Circumventing the requirement of binding saturation for receptor quantification using interaction kinetic extrapolation.

abstract：OBJECTIVES:This work aims to assess whether the biochemical response of radium-223-dichloride treatment can be predicted based on the pretherapy bone scan, and consequently if bone scan index (BSI) and maximum lesion intensity have a place as alternatives or as complements to extent of bone disease (EOBD) scoring in pr...

journal_title：Nuclear medicine communications

authors： Roque V,Jessop M,Pereira L,Gape P,Dizdarevic S,Sousa E,Carolino E

更新日期：2019-06-01 00:00:00

abstract：:The technique of 99Tcm-labelled red cell scintigraphy as a means of detecting rebleeding was investigated in 33 patients with bleeding peptic ulcers. Scintigrams were performed twice during the 24 h period succeeding diagnostic endoscopy. There was scintigraphic evidence of rebleeding in 23 patients but this was clini...

journal_title：Nuclear medicine communications

authors： Kinnear WJ,Dickinson RJ,Buxton-Thomas M,Wraight EP

更新日期：1985-09-01 00:00:00

abstract：:In 70 patients with angiographically confirmed coronary heart disease and in 10 controls, a 4 h exercise (E) (injection of 150 MBq 99Tcm-MIBI) rest (R) (800 MBq) protocol was employed. Of these, 10 patients with 21 myocardial defects after E received a third injection 24 h after. SPECT was used to image myocardial dis...

journal_title：Nuclear medicine communications

authors： Buell U,Dupont F,Uebis R,Kaiser HJ,Kleinhans E,Reske SN,Hanrath P

更新日期：1990-02-01 00:00:00

abstract：:Cerebral blood flow (CBF) can be quantified non-invasively using the brain perfusion index (BPI) determined from radionuclide angiographic data generated with 99mTc-hexamethylpropylene amine oxime (99mTc-HMPAO). When measuring the BPI, manual drawing of regions of interest (ROIs) (manual ROI method) for the extraction...

journal_title：Nuclear medicine communications

authors： Murase K,Nagayoshi M,Uenishi Y,Kawamata M,Yamazaki Y,Takasawa M,Oku N,Hatazawa J

更新日期：2004-03-01 00:00:00

abstract：:Good working practice and legal obligation impose a duty on nuclear medicine departments to check syringe activities before administration to a patient. If syringe guards are used to reduce staff exposure while drawing up injections, the guard has to be removed to measure the activity in a conventional reentrant ioniz...

journal_title：Nuclear medicine communications

authors： Hastings DL,Hillel PG,Jeans SP,Waller ML

更新日期：1997-08-01 00:00:00

abstract：:Mammography is the screening test of choice for breast cancer. Its low specificity leads to a large number of unnecessary biopsies. Scintimammography, with either Tc-sestamibi (MIBI) or Tc-anti-carcinoembryonic antigen (CEA) Fab', has been proposed as a non-invasive test to lower the high false positive rate of mammog...

journal_title：Nuclear medicine communications

authors： Sanidas EE,Koukouraki S,Velidaki A,Manios A,Stathopoulos E,De Bree E,Kafousi M,Kodogiannis E,Karkavitsas N,Tsiftsis DD

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To determine whether any patient or hepatic tumor characteristics are predictive of hepatopulmonary shunt fraction when performed before radioembolization. MATERIALS AND METHODS:A retrospective review was performed on 190 patients who underwent preradioembolization hepatic arteriography with calculation of h...

journal_title：Nuclear medicine communications

authors： Yerubandi V,Ronald J,Howard BA,Suhocki PV,James OG,Wong TZ,Kim CY

更新日期：2016-09-01 00:00:00

abstract：:Since 99Tcm-DTPA is diffusible and not significantly protein bound in plasma, it rapidly enters the extravascular space following injection. Therefore, during the first few minutes of the DTPA renogram, the period on which the measurements of individual kidney glomerular filtration rate and differential function are b...

journal_title：Nuclear medicine communications

authors： Peters AM,George P,Ballardie F,Gordon I,Todd-Pokropek A

更新日期：1988-12-01 00:00:00

abstract：:A postal survey of UK nuclear medicine departments was undertaken to collate information on equipment, numbers of procedures and staffing levels for the years 1992 and 1993. It was estimated that there are 235 sites undertaking nuclear medicine, the total number of procedures performed being some 490,000 in 1993 compa...

journal_title：Nuclear medicine communications

authors： Elliott AT,Elliott FM,Shields RA

更新日期：1996-01-01 00:00:00

abstract：:Technetium-99m-sestamibi (99mTc-MIBI) imaging is a well-established modality in oncologic investigations. The current study aimed to investigate whether any relationship could be found between 99mTc-MIBI uptake and local perfusion in malignant bone and soft-tissue tumours. It also aimed to compare 99mTc-MIBI images wi...

