Abstract:
:A new radiopharmaceutical for hepatobiliary scanning, 99Tcm Iodida, which has significant advantages in patients with high bilirubinaemia, was used to assess biliary tract complications in 30 consecutive liver transplant patients. There was adequate hepatic extraction and excretion for diagnostic imaging even in patients with serum bilirubin levels up to 877 mumol l-1 (51.6 mg dl-1). Twelve out of 12 cases (100%) without any biliary complication were correctly diagnosed. Extrahepatic obstruction was recognized in 5 out of 7 cases (71%). In one case the scintigraphic findings showed no perfusion of the transplanted liver caused by vascular thrombosis due to acute rejection. One small biliary leak was missed. The correct diagnosis of intrahepatic cholestasis was made in 3 out of 9 patients. However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis. Quantitative analysis of the kinetics of 99Tcm Iodida may permit better discrimination between the wide variety of disease in the posttransplant period.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Lantsberg S,Lanchbury EE,Drolc ZAdoi
10.1097/00006231-199011000-00005subject
Has Abstractpub_date
1990-11-01 00:00:00pages
761-9issue
11eissn
0143-3636issn
1473-5628journal_volume
11pub_type
杂志文章abstract::Fractionation of 99Tcm-exametazime enables several patients doses to be prepared from one vial. To overcome the disadvantages of storage at -70 degrees C, storage at higher temperatures was investigated with replacement of stannous ions before use. Kits were fractionated using a nitrogen-purged 0.9% w/v sodium chlorid...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199903000-00013
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:The diagnosis of painful hip without remarkable radiographic findings is still challenging. In recent years, femoroacetabular impingement (FAI) has been recognized as an important cause of painful hip. The hypothesis of this study was that local bone turnover may be accelerated in painful hip, especially in F...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0000000000000456
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:A lack of response to cardiac resynchronization therapy (CRT) has been reported in 20-40% of heart failure patients with left ventricular (LV) dyssynchrony who underwent treatment based on the established guidelines. The study aimed to investigate the relationship between (99m)Tc-tetrofosmin ((99m)Tc-TF) myoc...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0000000000000150
更新日期:2014-09-01 00:00:00
abstract::The purpose of this study was to validate different scintigraphic approaches for assessing acute myocardial infarctions. 201Tl, 99Tcm pyrophosphate (PPi) and combined 201Tl/99Tcm PPi tomograms were evaluated in 115 consecutive patients, in 85 of whom clinical examination revealed acute myocardial infarction. The overa...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199009000-00005
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Attempts have been made to improve the positivity of the radionuclide detection of gastroesophageal reflux (GER). The aim of this study was to examine the possible contribution of coughing as a provoking maneuver in GER scintigraphy. METHODS:One hundred and twenty-five patients (mean age: 9.2+/-3.2 years) w...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283298f90
更新日期:2009-06-01 00:00:00
abstract::Planar pulmonary scintigraphy is still regularly performed for the evaluation of pulmonary embolism (PE). However, only about 50-80% of cases can be resolved by this approach. This study evaluates the ability of tomographic acquisition (single photon emission computed tomography, SPECT) of the perfusion scan to improv...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200211000-00011
更新日期:2002-11-01 00:00:00
abstract::Radioimmunoscintigraphy (RIS) and radioimmunoguided surgery (RIGS) were assessed for their usefulness in patients with colorectal carcinoma. Twenty-nine patients (18 primary tumours, 10 with a suspicion of recurrence and one colonic diverticulitis) were studied. Radioimmunoscintigraphy was performed 48 and 72 h after ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199902000-00003
更新日期:1999-02-01 00:00:00
abstract::123I-labelled 15-(p-iodophenyl)-9-(R,S)-methylpentadecanoic acid (9MPA) is a modified long-chain fatty acid that shows some beta-oxidation. Some basic aspects of this fatty acid, including myocardial uptake, distribution, clearance and differences from 201Tl myocardial perfusion, have yet to be evaluated. An average o...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199809000-00004
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVES:Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic (18)F-fluorodeoxyglucose ((18)F-FDG) uptake. In this study, we focused on cytokines to investigate interactions during this phenomenon and clarify the significance of splenic (18)F-...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e3283595cac
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate myocardial findings of F-fluorodeoxyglucose PET/computed tomography (F-FDG PET/CT) after thoracic radiotherapy. METHODS:F-Fluorodeoxyglucose PET/CT examination was performed in 38 patients at least 4 months after radiotherapy. Patients with known cardiac diseases,...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e328362f824
更新日期:2013-09-01 00:00:00
abstract::The aim of this study was to look for regional cerebral blood flow (rCBF) abnormalities in patients with a recent diagnosis of pseudotumour cerebri (PTC) and to compare 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) cerebral single photon emission tomographic (SPET) findings with those of X-ray computed tomograph...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199608000-00009
更新日期:1996-08-01 00:00:00
abstract::Early diagnosis in Alzheimer's disease (AD) is important for the administration of new treatments. The purpose of this study was to differentiate mildly/moderately demented AD patients from normal controls by means of activational brain SPECT, and to investigate the correlation between regional cerebral blood flow and...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200008000-00010
更新日期:2000-08-01 00:00:00
abstract::Radically operated tumour patients (gastrointestinal cancer, n = 10; lung cancer, n = 10) were subjected to continuous prospective monitoring of the serum level of tissue polypeptide antigen (TPA) prior to surgical treatment as well as during the subsequent year. The following observations were made: Immediately after...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198602000-00007
更新日期:1986-02-01 00:00:00
abstract:AIM:To test the applicability of Tc-dextran joint scintigraphy in the assessment of disease activity in patients with rheumatoid arthritis (RA), and to compare it with the clinical disease activity scores and laboratory parameters. METHODS:Twenty-seven patients with RA were investigated using Tc-dextran joint scintigr...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/01.mnm.0000126632.32413.2e
