Radionuclide limb blood flow in peripheral vascular disease: a review of 1100 measurements.

Abstract:

:Radionuclide limb blood flow measurements using 99Tcm-labelled human serum albumin and a gamma camera have been performed on normal volunteers and on patients with suspected or confirmed peripheral arterial disease. The normal range of flow was found to be 10.0-22.3 ml per 100 ml tissue per min. Flow in the symptomatic legs of patients with arterial disease varied from 9.0 ml per 100 ml tissue per min in mild claudication to less than 1.0 ml per 100 ml tissue per min in rest pain. The technique has been used as an initial screening procedure, to resolve diagnostic problems, to measure objectively the treatment response and to assess patients with critical ischaemia. The results of 1100 measurements are reported and the clinical utility in routine vascular surgical practice is discussed.

journal_name

Nucl Med Commun

authors

Parkin A,Robinson PJ,Martinez D,Wilkinson D,Kester RC

doi

10.1097/00006231-199110000-00003

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

835-51

issue

10

eissn

0143-3636

issn

1473-5628

journal_volume

12

pub_type

杂志文章
  • InfuShield: a shielded enclosure for administering therapeutic radioisotope treatments using standard syringe pumps.

    abstract::The administration of radionuclide therapies presents significant radiation protection challenges. The aim of this work was to develop a delivery system for intravenous radioisotope therapies to substantially moderate radiation exposures to staff and operators. A novel device (InfuShield) was designed and tested befor...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000634

    authors: Rushforth DP,Pratt BE,Chittenden SJ,Murray IS,Causer L,Grey MJ,Gear JI,Du Y,Flux GD

    更新日期:2017-03-01 00:00:00

  • Scintigraphic imaging of breast cancer: a review.

    abstract::Scintimammography is a recently verified technique that will expand the use of nuclear medicine to a new group of patients in whom scintigraphic imaging has not been widely used. If performed correctly, and in certain groups of patients, it delivers a sensitivity as high as X-ray mammography or magnetic resonance imag...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,评审

    doi:10.1097/00006231-199708000-00003

    authors: Buscombe JR,Cwikla JB,Thakrar DS,Hilson AJ

    更新日期:1997-08-01 00:00:00

  • Clinical significance of extraskeletal computed tomography findings on 18F-NaF PET/CT performed for osseous metastatic disease evaluation.

    abstract:PURPOSE:Extraskeletal findings detected on whole-body low-dose unenhanced computed tomography (CT) as a part of F-NaF PET/CT scans can be numerous and present challenges for further management. Here, we investigate the frequency and clinical significance of extraskeletal findings among 130 consecutive patients undergoi...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000531

    authors: Guo HH,Moradi F,Iagaru A

    更新日期:2016-09-01 00:00:00

  • Quality of care: identification and quantification of the process of care among children undergoing nuclear medicine studies.

    abstract::The aim of this study was to define indices which could be used to assess the quality of care of children undergoing an examination requiring intravenous (i.v.) access in an integrated department of radiology and to see if these indices could be quantified. A prospective study of all patients requiring an i.v. injecti...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Sherazi Z,Gordon I

    更新日期:1996-05-01 00:00:00

  • Quantitation of skeletal muscle necrosis using 99Tcm-pyrophosphate with SPECT in a canine model.

    abstract::Patients with acute arterial occlusion may suffer from significant muscle necrosis. It is important to determine the amount of regional muscle necrosis for prognostic purposes and evaluation of therapy. We have used technetium-99m-pyrophosphate (PPi) with single photon emission computed tomography (SPECT) to quantitat...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199002000-00009

    authors: Yip TC,Houle S,Hayes G,Forrest I,Nelson L,Walker PM

    更新日期:1990-02-01 00:00:00

  • Specifying dual-detector gamma cameras and associated computer systems.

    abstract::Increasingly, dual-detector gamma cameras are being purchased as replacements for single-headed cameras. The improvement in sensitivity offered by a dual-detector device can be used in several ways: to shorten acquisition times, to improve signal-to-noise ratios, or to reduce administered doses. This paper focuses on ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,评审

    doi:10.1097/00006231-199507000-00003

    authors: Tindale WB

    更新日期:1995-07-01 00:00:00

  • Influence of statistical noise on the determination of the single kidney 99Tcm-DTPA clearance.

    abstract::Single kidney clearance can be obtained using the 99Tcm-DTPA complex and the scintillation camera. In order to evaluate the influence of statistical noise on the determination of the clearance, several non-noisy curves were constructed, simulating renal, background and precordial curves. Poisson noise was added to the...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198508000-00008

    authors: Piepsz A,Dobbeleir A,Ham HR

    更新日期:1985-08-01 00:00:00

  • Comparison of methods for quantification of transient ischaemic dilation in myocardial perfusion SPET.

