Cytotoxicity of 213Bi- and 225Ac-immunoconjugates.

abstract：:This study combines the pharmacologically-induced penile erection (PIPE) technique with radionuclide phallography (RNP) for the non-invasive study of penile haemodynamic changes during erection. Penile erections produced by the intracavernosal injections of two different vasoactive drugs, prostaglandin E1 (PGE1) and p...

journal_title：Nuclear medicine communications

authors： Siraj QH,Bomanji J,Akhtar MA,Rana MH,Sadiq M,Ahmed M

更新日期：1990-06-01 00:00:00

abstract：INTRODUCTION:In the present study, (99m)Tc-radiolabelled E-selectin binding peptide ((99m)Tc-IMP-178) was investigated for its potential to image acute pyogenic osteomyelitis in a new animal model. Intraindividual comparisons were performed using an irrelevant peptide ((99m)Tc-IMP-100) to demonstrate specificity. METH...

journal_title：Nuclear medicine communications

authors： Gratz S,Béhé M,Boerman OC,Kunze E,Schulz H,Eiffert H,O'Reilly T,Behr TM,Angerstein C,Nebendahl K,Kauer F,Becker W

更新日期：2001-09-01 00:00:00

abstract：:Published values of tissue weighting factors for adolescents and children derived from the life-span study of the atomic bomb survivors have been used to calculate the effective dose to patients aged 1, 5, 10 and 15 years undergoing a common paediatric procedure requiring one of the following radiopharmaceuticals: 99T...

journal_title：Nuclear medicine communications

authors： Gadd R,Mountford PJ,Oxtoby JW

更新日期：1999-06-01 00:00:00

abstract：:A number of authors have indicated a more sensitive detection of renal cortical defects using single photon emission tomography (SPET) compared with planar imaging when performing 99Tcm-dimer-captosuccinic acid (99Tcm-DMSA) renal scintigraphy. The place of SPET in the evaluation of kidneys in adults suspected of acute...

journal_title：Nuclear medicine communications

authors： Everaert H,Flamen P,Franken PR,Peeters P,Bossuyt A,Piepsz A

更新日期：1996-10-01 00:00:00

abstract：:We performed in vitro aggregation and indium-111 labeled platelet kinetic and biodistribution studies in seven patients with diabetes mellitus and in five control subjects. All subjects were male. All diabetic patients were poorly controlled at the time of study with blood glucose greater than 140 mg % and hemoglobin ...

journal_title：Nuclear medicine communications

authors： Luikens B,Forstrom LA,Johnson T,Johnson G

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Brain metastases are common in lung cancer. Whole-body 2-deoxy-2-[fluorine-18]fluoro-D-glucose ([F]FDG) PET/computed tomography (CT) is used for general staging, but MRI is the best modality for characterizing brain abnormalities. We aimed to determine whether PET/CT is suitable for selecting patients for MRI...

journal_title：Nuclear medicine communications

authors： Hjorthaug K,Højbjerg JA,Knap MM,Tietze A,Haraldsen A,Zacho HD,Kramer SM,Borghammer P

更新日期：2015-11-01 00:00:00

abstract：:The blood flow in renal transplants can be represented by (1) a K/A ratio, the ratio of the slopes of the ascending part of the renal perfusion curve and the arterial curve, (2) a perfusion index, the ratio of a part of the area under the first-pass arterial curve and renal curve, and (3) a height ratio, the ratio of ...

journal_title：Nuclear medicine communications

authors： Groothedde RT,Koppejan LJ,Heidendal GK,Hasman A

更新日期：1990-11-01 00:00:00

abstract：AIM:To develop a strategy for checking the reliability of slope intercept measurement of glomerular filtration rate (GFR). METHODS:Six blood samples, obtained bilaterally 20-240 min after the injection of Cr-ethylenediaminetetraacetic acid (EDTA) and iohexol into opposite arms, were assayed for indicator injected cont...

journal_title：Nuclear medicine communications

authors： Bird NJ,Peters C,Michell AR,Peters AM

更新日期：2008-12-01 00:00:00

abstract：:N-isopropyl-p-I-123-iodoamphetamine (123I-IMP) is extracted by the brain in proportion to regional blood flow. It is particularly useful in the clinical assessment of various pathological conditions related to altered cerebral flow. Moreover, it has been reported that 123I-IMP is avidly incorporated into melanin and m...

journal_title：Nuclear medicine communications

authors： Watanabe N,Seto H,Yokoyama K,Matsuda H,Shimizu M,Tonami N,Hisada K,Kakishita M

