Comparison of 2D and 3D performance for FDG PET with different acquisition times in oncological patients.

Abstract:

OBJECTIVE:Collecting positron emission tomography data in three-dimensional (3D) mode may potentially allow reduction of the tracer dose and/or the acquisition time without compromising image quality thereby making the procedure more patient-friendly and cost effective. The objective of our study was to compare VUE Point iterative reconstruction algorithm in positron emission tomography data obtained in 3D and two-dimensional (2D) mode in routine clinical diagnostic setting in oncological patients. METHODS:Standard whole-body imaging (33 patients) was followed by rescanning of the target region in 2D and 3D mode. The ListMode data were histogrammed to 4, 3 and 2 min frames. Visual and semiquantitative analyses were performed. Effects of tumour volume and body mass index on tissue visualisation were evaluated. RESULTS:Visual image quality in 3D mode was superior to 2D. Maximum and mean standardised uptake values of tumours did not differ between 2D and 3D. Mean background standardised uptake values were significantly lower in 3D compared with 2D. 3D tumour to background ratios were higher than 2D in small lesions and obese patients (body mass index > or = 30) with all acquisition times. CONCLUSION:The new reconstruction method produces images of similar or better quality with 3D compared with 2D mode. The difference is pronounced in small lesions and in obese patients. According to our study, 3D is the preferred acquisition mode for routine whole-body evaluation of oncological patients.

journal_name

Nucl Med Commun

authors

Komar G,Teräs M,Seppänen M,Hirvonen J,Vahlberg T,Bergman J,Minn H

doi

10.1097/mnm.0b013e328315a22a

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

16-24

issue

1

eissn

0143-3636

issn

1473-5628

journal_volume

30

pub_type

杂志文章
  • Early effects of intra-arterial chemotherapy in patients with brain tumours studied with PET: preliminary results.

    abstract::In ten patients with malignant gliomas the regional cerebral metabolic rate for glucose (rCMRGlc) was studied with positron emission tomography (PET) using 2-18F-deoxyglucose (18FDG) before and within 1 to 7 days after intra-arterial chemotherapy with the nitrosourea derivative ACNU (iaACNU). Three patients were studi...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198911000-00002

    authors: Langen KJ,Roosen N,Kuwert T,Herzog H,Kiwit JC,Rota Kops E,Muzik O,Bock WJ,Feinendegen LE

    更新日期:1989-11-01 00:00:00

  • Contribution of 99mTc-anti-carcinoembryonic antigen antibody and 99mTc-sestamibi scintimammography in the evaluation of high risk palpable breast lesions.

    abstract::Mammography is the screening test of choice for breast cancer. Its low specificity leads to a large number of unnecessary biopsies. Scintimammography, with either Tc-sestamibi (MIBI) or Tc-anti-carcinoembryonic antigen (CEA) Fab', has been proposed as a non-invasive test to lower the high false positive rate of mammog...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200303000-00009

    authors: Sanidas EE,Koukouraki S,Velidaki A,Manios A,Stathopoulos E,De Bree E,Kafousi M,Kodogiannis E,Karkavitsas N,Tsiftsis DD

    更新日期:2003-03-01 00:00:00

  • Preparation of radioactive praseodymium oxide as a multifunctional agent in nuclear medicine: expanding the horizons of cancer therapy using nanosized neodymium oxide.

    abstract:OBJECTIVE:Many studies have attempted to assess the significance of the use of the β(-)particle emitter praseodymium-142 ((142)Pr) in cancer treatment. As praseodymium oxide (Pr(2)O(3)) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32835aa7bd

    authors: Bakht MK,Sadeghi M,Ahmadi SJ,Sadjadi SS,Tenreiro C

    更新日期:2013-01-01 00:00:00

  • A 5-year longitudinal evaluation in patients with mild cognitive impairment by 11C-PIB PET/CT: a visual analysis.

