Utility of 18F-FDG uptake in various regions of Waldeyer's ring to differentiate benign from malignant lesions in the midline roof of the nasopharynx.

Abstract:

PURPOSE:Lymphoid hyperplasia is not uncommon in the midline roof of the nasopharynx. Most nasopharyngeal carcinoma patients present with primary tumors in the midline of the nasopharynx. The aim of this study was to evaluate the efficacy of 2-[fluorine-18] fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/computed tomography (CT) to differentiate between benign and malignant lesions in the midline roof of the nasopharynx. MATERIALS AND METHODS:The data from the (18)F-FDG PET/CT images of 4846 participants were analyzed. Visual uptake, the lesions' standard uptake values (SUVs), and any abnormalities on the PET/CT images were evaluated. RESULTS:Sixty-six individuals with benign lesions and 25 with nasopharyngeal carcinoma were included in the analysis. The participants with benign and malignant lesions displayed increased (18)F-FDG uptake (SUV; mean±SD) in the midline roof of the nasopharynx (4.16±1.92 and 6.65±2.81, respectively), with SUVs significantly differing between the two types of lesions (P<0.001). An associated increased (18)F-FDG uptake in Waldeyer's ring and the salivary glands occurred in benign but not in malignant lesions. The ratio of uptake in the midline roof of the nasopharynx and the palatine tonsil in the benign lesions (0.92±0.42) was significantly lower than that in the malignant lesions (1.76±0.93) (P<0.001). CONCLUSION:The analysis of the intensity and patterns of (18)F-FDG uptake in various regions of Waldeyer's ring provides a feasible modality for the differentiation between benign lesions and malignant nasopharyngeal midline roof lesions.

journal_name

Nucl Med Commun

authors

Chen YK,Wang SC,Cheng RH,Yeh CL,Tsui CC,Chia-Hung K

doi

10.1097/MNM.0000000000000141

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

922-31

issue

9

eissn

0143-3636

issn

1473-5628

journal_volume

35

pub_type

临床试验,杂志文章
  • Pharmacokinetics, biodistribution and dosimetry of 99Tcm(V)DMSA in humans with squamous cell carcinoma.

    abstract::Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to evaluate squamous carcinoma (SCC) of the head and neck. This study evaluated the pharmacokinetics and biodistribution of 99Tcm(V)DMSA in patients with SCC and calculated the bone mass of a New Zealand White (N...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199005000-00002

    authors: Watkinson JC,Allen S,Lazarus CR,Sinclair J,Blake GM,Clarke SE

    更新日期:1990-05-01 00:00:00

  • Nuclear cardiology in the UK: British Nuclear Cardiology Society survey 1994.

    abstract::This study surveyed practice in nuclear cardiology in the UK in 1994. A questionnaire was sent to 219 centres performing nuclear imaging asking for details of current practice in nuclear cardiology. Replies were received from 192 centres (88%). Activity in performance of myocardial perfusion imaging (MPI) and radionuc...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199804000-00004

    authors: Pennell DJ,Prvulovich E,Tweddel A,Caplin J

    更新日期:1998-04-01 00:00:00

  • Different fibrovascularization rate between coralline hydroxyapatite and high density porous polyethylene (Medpore) measured by 99mTc-MDP bone scintigraphy 6 months after intraorbital implantation.

    abstract::Many materials and types of implant have been used to achieve a cosmetic effect and prosthesis motility in the anophthalmic socket. Hydroxyapatite remains the implant material of choice for producing the most natural prosthesis motility while porous polyethylene shows promising characteristics as another useful materi...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200312000-00006

    authors: Pan MH,Wu YW,Yen RF,Tzen KY,Liao SL,Kao CH

    更新日期:2003-12-01 00:00:00

  • 18F-Fluorodeoxyglucose PET/CT and dynamic contrast-enhanced MRI as imaging biomarkers in malignant pleural mesothelioma.

