Double-tracer SPECT in patients with AIDS encephalopathy: a comparison of 123I-IMP with 99Tcm-HMPAO.

abstract：OBJECTIVE:This study investigated dopamine transporter blockade in the rat striatum after treatment with various doses of methylphenidate using a high-resolution small animal SPECT ('TierSPECT') and I-FP-CIT. METHODS:I-FP-CIT was administered intravenously 1 h after intraperitoneal injection of methylphenidate (3 mg.k...

journal_title：Nuclear medicine communications

authors： Nikolaus S,Antke C,Beu M,Kley K,Larisch R,Wirrwar A,Müller HW

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....

journal_title：Nuclear medicine communications

authors： Lin WY,Tsai SC,Hung GU

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The widely applied F-FDG is known for its disadvantage in brain tumour PET imaging because of its high background uptake. C-choline can achieve high contrast of brain tumour imaging and was expected to have higher sensitivity and specificity. We analysed the misdiagnoses in C-choline PET imagin...

journal_title：Nuclear medicine communications

authors： Huang Z,Zuo C,Guan Y,Zhang Z,Liu P,Xue F,Lin X

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:The aim of this prospective study was to assess the influence of different normalization procedures on relative changes in standardized uptake values (SUV) of F-2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) for the assessment of chemotherapy response in patients with colorectal carcinoma ...

journal_title：Nuclear medicine communications

authors： Vriens D,de Geus-Oei LF,van Laarhoven HW,Timmer-Bonte JN,Krabbe PF,Visser EP,Oyen WJ

更新日期：2009-07-01 00:00:00

abstract：:The main aim of this study was to investigate the role of N-(2,4,6 trimethyl-3-bromophenylcarbamoylmethyl) iminodiacetic acid (IDA; Mebrofenin) scintigraphy in follow-up assessments of the biliary system in patients with cystic fibrosis associated liver disease. Fourteen patients from a study published in 1996 were re...

journal_title：Nuclear medicine communications

authors： Foster JA,Ramsden WH,Conway SP,Taylor JM,Etherington C

更新日期：2002-07-01 00:00:00

abstract：INTRODUCTION:The metabotropic glutamate receptor subtype 5 (mGluR5) is distributed throughout the central nervous system (CNS), and has been suggested to be a potential target for several CNS disorders suchas Parkinson's disease, pain, anxiety, depression, schizophrenia, and addiction. We report here on the rhesus monk...

journal_title：Nuclear medicine communications

authors： Bélanger MJ,Krause SM,Ryan C,Sanabria-Bohorquez S,Li W,Hamill TG,Burns HD

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate myocardial findings of F-fluorodeoxyglucose PET/computed tomography (F-FDG PET/CT) after thoracic radiotherapy. METHODS:F-Fluorodeoxyglucose PET/CT examination was performed in 38 patients at least 4 months after radiotherapy. Patients with known cardiac diseases,...

journal_title：Nuclear medicine communications

authors： Unal K,Unlu M,Akdemir O,Akmansu M

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:The NHS National PET-CT Audit Programme was launched in 2008 as part of a national NHS programme to widen patient access to PET-computed tomography (CT) imaging in England. However, to implement clinical audit effectively, healthcare professionals need to be fully engaged with the process. The purpose of the pi...

journal_title：Nuclear medicine communications

authors： Ross P,Hubert J,Saunders M,Wong WL

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the incremental value of technetium-99m-methylene diphosphonate (99mTc-MDP) single-photon emission tomography/computed tomography (SPECT/CT) over planar bone scintigraphy (BS) and SPECT in the diagnosis of avascular necrosis (AVN) of the femoral head. MATERIALS AND METHOD...

journal_title：Nuclear medicine communications

authors： Agarwal KK,Mukherjee A,Sharma P,Bal C,Kumar R

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) and its relationship with several metabolic parameters obtained through PET in intrahepatic cholangiocarcinoma (ICC) submitted to radioembolization with Y-microspheres (Y-radioembolization). METHODS:Records ...

journal_title：Nuclear medicine communications

authors： Filippi L,Di Costanzo GG,Tortora R,Pelle G,Saltarelli A,Marino Marsilia G,Cianni R,Schillaci O,Bagni O

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the cerebral amyloid distribution in patients with mild cognitive impairment (MCI), assessed by carbon-11-Pittsburgh compound B (C-PIB) PET/CT, after 5 years of follow-up. PATIENTS AND METHODS:Ten amnestic MCI (A-MCI) and four nonamnestic (NA-MCI) patients were studied b...

journal_title：Nuclear medicine communications

authors： Jiménez-Bonilla JF,Quirce R,De Arcocha-Torres M,Martínez-Rodríguez I,Martínez-Amador N,Sánchez-Salmón A,De la Fuente-Gómez F,Rodríguez E,Sánchez-Juan P,Banzo I

