99Tcm-LL1: a potential new bone marrow imaging agent.

abstract：OBJECTIVE:Our objective was to analyze the clinical management and the outcome of disease in differentiated thyroid carcinoma with initial and late distant metastases (M1). PATIENTS AND METHODS:Radioiodine (131I) therapy was applied in 77 differentiated thyroid carcinoma patients with M1 (31 patients with M1-initial a...

journal_title：Nuclear medicine communications

authors： Mihailovic JM,Stefanovic LJ,Malesevic MD,Erak MD,Tesanovic DD

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:Lymphoid hyperplasia is not uncommon in the midline roof of the nasopharynx. Most nasopharyngeal carcinoma patients present with primary tumors in the midline of the nasopharynx. The aim of this study was to evaluate the efficacy of 2-[fluorine-18] fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/computed tomography (C...

journal_title：Nuclear medicine communications

authors： Chen YK,Wang SC,Cheng RH,Yeh CL,Tsui CC,Chia-Hung K

更新日期：2014-09-01 00:00:00

abstract：:The method described by Weisner et al. for stabilizing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) with cobalt chloride hexahydrate solution is the most promising developed to date. The aim of our work was to study the behaviour of cobalt during the labelling of leukocytes with 99Tcm-HMPAO stabilized in vitro ...

journal_title：Nuclear medicine communications

authors： Prangere T,Bowden AD,Beauchat V,Caulier MT,Ziegels P,Huglo D,Pickett RD,Steinling M

更新日期：1997-03-01 00:00:00

abstract：AIM AND PURPOSE:Radionuclide imaging of the kidneys using dimercaptosuccinic acid chelate labeled with technetium-99m (Tc-DMSA) is a well-established method for evaluating the extent of kidney parenchymal involvement in the scenario of urinary tract infection and for the estimation of the functional renal mass. We have...

journal_title：Nuclear medicine communications

authors： Gorenberg M,Radan L,Kosakov R,Amirav I

更新日期：2010-07-01 00:00:00

abstract：:Forty-four patients with symptoms of lower limb arterial insufficiency were examined by radionuclide angiography using 99Tcm in vivo red cell labelling and by contrast aortography. The results of the study indicate that radionuclide angiography may well have a useful role to play in determining the type of contrast st...

journal_title：Nuclear medicine communications

authors： Grime JS,Critchley M,Whitehouse GH,Zavras G

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Stunning of thyroid remnants after diagnostic scanning (Dx-WBS) using radioactive iodine- (¹³¹I) may limit the efficacy of I therapy. We aimed to evaluate this assumption in a prospectively designed study. METHODS:Forty patients who underwent thyroidectomy for differentiated thyroid carcinoma were studied and ...

journal_title：Nuclear medicine communications

authors： Amin A,Amin M,Badwey A

更新日期：2013-08-01 00:00:00

abstract：:The presence of distant metastases is the main prognostic factor in patients with breast cancer and has a significant influence in the choice of therapy. Therefore, chest X-ray, bone scintigraphy and ultrasound of the abdomen are performed to detect distant metastases at diagnosis and follow-up. Fluorodeoxyglucose pos...

journal_title：Nuclear medicine communications

authors： Dose J,Bleckmann C,Bachmann S,Bohuslavizki KH,Berger J,Jenicke L,Habermann CR,Jãnicke F

更新日期：2002-09-01 00:00:00

abstract：AIM:The aim of this study was to investigate the value of cystatin C and beta-trace protein (BTP) levels in determination of the glomerular filtration rate (GFR) by accepting the technetium-99m diethylenetriamine pentaacetic acid (Tc-DTPA) method as the gold standard for GFR measurement in renal transplant patients wit...

journal_title：Nuclear medicine communications

authors： Oner AO,Aydin F,Demirelli S,Budak ES,Davran F,Akbas H,Kocak H,Suleymanlar G,Gungor F

更新日期：2014-07-01 00:00:00

abstract：:The investigation of left ventricular contractile reserve usually requires the determination of left ventricular volume, but its measurement with radionuclide angiography is difficult. The aim of this study was to determine left ventricular volume directly during exercise by the simultaneous measurement of peak exerci...

journal_title：Nuclear medicine communications

authors： Faraggi M,Cohen-Solal A,Czitrom D,Sarda L,Lebtahi R,Daou D,Petegnief Y,Gourgon R,Guludec DL

更新日期：1996-12-01 00:00:00

abstract：:There is a lack of systematic nephrographic studies on epidemic nephritis (EN). We studied 10 patients with EN using [99Tcm]MAG3 gamma camera nephrography and followed up 9 of them 22-68 days later when they had clinically recovered. Variables for renal clearance of [99Tcm]MAG3 and the retention of radioactivity in th...