    abstract:PURPOSE:The purpose of this study was to compare the use of fluorine-18-fluorodeoxyglucose (F-FDG) PET with computed tomography (CT) and dynamic contrast-enhanced (DCE) MRI to predict prognosis and monitor treatment in malignant pleural mesothelioma. PATIENTS AND METHODS:F-FDG PET/CT and DCE-MRI studies carried out as...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0000000000000789

    authors: Hall DO,Hooper CE,Searle J,Darby M,White P,Harvey JE,Braybrooke JP,Maskell NA,Masani V,Lyburn ID

    更新日期:2018-02-01 00:00:00

  • Incidence, severity and clinical course of right ventricular involvement after acute inferior myocardial infarction; assessment by sequential 99Tcm-pyrophosphate scan and gated blood pool scan.

    abstract::To evaluate the incidence, severity and clinical course of right ventricular (RV) involvement after acute inferior myocardial infarction (IMI), 78 patients (pts) with IMI were investigated by both 99Tcm-pyrophosphate (PYP) scan and gated blood pool scan (GBPS). GBPS was performed at admission and 10 days, whereas 99Tc...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198612000-00007

    authors: Nishimura T,Yasuda T,Gold HK,Leinbach RC,Boucher CA,McKusick KA,Strauss HW

    更新日期:1986-12-01 00:00:00

  • Bone marrow scintigraphy in small cell carcinoma of the lung.

    abstract::A comparative study of bone marrow scintigraphy using 99Tcm-nanocolloid, conventional bone scintigraphy and bone marrow biopsy were performed in 35 patients with histologically proven small cell carcinoma of the lung to determine whether bone marrow scintigraphy has a role in the early detection of bone marrow metasta...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199401000-00006

    authors: Li DJ,Maughan TS,Miles KA,Wraight EP

    更新日期:1994-01-01 00:00:00

  • Comparison between visual and numerical metrics for the evaluation of patients with Takayasu arteritis with 18F-FDG-PET.

    abstract:INTRODUCTION:The choice of metrics for defining active Takayasu arteritis (TAK) using fluorine-18-fluorodeoxyglucose (F-FDG)-PET remains controversial. OBJECTIVE:The aim of this study was to compare in the same patients the diagnostic performance for the detection of active TAK of different metrics applied for the qua...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000867

    authors: Emsen B,Benali K,Mahida B,Larivière D,Le Guludec D,Papo T,Sacre K,Hyafil F

    更新日期:2018-08-01 00:00:00

  • Hybrid lymph node imaging using 64Cu-labeled mannose-conjugated human serum albumin with and without indocyanine green.

    abstract:OBJECTIVE:Human serum albumin (HSA), which has 58 Lys residues, one Cys residue, and indocyanine green (ICG) adsorption sites, can be used as a multifunctional platform for the development of hybrid imaging probes. In this study, we prepared 64Cu-labeled mannose-conjugated HSA with and without ICG ([64Cu]1-ICG and [64C...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000353

    authors: Kang CM,An GI,Choe YS

    更新日期:2015-10-01 00:00:00

  • Accuracy of gated equilibrium radioventriculography in measuring left ventricular function in dogs.

    abstract::To assess the precision of gated equilibrium radioventriculography in measuring changes in left ventricular stroke volume (LVSV), we studied five dogs each with a chronically implanted electromagnetic flowmeter on the ascending aorta. Per cent changes in left ventricular stroke counts (LVSC) were compared to those in ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198812000-00009

    authors: Valette H,Bourguignon MH,Apoil E,Moyse D,Wise RA,Buchanan JW,Wagner HN Jr,Syrota A

    更新日期:1988-12-01 00:00:00

  • Specifying dual-detector gamma cameras and associated computer systems.

    abstract::Increasingly, dual-detector gamma cameras are being purchased as replacements for single-headed cameras. The improvement in sensitivity offered by a dual-detector device can be used in several ways: to shorten acquisition times, to improve signal-to-noise ratios, or to reduce administered doses. This paper focuses on ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,评审

    doi:10.1097/00006231-199507000-00003

    authors: Tindale WB

    更新日期:1995-07-01 00:00:00

  • Optimizing an 18F-NaF and 18F-FDG cocktail for PET assessment of metastatic castration-resistant prostate cancer.