    abstract:OBJECTIVE:The aim of this study was to evaluate the cerebral amyloid distribution in patients with mild cognitive impairment (MCI), assessed by carbon-11-Pittsburgh compound B (C-PIB) PET/CT, after 5 years of follow-up. PATIENTS AND METHODS:Ten amnestic MCI (A-MCI) and four nonamnestic (NA-MCI) patients were studied b...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001004

    authors: Jiménez-Bonilla JF,Quirce R,De Arcocha-Torres M,Martínez-Rodríguez I,Martínez-Amador N,Sánchez-Salmón A,De la Fuente-Gómez F,Rodríguez E,Sánchez-Juan P,Banzo I

    更新日期:2019-05-01 00:00:00

  • The Bnai Zion Planar Method: a simplified technique for the quantitation of the absolute renal uptake of (99m)Tc-DMSA in children.

    abstract:AIM AND PURPOSE:Radionuclide imaging of the kidneys using dimercaptosuccinic acid chelate labeled with technetium-99m (Tc-DMSA) is a well-established method for evaluating the extent of kidney parenchymal involvement in the scenario of urinary tract infection and for the estimation of the functional renal mass. We have...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e3283396073

    authors: Gorenberg M,Radan L,Kosakov R,Amirav I

    更新日期:2010-07-01 00:00:00

  • Evaluation of renal function following treatment with extracorporeal shock wave lithotripsy (ESWL): the use of whole-kidney, parenchymal and pelvic transit times.

    abstract::The aim of this prospective study was to assess the efficacy of using whole-kidney, mean parenchymal and pelvic transit times to evaluate renal function following treatment with extracorporeal shock wave lithotripsy (ESWL). Fifteen patients were evaluated 24-48 h before and after ESWL therapy using 99Tcm-DTPA renal sc...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199802000-00010

    authors: Ilgin N,Iftehar SA,Vural G,Bozkirli I,Gokcora N

    更新日期:1998-02-01 00:00:00

  • 99mTc-sestamibi imaging and bone marrow karyotyping in the assessment of multiple myeloma and MGUS.

    abstract:AIM:The first pathogenetic step in multiple myeloma is the emergence of a limited number of clonal plasma cells, clinically known as monoclonal gammopathy of undetermined significance (MGUS). Patients with MGUS do not have symptoms or end-organ damage but they do have a 1% annual risk of progression to multiple myeloma...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e3282f5e5df

    authors: Giovanella L,Taborelli M,Ceriani L,Zucca E,Cavalli F,Delaloye AB

    更新日期:2008-06-01 00:00:00

  • Diagnostic utility of 99mTc-EDDA-tricine-HYNIC-Tyr3-octreotate SPECT for differentiation of active from inactive pulmonary tuberculosis.

    abstract:OBJECTIVE:The current study was performed to evaluate the impact of Tc-EDDA-tricine-HYNIC-Tyr-octreotate in the differentiation of active from inactive pulmonary tuberculosis lesions. PATIENTS AND METHODS:Ten consecutive patients (six male and four female, age range 24-83 years) with proven pulmonary tuberculosis (wit...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000206

    authors: Ahmadihosseini H,Abedi J,Ghodsi Rad MA,Zakavi SR,Knoll P,Mirzaei S,Sadeghi R

    更新日期:2014-12-01 00:00:00

  • The role of 99mTc-labelled glucosamine (99mTc-ECDG) in the evaluation of rheumatic joint disease: a screening experience.

    abstract:OBJECTIVES:We investigated the localization pattern of a novel imaging agent, (99m)Tc-labelled glucosamine (ECDG), in a variety of rheumatic conditions. MATERIALS AND METHODS:Sixteen patients were recruited into the study, with either active rheumatoid arthritis or osteoarthritis. (99m)Tc-ECDG was prepared in-house an...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000096

    authors: Angelides S,El-Mashaleh M,Anagnostou M,Howe G,Spencer D,Kumar V,Manolios N

    更新日期:2014-06-01 00:00:00

  • Fluorine-18 fluorodeoxyglucose avid thyroid incidentalomas on PET/CT scan in cancer patients: how sinister are they?

    abstract:OBJECTIVE:To evaluate the prevalence of malignancy in incidental thyroidal uptake on PET with fluorine-18 deoxyglucose integrated with computed tomography (F-FDG PET/CT) in Pakistani cancer patients and to assess the role of standardized uptake value (SUV) in deciding which lesions to investigate further. METHOD:We re...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000557

    authors: Hassan A,Riaz S,Zafar W

    更新日期:2016-10-01 00:00:00

  • A novel iterative method for lesion delineation and volumetric quantification with FDG PET.

