201Tl scintigraphy in the staging of lung cancer, breast cancer and lymphoma.

Abstract:

:To evaluate 201Tl in the detection of the primary tumour, lymph node involvement and mediastinal spread we have studied a total of 188 patients with histologically proven lung cancer, breast cancer or malignant lymphoma. Ten patients with benign lung disease were also examined. Static images were performed 20 min after intravenous injection of 75 MBq of thallous (201Tl) chloride. The results were compared with those of standard staging procedures including CT scanning and mediastinal exploration. Thallium-201 imaging was highly sensitive in detecting the primary tumour (lung cancer 86%, breast carcinoma 100%, lymphoma 85%), but showed low sensitivity in detecting mediastinal spread or lymph node involvement. Thallium-201 uptake was also observed in active sarcoidosis (one case) and active TB (two cases). We conclude that 201Tl imaging is unlikely to have a clinically useful role in the diagnosis or staging of lung cancer, breast cancer or lymphoma.

journal_name

Nucl Med Commun

authors

Sehweil AM,McKillop JH,Milroy R,Sayed MA,Ziada G,Banham SW,Davidson KG,Ragib A,Omar YT,Abdel-Dayem HM

doi

10.1097/00006231-199004000-00002

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

263-9

issue

4

eissn

0143-3636

issn

1473-5628

journal_volume

11

pub_type

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