    abstract::The purpose of this study was to compare six methods of measuring the left ventricular (LV) transient ischaemic dilation (TID) ratio during stress-rest myocardial perfusion single-photon emission tomography (SPET). The TID ratio was defined as the mean LV short-axis area at stress divided by the mean LV area of simila...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200010000-00013

    authors: Peace RA,McKiddie FI,Staff RT,Gemmell HG

    更新日期:2000-10-01 00:00:00

  • Stress-only myocardial perfusion scintigraphy: a prospective study on the accuracy and observer agreement with quantitative coronary angiography as the gold standard.

    abstract:OBJECTIVE:Patients with normal stress perfusion have an excellent prognosis. Prospective studies on the diagnostic accuracy of stress-only scans with contemporary, independent examinations as gold standards are lacking. PATIENTS AND METHODS:A total of 109 patients with typical angina and no previous coronary artery di...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0000000000000739

    authors: Ejlersen JA,May O,Mortensen J,Nielsen GL,Lauridsen JF,Allan J

    更新日期:2017-11-01 00:00:00

  • Enhanced uptake of 99Tcm-MDP in skeletal metastases from prostate cancer following initiation of hormone treatment: potential for increasing delivery of therapeutic agents.

    abstract::Following androgen ablation therapy, skeletal metastases from prostate cancer appear in some instances to show an increase in 99Tcm-methylene diphosphonate (99Tcm-MDP) uptake. Such a phenomenon could represent a mechanism to increase delivery of bone-seeking therapeutic agents to skeletal metastatic sites. The aim of ...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-199910000-00002

    authors: Bushnell DL,Madsen M,Kahn D,Nathan M,Williams RD

    更新日期:1999-10-01 00:00:00

  • 99Tcm-HMPAO leucocyte labelling in orofacial granulomatosis and gastrointestinal Crohn's disease in childhood and early adulthood.

    abstract::Orofacial granulomatosis is a granulomatous inflammatory disorder, affecting the soft tissues of the face and mouth. The predominant feature is disfiguring lip swelling. Patients with this condition may be exhibiting a Type IV hypersensitivity reaction to dietary or environmental allergens, or these may be the orofaci...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200002000-00006

    authors: Gibson J,Neilly JB,Wray AP,Evans TJ,MacKenzie JR,McKillop JH

    更新日期:2000-02-01 00:00:00

  • The effectiveness of low-dose versus high-dose 99mTc MIBI protocols for radioguided surgery in patients with primary hyperparathyroidism.

    abstract:OBJECTIVE:The aim of this study was to compare the efficacy of low-dose and high-dose (99m)Tc methoxy isobutyl isonitrile (MIBI) protocols in intraoperative localization of parathyroid adenomas by means of a gamma probe in patients with primary hyperparathyroidism (PHPT). PATIENTS AND METHODS:The study included 62 pat...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000056

    authors: Gencoglu EA,Aras M,Moray G,Aktas A

    更新日期:2014-04-01 00:00:00

  • Diagnostic value of ventilation/perfusion single-photon emission computed tomography/computed tomography for bronchiolitis obliterans syndrome in patients after lung transplantation.

    abstract:OBJECTIVE:To evaluate the diagnostic value of function volume/morphological volume ratio calculated from ventilation/perfusion single-photon emission computed tomography/computed tomography in distinguishing the lungs with bronchiolitis obliterans syndrome (BOS) from the lungs without this syndrome after lung transplan...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001021

    authors: Nakashima M,Shinya T,Oto T,Okawa T,Takeda Y

    更新日期:2019-07-01 00:00:00

  • Effect of different segmentation algorithms on metabolic tumor volume measured on 18F-FDG PET/CT of cervical primary squamous cell carcinoma.

    abstract:BACKGROUND AND PURPOSE:It is known that fluorine-18 fluorodeoxyglucose PET/computed tomography (CT) segmentation algorithms have an impact on the metabolic tumor volume (MTV). This leads to some uncertainties in PET/CT guidance of tumor radiotherapy. The aim of this study was to investigate the effect of segmentation a...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000641

    authors: Xu W,Yu S,Ma Y,Liu C,Xin J

    更新日期:2017-03-01 00:00:00

  • Cerebral uptake and retention of 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HM-PAO).

    abstract::A new radiopharmaceutical, 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HM-PAO) is described. This agent displays considerable promise for imaging cerebral blood flow. In studies in rats and one human volunteer, 99Tcm-HM-PAO demonstrates good brain uptake, prolonged retention of activity in the brain, and slow regional...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198508000-00003

    authors: Holmes RA,Chaplin SB,Royston KG,Hoffman TJ,Volkert WA,Nowotnik DP,Canning LR,Cumming SA,Harrison RC,Higley B