journal_title：Nuclear medicine communications

authors： Ozcan Z,Burak Z,Erinç R,Dirlik A,Başdemir G,Sabah D,Ozkiliç H

更新日期：2001-06-01 00:00:00

abstract：:The physical considerations of using dual isotope brain SPECT imaging to monitor blood flow changes during cognitive activation studies were investigated. These factors included field uniformity, spatial resolution and crosstalk. Serial dual isotope single photon emission computed tomographic (SPECT) studies of a test...

journal_title：Nuclear medicine communications

authors： Madsen MT,O'Leary DS,Andreasen NC,Kirchner PT

更新日期：1993-05-01 00:00:00

abstract：:Planar pulmonary scintigraphy is still regularly performed for the evaluation of pulmonary embolism (PE). However, only about 50-80% of cases can be resolved by this approach. This study evaluates the ability of tomographic acquisition (single photon emission computed tomography, SPECT) of the perfusion scan to improv...

journal_title：Nuclear medicine communications

authors： Collart JP,Roelants V,Vanpee D,Lacrosse M,Trigaux JP,Delaunois L,Gillet JB,De Coster P,Vander Borght T

更新日期：2002-11-01 00:00:00

abstract：:Should one correct for extrathyroidal neck radioactivity ('neck background') when interpreting perchlorate discharge test results? A new background correction method was developed using a linear probe. 123I produces photon peaks at two energy levels: 159 keV (gamma-rays) and 28 keV (X-rays), with an attenuation of 15 ...

journal_title：Nuclear medicine communications

authors： Arntzenius AB,van der Heide D,Meinders AE

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....

journal_title：Nuclear medicine communications

authors： Lin WY,Tsai SC,Hung GU

更新日期：2005-04-01 00:00:00

abstract：:Split and total renal function are commonly assessed from time-activity curves obtained from gamma camera renography with 99Tcm-diethylenetriamine pentaacetate (99Tcm-DTPA) and 99Tcm-mercaptoacetyl-triglycine (99Tcm-MAG3). The impact of the statistical noise associated with these curves on the total precision in split...

journal_title：Nuclear medicine communications

authors： Moonen M,Jacobsson L

更新日期：1997-04-01 00:00:00

abstract：:Fluorine-18-sodium fluoride (F-NaF) PET/CT is a relatively new and high-resolution bone imaging modality. Since the use of F-NaF PET/CT has been increasing, it is important to accurately assess the images and be aware of normal distribution and major artifacts. In this pictorial review article, we will describe the no...

journal_title：Nuclear medicine communications

authors： Sarikaya I,Elgazzar AH,Sarikaya A,Alfeeli M

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the degree and location of the reparative process in early osteonecrosis of the femoral head on the basis of single-photon emission computed tomography/computed tomography (SPECT/CT) with technetium-99m hydroxymethylene diphosphonate. MATERIALS AND METHODS:This study was ap...

journal_title：Nuclear medicine communications

authors： Motomura G,Yamamoto T,Abe K,Nakashima Y,Ohishi M,Hamai S,Doi T,Honda H,Iwamoto Y

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of (99m)Tc-pamidronate ((99m)Tc-APD) against (99m)Tc-medronate ((99m)Tc-MDP) as a new bone-seeking agent using intact bone and fractured femur in a rat model. METHODS:(99m)Tc-APD was prepared by the stannous reduction method. Scintigraphic images were obtained at 2 h and 24 h after ...

journal_title：Nuclear medicine communications

authors： Kumar V,Kumar D,Howman-Giles RB,Little DG

更新日期：2007-02-01 00:00:00

abstract：:The aim of the study was to measure the actual dose at 1 m from the patients per unit activity with the aim of providing a more accurate prediction of the dose levels around radioiodine patients in the hospital, as well as to compare our results with the literature. In this work the demonstration of a patient body tis...

journal_title：Nuclear medicine communications

authors： Soliman K,Alenezi A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Radium-223 was a treatment approved for patients with metastatic castrate-resistant prostate cancer, symptomatic bone metastases and no-visceral metastases, in progression after at least two prior lines of systemic therapy, or ineligible for any available systemic treatment. The aim of this study was to prov...

journal_title：Nuclear medicine communications

authors： Gazzilli M,Durmo R,Cossalter E,Cerudelli E,Panarotto MB,Albano D,Bertagna F,Giubbini R

更新日期：2020-04-01 00:00:00

abstract：:Patients with acute arterial occlusion may suffer from significant muscle necrosis. It is important to determine the amount of regional muscle necrosis for prognostic purposes and evaluation of therapy. We have used technetium-99m-pyrophosphate (PPi) with single photon emission computed tomography (SPECT) to quantitat...

