Can throat swab after physiotherapy replace sputum for identification of microbial pathogens in children with cystic fibrosis?

Abstract:

OBJECTIVE:To compare cultures throat swab after physiotherapy with results of sputum culture in identification of lower airway pathogens in children with cystic fibrosis. METHODS:387 samples of sputum cough swabs, throat swab and throat swab after physiotherapy were collected from 48 patients of cystic fibrosis and cultured for aerobic bacteria. The results of cultures of cough swabs, throat swab and throat swab after physiotherapy were compared with results of sputum culture. RESULTS:There was good concordance between culture results of sputum and other methods. Over all concordance was 70%, 81% and 92% with cough swab, throat swab and throat swab after physiotherapy. Sensitivity for isolation of Pseudomonas aeruginosa by throat swab, cough swab and throat swab after physiotherapy was 40%, 42% and 82% respectively. Specificity for isolation of Pseudomonas by throat swab, cough swab and throat swab after physiotherapy was 99%, 100% and 99% respectively. Sensitivity for isolation of Staphylococcus aureus by throat swab, cough swab and throat swab after physiotherapy was 57%, 50% and 100% respectively. Specificity for isolation of Staphylococcus by throat swab, cough swab and throat swab after physiotherapy was 99% for all these methods. CONCLUSION:It is concluded that throat swab after physiotherapy in a child with CF can be used reliably for identification of lower airway pathogens.

journal_name

Indian J Pediatr

authors

Kabra SK,Alok A,Kapil A,Aggarwal G,Kabra M,Lodha R,Pandey RM,Sridevi K,Mathews J

doi

10.1007/BF02725650

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

21-3

issue

1

eissn

0019-5456

issn

0973-7693

journal_volume

71

pub_type

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