Congenital hypothyroidism and the importance of universal newborn screening.

Abstract:

:Congenital hypothyroidism (CH) is one of the most common preventable causes of mental retardation in children. Early diagnosis and treatment prevent the devastating outcome of mental retardation. Clinical features of CH are subtle and are not evident early in the neonatal period. Therefore, universal newborn screening (NS) is effective in detecting CH and implementing early treatment. This article reviews the current literature regarding the epidemiology, etiology, classification, clinical features, diagnosis of primary CH, and the management of abnormal newborn screen as well as treatment and prognosis of primary CH and outlines the importance of universal newborn screening in preventing mental retardation.

journal_name

Indian J Pediatr

authors

Salim FA,Varma SK

doi

10.1007/s12098-013-1299-x

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

53-7

issue

1

eissn

0019-5456

issn

0973-7693

journal_volume

81

pub_type

杂志文章,评审
  • Clinical profile and management of PDA in neonates.

    abstract::Patent ductus arteriosus (PDA) is recognised more often with increasing survival of preterm babies. The pharmacological closure of ductus by indomethacin has changed the management of PDA. Twenty neonates admitted over a period of 21 months to Neonatal Intensive Care Unit (NICU) of M.S. Ramaiah Medical College hospita...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02726122

    authors: Shanthala CC,Maiya PP,Vishwanath D,Banakappa N,Swamy PM,Desai N,Ravikishore,Srinivas KH

    更新日期:1997-09-01 00:00:00

  • Concepts, Utility and Limitations of Cord Blood Banking: What Clinicians Need to Know.

    abstract::Stem cell transplantation and cord blood banking have received much popularity among general public and medical professionals in the recent past. But information about the scientific aspects, its utility and limitations is incomplete amongst laypersons as well as many medical practitioners. Stem cells differ from all ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-018-2651-y

    authors: Narayanan DL,Phadke SR

    更新日期:2019-01-01 00:00:00

  • Molecular diagnosis of infectious diseases.

    abstract::The Polymerase Chain Reaction (PCR) is a revolutionary new means of amplifying, i.e., replicating, selected DNA sequences in vitro. This procedure is highly sensitive and rapid, requiring few hours for detection of amplified target DNA whereas it often takes several weeks for the identification of many fastidious orga...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02737744

    authors: Raj P

    更新日期:1997-07-01 00:00:00

  • Esophageal Button Battery in the Pediatric Population: Experience from a Tertiary Care Center.

    abstract:OBJECTIVES:To highlight different patterns of clinical presentation, share authors' experience in the management of children following button battery ingestion and their outcomes. METHODS:This is a single center descriptive cohort study with a total duration of 5 y (January 2014 through December 2018). Battery removal...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-020-03222-1

    authors: Anand S,Jain V,Agarwala S,Dhua AK,Yadav DK

    更新日期:2020-08-01 00:00:00

  • Isolated post-traumatic right-sided diaphragmatic hernia.

    abstract::A 3-yr-old boy presented with respiratory distress of 2 days duration. There was a history of blunt trauma to the lower chest having occurred 5 days earlier. Although missed initially, serial chest X-rays and a computed tomographic (CT) scan revealed an isolated traumatic right-sided diaphragmatic hernia without any i...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0282-z

    authors: Jain P,Kushwaha AS,Pant N,Debnath PR,Chadha R,Choudhury SR,Kumar P

    更新日期:2009-11-01 00:00:00

  • Surgical therapy for the univentricular heart.

    abstract::The natural history of the univentricular physiology is determined primarily by the presence (severity) or absence of obstruction to pulmonary blood flow and secondarily by the single ventricular cardiomyopathy that develops in response to chronic volume overload. Important obstruction to pulmonary blood flow will aff...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02760487

    authors: Sharma R

    更新日期:2000-07-01 00:00:00

  • Duchenne muscular dystrophy: prevalence and patterns of cardiac involvement.

    abstract:UNLABELLED:In about 10% cases of Duchenne muscular dystrophy (DMD), death is due to cardiac dysfunction. The recognition of cardiomyopathy in DMD is thus important. OBJECTIVE:To assess cardiac involvement in DMD patients by clinical, radiographic, electrocardiographic (ECG) and echocardiographic monitoring and correla...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02731732

    authors: Gulati S,Saxena A,Kumar V,Kalra V

    更新日期:2005-05-01 00:00:00

  • Vertically transmitted HIV infection having first clinical manifestations at 13 y of age.