更新日期：1996-02-01 00:00:00

abstract：:Radiation doses to the family and general public from 131I therapy of outpatients were assessed for comparison with the 1990 International Commission on Radiation Protection (ICRP) dose limits. Doses to family members of such patients, measured by previous workers, were converted to show that on average 5.6 +/- 3.7 mi...

journal_title：Nuclear medicine communications

authors： Wasserman HJ,Klopper JF

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:We investigated the role of Ga-68 DOTATATE PET/CT in comparison to F-18 FDG PET/CT in patients with low and intermediate versus high-grade neuroendocrine tumors (NETs). METHODS:We identified 81 patients who underwent Ga-68 DOTATATE PET/CT at our institution between May 2017 and December 2018 and met inclusio...

journal_title：Nuclear medicine communications

authors： You H,Kandathil A,Beg M,De Blanche L,Kazmi S,Subramaniam RM

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the accuracy of the sequential multiphase and dual-tracer (SMADT) technique utilizing technetium-99m pertechnetate (99mTcO4) and dynamic technetium-99m-2-methoxyisobutylisonitrile (99mTc-MIBI) with single-photon emission computed tomography/computed tomography (SPECT/CT) f...

journal_title：Nuclear medicine communications

authors： Berner AM,Haroon A,Nowosinska E,Offiah C,Luqman M,Newell M,Jan H

更新日期：2015-01-01 00:00:00

abstract：:Monoclonal antibody (MoAb) fragments are known to have advantages over intact immunoglobulins for radioimmunoscintigraphy. It is less clear whether they are as effective in the delivery of radioimmunotherapy. The imaging and dosimetric properties of an intact MoAb, K-1-21, reactive against human kappa light chains (LC...

journal_title：Nuclear medicine communications

authors： Walker KZ,Seymour-Munn K,Towson JE,Axiak SM,Raison RL,Bautovitch GJ,Morris J,Basten A

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the fraction of administered activity that was excreted and retained by a small cohort of patients who each received treatment with radium-223 dichloride (Ra). Ra is an α-emitting radionuclide that has been approved for use in the treatment of bone metastases that are sec...

journal_title：Nuclear medicine communications

authors： Pratt BE,Hindorf C,Chittenden SJ,Parker CC,Flux GD

更新日期：2018-02-01 00:00:00

abstract：:A postal survey of UK nuclear medicine departments was undertaken to collate information on equipment, numbers of procedures and staffing levels for the years 1992 and 1993. It was estimated that there are 235 sites undertaking nuclear medicine, the total number of procedures performed being some 490,000 in 1993 compa...

journal_title：Nuclear medicine communications

authors： Elliott AT,Elliott FM,Shields RA

更新日期：1996-01-01 00:00:00

abstract：:The standard nuclear medicine textbooks describe the pyramidal lobe of the thyroid as arising from the upper part of the thyroid lobes. Anatomy and surgical texts however describe it as a thyroglossal tract remnant and state that it arises from the isthmus. Review of 150 thyroid scintigrams confirms that on scintigrap...

journal_title：Nuclear medicine communications

authors： Savage PE,Khan O,Grover S,Ott R,McCready VR

更新日期：1984-03-01 00:00:00

abstract：:Marked changes in cardiac function have been noted in patients with hyperthyroidism or hypothyroidism due both to changes in sympathetic system function and to biochemical modifications of myocardial tissue. Metaiodobenzylguanidine (MIBG), an analogue of norepinephrine, can be used to evaluate myocardial sympathetic t...

journal_title：Nuclear medicine communications

authors： Maini CL,Tofani A,Sciuto R,Ferraironi A,Festa A,Rea S

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:(68)Ga-Dotatoc has become the PET radiopharmaceutical of choice for the diagnosis and treatment follow-up of neuroendocrine tumours. (68)Ga-Dotatoc is prepared on-site through a so-called magisterial preparation. The use of an appropriate buffer during the radiolabelling step is essential to maximize the lab...

journal_title：Nuclear medicine communications

authors： Bauwens M,Chekol R,Vanbilloen H,Bormans G,Verbruggen A

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:A lack of response to cardiac resynchronization therapy (CRT) has been reported in 20-40% of heart failure patients with left ventricular (LV) dyssynchrony who underwent treatment based on the established guidelines. The study aimed to investigate the relationship between (99m)Tc-tetrofosmin ((99m)Tc-TF) myoc...

journal_title：Nuclear medicine communications

authors： Shigeru M,Fujiwara S,Takamine S,Yoshida A,Kawai H,Shiotani H,Hirata K

更新日期：2014-09-01 00:00:00

abstract：:Foot problems are common causes of disability in diabetic patients with as many as 25% expected to develop severe foot or leg problems during their lifetimes. Although skin ulceration is the most frequent problem, bones may also be involved in two different clinical conditions: osteomyelitis and Charcot osteoarthropat...