journal_title：Nuclear medicine communications

authors： Paul R,Kiiliäinen H,Tarssanen L,Vorne M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....

journal_title：Nuclear medicine communications

authors： Lin WY,Tsai SC,Hung GU

更新日期：2005-04-01 00:00:00

abstract：:Venous thromboembolism (VTE) can present as deep vein thrombosis (DVT) and/or acute pulmonary embolism (PE). In fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT, 18F-FDG activity along the deep veins of the lower extremities (LE) is often observed and, unless it is associated with focal intense activity, is not conside...

journal_title：Nuclear medicine communications

authors： Zhu HJ,Hess S,Rubello D,Goris ML,Alavi A

更新日期：2016-03-01 00:00:00

abstract：:Radioiodinated meta-iodobenzylguanidine (MIBG) is used routinely for imaging and targeted radiotherapy of tumours derived from the neural crest. Since active uptake of MIBG by the noradrenaline transporter (NAT) makes a greater contribution to total drug accumulation than passive uptake when MIBG is present at low con...

journal_title：Nuclear medicine communications

authors： Owens J,Bolster AA,Prosser JE,Cunningham S,Mairs RJ,Neilly JB,Reed NS,Hilditch TE

更新日期：2000-05-01 00:00:00

abstract：:Positron emission tomography (PET) is increasingly used clinically to provide functional information on disease processes, especially in oncology using the glucose analogue 2-[18F]fluoro-2-deoxy-D-glucose (F-FDG). In the clinical setting it has become standard practice to use simplified imaging protocols compared to t...

journal_title：Nuclear medicine communications

authors： Hallett WA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:ECG-gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy combined with phase analysis allows for the assessment of left ventricular dyssynchrony. However, there are several software programs available thereby introducing variability in outcome and normal values. The aim ...

journal_title：Nuclear medicine communications

authors： Marques de Souza Filho E,Tinoco Mesquita C,Altenburg Gismondi R,de Amorim Fernandes F,Jan Verberne H

更新日期：2019-10-01 00:00:00

abstract：:In 70 patients with angiographically confirmed coronary heart disease and in 10 controls, a 4 h exercise (E) (injection of 150 MBq 99Tcm-MIBI) rest (R) (800 MBq) protocol was employed. Of these, 10 patients with 21 myocardial defects after E received a third injection 24 h after. SPECT was used to image myocardial dis...

journal_title：Nuclear medicine communications

authors： Buell U,Dupont F,Uebis R,Kaiser HJ,Kleinhans E,Reske SN,Hanrath P

更新日期：1990-02-01 00:00:00

abstract：:INTRODUTION:: [Ga]Ga-prostate specific membrane antigen (PSMA)-11 showed a clear gain in sensitivity for lesion detection in the biological recurrence of prostate cancer as compared to the standard [F]fluorocholine radiopharmaceutical. To meet the strong demand for [Ga]Ga-PSMA-11, we aimed to optimize an automated rad...

journal_title：Nuclear medicine communications

authors： Reverchon J,Khayi F,Roger M,Moreau A,Kryza D

更新日期：2020-06-18 00:00:00

abstract：BACKROUND:Human tumors show intrinsic heterogeneity and changes in phenotype during disease progression, which implies different expression levels of cell surface receptors. The research on new heterodimeric lutetium-177 (Lu)-radiopharmaceuticals interacting with two different targets on tumor cells is a strategy for i...

journal_title：Nuclear medicine communications

authors： Escudero-Castellanos A,Ocampo-García B,Ferro-Flores G,Santos-Cuevas C,Morales-Ávila E,Luna-Gutiérrez M,Isaac-Olivé K

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Cardiac syndrome X defines patients with typical angina, a positive exercise ECG stress test and angiographically documented normal coronary arteries. In previous studies, post-stress prolonged left ventricular dysfunction (PLVD) using gated SPECT (G-SPECT) had been well correlated with myocardial perfusion a...

journal_title：Nuclear medicine communications

authors： Demir H,Kahraman G,Isgoren S,Tan YZ,Kilic T,Berk F

更新日期：2008-03-01 00:00:00

abstract：:Radioactive tracer techniques using 131I- and 125I-insulin have been applied to study insulin metabolism. A simple method to label human insulin with 123I to a high specific activity is described. We have used this radiotracer to study insulin kinetics in vivo in normal subjects and in two groups of diabetic patients....

journal_title：Nuclear medicine communications

authors： Sinclair AJ,Signore A,Bomanji J,Britton KE,Pozzilli P,Gale EA

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...