    abstract:OBJECTIVES:The determination of lesion boundaries on FDG PET is difficult due to the point-spread blurring and unknown uptake of activity within a lesion. Standard threshold-based methods for volumetric quantification on PET usually neglect any size dependence and are biased by dependence on the signal-to-background ra...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0b013e328155d154

    authors: van Dalen JA,Hoffmann AL,Dicken V,Vogel WV,Wiering B,Ruers TJ,Karssemeijer N,Oyen WJ

    更新日期:2007-06-01 00:00:00

  • Removal of the internal mammary sentinel node in breast cancer.

    abstract:OBJECTIVE:The aim of the study was to determine the evolution of patients with internal mammary chain (IMC) drainage whether the IMC-sentinel lymph node (IMC-SLN) was biopsied or not, as well as to determine the clinical implications of the biopsy of the IMC-SLN (IMC-SLNB) in patients with breast cancer and IMC drainag...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e328330addf

    authors: Domènech-Vilardell A,Bajén MT,Benítez AM,Ricart Y,Mora J,Rodríguez-Bel L,García-Tejedor A,Climent J,López-Ojeda A,Urruticoechea A,Martín-Comín J

    更新日期:2009-12-01 00:00:00

  • Optimizing background correction when calculating differential renal function in the presence of hydroureteronephrosis using 99Tc(m)-DTPA.

    abstract::We performed a prospective study to establish the optimal background correction algorithm for the determination of differential renal function (DRF), using 99Tc(m)-diethylenetriamine pentaacetate (99Tc(m)-DTPA) in the presence of unilateral hydronephrosis, with 24 h 99Tc(m)-dimercaptosuccinic acid (99Tc(m)-DMSA) uptak...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199803000-00009

    authors: Van de Wiele C,De Sadeleer C,Koole M,D'Asseler Y,Everaert K,Dierckx RA

    更新日期:1998-03-01 00:00:00

  • UK audit of single photon emission computed tomography reconstruction software using software generated phantoms.

    abstract::The purpose of this study was to undertake an audit of the quantitative characteristics of single photon emission computed tomography software using projection data from an analytically generated software phantom and a measured line source. The phantom consisted of three structures. A uniformly filled cylinder, a seri...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200205000-00009

    authors: Jarritt PH,Whalley DR,Skrypniuk JV,Houston AS,Fleming JS,Cosgriff PS

    更新日期:2002-05-01 00:00:00

  • Comparison of fluorodeoxyglucose positron emission tomography and "conventional diagnostic procedures" for the detection of distant metastases in breast cancer patients.

    abstract::The presence of distant metastases is the main prognostic factor in patients with breast cancer and has a significant influence in the choice of therapy. Therefore, chest X-ray, bone scintigraphy and ultrasound of the abdomen are performed to detect distant metastases at diagnosis and follow-up. Fluorodeoxyglucose pos...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200209000-00009

    authors: Dose J,Bleckmann C,Bachmann S,Bohuslavizki KH,Berger J,Jenicke L,Habermann CR,Jãnicke F

    更新日期:2002-09-01 00:00:00

  • Visual and semiquantitative analysis of 82Rb uptake in malignant tumors on PET/CT: first systematic analysis.

    abstract:OBJECTIVE:The objective of this study was to analyze the uptake of rubidium in malignant tumors. PARTICIPANTS AND METHODS:Sixteen malignant lesions were included. Two radiologists compared each lesion to four references (subcutaneous fat, lung, mediastinal blood pool, and liver) at rest and stress and scored as 1-4. M...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001011

    authors: Khandani AH,Commander CW,Desai H,Oldan JD,Wong TZ,Benefield T,Ivanovic M

    更新日期:2019-05-01 00:00:00

  • Uptake of 123I-5-iodo-2-thiouracil, a possible radiopharmaceutical for noninvasive detection of ocular melanoma, in melanotic and amelanotic melanomas in hamsters.