更新日期:2004-06-01 00:00:00
abstract::Twelve patients with a diagnosis of schizophrenia and thirteen control subjects were injected with 77Br-bromospiperone and scanned using single photon emission tomography after 16 h. Although a statistically significant increase in patients by comparison with controls could be demonstrated, wide variations in specific...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198608000-00006
更新日期:1986-08-01 00:00:00
abstract:OBJECTIVES:This survey was designed to assess the trends in the frequencies of nuclear medicine procedures in the UK and to determine their contributions to the annual collective effective dose to the UK population. The average activities administered by nuclear medicine departments were compared with guidance on diagn...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/01.mnm.0000184939.28994.f9
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the diagnostic value of 2-(fluorine-18)-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT in comparison with MRI for the detection of recurrent ovarian cancer. METHODS:Forty-seven patients with suspected ovarian cancer recurrence after total ablative or cytoreductive surgery, ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32834fc5bf
更新日期:2012-05-01 00:00:00
abstract::Cystic fibrosis patients require pancreatic enzyme supplements to aid food digestion. It is suspected that incorrect delivery of this enzyme may result in both significant malabsorption and the development of strictures in the proximal colon caused by the high-dose supplement reaching this region before the food. Inve...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199808000-00006
更新日期:1998-08-01 00:00:00
abstract:PURPOSE:Yttrium-90 (Y)-resin microspheres are prescribed using activity. We evaluated overall survival (OS) and radiographic tumor response after selective internal radiation therapy (SIRT) with resin microspheres in patients with liver metastases from colorectal cancer. PATIENTS AND METHODS:We retrospectively reviewe...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000887
更新日期:2018-10-01 00:00:00
abstract::Chronic synovitis often occurs in people with haemophilia. Untreated chronic haemophilic synovitis affects the metabolism of chondrocytes, thus leading to haemophilic arthropathy. A recently introduced therapeutic protocol includes radiation synovectomy (RS), a safe and cost-effective therapeutic method, which has giv...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/MNM.0b013e32835ed50c
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To verify the negative predictive value of pulmonary ventilation/perfusion scintigraphy with single photon emission computed tomography (V/Q SPECT) in ruling out pulmonary thromboembolism. METHODS:V/Q SPECT using 99mTc-Technegas was performed on 584 patients to rule out pulmonary thromboembolism between Octo...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e32827a8e99
更新日期:2007-08-01 00:00:00
abstract::The results of scintigraphy in 29 patients with Cushing's syndrome were evaluated. It was possible to separate bilateral hyperplasia from unilateral abnormality. In cases of unilateral abnormality correct localization of the tumour was accomplished and it was possible to visualize adrenocortical carcinoma. The many ad...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198501000-00005
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:To prepare the rhenium-188 (188Re)-arginine-glycine-aspartic acid (RGD) peptide in a convenient manner and to evaluate its potential as an agent for alphavbeta3 integrin receptor-positive tumors. METHODS:Radiolabeled RGD was obtained by conjugating the His group at the end of peptide with fac-[188Re(H2O)3(CO...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3283334e48
更新日期:2010-02-01 00:00:00
abstract::The main aim of this study was to investigate the role of N-(2,4,6 trimethyl-3-bromophenylcarbamoylmethyl) iminodiacetic acid (IDA; Mebrofenin) scintigraphy in follow-up assessments of the biliary system in patients with cystic fibrosis associated liver disease. Fourteen patients from a study published in 1996 were re...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200207000-00012
更新日期:2002-07-01 00:00:00
abstract::The aim of this study was to determine if it is possible to exclude renal obstruction using diuresis renography in the first 6 weeks of life (the period of physiological renal immaturity), thus avoiding unnecessary invasive procedures, such as the Whitaker test or surgery. Diuresis renography with 123I-hippuran was pe...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199711000-00003
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:ECG-gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy combined with phase analysis allows for the assessment of left ventricular dyssynchrony. However, there are several software programs available thereby introducing variability in outcome and normal values. The aim ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001068
更新日期:2019-10-01 00:00:00
abstract::Ion-exchange resin beads, implanted into connective tissue, were used as the vehicle for the delivery of radiolabelled cations to determine the local distribution of lead, silver and cadmium in loose connective tissue. The system was devoid of systemic toxicity, permitted a predictable release, enabled location of rel...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198806000-00003
更新日期:1988-06-01 00:00:00
abstract:PURPOSE:Extramammary Paget's disease (EMPD) is rare, and limited data have been reported on the utilization of fluorine-18 fluorodeoxyglucose PET/computed tomography ((18)F-FDG PET/CT) in this disease. The aim of this study is to evaluate the role of (18)F-FDG PET/CT in the diagnosis and staging of EMPD. MATERIALS AND...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000340
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:The NHS National PET-CT Audit Programme was launched in 2008 as part of a national NHS programme to widen patient access to PET-computed tomography (CT) imaging in England. However, to implement clinical audit effectively, healthcare professionals need to be fully engaged with the process. The purpose of the pi...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000161
更新日期:2014-10-01 00:00:00
abstract::Comparisons of gastric emptying between different centres are difficult because of wide variations in methods. Reproducibility of a method is very important before it is used to compare different subjects or to assess the effect of treatment. The aim of this study was to measure the reproducibility of gastric emptying...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199801000-00011
更新日期:1998-01-01 00:00:00