    abstract::Untreated vertically transmitted human immunodeficiency virus (HIV) infection progresses rapidly with 50% mortality at 1 y and most of the remainder dying before 5 y of age. The authors present a case of a 13-y-old boy, a paternal orphan with vertically transmitted HIV infection, lost to follow up after diagnosis in i...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-011-0670-z

    authors: Sagar A,Vasudevan B

    更新日期:2012-09-01 00:00:00

  • Multiple Intracranial Aneurysms in HIV Infection.

    abstract::Neurological findings in HIV are common and include cognitive impairment, microcephaly, nonspecific white matter lesions and seizures. Cerebral vasculopathy and stroke are uncommon and may be due to primary HIV vasculopathy or opportunistic infections such as tuberculosis and cryptococcal meningitis. The authors descr...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-016-2073-7

    authors: Dhawan SR,Gupta A,Gupta V,Singhi PD

    更新日期:2016-08-01 00:00:00

  • Innovative programmes of medical education: II. Commentary and lessons for India.

    abstract::Major areas in which innovative approaches in medical education have been tried include student selection, learning strategies, and community orientation. It is relatively easier to implement innovations in a new institution. In established medical schools, running two simultaneous curricula tracks, the traditional an...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02751045

    authors: Paul VK

    更新日期:1993-11-01 00:00:00

  • IgM nephropathy in India: a single centre experience.

    abstract:OBJECTIVE:To find out the incidence and natural history of IgMN in India. METHODS:Renal biopsies of children ≤12 y age of last 6 y were retrospectively evaluated. Their clinical and biochemical presentation were correlated. Patients with systemic diseases/disorders were excluded from the study. RESULTS:Immunoglobulin...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-012-0693-0

    authors: Vanikar AV,Kanodia KV,Patel RD,Suthar KS,Patel HV,Gumber MR,Trivedi HL

    更新日期:2012-08-01 00:00:00

  • Neonatal nosocomial infections in Bahrami Children Hospital.

    abstract:OBJECTIVE:Nosocomial infections are one of the most important causes of mortality and morbidity in hospitals. These are major public health problems worldwide, but particularly in developing countries. These infections have the most common frequency in pediatric hospitals-especially in neonatal wards- second to burn ho...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02825479

    authors: Salamati P,Rahbarimanesh AA,Yunesian M,Naseri M

    更新日期:2006-03-01 00:00:00

  • Predictors of CPAP Failure - 10 years' Data of Multiple Trials from a Single Center: A Retrospective Observational Study.

    abstract:OBJECTIVES:To identify risk factors and outcomes associated with early failure of nasal continuous positive airway pressure (CPAP) in premature infants with respiratory distress (RD). METHODS:This is a retrospective observational study of all the preterm infants with RD primarily supported on nasal CPAP and included i...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-020-03399-5

    authors: Murki S,Kandraju H,Oleti T,Saikiran,Gaddam P

    更新日期:2020-11-01 00:00:00

  • Current and future therapies of pediatric cardiopulmonary arrest.

    abstract:OBJECTIVE:To review contemporary guidelines and therapies for pediatric cardiac arrest and discuss potential novel therapies. METHODS:Key articles and guidelines in the field were reviewed along with recent publications in the fields of neurointensive care and neuroscience germane to cerebral resuscitation. RESULTS:A...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-008-0117-3

    authors: Manole MD,Hickey RW,Clark RS,Kochanek PM

    更新日期:2008-06-01 00:00:00

  • Essential fatty acids, DHA and human brain.

    abstract::Essential fatty acids cannot be synthesized in the body but they are required for maintenance of optimal health. There are two classes of polyunsaturated fatty acids (PUFAs)--omega-6 and omega-3. The parent omega-6 fatty acid, linoleic acid (LA) is desaturated in the body to form arachidonic acid while parent omega-3 ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Singh M

    更新日期:2005-03-01 00:00:00

  • Pulse polio immunization in district Panipat: a process evaluation.

    abstract:OBJECTIVE:To evaluate all steps of pulse polio immunization on special sub national immunization day. METHODS:On a sub-national immunization day (SNID), 120 booths were randomly selected from 662 booths by probability proportionate to size (PPS) sampling technique. RESULTS:It was observed that attendance in the distr...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0025-1

    authors: Goel NK,Pathak R,Galhotra A,Dankal C,Swami HM

    更新日期:2009-01-01 00:00:00

  • Lipoprotein Lipase Deficiency.

