Immunotechnological trends in radioimmunotargeting: from 'magic bullet' to 'smart bomb'.

abstract：OBJECTIVE:To investigate the relationship between the prognosis and glucose transporter-1 (Glut-1) expression or fluorine-18 fluorodeoxyglucose uptake using partial volume correction and dual-point imaging in surgically resected nonsmall cell lung cancer (NSCLC) patients. METHODS:Our patient population consisted of 10...

journal_title：Nuclear medicine communications

authors： Kaida H,Azuma K,Kawahara A,Takamori S,Akiba J,Fujimoto K,Ishii K,Ishibashi M

更新日期：2020-01-01 00:00:00

abstract：:An increased uptake of bone-seeking radiopharmaceuticals into malignant bone lesions could further improve the diagnostic accuracy of routine bone scanning. The tracers used in clinical routine for bone scanning are methylene-diphosphonate (MDP), dicarboxypropane-diphosphonate (DPD) and ethylenediaminetetramethylene-p...

journal_title：Nuclear medicine communications

authors： Fueger BJ,Mitterhauser M,Wadsak W,Ofluoglu S,Traub T,Karanikas G,Dudczak R,Pirich C

更新日期：2004-04-01 00:00:00

abstract：:A technique is described for the quantification of the three-dimensional distribution of 131I radiopharmaceuticals using single photon emission computed tomography (SPECT). A theoretical discussion of the problems of scatter and septal penetration in 131I SPECT is presented. The correction of these effects using the g...

journal_title：Nuclear medicine communications

authors： Fleming JS,Alaamer AA,Perring S

更新日期：1993-06-01 00:00:00

abstract：:The aim of the study was to evaluate pulmonary nodules (PNs) by incorporating time sensitivity (S) factor in the retention index (RI) and compare with the traditional fixed interval method. After obtaining approval from the Human Investigations Committee, 97 PNs from 81 patients (age=70±11) referred for dual-time fluo...

journal_title：Nuclear medicine communications

authors： Wong CY,Al-faham Z,Jolepalem P,Wong WW,Thie J

更新日期：2014-12-01 00:00:00

abstract：AIM:The aim of this study was to assess ablation outcome after a second ablation dose and compare the ablation rate after low and high reablation doses of iodine-131 ((131)I) after failure of the first ablation with 3700 MBq. PATIENTS AND METHODS:The study included 81 patients with papillary thyroid cancer; they faile...

journal_title：Nuclear medicine communications

authors： M El-Refaei S,W Yassin S,Salman K,Al Munshy T,Al-Ezzi M,M Al-Sayed Y,Abd Elkareem Husseni M

更新日期：2015-02-01 00:00:00

abstract：:The time course of thyroglobulin (Tg) was monitored in patients with differentiated thyroid carcinoma after ablative therapy (thyroidectomy + 131I-treatment) with particular respect to endogeneous antibodies (Tg-ABs). In 232 patients (196 without Tg-ABs, 36 with Tg-ABs at the time of treatment) a sensitivity of 88% (a...

journal_title：Nuclear medicine communications

authors： Moser E,Braun S,Kirsch CM,Kleinhans E,Buell U

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:To prevent salivary dysfunction in thyroid cancer patients who have undergone radioiodine ablation, massaging the parotid gland (PG) is presumed to be helpful for the removal of radioiodine. The purpose of this study was to evaluate the effect of PG massage in the removal of radioiodine from the PG. METHODS...

journal_title：Nuclear medicine communications

authors： Hong CM,Son SH,Kim CY,Kim DH,Jeong SY,Lee SW,Lee J,Ahn BC

更新日期：2014-11-01 00:00:00

abstract：:To evaluate right ventricular overload in paediatric patients with congenital cardiac disease (n = 25), the uptakes of 201Tl and 99Tcm-sestamibi (99Tcm-MIBI) were compared. 99Tcm-MIBI showed a clearer myocardial border and better contrast between the myocardium and ventricular cavity. Although hepatic activity may inf...

journal_title：Nuclear medicine communications

authors： Nakajima K,Taki J,Taniguchi M,Tonami N,Hisida K

更新日期：1995-11-01 00:00:00

abstract：:Should one correct for extrathyroidal neck radioactivity ('neck background') when interpreting perchlorate discharge test results? A new background correction method was developed using a linear probe. 123I produces photon peaks at two energy levels: 159 keV (gamma-rays) and 28 keV (X-rays), with an attenuation of 15 ...

journal_title：Nuclear medicine communications

authors： Arntzenius AB,van der Heide D,Meinders AE

更新日期：1992-11-01 00:00:00

abstract：:The aim of this prospective study was to assess the efficacy of using whole-kidney, mean parenchymal and pelvic transit times to evaluate renal function following treatment with extracorporeal shock wave lithotripsy (ESWL). Fifteen patients were evaluated 24-48 h before and after ESWL therapy using 99Tcm-DTPA renal sc...

