Half-time myocardial perfusion SPECT imaging with attenuation and Monte Carlo-based scatter correction.

Abstract:

PURPOSE:To test the potential of a new reconstruction algorithm with Monte Carlo-based scatter correction in half-time myocardial perfusion single-photon emission computed tomography (SPECT). MATERIALS AND METHODS:The mathematical four-dimensional NURBS-based Cardiac-Torso phantom and the SIMIND Monte Carlo simulation package were used to simulate full-time and half-time SPECT projection data. The data were reconstructed using the standard ordered subset expectation maximization-based algorithm and the new Monte Carlo-based algorithm. Defect contrast, myocardium versus ventricle contrast and resolution were calculated. In addition to the simulation studies, full-time and half-time SPECT projection data of 30 patients were reconstructed with the standard and the new method. The patient data were qualitatively evaluated by four nuclear medicine experts on a scale from 1 (poor quality) to 5 (high quality). RESULTS:The new reconstruction method with half-time data produced higher contrast and better resolution in the simulations and also achieved higher qualitative scores in the patient study than the standard reconstruction with full-time data. CONCLUSION:Half-time myocardial perfusion imaging using the new reconstruction algorithm with Monte Carlo-based scatter correction produced images with superior quality when compared with full-time imaging with standard reconstruction.

journal_name

Nucl Med Commun

authors

Kangasmaa TS,Kuikka JT,Vanninen EJ,Mussalo HM,Laitinen TP,Sohlberg AO

doi

10.1097/MNM.0b013e328349c765

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1040-5

issue

11

eissn

0143-3636

issn

1473-5628

pii

00006231-201111000-00010

journal_volume

32

pub_type

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