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Neurokinin 1 (NK1) receptors have been implicated in depression, anxiety, and pain perception. Recently, it was shown that, in the human brain, a specific NK1 receptor-related signal was obtained with the novel radioligand, [¹¹C]R116301, using positron emission tomography. The purpose of this study was to evalu...

journal_title：Nuclear medicine communications

authors： Wolfensberger SP,Maruyama K,van Berckel BN,Lubberink M,Airaksinen AJ,Boellaard R,Luurtsema G,Reddingius W,Janssens FE,Veltman DJ,Windhorst AD,Leysen JE,Lammertsma AA

更新日期：2011-10-01 00:00:00

abstract：:LL1, a monoclonal antibody (MAb) to HLA Class-II-like antigen (li determinant) on the surface of B-lymphocytes, monocytes and histiocytes, was evaluated as an agent for bone marrow imaging. Six patients with diverse diseases (non-Hodgkin's lymphoma, n = 2; multiple myeloma, n = 1; polycythaemia vera, n = 1; lung cance...

journal_title：Nuclear medicine communications

authors： Juweid M,Dunn RM,Sharkey RM,Rubin AD,Hansen HJ,Goldenberg DM

更新日期：1997-02-01 00:00:00

abstract：:Simultaneous assessment of regional adrenergic activity and perfusion with 123I-meta-iodobenzylguanidine (123I-MIBG) and 201Tl in various organs was performed in 13 patients with congestive heart failure (CHF) and 13 subjects without heart failure. In order to reduce the crosstalk of 201Tl to the 123I energy window to...

journal_title：Nuclear medicine communications

authors： Seto H,Shimizu M,Nozawa T,Yoshida N,Inagaki S,Kageyama M,Kakishita M

更新日期：1996-03-01 00:00:00

abstract：:Radioiodinated meta-iodobenzylguanidine (MIBG) is used routinely for imaging and targeted radiotherapy of tumours derived from the neural crest. Since active uptake of MIBG by the noradrenaline transporter (NAT) makes a greater contribution to total drug accumulation than passive uptake when MIBG is present at low con...

journal_title：Nuclear medicine communications

authors： Owens J,Bolster AA,Prosser JE,Cunningham S,Mairs RJ,Neilly JB,Reed NS,Hilditch TE

更新日期：2000-05-01 00:00:00

abstract：:Our aim was to determine whether the Ca2+ ion or cell membrane Ca2+ and Na+/Ca2+ ion transport systems are involved in maintaining the cell-associated activity of technetium-99m-hexakis-methoxy-isobutyl-isonitrile (99mTc-MIBI) and technetium-99m-ethylene-bis[bis(2-ethoxyethyl)phosphin] (99mTc-tetrofosmin) in tumour ce...

journal_title：Nuclear medicine communications

authors： Arbab AS,Ueki J,Koizumi K,Araki T

更新日期：2003-02-01 00:00:00

abstract：:It is possible to obtain an estimate of the bone uptake of diphosphonates after 3 h (BU) on the basis of the difference between the dose administered and the sum of the component eliminated in the urine plus the component present in the extra-osseous volume of distribution. The results of this simple method have been ...

journal_title：Nuclear medicine communications

authors： Galli G,Bagnato A,Galli M

更新日期：1995-09-01 00:00:00

abstract：AIM:This study was undertaken to evaluate different methods for the detection of small changes in uptake between single-photon emission computed tomography (SPECT) examinations in the same individual. No standard exists for making digital evaluations at single-photon examinations. For this purpose, we employed a patien...

journal_title：Nuclear medicine communications

authors： Jacobsson H,Wilczek B,Bergh J,von Schoultz E,Eriksson E,Larsson SA

更新日期：2006-04-01 00:00:00

abstract：:The time course of thyroglobulin (Tg) was monitored in patients with differentiated thyroid carcinoma after ablative therapy (thyroidectomy + 131I-treatment) with particular respect to endogeneous antibodies (Tg-ABs). In 232 patients (196 without Tg-ABs, 36 with Tg-ABs at the time of treatment) a sensitivity of 88% (a...

journal_title：Nuclear medicine communications

authors： Moser E,Braun S,Kirsch CM,Kleinhans E,Buell U

更新日期：1984-05-01 00:00:00

abstract：:Medullary thyroid carcinoma (MTC) is a neuroendocrine tumour characterized by the production and secretion of calcitonin. MTC tumours may express functional somatostatin receptors (hSSTR). A significant proportion of hSSTR receptor-positive MTC tumours, including metastatic disease, may be visualized in vivo through 1...