journal_title：Nuclear medicine communications

authors： Ilgin N,Iftehar SA,Vural G,Bozkirli I,Gokcora N

更新日期：1998-02-01 00:00:00

abstract：INTRODUCTION:Gated myocardial perfusion scintigraphy (g-MPS) provides functional information on the left ventricle (LV) apart from the perfusion status. Computer algorithm-based LV ejection fraction (EF) calculated from resting g-MPS has been found to be reliable in patients with normal perfusion. However, its role in ...

journal_title：Nuclear medicine communications

authors： Harisankar CN,Mittal BR,Kamaleshwaran KK,Parmar M,Bhattacharya A,Singh B,Mahajan R

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the capability of F-FDG PET/computed tomography (CT)-related metabolic parameters to predict lymph node metastasis (LNM) and occult lymph node metastasis (OLNM) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:Totally 84 patients undergoing curative...

journal_title：Nuclear medicine communications

authors： Xu M,Wang L,Ouyang M,Lin J,Wang L,Zheng X,Miao S,Tang K

更新日期：2019-09-01 00:00:00

abstract：:An examination of the biokinetics and biodistribution of i.p. administered 131I- or 111In-labelled 791T/36 antibody (1 mg) has been carried out in five patients with stage III/IV ovarian cancer. Blood kinetics and urinary excretion of the radiolabels were assayed. Scintigraphy was performed immediately following admin...

journal_title：Nuclear medicine communications

authors： Perkins AC,Pimm MV,Gie C,Marksman RA,Symonds EM,Baldwin RW

更新日期：1989-08-01 00:00:00

abstract：PURPOSE:Extramammary Paget's disease (EMPD) is rare, and limited data have been reported on the utilization of fluorine-18 fluorodeoxyglucose PET/computed tomography ((18)F-FDG PET/CT) in this disease. The aim of this study is to evaluate the role of (18)F-FDG PET/CT in the diagnosis and staging of EMPD. MATERIALS AND...

journal_title：Nuclear medicine communications

authors： Tian Y,Wu HB,Li DL,Li HS,Zhou WL,Wang QS

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:The regions of significant correlation between cerebral hypoperfusion and neuropsychological assessment scores were evaluated using (99m)Tc-HMPAO SPECT in patients with mild cognitive impairment (MCI) on the basis of its three subtypes, namely, single-domain amnestic MCI (aMCI-s), multiple-domain amnestic MCI (...

journal_title：Nuclear medicine communications

authors： Yoon HJ,Park KW,Jeong YJ,Kang DY

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:To test the potential of a new reconstruction algorithm with Monte Carlo-based scatter correction in half-time myocardial perfusion single-photon emission computed tomography (SPECT). MATERIALS AND METHODS:The mathematical four-dimensional NURBS-based Cardiac-Torso phantom and the SIMIND Monte Carlo simulation...

journal_title：Nuclear medicine communications

authors： Kangasmaa TS,Kuikka JT,Vanninen EJ,Mussalo HM,Laitinen TP,Sohlberg AO

更新日期：2011-11-01 00:00:00

abstract：:Chronic synovitis often occurs in people with haemophilia. Untreated chronic haemophilic synovitis affects the metabolism of chondrocytes, thus leading to haemophilic arthropathy. A recently introduced therapeutic protocol includes radiation synovectomy (RS), a safe and cost-effective therapeutic method, which has giv...

journal_title：Nuclear medicine communications

authors： Teyssler P,Kolostova K,Bobek V

更新日期：2013-04-01 00:00:00

abstract：:The physical considerations of using dual isotope brain SPECT imaging to monitor blood flow changes during cognitive activation studies were investigated. These factors included field uniformity, spatial resolution and crosstalk. Serial dual isotope single photon emission computed tomographic (SPECT) studies of a test...

journal_title：Nuclear medicine communications

authors： Madsen MT,O'Leary DS,Andreasen NC,Kirchner PT

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:The NHS National PET-CT Audit Programme was launched in 2008 as part of a national NHS programme to widen patient access to PET-computed tomography (CT) imaging in England. However, to implement clinical audit effectively, healthcare professionals need to be fully engaged with the process. The purpose of the pi...

journal_title：Nuclear medicine communications

authors： Ross P,Hubert J,Saunders M,Wong WL

更新日期：2014-10-01 00:00:00

abstract：:Recombinant human thyrotropin (rhTSH) has been evaluated in 38 patients with differentiated thyroid cancer. The patients had all been treated previously by operation and 31 had received radioiodine 131I. The patients continued to take thyroid hormone and changed to a low iodine diet for 14 days before and throughout t...

journal_title：Nuclear medicine communications

authors： Durski JM,Weigel RJ,McDougall IR

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the combined effects of serum lipids, BMI, and fatty liver on the liver uptake of fluorine-18 fluorodeoxyglucose ((18)F-FDG). METHODS:A total of 676 individuals were retrospectively studied. The mean standardized uptake value (SUV) was used to quantify liver (18)F-FDG...

