Prospective evaluation of qualitative and quantitative ¹⁸F-FDG PET-CT parameters for predicting survival in recurrent carcinoma of the cervix.

abstract：OBJECTIVE:The uptake of F-fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) is known to be linked to programmed death ligand 1 (PD-L1) expression on tumor cells (TC). However, the association between PD-L1 expression on immune cells (IC) and F-FDG accumulation is still unclear. Here, we conducted a clinicopatholo...

journal_title：Nuclear medicine communications

authors： Hu B,Xiao J,Xiu Y,Fu Z,Shi H,Cheng D

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:The goal of this study was to assess global cerebral glucose uptake in subjects with known cardiovascular risk factors by employing a quantitative F-fluorodeoxyglucose-PET/computed tomography (FDG-PET/CT) technique. We hypothesized that at-risk subjects would demonstrate decreased global brain glucose uptake co...

journal_title：Nuclear medicine communications

authors： Borja AJ,Hancin EC,Zhang V,Koa B,Bhattaru A,Rojulpote C,Detchou DK,Aly M,Kaghazchi F,Gerke O,Patil S,Gonuguntla K,Werner TJ,Revheim ME,Høilund-Carlsen PF,Alavi A

更新日期：2020-12-14 00:00:00

abstract：OBJECTIVE:This radiotherapy planning study evaluated tumour delineation using both optimally respiratory gated and nongated fluorine-18 fluorodeoxyglucose-PET (F-FDG-PET). METHODS:For 22 non-small-cell lung tumours, both scans were used to create the nongated and gated (g) gross tumour volumes (GTVg) together with the...

journal_title：Nuclear medicine communications

authors： Wijsman R,Grootjans W,Troost EG,van der Heijden EH,Visser EP,de Geus-Oei LF,Bussink J

更新日期：2016-01-01 00:00:00

abstract：:Good working practice and legal obligation impose a duty on nuclear medicine departments to check syringe activities before administration to a patient. If syringe guards are used to reduce staff exposure while drawing up injections, the guard has to be removed to measure the activity in a conventional reentrant ioniz...

journal_title：Nuclear medicine communications

authors： Hastings DL,Hillel PG,Jeans SP,Waller ML

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:Maximum standardized uptake value (SUV(max)) is a marker of tumor glucose metabolism detected by [(18)F]-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (PET/CT) and reflects tumor aggressiveness. The aim of the study was to evaluate the value of SUV(max) in differentiating benign from malignant solit...

journal_title：Nuclear medicine communications

authors： Hu SL,Yang ZY,Zhou ZR,Yu XJ,Ping B,Zhang YJ

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the clinical role of technetium-99m pertechnetate (Tc-99m) imaging in thyroidectomized differentiated thyroid cancer patients immediately before radioiodine-131 (I-131) treatment (Tx). PATIENT AND METHODS:Eighty-six consecutive post-total-thyroidectomy patients (15 men, 71...

journal_title：Nuclear medicine communications

authors： Tsai CJ,Cheng CY,Shen DH,Kuo SJ,Wang LY,Lee CH,Wang JJ,Chang MC,Huang WS

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The new anti-cancer drug imatinib mesylate inhibits the tyrosine kinase growth factor receptor, c-KIT, and has shown spectacular activity in patients with gastrointestinal stromal tumours (GISTs). OBJECTIVE:To assess whether fluorodeoxyglucose positron emission tomography (FDG PET) is suitable for response ...

journal_title：Nuclear medicine communications

authors： Jager PL,Gietema JA,van der Graaf WT

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the degree and location of the reparative process in early osteonecrosis of the femoral head on the basis of single-photon emission computed tomography/computed tomography (SPECT/CT) with technetium-99m hydroxymethylene diphosphonate. MATERIALS AND METHODS:This study was ap...

journal_title：Nuclear medicine communications

authors： Motomura G,Yamamoto T,Abe K,Nakashima Y,Ohishi M,Hamai S,Doi T,Honda H,Iwamoto Y

更新日期：2014-10-01 00:00:00

abstract：AIM:About 90% of insulinomas are benign and 5-15% are malignant. Benign insulinomas express the glucagon-like peptide-1 receptor (GLP-1R, which recognizes exendin-4 and low levels of the somatostatin receptor (SSTR, which recognizes octreotide), whereas malignant insulinomas overexpress SSTR and low levels of GLP-1R. R...

journal_title：Nuclear medicine communications

authors： Ocampo-García BE,Santos-Cuevas CL,Luna-Gutiérrez MA,Ignacio-Alvarez E,Pedraza-López M,Manzano-Mayoral C

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to assess, by positron emission tomography (PET), the effect on cerebral functional activity of a new lorazepam-gamma-aminobutyric acid (GABA) conjugate [3-(4-acetamido)-butyrril lorazepam (DDS2700)]. Ten healthy volunteers were studied by PET and [18F]fluoro-deoxy-D-glucose ([18F]FDG) under ...