    更新日期:1985-08-01 00:00:00

  • Diagnostic accuracy of 18F-FDG PET/CT in characterizing ovarian lesions and staging ovarian cancer: correlation with transvaginal ultrasonography, computed tomography, and histology.

    abstract:AIMS:To (a) assess the accuracy of 18F-FDG PET/CT in distinguishing malignant from benign pelvic lesions, compared to transvaginal ultrasonography (TVUS) and (b) to establish the role of whole-body 18F-FDG PET/CT, compared to contrast enhanced computed tomography (CT), in staging patients with ovarian cancer. PATIENTS...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0b013e3281afa256

    authors: Castellucci P,Perrone AM,Picchio M,Ghi T,Farsad M,Nanni C,Messa C,Meriggiola MC,Pelusi G,Al-Nahhas A,Rubello D,Fazio F,Fanti S

    更新日期:2007-08-01 00:00:00

  • Radiolabeled sucralfate: a review of clinical efficacy.

    abstract::Radiolabeled sucralfate has been utilized by several investigators to evaluate peptic ulcer, active inflammatory bowel disease, esophageal ulcer, and gastric cancer. A review of the available literature indicates that radiolabeled sucralfate has been used to evaluate peptic ulcer and active inflammatory bowel diseases...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,评审

    doi:

    authors: Vasquez TE,Pretorius HT,Greenspan G

    更新日期:1987-05-01 00:00:00

  • 99mTcN complexes of tert-butyl dithiocarbamate and methoxyisobutyl dithiocarbamate as myocardial and brain imaging agents.

    abstract:OBJECTIVE:Two ligands viz. tert-butyl dithiocarbamate (TBDTC) and methoxyisobutyl dithiocarbamate (MIBDTC), which are analogous to the tert-butyl isonitrile (TBI) and sestamibi (MIBI) ligands, were synthesized and labelled with the [99mTcN] core to evaluate their potential as myocardial agents. As these complexes have ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/01.mnm.0000183793.51474.2f

    authors: Mathur A,Mallia MB,Subramanian S,Banerjee S,Kothari K,Dhotare B,Sarma HD,Venkatesh M

    更新日期:2005-11-01 00:00:00

  • 99Tcm-HMPAO brain SPET in patients with pseudotumour cerebri.

    abstract::The aim of this study was to look for regional cerebral blood flow (rCBF) abnormalities in patients with a recent diagnosis of pseudotumour cerebri (PTC) and to compare 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) cerebral single photon emission tomographic (SPET) findings with those of X-ray computed tomograph...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199608000-00009

    authors: Bakar M,Tamgac F,Alper E,Zarifoglu M,Bora I,Turan F,Ogul E

    更新日期:1996-08-01 00:00:00

  • A comparison between 11C-methionine PET/CT and MIBI SPECT/CT for localization of parathyroid adenomas/hyperplasia.

    abstract:OBJECTIVE:The purpose of this study was to compare the sensitivity of single-photon emission computed tomography/computed tomography (SPECT/CT) using 99mTc-sestamibi (MIBI) with that of PET/CT using 11C-methionine (MET) for localization of parathyroid adenomas/hyperplasia in primary hyperparathyroidism. MATERIALS AND ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000216

    authors: Hayakawa N,Nakamoto Y,Kurihara K,Yasoda A,Kanamoto N,Miura M,Inagaki N,Togashi K

    更新日期:2015-01-01 00:00:00

  • Clinical relevance of 18F-FDG-negative osteoblastic metastatic bone lesions noted on PET/CT in breast cancer patients.

    abstract:PURPOSE:Our study aims to assess the clinical relevance of fluorine-18 fluorodeoxyglucose (F-FDG) negative osteoblastic metastatic bone lesions noted on PET/computed tomography (CT) in breast cancer patients. PATIENTS AND METHODS:The medical records of breast cancer patients were reviewed retrospectively from January ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000481

    authors: Al-Muqbel KM,Yaghan RJ,Al-Omari MH,Rousan LA,Dagher NM,Al Bashir S

    更新日期:2016-06-01 00:00:00

  • The impact of radiopharmaceutical particle size on the visualization and identification of sentinel nodes in breast cancer.

    abstract:OBJECTIVES:The aim of this study was to compare the success rate in lymphatic mapping and sentinel node biopsy in breast cancer using two radiopharmaceuticals. METHODS:The study included 119 breast cancer patients who underwent lymphoscintigraphy after a single intratumoral injection of 99mTc-labelled human albumin co...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200403000-00004

    authors: Leidenius MH,Leppänen EA,Krogerus LA,Smitten KA

    更新日期:2004-03-01 00:00:00

  • Does P-glycoprotein have a role in the lung clearances of inhaled 99mTc-sestamibi and 99mTc-tetrofosmin?