    abstract:BACKGROUND:PET/computed tomography (CT) imaging with the sodium-(F)-fluoride/2-(F)-fluoro-2-deoxy-D-glucose (F-NaF/F-FDG) cocktail has been proposed for patients with osseous metastases. This work aimed to optimize the cocktail composition for patients with metastatic castration-resistant prostate cancer (mCRPC). MATE...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000383

    authors: Simoncic U,Perlman S,Liu G,Jeraj R

    更新日期:2015-12-01 00:00:00

  • Dual isotope brain SPECT imaging for monitoring cognitive activation: physical considerations.

    abstract::The physical considerations of using dual isotope brain SPECT imaging to monitor blood flow changes during cognitive activation studies were investigated. These factors included field uniformity, spatial resolution and crosstalk. Serial dual isotope single photon emission computed tomographic (SPECT) studies of a test...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199305000-00008

    authors: Madsen MT,O'Leary DS,Andreasen NC,Kirchner PT

    更新日期:1993-05-01 00:00:00

  • In-vivo quantification of dose-dependent dopamine transporter blockade in the rat striatum with small animal SPECT.

    abstract:OBJECTIVE:This study investigated dopamine transporter blockade in the rat striatum after treatment with various doses of methylphenidate using a high-resolution small animal SPECT ('TierSPECT') and I-FP-CIT. METHODS:I-FP-CIT was administered intravenously 1 h after intraperitoneal injection of methylphenidate (3 mg.k...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e328014a0df

    authors: Nikolaus S,Antke C,Beu M,Kley K,Larisch R,Wirrwar A,Müller HW

    更新日期:2007-03-01 00:00:00

  • 99Tcm-DMSA renal scintigraphy for acute pyelonephritis in adults: planar and/or SPET imaging?

    abstract::A number of authors have indicated a more sensitive detection of renal cortical defects using single photon emission tomography (SPET) compared with planar imaging when performing 99Tcm-dimer-captosuccinic acid (99Tcm-DMSA) renal scintigraphy. The place of SPET in the evaluation of kidneys in adults suspected of acute...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Everaert H,Flamen P,Franken PR,Peeters P,Bossuyt A,Piepsz A

    更新日期:1996-10-01 00:00:00

  • Uptake of 123I-5-iodo-2-thiouracil, a possible radiopharmaceutical for noninvasive detection of ocular melanoma, in melanotic and amelanotic melanomas in hamsters.

    abstract::The uptake of 123I-5-iodo-2-thiouracil in melanotic and amelanotic melanoma implanted in Syrian golden hamsters was studied. A selective accumulation was found in the tumours. Uptake of 123ITU in melanotic melanomas was 4 to 5 times the uptake in amelanotic ones. For both tumours high ratios of tumours versus non-tumo...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198510000-00007

    authors: Franken NA,Van Langevelde A,Journée-De Korver JG,Bakker CN,Feitsma RI,Van Delft JL,Oosterhuis JA,Pauwels EK

    更新日期:1985-10-01 00:00:00

  • Relationship between positive thyroglobulin doubling time and 18F-FDG PET/CT-positive, 131I-negative lesions.

    abstract:AIM:In patients with differentiated thyroid carcinoma (DTC), metastases can either show iodine-131 (I) uptake on whole-body scintigraphy or F-2-fluoro-2-deoxy-D-glucose (F-FDG) uptake on combined PET and X-ray computed tomography (PET/CT), or a mix of both. The present study investigates the relationship between uptake...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000025

    authors: Kelders A,Kennes LN,Krohn T,Behrendt FF,Mottaghy FM,Verburg FA

    更新日期:2014-02-01 00:00:00

  • Abdominal scintigraphy with 99Tcm-labelled red cells in the detection of rebleeding from peptic ulcers.