journal_title：Nuclear medicine communications

authors： Giurato L,Uccioli L

更新日期：2006-09-01 00:00:00

abstract：:The aim of this study was to compare the extent and severity of wall motion abnormalities, perfusion and glucose metabolism, in recent myocardial infarction in patients with and without revascularization. Forty-nine patients were studied (82% men; mean age 58 years) by using echocardiography, 201Tl single photon emiss...

journal_title：Nuclear medicine communications

authors： González P,Massardo T,Coll C,Redondo F,Yovanovich J,Jofré J,Chamorro H,Humeres P,Sierralta P,Ramírez A,Kunstmann S,López H,Aramburú I,Brugère S

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...

journal_title：Nuclear medicine communications

authors： Cohen JB,Kalinyak JE,McDougall IR

更新日期：2004-02-01 00:00:00

abstract：:Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to evaluate squamous carcinoma (SCC) of the head and neck. This study evaluated the pharmacokinetics and biodistribution of 99Tcm(V)DMSA in patients with SCC and calculated the bone mass of a New Zealand White (N...

journal_title：Nuclear medicine communications

authors： Watkinson JC,Allen S,Lazarus CR,Sinclair J,Blake GM,Clarke SE

更新日期：1990-05-01 00:00:00

abstract：:Dual-isotope studies using 123I and 201Tl allow the assessment of sympathetic reinnervation in patients following heart transplantation. 123I-meta-iodobenzyl guanidine (123I-MIBG) serves as a tracer of the integrity of the sympathetic nervous system. 201Tl is used for landmarking to allow better delineation of the myo...

journal_title：Nuclear medicine communications

authors： Krause BJ,Gürtner C,Kranert WT,Maul FD,Baum RP,Hör G

更新日期：1995-08-01 00:00:00

abstract：AIM:The first pathogenetic step in multiple myeloma is the emergence of a limited number of clonal plasma cells, clinically known as monoclonal gammopathy of undetermined significance (MGUS). Patients with MGUS do not have symptoms or end-organ damage but they do have a 1% annual risk of progression to multiple myeloma...

journal_title：Nuclear medicine communications

authors： Giovanella L,Taborelli M,Ceriani L,Zucca E,Cavalli F,Delaloye AB

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Large-scale clinical trials have demonstrated that beta blocker therapy improves the prognosis of dilated cardiomyopathy (DCM), but cardiac events sometimes occur even in patients showing favourable response to the therapy. In this study, the usefulness of meta-iodobenzyguanidine (MIBG) in predicting cardiac ...

journal_title：Nuclear medicine communications

authors： Fujimoto S,Inoue A,Hisatake S,Yamashina S,Yamashina H,Nakano H,Yamazaki J

更新日期：2005-02-01 00:00:00

abstract：PURPOSE:The present study evaluated the usefulness of postoperative fluorine-18 fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) in the management of olfactory neuroblastoma (ONB). MATERIALS AND METHODS:Ten patients (eight men and two women; mean age, 48.5 years) with histologically confirmed ONB who underwent ...

journal_title：Nuclear medicine communications

authors： Fujioka T,Toriihara A,Kubota K,Machida Y,Nakamura S,Kishimoto S,Ohashi I,Shibuya H

更新日期：2014-08-01 00:00:00

abstract：:Radioactive tracer techniques using 131I- and 125I-insulin have been applied to study insulin metabolism. A simple method to label human insulin with 123I to a high specific activity is described. We have used this radiotracer to study insulin kinetics in vivo in normal subjects and in two groups of diabetic patients....

journal_title：Nuclear medicine communications

authors： Sinclair AJ,Signore A,Bomanji J,Britton KE,Pozzilli P,Gale EA

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Measurement errors occurring during glomerular filtration rate (GFR) studies propagate to an error in the calculated GFR. Previous work has modelled measurement errors for slope-intercept (SI-GFR), single-sample (SS-GFR) and slope-only (SO-GFR) methods. In this study, we have extended these models. The prima...

journal_title：Nuclear medicine communications

authors： Holness JL,Fleming JS,Chirehwa MT,Warwick JM

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Radium-223 was a treatment approved for patients with metastatic castrate-resistant prostate cancer, symptomatic bone metastases and no-visceral metastases, in progression after at least two prior lines of systemic therapy, or ineligible for any available systemic treatment. The aim of this study was to prov...

journal_title：Nuclear medicine communications

authors： Gazzilli M,Durmo R,Cossalter E,Cerudelli E,Panarotto MB,Albano D,Bertagna F,Giubbini R

更新日期：2020-04-01 00:00:00