Challenges for nuclear medicine in the 1990s.

abstract：OBJECTIVES:The aim of the study was to investigate the combined effects of serum lipids, BMI, and fatty liver on the liver uptake of fluorine-18 fluorodeoxyglucose ((18)F-FDG). METHODS:A total of 676 individuals were retrospectively studied. The mean standardized uptake value (SUV) was used to quantify liver (18)F-FDG...

journal_title：Nuclear medicine communications

authors： Liu G,Li Y,Hu P,Cheng D,Shi H

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:The metabotropic glutamate receptor subtype 5 (mGluR5) is distributed throughout the central nervous system (CNS), and has been suggested to be a potential target for several CNS disorders suchas Parkinson's disease, pain, anxiety, depression, schizophrenia, and addiction. We report here on the rhesus monk...

journal_title：Nuclear medicine communications

authors： Bélanger MJ,Krause SM,Ryan C,Sanabria-Bohorquez S,Li W,Hamill TG,Burns HD

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:We investigated the role of Ga-68 DOTATATE PET/CT in comparison to F-18 FDG PET/CT in patients with low and intermediate versus high-grade neuroendocrine tumors (NETs). METHODS:We identified 81 patients who underwent Ga-68 DOTATATE PET/CT at our institution between May 2017 and December 2018 and met inclusio...

journal_title：Nuclear medicine communications

authors： You H,Kandathil A,Beg M,De Blanche L,Kazmi S,Subramaniam RM

更新日期：2020-10-01 00:00:00

abstract：:In the presence of abnormal fluid collection (e.g. ascites), the measurement of glomerular filtration rate (GFR) based on a small number (1-4) of plasma samples fails. This study investigated how a few samples will allow adequate characterization of plasma clearance to give a robust and accurate GFR measurement. A tot...

journal_title：Nuclear medicine communications

authors： Murray AW,Gannon MA,Barnfield MC,Waller ML

更新日期：2012-09-01 00:00:00

abstract：:Single photon emission computed tomography (SPECT) imaging of dopamine transporters by using the cocaine derivative [123I]-(1R)-2-beta-carbomethoxy-3-beta-(4-iodophenyl)-tropane ([123I]-beta-CIT) has been shown to be useful in patients with Parkinsonism. The aim of this study was to compare beta-CIT imaging with singl...

journal_title：Nuclear medicine communications

authors： Eising EG,Müller TH,Freudenberg L,Müller SP,Dutschka K,Sonnenschein W,Przuntek H,Bockisch A

更新日期：2001-02-01 00:00:00

abstract：:At present, it is difficult to distinguish between bacterial infections and sterile inflammatory processes using radiopharmaceuticals. This is so for a variety of reasons, including binding to bacteria with low affinity (e.g. infection) and binding to a specific micro-organism (e.g. radiolabelled monoclonal antibodies...

journal_title：Nuclear medicine communications

authors： Nibbering PH,Welling MM,van den Broek PJ,van Wyngaarden KE,Pauwels EK,Calame W

更新日期：1998-12-01 00:00:00

abstract：:Alzheimer's disease is associated with a loss in presynaptic cholinergic function. It has been suggested that cholinergic inhibitors such as donepezil hydrochloride (Donepezil) could restore this function and improve some of the symptoms of Alzheimer's disease. Previous work has shown that Donepezil improves cognitive...

journal_title：Nuclear medicine communications

authors： Staff RT,Gemmell HG,Shanks MF,Murray AD,Venneri A

更新日期：2000-01-01 00:00:00

abstract：:We investigated a simple and reliable method for the preparation of 99Tcm-dimercaptosuccinic acid (99Tcm(V)-DMSA) without the addition of oxygen. The effect of pH, amount of reducing agent, and oxygen addition in the synthesis of 99Tcm(V)-DMSA were evaluated. At pH 9, we obtained a radiochemical yield of 95% +/- 1.2% ...

journal_title：Nuclear medicine communications

authors： Oh SJ,Ha HJ,Moon DH,Ryu JS,Lee HK

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:Myocardial perfusion SPECT is frequently affected by artefacts related to abdominal activity. Metoclopramide has been suggested to relieve this, but two previous studies have shown conflicting results. METHODS:Ninety-five patients received 10 mg metoclopramide orally after injection of 99mTc-tetrofosmin for...

journal_title：Nuclear medicine communications

authors： Grüning T,Brogsitter C,Khonsari M,Jones IW,Nevin SM,Burchert W

更新日期：2006-12-01 00:00:00

abstract：:The advent of PET instrumentation signaled the beginning of a new perspective in nuclear medicine diagnostic imaging. PET systems rely on several corrections that must be applied in order to establish accurate and reliable quantification. The inherent properties of PET detector architecture and the crystals themselves...

