Abstract:
:A bleeding child is a cause of great concern and often, panic, for parents and pediatricians alike. Causes of bleeding could be trivial or secondary to an underlying bleeding disorder or a potentially serious systemic illness. Based on etiology, they can be categorized into disorders affecting platelets or the coagulation cascade and can be inherited or acquired. A systematic approach with relevant clinical history and examination along with appropriate laboratory investigations aid in reaching the diagnosis promptly. Indication and administration of blood products including fresh frozen plasma, cryoprecipitate, random donor and single donor apheresis platelets is elaborated. Management of hemophilia, Von Willebrand disease, disseminated intravascular coagulation and bleeding in cyanotic congenital heart disease, among other causes is outlined. Role of antifibrinolytic therapy, desmopressin and recombinant factor VIIa is briefly described. The review outlines the approach to a bleeding child in the emergency room. Practical points in history, examination, investigations and management are discussed. Management in resource constraint setting of developing countries is addressed.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Bansal D,Oberoi S,Marwaha RK,Singhi SCdoi
10.1007/s12098-012-0918-2subject
Has Abstractpub_date
2013-05-01 00:00:00pages
411-20issue
5eissn
0019-5456issn
0973-7693journal_volume
80pub_type
杂志文章,评审abstract:OBJECTIVE:To evaluate the effect of folic acid supplementation on seizure control in folate deficient children receiving long term antiepileptic therapy. METHODS:In a prospective interventional study, 140 children between age group 6 mo to 180 mo fulfilling the inclusion criteria were enrolled in study group, from Oct...
journal_title:Indian journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/s12098-018-2608-1
更新日期:2018-07-01 00:00:00
abstract::Staff of the neonatal intensive care unit (NICU) at the L.T.M.G. Hospital in Bombay, India exclusively feeds all infants breast milk. A lactation management nurse oversees its formal milk banking system by encouraging health mothers of NICU infants to donate milk and by assessing daily milk demand. Breast milk dono...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02727917
更新日期:1990-05-01 00:00:00
abstract::Locked-in syndrome is characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral horizontal gaze palsy and anarthria, with preserved consciousness. It is due to a ventral pontine lesion following a basilar artery occlusion. We report the first Indian case report of locked-in syndrom...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0200-4
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:To investigate factors involved in causing hypocalcemia in critically ill patients. METHODS:The patients aged 1 mo to 18 y, admitted to PICU at Nemazee Hospital, from May through November 2012, were reviewed. Those with impaired calcium hemostasis or on vitamin-D supplement were excluded. Calcitonin and par...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1536-y
更新日期:2015-03-01 00:00:00
abstract::Superior mediastinal syndrome (SMS) is an uncommon manifestation of malignant neoplastic disease in children. The commonest neoplastic cause of SMS is Non Hodgkin lymphoma. Acute myeloid leukemia (AML) as a cause of SMS is extremely uncommon in childhood. The authors hereby report a case of a child with AML who presen...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0799-4
更新日期:2013-02-01 00:00:00
abstract::Intrauterine growth retardation (IUGR) is an important determinant of neonatal mortality, morbidity and poor neurologic outcome. The study was aimed to evaluate the magnitude of perinatal risk factors in causation and the neonatal outcome of small for gestational age (SGA) babies. One hundred and three SGA babies born...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02752452
更新日期:1997-03-01 00:00:00
abstract::Cerebral palsy is a common neurodevelopmental condition encountered by pediatricians. The condition may present itself in many different clinical spectra. The etiological and risk factors are many and an awareness of the interplay of multiple factors in the causation of CP is crucial. In many cases, the cause of Cereb...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02731117
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To find out various life stressors of adolescents, coping strategies adopted by them and the impact of stress on adolescent mental health. METHODS:A descriptive, cross sectional study was conducted in the schools in south zone of Delhi, capital city of the country. Data was collected on 360 adolescents betwe...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-015-1710-x
更新日期:2015-09-01 00:00:00
abstract::Severely malnourished children (26), weight for age 55.27 +/- 3.17, were identified in a colony of predominantly Muslim urban slum dwellers of low economic status. An equal number of normally nourished children matched for age, sex and per capita income were identified. A strong relation was found between nutritional ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751136
更新日期:1991-03-01 00:00:00
abstract::The packing and composition of ORS has undergone a change since its introduction. In India, some companies are manufacturing smaller pouches (4.2 g) to be dissolved in 200 ml of water. Therefore, out of confusion some prescribers routinely advise the patients to dissolve the standard formulation ORS pouch (21 g) in a ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0095-0
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To analyze non benign neonatal arrhythmias (NA) observed in a tertiary neonatal intensive care unit (NICU). METHODS:From June 2006 through July 2011, newborns admitted to the NICU for NA or diagnosed as NA after hospitalization were evaluated retrospectively. The newborns with non benign NA were included in ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0852-3
更新日期:2013-07-01 00:00:00
abstract::Gastro-esophageal reflux (GER) is a common occurrence in newborns and a cause of anxiety to most parents. This physiological process needs to be closely differentiated from pathological reflux. The clinical signs in infants are generally non-specific which makes the distinction difficult. The diagnostic options in inf...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-014-1535-z
更新日期:2015-01-01 00:00:00
abstract::Hepatitis B has attracted a lot of attention in recent times. It has been suggested that it is a widely prevalent disease and an important cause of morbidity and mortality in our country. A dispassionate analysis of available data suggests that the prevalence of disease may be much less than believed hitherto, and the...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723142
