Pharmacokinetics, biodistribution and dosimetry of 99Tcm(V)DMSA in humans with squamous cell carcinoma.

abstract：OBJECTIVES:Radioiodine ablation of thyroid tissue remains the cornerstone of treatment for patients with differentiated thyroid carcinoma after thyroidectomy. Selecting an optimal dose of radioiodine for successful ablation is a continuous challenge in these patients. METHODS:We compared the treatment response of 341 ...

journal_title：Nuclear medicine communications

authors： Fallahi B,Beiki D,Takavar A,Fard-Esfahani A,Gilani KA,Saghari M,Eftekhari M

更新日期：2012-03-01 00:00:00

abstract：:The combined use of 123I-BMIPP and 99Tcm-MIBI SPET imaging has been proposed as an alternative to PET for the non-invasive detection of jeopardized myocardium after a myocardial infarction, a mismatch accurately indicating jeopardized but still viable tissue. In this paper, a new quantitative approach is described, ex...

journal_title：Nuclear medicine communications

authors： Hambÿe AS,Dobbeleir A,Franken PR

更新日期：1997-12-01 00:00:00

abstract：:Scintigraphically, Warthin's tumour usually demonstrates increased tracer uptake compared to normal adjacent salivary tissue. A case is presented in which tumour uptake is no greater than the normal adjacent gland. Gustatory stimulation results in failure of tumour tracer washout, and this finding rather than 'hot' sa...

journal_title：Nuclear medicine communications

authors： Blue PW

更新日期：1988-06-01 00:00:00

abstract：:The suggestion by the National Institute for Clinical Excellence (NICE) to more than triple the number of myocardial perfusion scintigraphy (MPS) procedures carried out by the NHS each year is a challenge both in terms of numbers of gamma cameras available to carry out the scans and qualified staff to supervise stress...

journal_title：Nuclear medicine communications

authors： Jones I,Latus K,Bartle L,Gardner M,Parkin V,Guideline Development and Writing Group, British Nuclear Medicine Society and British Nuclear Cardiac Society.

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:Maximum standardized uptake value (SUV(max)) is a marker of tumor glucose metabolism detected by [(18)F]-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (PET/CT) and reflects tumor aggressiveness. The aim of the study was to evaluate the value of SUV(max) in differentiating benign from malignant solit...

journal_title：Nuclear medicine communications

authors： Hu SL,Yang ZY,Zhou ZR,Yu XJ,Ping B,Zhang YJ

更新日期：2013-06-01 00:00:00

abstract：:The time course of thyroglobulin (Tg) was monitored in patients with differentiated thyroid carcinoma after ablative therapy (thyroidectomy + 131I-treatment) with particular respect to endogeneous antibodies (Tg-ABs). In 232 patients (196 without Tg-ABs, 36 with Tg-ABs at the time of treatment) a sensitivity of 88% (a...

journal_title：Nuclear medicine communications

authors： Moser E,Braun S,Kirsch CM,Kleinhans E,Buell U

更新日期：1984-05-01 00:00:00

abstract：:Positron emission tomography (PET) is increasingly used clinically to provide functional information on disease processes, especially in oncology using the glucose analogue 2-[18F]fluoro-2-deoxy-D-glucose (F-FDG). In the clinical setting it has become standard practice to use simplified imaging protocols compared to t...

journal_title：Nuclear medicine communications

authors： Hallett WA

更新日期：2004-07-01 00:00:00

abstract：:In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

journal_title：Nuclear medicine communications

authors： Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

更新日期：1989-11-01 00:00:00

abstract：:Pentavalent 99Tcm-dimercaptosuccinic acid (99Tcm-(V)DMSA) has an established role in imaging medullary thyroid carcinoma. There have been case reports of uptake in bone metastases. Our aims were to compare 99Tcm-(V)DMSA with 99Tcm-hydroxymethylene diphosphonate (99Tcm-HDP) in bone metastases, to assess its value in im...

journal_title：Nuclear medicine communications

authors： Lam AS,Kettle AG,O'Doherty MJ,Coakley AJ,Barrington SF,Blower PJ

更新日期：1997-10-01 00:00:00

abstract：:Three ligand assays for TSH using monoclonal antibodies, an IRMA, an ELISA and a DELFIA were compared with a standard DAB RIA technique. The IRMA proved to be superior in respect to sensitivity, precision, reproducibility and practicality. The highest sensitivity yet, was achieved by DELFIA. IRMA, ELISA and DELFIA are...