journal_title：Nuclear medicine communications

authors： Theodorakis L,Loudos G,Prassopoulos V,Kappas C,Tsougos I,Georgoulias P

更新日期：2013-11-01 00:00:00

abstract：AIM:99mTc-HL91 is a new hypoxia agent and can identify acutely ischaemic viable myocardium in a canine model using a standard gamma camera. The purpose of the study was to determine whether this tracer could be used to detect regional ischaemia in chronic ischaemic myocardium in a swine model. METHOD:Using a porcine m...

journal_title：Nuclear medicine communications

authors： Wu YW,Lee CM,Huang YH,Chou NK,Yen RF,Tzen KY,Huang PJ

更新日期：2005-12-01 00:00:00

abstract：:Salivary gland scintigraphy (SGS) is used to depict salivary gland dysfunction after radiotherapy (RT). The aim of this study was to investigate the utility of SGS combined with single photon emission computed tomography (SPECT). Twenty-one patients with a carcinoma of head and neck underwent SGS before and 1 month af...

journal_title：Nuclear medicine communications

authors： van Acker F,Flamen P,Lambin P,Maes A,Kutcher GJ,Weltens C,Hermans R,Baetens J,Dupont P,Rijnders A,Maes A,van den Bogaert W,Mortelmans L

更新日期：2001-02-01 00:00:00

abstract：:In busy nuclear medicine departments, the F+0 protocol for diuretic renography is routinely used to shorten the acquisition time. The aim of this study was to evaluate the influence of the F+0 protocol on the split renal function (SRF) during a dynamic renal scan using technetium-99m diethylene triamine pentaacetic ac...

journal_title：Nuclear medicine communications

authors： Kandeel AA,Elhossainy SA,Elsayed ND

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Brain metastases are common in lung cancer. Whole-body 2-deoxy-2-[fluorine-18]fluoro-D-glucose ([F]FDG) PET/computed tomography (CT) is used for general staging, but MRI is the best modality for characterizing brain abnormalities. We aimed to determine whether PET/CT is suitable for selecting patients for MRI...

journal_title：Nuclear medicine communications

authors： Hjorthaug K,Højbjerg JA,Knap MM,Tietze A,Haraldsen A,Zacho HD,Kramer SM,Borghammer P

更新日期：2015-11-01 00:00:00

abstract：:Technetium-99m-sestamibi (99mTc-MIBI) imaging is a well-established modality in oncologic investigations. The current study aimed to investigate whether any relationship could be found between 99mTc-MIBI uptake and local perfusion in malignant bone and soft-tissue tumours. It also aimed to compare 99mTc-MIBI images wi...

journal_title：Nuclear medicine communications

authors： Ozcan Z,Burak Z,Erinç R,Dirlik A,Başdemir G,Sabah D,Ozkiliç H

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:This radiotherapy planning study evaluated tumour delineation using both optimally respiratory gated and nongated fluorine-18 fluorodeoxyglucose-PET (F-FDG-PET). METHODS:For 22 non-small-cell lung tumours, both scans were used to create the nongated and gated (g) gross tumour volumes (GTVg) together with the...

journal_title：Nuclear medicine communications

authors： Wijsman R,Grootjans W,Troost EG,van der Heijden EH,Visser EP,de Geus-Oei LF,Bussink J

更新日期：2016-01-01 00:00:00

abstract：:Renal artery stenosis is an important and potentially curable cause of hypertension. Captopril renography is now recognized to have a high sensitivity and specificity in its diagnosis. Ultimately, however, the result is of little benefit if it does not lead to a change in patient management. To assess how patient mana...

journal_title：Nuclear medicine communications

authors： Ramsay D,Belton I,Finlay D

更新日期：1997-07-01 00:00:00

abstract：:To evaluate the clinical utility of 123I-labelled 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (123I-BMIPP), myocardial scintigraphy using 123I-BMIPP was performed in 13 patients with hypertrophic cardiomyopathy (HCM), and the findings were compared with those of 201Tl. The uptake of each tracer was scored visual...

journal_title：Nuclear medicine communications

authors： Ohtsuki K,Sugihara H,Umamoto I,Nakamura T,Nakagawa T,Nakagawa M

更新日期：1994-06-01 00:00:00

abstract：:In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

journal_title：Nuclear medicine communications

authors： Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

更新日期：1989-11-01 00:00:00

abstract：:Simultaneous assessment of regional adrenergic activity and perfusion with 123I-meta-iodobenzylguanidine (123I-MIBG) and 201Tl in various organs was performed in 13 patients with congestive heart failure (CHF) and 13 subjects without heart failure. In order to reduce the crosstalk of 201Tl to the 123I energy window to...