journal_title：Nuclear medicine communications

authors： Liu G,Li Y,Hu P,Cheng D,Shi H

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:The purpose of this study was to show the viability and performance of a shape-based pattern recognition technique applied to I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography (FP-CIT SPECT) in patients with parkinsonism. METHODS:A fully autom...

journal_title：Nuclear medicine communications

authors： Staff RT,Ahearn TS,Wilson K,Counsell CE,Taylor K,Caslake R,Davidson JE,Gemmell HG,Murray AD

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Follow-up of 131I whole-body scanning after 131I ablation is associated with potential stunning. Previous studies have suggested that, for scanning, 123I is more sensitive than 131I in identifying thyroid tissue, but its specificity when positive is less certain. AIM:The use of 123I as an imaging agent in p...

journal_title：Nuclear medicine communications

authors： Ali N,Sebastian C,Foley RR,Murray I,Canizales AL,Jenkins PJ,Drake WM,Plowman PN,Besser GM,Chew SL,Grossman AB,Monson JP,Britton KE

更新日期：2006-02-01 00:00:00

abstract：:High-quality positron emission tomographic (PET) cameras are expensive and, therefore, not available in many centres. To allow access to clinical 18F-fluorodeoxyglucose (18F-FDG) PET, we began working with an ADAC Vertex camera equipped with a molecular coincidence detection (MCD) module in February 1997. Here we give...

journal_title：Nuclear medicine communications

authors： Erler H,Zaknun J,Donnemiller E,Bacher-Stier C,Oberladstätter M,Riccabona G,Moncayo R

更新日期：1999-11-01 00:00:00

abstract：:Marked changes in cardiac function have been noted in patients with hyperthyroidism or hypothyroidism due both to changes in sympathetic system function and to biochemical modifications of myocardial tissue. Metaiodobenzylguanidine (MIBG), an analogue of norepinephrine, can be used to evaluate myocardial sympathetic t...

journal_title：Nuclear medicine communications

authors： Maini CL,Tofani A,Sciuto R,Ferraironi A,Festa A,Rea S

更新日期：1999-08-01 00:00:00

abstract：:The investigation of left ventricular contractile reserve usually requires the determination of left ventricular volume, but its measurement with radionuclide angiography is difficult. The aim of this study was to determine left ventricular volume directly during exercise by the simultaneous measurement of peak exerci...

journal_title：Nuclear medicine communications

authors： Faraggi M,Cohen-Solal A,Czitrom D,Sarda L,Lebtahi R,Daou D,Petegnief Y,Gourgon R,Guludec DL

更新日期：1996-12-01 00:00:00

abstract：:The results of scintigraphy in 29 patients with Cushing's syndrome were evaluated. It was possible to separate bilateral hyperplasia from unilateral abnormality. In cases of unilateral abnormality correct localization of the tumour was accomplished and it was possible to visualize adrenocortical carcinoma. The many ad...

journal_title：Nuclear medicine communications

authors： Lindberg S,Ernest I,Fjälling M,Holmdahl C

更新日期：1985-01-01 00:00:00

abstract：:The aim of this study was to examine the value of an additional atropine injection in patients who do not achieve an adequate heart rate during dobutamine infusion for myocardial perfusion SPET (single photon emission tomography). Patients undergoing dobutamine myocardial SPET who failed to achieve > or = 85% of their...

journal_title：Nuclear medicine communications

authors： Caner B,Karanfil A,Uysal U,Tokgozoglu L,Aksoyek S,Ugur O,Ciftci I,Atalar E,Kes S,Bekdik C

更新日期：1997-06-01 00:00:00

abstract：:The biodistribution of two stereoisomeric 99Tcm complexes derived from diastereomeric dimercaptosuccinic acids (DMSA), 99Tcm-dl-DMSA and 99Tcm-meso-DMSA, was examined in sarcoma 180 tumour-bearing mice. The biodistribution pattern of meso-complex was not significantly different from 99Tc(V)m-DMSA, a new tumour imaging...

journal_title：Nuclear medicine communications

authors： Awh OD,Kim JR,Shim SC

更新日期：1989-06-01 00:00:00

abstract：:Radioimmunoscintigraphy (RIS) and radioimmunoguided surgery (RIGS) were assessed for their usefulness in patients with colorectal carcinoma. Twenty-nine patients (18 primary tumours, 10 with a suspicion of recurrence and one colonic diverticulitis) were studied. Radioimmunoscintigraphy was performed 48 and 72 h after ...

journal_title：Nuclear medicine communications

authors： Muxi A,Pons F,Vidal-Sicart S,Setoain FJ,Herranz R,Novell F,Fernandez RM,Trias M,Setoain J

更新日期：1999-02-01 00:00:00