journal_title：Nuclear medicine communications

authors： O'Byrne KJ,O'Hare N,Sweeney E,Freyne PJ,Cullen MJ

更新日期：1996-09-01 00:00:00

abstract：:The viability of autologous adrenal medullary transplants was evaluated using 125I-meta-iodobenzyl guanidine (MIBG), an adrenal medullary scanning agent. Bilateral cavities in the caudate nuclei were made stereotaxically in Wistar rats. One week later, the left adrenal medulla was resected by microsurgery, followed by...

journal_title：Nuclear medicine communications

authors： Shinoda M,Suzuki Y,Oi S,Tsugane R,Sato O

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To verify the negative predictive value of pulmonary ventilation/perfusion scintigraphy with single photon emission computed tomography (V/Q SPECT) in ruling out pulmonary thromboembolism. METHODS:V/Q SPECT using 99mTc-Technegas was performed on 584 patients to rule out pulmonary thromboembolism between Octo...

journal_title：Nuclear medicine communications

authors： Leblanc M,Leveillée F,Turcotte E

更新日期：2007-08-01 00:00:00

abstract：AIM:To evaluate the biodistribution, internal radiation dosimetry and toxicity of the humanized MAb h-R3 labelled with Tc in humans. METHODS:Twenty-five patients with suspected epithelial-derived tumours were included in this study and divided into two groups: group I consisted of 10 patients who received 3 mg/1110 MB...

journal_title：Nuclear medicine communications

authors： Torres LA,Perera A,Batista JF,Hernández A,Crombet T,Ramos M,Neninger E,Pérez M,Sánchez EL,Romero S,Aguilar V,Coca MA,Iznaga-Escobar N

更新日期：2005-12-01 00:00:00

abstract：:Dynamic penile scintigraphy was performed using 99Tcm-labelled autologous erythrocytes in five normally potent volunteers and 22 patients with erectile dysfunction including 11 patients with psychogenic and 11 patients with vasculogenic impotence (four arteriogenic, three venogenic, three arteriogenic and venogenic, o...

journal_title：Nuclear medicine communications

authors： Siraj QH,Hilson AJ,Bomanji J,Ahmed M

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...

journal_title：Nuclear medicine communications

authors： Zhang Y,He J,Liu G,Venderheyden JL,Gupta S,Rusckowski M,Hnatowich DJ

更新日期：2004-11-01 00:00:00

abstract：:The application of a Well-type germanium semiconductor detector creates new possibilities in erythrocyte survival studies. Using 51Cr, the effective dose equivalent in a standard procedure can be reduced from approximately 780 to 2 microSv. The properties of the detector, namely, high efficiency and high energy resolu...

journal_title：Nuclear medicine communications

authors： De Vries RA,Oldenburg SJ,Thelosen T,De Bruin M,Poortman J,Van de Wiel A

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Chronic low serum vitamin D concentrations are common among the elderly. Recent studies have suggested that its metabolite, 25-hydroxyvitamin D (25-OHD), might be important for preserving cognitive functions through specific brain protective effects. However, this hypothesis is still under discussion. The ai...

journal_title：Nuclear medicine communications

authors： Farid K,Volpe-Gillot L,Petras S,Plou C,Caillat-Vigneron N,Blacher J

更新日期：2012-10-01 00:00:00

abstract：:Changes in regional ejection fraction (rEF) of the interventricular septum following coronary artery bypass graft (CABG) surgery were examined using first-pass radionuclide ventriculography (RNVG) in patients without objective evidence of postoperative myocardial infarction (MI). One hundred and one patients had pre- ...

journal_title：Nuclear medicine communications

authors： Jacobson AF,Tow DE,Lapsley D,Khuri S

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:Nuclear medicine procedures are often performed in close-time proximity to bone densitometry studies. The purpose of this study was to determine the effects of Tc-hexakis-2-methoxyisobutyl isonitrile (MIBI) and Tc-methylene diphosphonate (MDP) on the accuracy of bone mineral density (BMD) measurements perform...

journal_title：Nuclear medicine communications

authors： Gumuser G,Parlak Y,Topal G,Aras F,Ruksen E,Sayit E

更新日期：2009-06-01 00:00:00

abstract：:The administration of radionuclide therapies presents significant radiation protection challenges. The aim of this work was to develop a delivery system for intravenous radioisotope therapies to substantially moderate radiation exposures to staff and operators. A novel device (InfuShield) was designed and tested befor...

journal_title：Nuclear medicine communications

authors： Rushforth DP,Pratt BE,Chittenden SJ,Murray IS,Causer L,Grey MJ,Gear JI,Du Y,Flux GD

更新日期：2017-03-01 00:00:00