    abstract::The uptake of 123I-5-iodo-2-thiouracil in melanotic and amelanotic melanoma implanted in Syrian golden hamsters was studied. A selective accumulation was found in the tumours. Uptake of 123ITU in melanotic melanomas was 4 to 5 times the uptake in amelanotic ones. For both tumours high ratios of tumours versus non-tumo...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198510000-00007

    authors: Franken NA,Van Langevelde A,Journée-De Korver JG,Bakker CN,Feitsma RI,Van Delft JL,Oosterhuis JA,Pauwels EK

    更新日期:1985-10-01 00:00:00

  • A 99Tcm-labelled leukotriene B4 receptor antagonist for scintigraphic detection of infection in rabbits.

    abstract::In a search for a rapid and accurate imaging agent for scintigraphic detection of infection and inflammation, an LTB4 receptor antagonist, 99Tcm-RP517, which contains the hydrazino nicotinamide moiety, has been developed recently. To study the in vivo behaviour of 99Tcm-RP517, rabbits with Escherichia coli infection w...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200011000-00010

    authors: Brouwers AH,Laverman P,Boerman OC,Oyen WJ,Barrett JA,Harris TD,Edwards DS,Corstens FH

    更新日期:2000-11-01 00:00:00

  • Detection of norepinephrine distribution in rats with adrenal medulla autotransplants using 125I-meta-iodobenzyl guanidine.

    abstract::The viability of autologous adrenal medullary transplants was evaluated using 125I-meta-iodobenzyl guanidine (MIBG), an adrenal medullary scanning agent. Bilateral cavities in the caudate nuclei were made stereotaxically in Wistar rats. One week later, the left adrenal medulla was resected by microsurgery, followed by...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199409000-00015

    authors: Shinoda M,Suzuki Y,Oi S,Tsugane R,Sato O

    更新日期:1994-09-01 00:00:00

  • Evaluation of bile duct complications after orthotopic liver transplantation by hepatobiliary scanning.

    abstract::A new radiopharmaceutical for hepatobiliary scanning, 99Tcm Iodida, which has significant advantages in patients with high bilirubinaemia, was used to assess biliary tract complications in 30 consecutive liver transplant patients. There was adequate hepatic extraction and excretion for diagnostic imaging even in patie...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199011000-00005

    authors: Lantsberg S,Lanchbury EE,Drolc ZA

    更新日期:1990-11-01 00:00:00

  • Interpretation, accuracy and management implications of FDG PET/CT in cutaneous malignant melanoma.

    abstract:PURPOSE:To investigate the accuracy of different interpretative approaches and to evaluate the management implications of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in cutaneous malignant melanoma. METHODS:We retrospectively identified 60 consecutive patients who underwent 76 PET/...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0b013e3280708ecf

    authors: Falk MS,Truitt AK,Coakley FV,Kashani-Sabet M,Hawkins RA,Franc B

    更新日期:2007-04-01 00:00:00

  • (99m)Tc-E-selectin binding peptide for imaging acute osteomyelitis in a novel rat model.

    abstract:INTRODUCTION:In the present study, (99m)Tc-radiolabelled E-selectin binding peptide ((99m)Tc-IMP-178) was investigated for its potential to image acute pyogenic osteomyelitis in a new animal model. Intraindividual comparisons were performed using an irrelevant peptide ((99m)Tc-IMP-100) to demonstrate specificity. METH...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200109000-00010

    authors: Gratz S,Béhé M,Boerman OC,Kunze E,Schulz H,Eiffert H,O'Reilly T,Behr TM,Angerstein C,Nebendahl K,Kauer F,Becker W

    更新日期:2001-09-01 00:00:00

  • 201Tl myocardial perfusion SPET: adenosine alone or combined with dynamic exercise.

    abstract::201Tl myocardial perfusion single photon emission tomography (SPET) with pharmacological coronary vasodilatation using adenosine is now often used in the investigation of a patient with ischaemic heart disease (IHD). In this study, we present data from two groups of patients. Group A (n = 40) experienced 201Tl SPET wi...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-199408000-00003

    authors: Mahmood S,Gupta NK,Gunning M,Bomanji JB,Jarritt PH,Ell PJ

    更新日期:1994-08-01 00:00:00

  • Formulation and characterization of lutetium-177-labeled stannous (tin) colloid for radiosynovectomy.