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:Heterosexual contact is the predominant mode of transmission among adults in India with an increasing number of women of childbearing age becoming infected with HIV. Consequently, children in India increasingly getting infected, primarily from vertical transmission. A retrospective review of the profile of HI...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02724249
更新日期:2003-08-01 00:00:00
abstract::Undescended testis or cryptorchidism is a common problem encountered in children. Despite the abundant literature on the pathology and management of undescended testis, it is the subject of numerous misgivings and controversies. The article reviews available literature on the entity and their relevance in clinical pra...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02829826
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:To identify biomarkers for neuronal injury and outcome in perinatal asphyxia. METHODS:This prospective cohort study was done in authors' level III NICU involving 80 neonates - 40 babies with perinatal asphyxia and 40 weight and gender matched normal neonates. Levels of cytokines IL-6, IL -1β, IL-2 and TNF -...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1575-4
更新日期:2015-05-01 00:00:00
abstract::Neurological findings in HIV are common and include cognitive impairment, microcephaly, nonspecific white matter lesions and seizures. Cerebral vasculopathy and stroke are uncommon and may be due to primary HIV vasculopathy or opportunistic infections such as tuberculosis and cryptococcal meningitis. The authors descr...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-016-2073-7
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:To establish a technique for mutation identification and prenatal screening in confirmed cases of Canavan disease. METHOD:Mutations in ASPA gene were identified by sequencing. Six exons of ASPA gene were amplified using intronic primers flanking the exons and then sequenced on ABI 3500Dx automated unit. Thi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0862-1
更新日期:2013-01-01 00:00:00
abstract::The primary goal in the management of a child with urinary tract infection (UTI) is to prevent recurrence of UTI and acquired renal damage. Approximately 15% of children develop renal scarring after a first episode of febrile UTI. Vesico-ureteric reflux (VUR) is diagnosed in 30-40% of children imaged after first febri...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-017-2359-4
更新日期:2017-07-01 00:00:00
abstract:: ...
journal_title:Indian journal of pediatrics
pub_type: 信件
doi:10.1007/s12098-018-2719-8
更新日期:2019-01-01 00:00:00
abstract::The Polymerase Chain Reaction (PCR) is a revolutionary new means of amplifying, i.e., replicating, selected DNA sequences in vitro. This procedure is highly sensitive and rapid, requiring few hours for detection of amplified target DNA whereas it often takes several weeks for the identification of many fastidious orga...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02737744
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To review contemporary guidelines and therapies for pediatric cardiac arrest and discuss potential novel therapies. METHODS:Key articles and guidelines in the field were reviewed along with recent publications in the fields of neurointensive care and neuroscience germane to cerebral resuscitation. RESULTS:A...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-008-0117-3
更新日期:2008-06-01 00:00:00
abstract::The clinical presentation of pseudohypoaldosteronism (PHA) mimics congenital adrenal hyperplasia (CAH). Poor response of the dehydration and electrolyte abnormalities to steroid therapy should make one suspect PHA. The treatment is supportive in the form of salt replacement and sodium resonium. We report a case of PHA...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02758269
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the post treatment changes in disease activity and inflammatory markers over time in longitudinal follow-up involving different subtypes of juvenile idiopathic arthritis (JIA) patients. METHODS:This prospective longitudinal study, carried out over a period of 2 y, included JIA patients, both old ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2292-6
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To compare cultures throat swab after physiotherapy with results of sputum culture in identification of lower airway pathogens in children with cystic fibrosis. METHODS:387 samples of sputum cough swabs, throat swab and throat swab after physiotherapy were collected from 48 patients of cystic fibrosis and cu...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02725650
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:The long QT syndrome (LQTS) is a disorder of the electrical system of the heart, due to dysfunction of the ion channels and involving the repolarisation process. The inherited form occurs when there is a mutation in one of the genes which encode the making of a channel. Prolongation of the QT interval renders...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02859375
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:To describe the needs of relatives of children admitted to an Intensive Care Unit and compare their needs with the perspectives of doctors, nurses and administrators. METHODS:This is a descriptive comparative study done at a tertiary care PICU from South India. A modified Critical Care Family Needs Inventory...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2324-2
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:Hirschsprung's disease may be associated with a number of congenital anomalies of which Down's syndrome and intestinal atresias are commonly encountered. The study aimed to assess the impact of rare associated anomalies on the diagnosis and management of Hirschsprung's disease. METHODS:A retrospective review...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02762106
更新日期:2001-09-01 00:00:00
abstract::A pair of female thoraco-omphalopagus twins, with two pairs of lungs, common diaphragm and separate pleural cavities was separated at the age of 5(1/2) months after a parasitic relationship had developed between them. Before separation both the babies developed recurrent respiratory tract infection and frequent diarrh...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02730669
更新日期:2004-08-01 00:00:00
abstract::Death is a natural process, but the definition of death varies depending on the cultural and religious background, all over the world. The historical development of the concept and the current criteria in the determination of brain death must be well understood. Termination of life support measures in a brain dead chi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02730887
更新日期:1998-07-01 00:00:00