journal_title：Nuclear medicine communications

authors： Yip TC,Houle S,Hayes G,Forrest I,Nelson L,Walker PM

更新日期：1990-02-01 00:00:00

abstract：:The aim of this study was to develop a quantitative method to assess viable tumour based on post-operative 201Tl single photon emission tomography (SPET). We studied 15 patients with histologically defined highly malignant gliomas in the post-operative phase before initiation of adjuvant treatment. A 201Tl index was c...

journal_title：Nuclear medicine communications

authors： Källén K,Geijer B,Andersson AM,Holtås S,Ryding E,Rosén I

更新日期：1999-09-01 00:00:00

abstract：:Medullary thyroid cancer (MTC) arises from parafollicular C cells and is an elusive tumor to image. It occurs as a sporadic neoplasm in 70-80% of cases and is hereditary in 20-30% because of germline mutations of the rearranged during transfection proto-oncogene. Successful disease management relies on accurate stagin...

journal_title：Nuclear medicine communications

authors： Wong KK,Laird AM,Moubayed A,Chondrogiannis S,Marzola MC,Evangelista L,Gross MD,Rubello D

更新日期：2012-07-01 00:00:00

abstract：:Left ventricular ejection fractions (EF) were measured with a nuclear stethoscope (NSt, beat-to-beat and ECG gated summation method) and contrast ventriculography (VG) immediately following one another (IFOA) (r X 0.96 and 0.95, respectively, n = 13). NSt and ECG gated gamma camera (MUGA) recordings IFOA were compared...

journal_title：Nuclear medicine communications

authors： Lund O,Rasmussen K,Jensen FT,Hansen HH

更新日期：1986-05-01 00:00:00

abstract：:The advent of PET instrumentation signaled the beginning of a new perspective in nuclear medicine diagnostic imaging. PET systems rely on several corrections that must be applied in order to establish accurate and reliable quantification. The inherent properties of PET detector architecture and the crystals themselves...

journal_title：Nuclear medicine communications

authors： Theodorakis L,Loudos G,Prassopoulos V,Kappas C,Tsougos I,Georgoulias P

更新日期：2013-11-01 00:00:00

abstract：:The aim of this study was to describe and evaluate an approach for improving radiopharmaceutical supply chain safety by implementing bar code technology. We first evaluated the current situation of our radiopharmaceutical supply chain and, by means of the ALARM protocol, analysed two dispensing errors that occurred in...

journal_title：Nuclear medicine communications

authors： Matanza D,Hallouard F,Rioufol C,Fessi H,Fraysse M

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES AND METHODS:The recommended method for the measurement of radiochemical purity (RCP) of ¹¹¹In-labelled pentetreotide is thin-layer chromatography with a silica gel as the stationary phase and a 0.1 N sodium citrate solution (pH 5) as the mobile phase. According to the supplier's instructions, the mobile phas...

journal_title：Nuclear medicine communications

authors： Salgado-Garcia C,Montoza-Aguado M,Luna-Alcaide AB,Segovia-Gonzalez MM,de Mora ES,Lopez-Martin J,Ramos-Font C,Jimenez-Heffernan A

更新日期：2011-12-01 00:00:00

abstract：AIM:The aim of this study was to investigate the value of cystatin C and beta-trace protein (BTP) levels in determination of the glomerular filtration rate (GFR) by accepting the technetium-99m diethylenetriamine pentaacetic acid (Tc-DTPA) method as the gold standard for GFR measurement in renal transplant patients wit...

journal_title：Nuclear medicine communications

authors： Oner AO,Aydin F,Demirelli S,Budak ES,Davran F,Akbas H,Kocak H,Suleymanlar G,Gungor F

更新日期：2014-07-01 00:00:00

abstract：AIM AND PURPOSE:Radionuclide imaging of the kidneys using dimercaptosuccinic acid chelate labeled with technetium-99m (Tc-DMSA) is a well-established method for evaluating the extent of kidney parenchymal involvement in the scenario of urinary tract infection and for the estimation of the functional renal mass. We have...

journal_title：Nuclear medicine communications

authors： Gorenberg M,Radan L,Kosakov R,Amirav I

更新日期：2010-07-01 00:00:00

abstract：:The efficacy of wipe tests for assessing 99Tcm surface contamination was measured. Four types of surface were contaminated with four radiopharmaceuticals and wiped using four types of swab. The fraction of activity removed was measured by direct monitoring for each combination of surface, pharmaceutical and swab. The ...

journal_title：Nuclear medicine communications

authors： Scott LE,Gibson CJ

更新日期：1991-02-01 00:00:00