journal_title：Nuclear medicine communications

authors： Cohen JB,Kalinyak JE,McDougall IR

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Two ligands viz. tert-butyl dithiocarbamate (TBDTC) and methoxyisobutyl dithiocarbamate (MIBDTC), which are analogous to the tert-butyl isonitrile (TBI) and sestamibi (MIBI) ligands, were synthesized and labelled with the [99mTcN] core to evaluate their potential as myocardial agents. As these complexes have ...

journal_title：Nuclear medicine communications

authors： Mathur A,Mallia MB,Subramanian S,Banerjee S,Kothari K,Dhotare B,Sarma HD,Venkatesh M

更新日期：2005-11-01 00:00:00

abstract：:Increasingly, dual-detector gamma cameras are being purchased as replacements for single-headed cameras. The improvement in sensitivity offered by a dual-detector device can be used in several ways: to shorten acquisition times, to improve signal-to-noise ratios, or to reduce administered doses. This paper focuses on ...

journal_title：Nuclear medicine communications

authors： Tindale WB

更新日期：1995-07-01 00:00:00

abstract：:The aim of this study was to assess the feasibility of resting myocardial fatty acid metabolic imaging with 123I-beta-methyliodophenyl-pentadecanoic acid (123I-BMIPP) for the detection of patients with stable effort angina pectoris and to clarify the clinical significance of abnormal 123I-BMIPP images. Myocardial imag...

journal_title：Nuclear medicine communications

authors： Takeishi Y,Sukekawa H,Saito H,Nishimura S,Shibu T,Sasaki Y,Tomoike H

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVES:Ewing sarcoma breakpoint region 1 (EWSR1) translocation-negative tumors represent a minor portion of small round cell tumors consistent with Ewing sarcoma morphology. The purpose of this study was to differentiate EWSR1 translocation-positive tumors from EWSR1 translocation-negative tumors using PET-computed...

journal_title：Nuclear medicine communications

authors： Soffer S,Amitai MM,Weizen R,Retter A,Barshack I,Shimon O,Davidson T,Klang E

更新日期：2019-08-01 00:00:00

abstract：:Patients infected with the human immunodeficiency virus (HIV) suffer from serious and life-threatening infections. These patients often present with pyrexia but without localizing signs. Despite its high sensitivity in identifying focal infection 67Ga citrate scintigraphy lacks specificity; lymphoma and solid tumours ...

journal_title：Nuclear medicine communications

authors： Buscombe JR,Miller RF,Lui D,Ell PJ

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVE:To prepare the rhenium-188 (188Re)-arginine-glycine-aspartic acid (RGD) peptide in a convenient manner and to evaluate its potential as an agent for alphavbeta3 integrin receptor-positive tumors. METHODS:Radiolabeled RGD was obtained by conjugating the His group at the end of peptide with fac-[188Re(H2O)3(CO...

journal_title：Nuclear medicine communications

authors： Ma Y,Yu J,Han Y,Shen H,Li Z,Zhou W,Yin D

更新日期：2010-02-01 00:00:00

abstract：:Fluorine-18-sodium fluoride (F-NaF) PET/CT is a relatively new and high-resolution bone imaging modality. Since the use of F-NaF PET/CT has been increasing, it is important to accurately assess the images and be aware of normal distribution and major artifacts. In this pictorial review article, we will describe the no...

journal_title：Nuclear medicine communications

authors： Sarikaya I,Elgazzar AH,Sarikaya A,Alfeeli M

更新日期：2017-10-01 00:00:00

abstract：:It is generally accepted that the quality of myocardial images deteriorates with increasing patient weight. This is attributed to a reduction of counts detected from the myocardium. In this paper we have looked at the count reduction in obese patients and suggest a workable algorithm to increase the injected activity ...

journal_title：Nuclear medicine communications

authors： Notghi A,Williams N,Smith N,Goyle S,Harding LK

更新日期：2003-01-01 00:00:00

abstract：:The aim of this study was to assess, by positron emission tomography (PET), the effect on cerebral functional activity of a new lorazepam-gamma-aminobutyric acid (GABA) conjugate [3-(4-acetamido)-butyrril lorazepam (DDS2700)]. Ten healthy volunteers were studied by PET and [18F]fluoro-deoxy-D-glucose ([18F]FDG) under ...

journal_title：Nuclear medicine communications

authors： Moresco RM,Tettamanti M,Gobbo C,Del Sole A,Ravasi L,Messa C,Paulesu E,Lucignani G,Perani D,Fazio F

更新日期：2001-04-01 00:00:00