journal_title：Nuclear medicine communications

authors： Moresco RM,Tettamanti M,Gobbo C,Del Sole A,Ravasi L,Messa C,Paulesu E,Lucignani G,Perani D,Fazio F

更新日期：2001-04-01 00:00:00

abstract：:Medullary thyroid cancer (MTC) originates from parafollicular C cells of the thyroid and accounts for 3-12% of all thyroid cancers. As opposed to other types of dedifferentiated thyroid tumours, MTC cells are highly functional, producing and secreting high amounts of calcitonin and carcinoembryonic antigen. As parafol...

journal_title：Nuclear medicine communications

authors： Bozkurt MF,Uğur O,Banti E,Grassetto G,Rubello D

更新日期：2008-11-01 00:00:00

abstract：:The aim of this study was to look for regional cerebral blood flow (rCBF) abnormalities in patients with a recent diagnosis of pseudotumour cerebri (PTC) and to compare 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) cerebral single photon emission tomographic (SPET) findings with those of X-ray computed tomograph...

journal_title：Nuclear medicine communications

authors： Bakar M,Tamgac F,Alper E,Zarifoglu M,Bora I,Turan F,Ogul E

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:The staging and management of patients with newly diagnosed nonsmall cell lung cancer (NSCLC) in the setting of recently diagnosed other (metachronous or synchronous) primary cancer are challenging. This retrospective cohort study was carried out to test our hypothesis that baseline 2-deoxy-2-[F]fluoro-D-gluc...

journal_title：Nuclear medicine communications

authors： Zhu X,Liao C,Penney BC,Li F,Ferguson MK,Simon CA,Wu T,Liu H,Pu Y

更新日期：2017-02-01 00:00:00

abstract：BACKROUND:Human tumors show intrinsic heterogeneity and changes in phenotype during disease progression, which implies different expression levels of cell surface receptors. The research on new heterodimeric lutetium-177 (Lu)-radiopharmaceuticals interacting with two different targets on tumor cells is a strategy for i...

journal_title：Nuclear medicine communications

authors： Escudero-Castellanos A,Ocampo-García B,Ferro-Flores G,Santos-Cuevas C,Morales-Ávila E,Luna-Gutiérrez M,Isaac-Olivé K

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the uptake of (99m)Tc-NC100668 into blood clots and elucidate the potential for medications commonly used to treat thromboembolism to interfere with the uptake and retention of (99m)Tc-NC100668. METHODS:(99m)Tc-NC100668 in vivo uptake and retention in a range of blo...

journal_title：Nuclear medicine communications

authors： Edwards D,Lewis J,Battle M,Lear R,Farrar G,Jon Barnett D,Godden V,Oliveira A,Coombes C,Ahlström H

更新日期：2007-01-01 00:00:00

abstract：:To make quantitative methods of nuclear medicine more available, four centres in Croatia participated in the national intercomparison study, following the materials and methods used in the previous international study organized by the International Atomic Energy Agency (IAEA). The study task was to calculate the activ...

journal_title：Nuclear medicine communications

authors： Grošev D,Gregov M,Wolfl MR,Krstonošić B,Debeljuh DD

更新日期：2018-08-01 00:00:00

abstract：:Most dynamic imaging protocols require long scan times that are beyond the range of what can be supported in a routine clinical environment and suffer from various difficulties related to step and shoot imaging techniques. In this short communication, we describe continuous bed motion (CBM) imaging techniques to creat...

journal_title：Nuclear medicine communications

authors： Osborne DR,Acuff S

更新日期：2016-04-01 00:00:00

abstract：:Providing information to patients and staff is an important part of the practice of nuclear medicine. To assist in improving the standard of communications, guidance has been prepared covering the content, style and presentation of letters and leaflets for patients and for medical and nursing staff. Examples are provi...

journal_title：Nuclear medicine communications

authors： Clarke SE,McKillop JH,Prescott MC,Williams ED

更新日期：1992-04-01 00:00:00

abstract：:Although several hypotheses have been suggested regarding the accumulation of 99Tc(m)-sestamibi in tumours, the exact uptake mechanism is still a matter of discussion. We investigated ultrastructural cell type of thyroid tumours by electron microscopy (EM) and compared them with uptake of 99Tc(m)-sestamibi. Thyroid sc...

journal_title：Nuclear medicine communications

authors： Sarikaya A,Huseyinova G,Irfanoğlu ME,Erkmen N,Cermik TF,Berkarda S

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:(68)Ga-Dotatoc has become the PET radiopharmaceutical of choice for the diagnosis and treatment follow-up of neuroendocrine tumours. (68)Ga-Dotatoc is prepared on-site through a so-called magisterial preparation. The use of an appropriate buffer during the radiolabelling step is essential to maximize the lab...

