeoxyglucose metabolic parameters in intrahepatic cholangiocarcinoma submitted to 90Y-radioembolization.

    abstract:OBJECTIVE:The aim of this study was to investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) and its relationship with several metabolic parameters obtained through PET in intrahepatic cholangiocarcinoma (ICC) submitted to radioembolization with Y-microspheres (Y-radioembolization). METHODS:Records ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001123

    authors: Filippi L,Di Costanzo GG,Tortora R,Pelle G,Saltarelli A,Marino Marsilia G,Cianni R,Schillaci O,Bagni O

    更新日期:2020-01-01 00:00:00

  • Scintigraphic assessments of the reparative process in osteonecrosis of the femoral head using SPECT/CT with 99mTc hydroxymethylene diphosphonate.

    abstract:OBJECTIVE:The aim of the study was to assess the degree and location of the reparative process in early osteonecrosis of the femoral head on the basis of single-photon emission computed tomography/computed tomography (SPECT/CT) with technetium-99m hydroxymethylene diphosphonate. MATERIALS AND METHODS:This study was ap...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000166

    authors: Motomura G,Yamamoto T,Abe K,Nakashima Y,Ohishi M,Hamai S,Doi T,Honda H,Iwamoto Y

    更新日期:2014-10-01 00:00:00

  • Influence of early (F+0) intravenous furosemide injection on the split renal function using 99mTc-DTPA renography.

    abstract::In busy nuclear medicine departments, the F+0 protocol for diuretic renography is routinely used to shorten the acquisition time. The aim of this study was to evaluate the influence of the F+0 protocol on the split renal function (SRF) during a dynamic renal scan using technetium-99m diethylene triamine pentaacetic ac...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32835e7437

    authors: Kandeel AA,Elhossainy SA,Elsayed ND

    更新日期:2013-04-01 00:00:00