    abstract::The technique of 99Tcm-labelled red cell scintigraphy as a means of detecting rebleeding was investigated in 33 patients with bleeding peptic ulcers. Scintigrams were performed twice during the 24 h period succeeding diagnostic endoscopy. There was scintigraphic evidence of rebleeding in 23 patients but this was clini...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198509000-00003

    authors: Kinnear WJ,Dickinson RJ,Buxton-Thomas M,Wraight EP

    更新日期:1985-09-01 00:00:00

  • 99mTc-HL91 is inferior to 201Tl in scintigraphic detection of chronic myocardial ischaemia.

    abstract:AIM:99mTc-HL91 is a new hypoxia agent and can identify acutely ischaemic viable myocardium in a canine model using a standard gamma camera. The purpose of the study was to determine whether this tracer could be used to detect regional ischaemia in chronic ischaemic myocardium in a swine model. METHOD:Using a porcine m...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200512000-00012

    authors: Wu YW,Lee CM,Huang YH,Chou NK,Yen RF,Tzen KY,Huang PJ

    更新日期:2005-12-01 00:00:00

  • A comparison of 18F-FDG gamma camera PET, mammography and ultrasonography in demonstrating primary disease in locally advanced breast cancer.

    abstract:BACKGROUND:Positron emission tomography (PET) imaging using [18F]fluorodeoxyglucose (18F-FDG) is recognized to have a major role in oncological imaging. Over recent years there has been a steady increase in the use of gamma camera PET (GCPET) systems as these are less expensive than dedicated PET scanners and facilitat...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.mnm.0000130239.76326.ca

    authors: Marshall C,Mustafa S,Wheatley DC,Eremin JE,El-Sheemy M,Jibril JA,Eremin O,Griffiths PA

    更新日期:2004-07-01 00:00:00

  • Dosimetric evaluation and therapeutic response to internal radiation therapy of hepatocarcinomas using iodine-131-labelled lipiodol.

    abstract:OBJECTIVE:Vectorized internal radiation therapy using lipiodol-labelled with iodine-131 (131 I-lipiodol) is an effective treatment for inoperable hepatocellular carcinomas. However, few dosimetric data are available based on this approach. We have developed a dosimetric protocol based on scintiscan imaging and that is ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32830439c6

    authors: Becker S,Laffont S,Vitry F,Rolland Y,Lecloirec J,Boucher E,Raoul JL,Herry JY,Bourguet P,Garin E

    更新日期:2008-09-01 00:00:00

  • 201Tl myocardial perfusion SPET: adenosine alone or combined with dynamic exercise.

    abstract::201Tl myocardial perfusion single photon emission tomography (SPET) with pharmacological coronary vasodilatation using adenosine is now often used in the investigation of a patient with ischaemic heart disease (IHD). In this study, we present data from two groups of patients. Group A (n = 40) experienced 201Tl SPET wi...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-199408000-00003

    authors: Mahmood S,Gupta NK,Gunning M,Bomanji JB,Jarritt PH,Ell PJ

    更新日期:1994-08-01 00:00:00

  • Reproducibility of gastric emptying of a pancake and milkshake meal in normal subjects.

    abstract::Comparisons of gastric emptying between different centres are difficult because of wide variations in methods. Reproducibility of a method is very important before it is used to compare different subjects or to assess the effect of treatment. The aim of this study was to measure the reproducibility of gastric emptying...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199801000-00011

    authors: Kong MF,Perkins AC,King P,Blackshaw PE,Macdonald IA

    更新日期:1998-01-01 00:00:00

  • Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET.

    abstract:OBJECTIVES:The aim of this study was to evaluate the usefulness of (123)I-iomazenil (IMZ) single photon emission computed tomography (SPECT) for the pre-surgical identification of epileptogenic areas in patients with temporal lobe epilepsy and to compare the results with those of (123)I-IMP SPECT and (18)Fluorodeoxyglu...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/01.mnm.0000243380.79872.32

    authors: Kaneko K,Sasaki M,Morioka T,Koga H,Abe K,Sawamoto H,Ohya N,Yoshiura T,Mihara F,Honda H

    更新日期:2006-11-01 00:00:00

  • Emptying effect of massage on parotid gland radioiodine content.