journal_title：Nuclear medicine communications

authors： Böttger I,Pabst HW,Senekowitsch R,Kriegel H

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVE:To determine whether any patient or hepatic tumor characteristics are predictive of hepatopulmonary shunt fraction when performed before radioembolization. MATERIALS AND METHODS:A retrospective review was performed on 190 patients who underwent preradioembolization hepatic arteriography with calculation of h...

journal_title：Nuclear medicine communications

authors： Yerubandi V,Ronald J,Howard BA,Suhocki PV,James OG,Wong TZ,Kim CY

更新日期：2016-09-01 00:00:00

abstract：:The aim of this study was to examine the value of an additional atropine injection in patients who do not achieve an adequate heart rate during dobutamine infusion for myocardial perfusion SPET (single photon emission tomography). Patients undergoing dobutamine myocardial SPET who failed to achieve > or = 85% of their...

journal_title：Nuclear medicine communications

authors： Caner B,Karanfil A,Uysal U,Tokgozoglu L,Aksoyek S,Ugur O,Ciftci I,Atalar E,Kes S,Bekdik C

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Clinical studies in women using technetium-99m (Tc)-Bombesin have shown successful radionuclide imaging of breast tumours overexpressing gastrin-releasing peptide receptors (GRPRs). Recent studies have demonstrated that most breast tumours overexpress folate receptors (FRα). AIM:The aim of this work was to ...

journal_title：Nuclear medicine communications

authors： Aranda-Lara L,Ferro-Flores G,Ramírez Fde M,Ocampo-García B,Santos-Cuevas C,Díaz-Nieto L,Isaac-Olivé K

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the evolution of patients with internal mammary chain (IMC) drainage whether the IMC-sentinel lymph node (IMC-SLN) was biopsied or not, as well as to determine the clinical implications of the biopsy of the IMC-SLN (IMC-SLNB) in patients with breast cancer and IMC drainag...

journal_title：Nuclear medicine communications

authors： Domènech-Vilardell A,Bajén MT,Benítez AM,Ricart Y,Mora J,Rodríguez-Bel L,García-Tejedor A,Climent J,López-Ojeda A,Urruticoechea A,Martín-Comín J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:We retrospectively investigated the value of dynamic Tc-diisopropyl-iminodiacetic acid hepatobiliary scintigraphy (HBS) in discriminating postsurgical complications following liver transplantation (LT). METHODS:Dynamic HBS was performed for suspected post-LT complications in 201 cases. Hepatic uptake and exc...

journal_title：Nuclear medicine communications

authors： Lee JY,Hu W,Lee KH,Kwon CH,Lee EJ,Choi JY,Kim BT

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate the role of F-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (CT) in the early postoperative staging of breast cancer and to document (18)F-FDG PET/CT-based stage alterations and any subsequent impact on management. MATERIALS AND METHODS:Between January 2009 and ...

journal_title：Nuclear medicine communications

authors： Sen F,Akpinar AT,Ogur U,Duman G,Tamgac F,Alper E

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The widely applied F-FDG is known for its disadvantage in brain tumour PET imaging because of its high background uptake. C-choline can achieve high contrast of brain tumour imaging and was expected to have higher sensitivity and specificity. We analysed the misdiagnoses in C-choline PET imagin...

journal_title：Nuclear medicine communications

authors： Huang Z,Zuo C,Guan Y,Zhang Z,Liu P,Xue F,Lin X

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The new anti-cancer drug imatinib mesylate inhibits the tyrosine kinase growth factor receptor, c-KIT, and has shown spectacular activity in patients with gastrointestinal stromal tumours (GISTs). OBJECTIVE:To assess whether fluorodeoxyglucose positron emission tomography (FDG PET) is suitable for response ...

journal_title：Nuclear medicine communications

authors： Jager PL,Gietema JA,van der Graaf WT

更新日期：2004-05-01 00:00:00

abstract：:An increased uptake of bone-seeking radiopharmaceuticals into malignant bone lesions could further improve the diagnostic accuracy of routine bone scanning. The tracers used in clinical routine for bone scanning are methylene-diphosphonate (MDP), dicarboxypropane-diphosphonate (DPD) and ethylenediaminetetramethylene-p...

journal_title：Nuclear medicine communications

authors： Fueger BJ,Mitterhauser M,Wadsak W,Ofluoglu S,Traub T,Karanikas G,Dudczak R,Pirich C

更新日期：2004-04-01 00:00:00

abstract：:This study surveyed practice in nuclear cardiology in the UK in 1994. A questionnaire was sent to 219 centres performing nuclear imaging asking for details of current practice in nuclear cardiology. Replies were received from 192 centres (88%). Activity in performance of myocardial perfusion imaging (MPI) and radionuc...