journal_title：Nuclear medicine communications

authors： Seto H,Shimizu M,Nozawa T,Yoshida N,Inagaki S,Kageyama M,Kakishita M

更新日期：1996-03-01 00:00:00

abstract：:N-isopropyl-p-I-123-iodoamphetamine (123I-IMP) is extracted by the brain in proportion to regional blood flow. It is particularly useful in the clinical assessment of various pathological conditions related to altered cerebral flow. Moreover, it has been reported that 123I-IMP is avidly incorporated into melanin and m...

journal_title：Nuclear medicine communications

authors： Watanabe N,Seto H,Yokoyama K,Matsuda H,Shimizu M,Tonami N,Hisada K,Kakishita M

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to identify deficiencies in product labelling instructions for reconstitution and in the quality control directions detailed in the technical leaflets (TLs) or summary product characteristic (SPC) sheets of commonly used technetium labelling cold kits. MATERIALS AND METHODS:The recon...

journal_title：Nuclear medicine communications

authors： Buroni FE,Lodola L,Persico MG,Aprile C

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...

journal_title：Nuclear medicine communications

authors： Cohen JB,Kalinyak JE,McDougall IR

更新日期：2004-02-01 00:00:00

abstract：:Following androgen ablation therapy, skeletal metastases from prostate cancer appear in some instances to show an increase in 99Tcm-methylene diphosphonate (99Tcm-MDP) uptake. Such a phenomenon could represent a mechanism to increase delivery of bone-seeking therapeutic agents to skeletal metastatic sites. The aim of ...

journal_title：Nuclear medicine communications

authors： Bushnell DL,Madsen M,Kahn D,Nathan M,Williams RD

更新日期：1999-10-01 00:00:00

abstract：:Venous thromboembolism (VTE) can present as deep vein thrombosis (DVT) and/or acute pulmonary embolism (PE). In fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT, 18F-FDG activity along the deep veins of the lower extremities (LE) is often observed and, unless it is associated with focal intense activity, is not conside...

journal_title：Nuclear medicine communications

authors： Zhu HJ,Hess S,Rubello D,Goris ML,Alavi A

更新日期：2016-03-01 00:00:00

abstract：:To assess the precision of gated equilibrium radioventriculography in measuring changes in left ventricular stroke volume (LVSV), we studied five dogs each with a chronically implanted electromagnetic flowmeter on the ascending aorta. Per cent changes in left ventricular stroke counts (LVSC) were compared to those in ...

journal_title：Nuclear medicine communications

authors： Valette H,Bourguignon MH,Apoil E,Moyse D,Wise RA,Buchanan JW,Wagner HN Jr,Syrota A

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVES AND METHODS:The recommended method for the measurement of radiochemical purity (RCP) of ¹¹¹In-labelled pentetreotide is thin-layer chromatography with a silica gel as the stationary phase and a 0.1 N sodium citrate solution (pH 5) as the mobile phase. According to the supplier's instructions, the mobile phas...

journal_title：Nuclear medicine communications

authors： Salgado-Garcia C,Montoza-Aguado M,Luna-Alcaide AB,Segovia-Gonzalez MM,de Mora ES,Lopez-Martin J,Ramos-Font C,Jimenez-Heffernan A

更新日期：2011-12-01 00:00:00

abstract：:We studied two different methods for the evaluation of differential renal function in a group of 100 patients with various kidney disorders whose effective renal plasma flow (ERPF) had been calculated previously by single 125I-orthoiodohippurate (OIH) injection and multiple blood sampling. Patients were divided into t...

journal_title：Nuclear medicine communications

authors： Llamas-Elvira JM,Martinez-Paredes M,Jimenez-Heffernan A,Sopena R,Requena MJ,Gonzalez FM,Torres M,Mateo A

更新日期：1989-10-01 00:00:00

abstract：AIM:To perform a detailed analysis of the performance of mobile intraoperative imaging systems and gamma probes in a phantom set-up, and compare this with a conventional gamma camera. METHODS:Two separate experiments were performed. In the first, a modified Jaszczak phantom equipped with five (99m)Tc-filled hot sphere...

journal_title：Nuclear medicine communications

authors： Krohn T,Verburg FA,Brockmann H,Winz OH,Mottaghy FM,Behrendt FF

更新日期：2012-05-01 00:00:00

abstract：:In this cross-sectional study, the relative importance of anthropometric factors and that of biological parameters on bone mineralization were evaluated and their practical implications inferred on the choice of the parameter to be used for the estimation of bone mineralization. A close relationship between anthropome...

journal_title：Nuclear medicine communications

authors： Rozenberg S,Ham H,Peretz A,Caufriez A,Bosson D,Robyn C

更新日期：1991-03-01 00:00:00