    abstract:OBJECTIVE:Easy large-scale production, easy availability, cost-effectiveness, long half-life, and favorable radiation characteristics have made lutetium-177 (Lu) a preferred radionuclide for use in therapy. Lutetium-177-labeled stannous (Lu-Sn) colloid particles were formulated for application in radiosynovectomy, foll...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000684

    authors: Arora G,Singh M,Jha P,Tripathy S,Bal C,Mukherjee A,Shamim SA

    更新日期:2017-07-01 00:00:00

  • Cell uptake and tissue distribution of radioiodine labelled D-luciferin: implications for luciferase based gene imaging.

    abstract::Optical luciferase gene imaging is emerging as a method to monitor gene expression in small animals. However, there is concern over how regional availability of exogenously administered substrate may affect photon emission. We thus synthesized [125I]iodo-D-luciferin, which demonstrated substrate characteristics for fi...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200309000-00009

    authors: Lee KH,Byun SS,Paik JY,Lee SY,Song SH,Choe YS,Kim BT

    更新日期:2003-09-01 00:00:00

  • Clinical evaluation of hypertrophic cardiomyopathy by myocardial scintigraphy using 123I-labelled 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (123I-BMIPP).

    abstract::To evaluate the clinical utility of 123I-labelled 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (123I-BMIPP), myocardial scintigraphy using 123I-BMIPP was performed in 13 patients with hypertrophic cardiomyopathy (HCM), and the findings were compared with those of 201Tl. The uptake of each tracer was scored visual...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199406000-00008

    authors: Ohtsuki K,Sugihara H,Umamoto I,Nakamura T,Nakagawa T,Nakagawa M

    更新日期:1994-06-01 00:00:00

  • Challenges for nuclear medicine in the 1990s.

    abstract::This article discusses the problems facing nuclear medicine in the coming decade and outlines the areas in which new developments or expansion can be expected. The questions considered include legislative requirements, the need to educate the public and the medical profession on the strengths of nuclear medicine, appr...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Ell PJ

    更新日期:1992-02-01 00:00:00

  • Diagnostic and prognostic impact of fluorine-18-fluorodeoxyglucose PET/CT in preoperative and postoperative setting of breast cancer patients.

    abstract:PURPOSE:The aim of this study was to assess the diagnostic and prognostic value of fluorine-18-fluorodeoxyglucose (F-FDG) PET/CT in patients with breast cancer (BC) in the preoperative and the postoperative setting. PATIENTS AND METHODS:Between 2011 and 2015, we prospectively enrolled 275 patients (mean age: 53 years)...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000671

    authors: Evangelista L,Cervino AR,Michieletto S,Saibene T,Ghiotto C,Guarneri V,Conte P,Reccia P,Saladini G

    更新日期:2017-06-01 00:00:00

  • Evaluation of local bone turnover in painful hip by 18F-fluoride positron emission tomography.

    abstract:OBJECTIVE:The diagnosis of painful hip without remarkable radiographic findings is still challenging. In recent years, femoroacetabular impingement (FAI) has been recognized as an important cause of painful hip. The hypothesis of this study was that local bone turnover may be accelerated in painful hip, especially in F...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0000000000000456

    authors: Kobayashi N,Inaba Y,Tezuka T,Ike H,Kubota S,Kawamura M,Saito T

    更新日期:2016-04-01 00:00:00

  • Experimental evaluation of the usefulness of 201Tl-chloride scintigraphy for monitoring radiotherapeutic effects.

    abstract::The level of Na(+)-K+ adenosine triphosphatase (ATPase) has been demonstrated to be correlated with tumour growth potential, and accelerated active transport of K+ carried out by Na(+)-K+ ATPase is said to be a trigger of 201Tl affinity for malignant tumour cells. Therefore, 201Tl scintigraphy appears to be a good ind...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199403000-00002

    authors: Suga K,Nishigauchi K,Fujita T,Nakanishi T

    更新日期:1994-03-01 00:00:00