    abstract:BACKGROUND:To prevent salivary dysfunction in thyroid cancer patients who have undergone radioiodine ablation, massaging the parotid gland (PG) is presumed to be helpful for the removal of radioiodine. The purpose of this study was to evaluate the effect of PG massage in the removal of radioiodine from the PG. METHODS...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MNM.0000000000000176

    authors: Hong CM,Son SH,Kim CY,Kim DH,Jeong SY,Lee SW,Lee J,Ahn BC

    更新日期:2014-11-01 00:00:00

  • Metastatic differentiated thyroid carcinoma: clinical management and outcome of disease in patients with initial and late distant metastases.

    abstract:OBJECTIVE:Our objective was to analyze the clinical management and the outcome of disease in differentiated thyroid carcinoma with initial and late distant metastases (M1). PATIENTS AND METHODS:Radioiodine (131I) therapy was applied in 77 differentiated thyroid carcinoma patients with M1 (31 patients with M1-initial a...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32832cc2ab

    authors: Mihailovic JM,Stefanovic LJ,Malesevic MD,Erak MD,Tesanovic DD

    更新日期:2009-07-01 00:00:00

  • Quantitative assessment of cardiac mechanical dyssynchrony and prediction of response to cardiac resynchronization therapy in patients with nonischaemic dilated cardiomyopathy using gated myocardial perfusion SPECT.

    abstract:OBJECTIVE:The aim of the study was to evaluate gated myocardial perfusion SPECT (GMPS) in the prediction of response to cardiac resynchronization therapy (CRT) in nonischaemic dilated cardiomyopathy patients. PATIENTS AND METHODS:Thirty-two patients (23 men, mean age 57.5±12.1 years) with severe heart failure, who wer...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0000000000000282

    authors: Mukherjee A,Patel CD,Naik N,Sharma G,Roy A

    更新日期:2015-05-01 00:00:00

  • Prognostic value of dual-point fluorine-18 fluorodeoxyglucose PET imaging, partial volume correction and glucose transporter-1 expression in resected nonsmall cell lung cancer patients.

    abstract:OBJECTIVE:To investigate the relationship between the prognosis and glucose transporter-1 (Glut-1) expression or fluorine-18 fluorodeoxyglucose uptake using partial volume correction and dual-point imaging in surgically resected nonsmall cell lung cancer (NSCLC) patients. METHODS:Our patient population consisted of 10...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001118

    authors: Kaida H,Azuma K,Kawahara A,Takamori S,Akiba J,Fujimoto K,Ishii K,Ishibashi M

    更新日期:2020-01-01 00:00:00

  • Bone marrow uptake of indolent non-Hodgkin lymphoma on PET/CT with histopathological correlation.

    abstract:OBJECTIVE:To evaluate the diagnostic accuracy of PET/computed tomography (CT) in detecting marrow infiltration in indolent non-Hodgkin lymphoma (NHL) with histopathological correlation. METHODS:All treatment-naive newly diagnosed indolent NHL with staging PET/CT were retrospectively evaluated for marrow infiltration a...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000361

    authors: Lee EY,Gill H,Wang Y,Kwong YL,Khong PL

    更新日期:2015-10-01 00:00:00

  • UK audit of single photon emission computed tomography reconstruction software using software generated phantoms.

    abstract::The purpose of this study was to undertake an audit of the quantitative characteristics of single photon emission computed tomography software using projection data from an analytically generated software phantom and a measured line source. The phantom consisted of three structures. A uniformly filled cylinder, a seri...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200205000-00009

    authors: Jarritt PH,Whalley DR,Skrypniuk JV,Houston AS,Fleming JS,Cosgriff PS

    更新日期:2002-05-01 00:00:00

  • Challenges for nuclear medicine in the 1990s.

    abstract::This article discusses the problems facing nuclear medicine in the coming decade and outlines the areas in which new developments or expansion can be expected. The questions considered include legislative requirements, the need to educate the public and the medical profession on the strengths of nuclear medicine, appr...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Ell PJ

    更新日期:1992-02-01 00:00:00