journal_title：Nuclear medicine communications

authors： Pennell DJ,Prvulovich E,Tweddel A,Caplin J

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVES:Computed tomography (CT) automatic exposure control (AEC) systems are now used in all modern PET-CT scanners. A collaborative study was undertaken to compare AEC techniques of the three major PET-CT manufacturers for fluorine-18 fluorodeoxyglucose half-body oncology imaging. MATERIALS AND METHODS:An audit o...

journal_title：Nuclear medicine communications

authors： Iball GR,Tout D

更新日期：2014-04-01 00:00:00

abstract：:The aim of this study was to compare dual-isotope (99Tc(m) and 201Tl) SPET imaging with computed tomography (CT) and magnetic resonance imaging (MRI) in the differentiation of various lesions of the major salivary glands. Twenty-two patients underwent dual-isotope SPET imaging, of whom 12 also had CT and 15 also had a...

journal_title：Nuclear medicine communications

authors： Arbab AS,Koizumi K,Toyama K,Nambu A,Ichikawa T,Arai T,Araki T

更新日期：2000-03-01 00:00:00

abstract：:The requirements, problems and progress of radioimmunotherapy in the management of certain malignancies are described. The future prospects using a two- or three-stage approach are promising. ...

journal_title：Nuclear medicine communications

authors： Britton KE,Mather SJ,Granowska M

更新日期：1991-04-01 00:00:00

abstract：:Reticuloendothelial system (RES) phagocytic function or capacity can be measured by clearance studies with test substances. This study in the rat examines three commercially available 99Tcm-labelled test substances, and different methods of calculating RES capacity. Albures size 500 nm and sulphur colloid size 600 nm ...

journal_title：Nuclear medicine communications

authors： Holmberg SB,Hafström L,Jacobsson L

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of (99m)Tc-pamidronate ((99m)Tc-APD) against (99m)Tc-medronate ((99m)Tc-MDP) as a new bone-seeking agent using intact bone and fractured femur in a rat model. METHODS:(99m)Tc-APD was prepared by the stannous reduction method. Scintigraphic images were obtained at 2 h and 24 h after ...

journal_title：Nuclear medicine communications

authors： Kumar V,Kumar D,Howman-Giles RB,Little DG

更新日期：2007-02-01 00:00:00

abstract：:Forty-four patients with symptoms of lower limb arterial insufficiency were examined by radionuclide angiography using 99Tcm in vivo red cell labelling and by contrast aortography. The results of the study indicate that radionuclide angiography may well have a useful role to play in determining the type of contrast st...

journal_title：Nuclear medicine communications

authors： Grime JS,Critchley M,Whitehouse GH,Zavras G

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:ECG-gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy combined with phase analysis allows for the assessment of left ventricular dyssynchrony. However, there are several software programs available thereby introducing variability in outcome and normal values. The aim ...

journal_title：Nuclear medicine communications

authors： Marques de Souza Filho E,Tinoco Mesquita C,Altenburg Gismondi R,de Amorim Fernandes F,Jan Verberne H

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The choice of metrics for defining active Takayasu arteritis (TAK) using fluorine-18-fluorodeoxyglucose (F-FDG)-PET remains controversial. OBJECTIVE:The aim of this study was to compare in the same patients the diagnostic performance for the detection of active TAK of different metrics applied for the qua...

journal_title：Nuclear medicine communications

authors： Emsen B,Benali K,Mahida B,Larivière D,Le Guludec D,Papo T,Sacre K,Hyafil F

更新日期：2018-08-01 00:00:00

abstract：:The extravascular concentration (Ce) of some renal agents, in relation to the simultaneous plasma concentration (Ci), was calculated as a function of time after intravenous injection. Four agents were studied: 51Cr-ethylenediamine tetraacetate (EDTA) (n = 11), 125I-hippuran (n = 11), 99Tcm-dimercaptosuccinic acid (DMS...

journal_title：Nuclear medicine communications

authors： Peters AM,Brown H,Cosgriff P

更新日期：1994-02-01 00:00:00

abstract：:The impact of recent advances in the chemical and genetic engineering manipulations of antibodies on radioimmunotargeting is reviewed both in relation to radioimmunoscintigraphy and radioimmunotherapy. The resulting trends are: (1) the linking of parts of the mouse/rat and human antibody molecule; (2) the creation of ...

journal_title：Nuclear medicine communications

authors： Hazra DK,Britton KE,Lahiri VL,Gupta AK,Khanna P,Saran S

更新日期：1995-02-01 00:00:00