    abstract:OBJECTIVE:The clearance rate of inhaled 99mTc-sestamibi from the lungs of healthy nonsmoking individuals is much slower than would be expected from its physical properties. The clearance rate is even slower in healthy cigarette smokers. As 99mTc-sestamibi is a substrate for P-glycoprotein (P-gp), pulmonary P-gp may be ...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0b013e32832b9a2d

    authors: Cheow HK,Ruparelia P,Shankar S,Szczepura KR,Ballinger JR,Hartman NG,Chilvers ER,Peters AM

    更新日期:2009-08-01 00:00:00

  • Long-term follow-up using 18F-FDG PET/CT for postoperative olfactory neuroblastoma.

    abstract:PURPOSE:The present study evaluated the usefulness of postoperative fluorine-18 fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) in the management of olfactory neuroblastoma (ONB). MATERIALS AND METHODS:Ten patients (eight men and two women; mean age, 48.5 years) with histologically confirmed ONB who underwent ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000135

    authors: Fujioka T,Toriihara A,Kubota K,Machida Y,Nakamura S,Kishimoto S,Ohashi I,Shibuya H

    更新日期:2014-08-01 00:00:00

  • Depression and anxiety during isolation and radionuclide therapy.

    abstract::The combination of a diagnosis of malignancy and hospitalization, isolation and radioactivity of a radionuclide therapy may have an important effect on the psychological equilibrium of patients and may hamper compliance and acceptability. We performed a psychiatric evaluation in order to study psycho-pathological mani...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.mnm.0000084586.29433.83

    authors: Brans B,van den Eynde F,Audenaert K,Vervaet M,van Daele K,van Heeringen C,Dierckx RA

    更新日期:2003-08-01 00:00:00

  • Dual-time 18F-FDG PET/CT for the detection of liver metastases in breast cancer.

    abstract:OBJECTIVE:The aim was to investigate the diagnostic potential of dual-time-point F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) in patients with breast cancer with known or suspected liver metastases and to assess its clinical value on clinical management. PATIENTS AND METHODS:A t...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000918

    authors: Annovazzi A,Rea S,Vici P,Fabi A,Sciuto R

    更新日期:2018-12-01 00:00:00

  • Should the presence of other diseases exclude subjects as controls in studies of gallbladder response to cholecystokinin octapeptide (sincalide)? Scintigraphic results in patients with malignancies but no known gallbladder disease.

    abstract::Findings of hepatobiliary scintigraphy with intravenous cholecystokinin octapeptide (sincalide) were examined in 26 asymptomatic patients with various malignancies but no known pre-existing gallbladder disease, and normal hepatobiliary and gallbladder morphology on sonography. The maximum gallbladder ejection fraction...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199606000-00010

    authors: Jacobson AF,Teefey SA

    更新日期:1996-06-01 00:00:00

  • 99Tcm-methoxy-isobutyl-isonitrile SPECT to evaluate a perfusion index from regional myocardial uptake after exercise and at rest. Results of a four hour protocol in patients with coronary heart disease and in controls.

    abstract::In 70 patients with angiographically confirmed coronary heart disease and in 10 controls, a 4 h exercise (E) (injection of 150 MBq 99Tcm-MIBI) rest (R) (800 MBq) protocol was employed. Of these, 10 patients with 21 myocardial defects after E received a third injection 24 h after. SPECT was used to image myocardial dis...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199002000-00002

    authors: Buell U,Dupont F,Uebis R,Kaiser HJ,Kleinhans E,Reske SN,Hanrath P

    更新日期:1990-02-01 00:00:00

  • In vivo kinetics of 123I-labelled insulin: studies in normal subjects and patients with diabetes mellitus.

    abstract::Radioactive tracer techniques using 131I- and 125I-insulin have been applied to study insulin metabolism. A simple method to label human insulin with 123I to a high specific activity is described. We have used this radiotracer to study insulin kinetics in vivo in normal subjects and in two groups of diabetic patients....

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198710000-00003

    authors: Sinclair AJ,Signore A,Bomanji J,Britton KE,Pozzilli P,Gale EA

    更新日期:1987-10-01 00:00:00

  • 99Tcm-diastereomeric dimercaptosuccinic acid complexes: comparison of their biodistribution.

    abstract::The biodistribution of two stereoisomeric 99Tcm complexes derived from diastereomeric dimercaptosuccinic acids (DMSA), 99Tcm-dl-DMSA and 99Tcm-meso-DMSA, was examined in sarcoma 180 tumour-bearing mice. The biodistribution pattern of meso-complex was not significantly different from 99Tc(V)m-DMSA, a new tumour imaging...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198906000-00011

    authors: Awh OD,Kim JR,Shim SC

    更新日期:1989-06-01 00:00:00