journal_title：Nuclear medicine communications

authors： Bauwens M,Chekol R,Vanbilloen H,Bormans G,Verbruggen A

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the incremental value of technetium-99m-methylene diphosphonate (99mTc-MDP) single-photon emission tomography/computed tomography (SPECT/CT) over planar bone scintigraphy (BS) and SPECT in the diagnosis of avascular necrosis (AVN) of the femoral head. MATERIALS AND METHOD...

journal_title：Nuclear medicine communications

authors： Agarwal KK,Mukherjee A,Sharma P,Bal C,Kumar R

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:A mismatch between thallium-201 ((201)Tl) and iodine-123 ((123)I)-beta-methyl iodophenyl pentadecanoic acid (BMIPP) dual single-photon emission computed tomography (SPECT) reflects a dysfunctional but viable myocardium, such as stunned or hibernating myocardium, in patients with coronary artery disease (CAD)...

journal_title：Nuclear medicine communications

authors： Fujita K,Kasama S,Kurabayashi M

更新日期：2015-02-01 00:00:00

abstract：:Impaired cardiac fatty acid uptake, assessed by the radiolabelled fatty acid analogue beta-methyl-p-iodophenyl pentadecanoic acid (I-123-BMIPP), is observed in the myocardium following acute ischaemic events, but the long-term prognostic implication has not been established. This study aimed to determine the prognosti...

journal_title：Nuclear medicine communications

authors： Nakata T,Kobayashi T,Tamaki N,Kobayashi H,Wakabayashi T,Shimoshige S,Oh-Hori K,Hamabe K,Hirasawa K,Matsuki T,Shogase T,Furudate M,Shimamoto K

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the capability of F-FDG PET/computed tomography (CT)-related metabolic parameters to predict lymph node metastasis (LNM) and occult lymph node metastasis (OLNM) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:Totally 84 patients undergoing curative...

journal_title：Nuclear medicine communications

authors： Xu M,Wang L,Ouyang M,Lin J,Wang L,Zheng X,Miao S,Tang K

更新日期：2019-09-01 00:00:00

abstract：:Our aim was to determine whether the Ca2+ ion or cell membrane Ca2+ and Na+/Ca2+ ion transport systems are involved in maintaining the cell-associated activity of technetium-99m-hexakis-methoxy-isobutyl-isonitrile (99mTc-MIBI) and technetium-99m-ethylene-bis[bis(2-ethoxyethyl)phosphin] (99mTc-tetrofosmin) in tumour ce...

journal_title：Nuclear medicine communications

authors： Arbab AS,Ueki J,Koizumi K,Araki T

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare the sensitivity of single-photon emission computed tomography/computed tomography (SPECT/CT) using 99mTc-sestamibi (MIBI) with that of PET/CT using 11C-methionine (MET) for localization of parathyroid adenomas/hyperplasia in primary hyperparathyroidism. MATERIALS AND ...

journal_title：Nuclear medicine communications

authors： Hayakawa N,Nakamoto Y,Kurihara K,Yasoda A,Kanamoto N,Miura M,Inagaki N,Togashi K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:ECG-gated single photon emission computed tomography (SPECT) myocardial perfusion scintigraphy combined with phase analysis allows for the assessment of left ventricular dyssynchrony. However, there are several software programs available thereby introducing variability in outcome and normal values. The aim ...

journal_title：Nuclear medicine communications

authors： Marques de Souza Filho E,Tinoco Mesquita C,Altenburg Gismondi R,de Amorim Fernandes F,Jan Verberne H

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Medullary thyroid carcinoma is a rare, potentially aggressive tumour, with relatively worse prognosis than well-differentiated thyroid cancer. We evaluated the long-term outcomes and prognosis of medullary thyroid carcinoma patients at a single institution in India and compared outcomes based on results of RE...

journal_title：Nuclear medicine communications

authors： Prabhu M,Shakya S,Ballal S,Ahmed Shamim S,Bal C

更新日期：2020-11-01 00:00:00

abstract：:We studied two different methods for the evaluation of differential renal function in a group of 100 patients with various kidney disorders whose effective renal plasma flow (ERPF) had been calculated previously by single 125I-orthoiodohippurate (OIH) injection and multiple blood sampling. Patients were divided into t...

journal_title：Nuclear medicine communications

authors： Llamas-Elvira JM,Martinez-Paredes M,Jimenez-Heffernan A,Sopena R,Requena MJ,Gonzalez FM,Torres M,Mateo A

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Lymph node metastases are significant prognostic factors in localized non-small-cell lung cancer (NSCLC). Nodal micrometastases may not be detected using current histological methods. AIM:To determine the accuracy and role of sentinel lymph nodes (SLNs) in patients with NSCLC. METHODS:Intraoperative techne...

journal_title：Nuclear medicine communications

authors： Atinkaya C,Ozlem Küçük N,Koparal H,Aras G,Sak SD,Ozdemir N

更新日期：2005-08-01 00:00:00