    abstract:OBJECTIVES:To analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective indigenous diet for management of this disorder. METHODS:This is a single-centre retrospective study. Fifteen patients from 14 kindreds with severe hypertriglyceridemia (more...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-020-03305-z

    authors: Kuthiroly S,Yesodharan D,Radhakrishnan N,Ganapathy A,Mannan AU,Hoffmann MM,Nampoothiri S

    更新日期:2021-02-01 00:00:00

  • Early neonatal streptococcal infection.

    abstract:OBJECTIVE:To determine the incidence of early onset Group B Streptococcal (GBS) infection in infants born over a two year period and to determine the outcome of sepsis evaluation in infants born to mothers with GBS colonization. METHODS:The charts of infants born to mothers with GBS colonization were reviewed for deta...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02759920

    authors: Niduvaje K,Amutha C,Roy J

    更新日期:2006-07-01 00:00:00

  • Correlation of hypocalcemia with serum parathyroid hormone and calcitonin levels in pediatric intensive care unit.

    abstract:OBJECTIVES:To investigate factors involved in causing hypocalcemia in critically ill patients. METHODS:The patients aged 1 mo to 18 y, admitted to PICU at Nemazee Hospital, from May through November 2012, were reviewed. Those with impaired calcium hemostasis or on vitamin-D supplement were excluded. Calcitonin and par...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-014-1536-y

    authors: Haghbin S,Serati Z,Sheibani N,Haghbin H,Karamifar H

    更新日期:2015-03-01 00:00:00

  • Are our donors safe?

    abstract::Blood is defined as a 'drug' under the Drugs and Cosmetics Act. The Standard of drugs is laid down in the Indian Pharmacopoeia. The first step towards blood safety is to encourage blood donations, which are voluntary, non-remunerated and obtained from low-risk and regular donors. A regular donor is one who donates blo...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02728866

    authors: Viswanathan C

    更新日期:2001-01-01 00:00:00

  • The importance of pulmonary function tests in adenotonsillectomy indications.

    abstract::Children who had undergone adenotonsillectomy for recurrent adenotonsillitis showing no signs of clinical or radiological obstructive manifestations were evaluated with pulmonary function tests before, and one month after the operation. In relation to the result obtained by function tests, 60% of 45 cases (27) had the...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02822185

    authors: Kavukcu S,Coskun S,Cevik N,Kuscu B,Akkoclu A

    更新日期:1993-03-01 00:00:00

  • Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy.

    abstract::Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral P...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0190-2

    authors: Engiz O,Berberoglu M,Siklar Z,Bilir P,Ocal G

    更新日期:2009-09-01 00:00:00

  • Asymptomatic bacteriuria in school children.

    abstract::We studied 2447 asymptomatic school children by microscopic examination of urine and culture of a clear voided midstream specimen of urine. Only three children had bacteriuria (0.12%). Urographic abnormalities were detected in both the cases, which could be investigated. This study has shown that asymptomatic bacteriu...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02749724

    authors: Joseph TP,Sreekumaran MI

    更新日期:1989-01-01 00:00:00

  • The Journey of Newborn Screening: Inception to Conclusion.

    abstract:: ...

    journal_title:Indian journal of pediatrics

    pub_type: 社论

    doi:10.1007/s12098-017-2544-5

    authors: ICMR Task Force on Inherited Metabolic Disorders.

    更新日期:2018-11-01 00:00:00

  • Comparison of tympanic and rectal temperature in febrile patients.

    abstract:OBJECTIVE:To compare tympanic membrane temperature and rectal temperature in febrile pediatric patients. METHODS:Sixty febrile children were enrolled as continuous enrollment at initial triage. Two readings of ear temperature were taken in each child with Thermoscan infrared thermometer. Rectal temperature was recorde...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02723215

    authors: Sehgal A,Dubey NK,Jyothi MC,Jain S

    更新日期:2002-04-01 00:00:00

  • Ultrasound Examination of Pediatric Musculoskeletal Diseases and Neonatal Spine.

    abstract::Ultrasound (US) is a simple, non-invasive imaging modality which allows high-resolution imaging of the musculoskeletal (MSK) system. Its increasing popularity in pediatrics is due to the fact that it does not involve radiation, has an ability to visualize non-ossified cartilaginous and vascular structures, allows dyna...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-015-1957-2

    authors: Karnik AS,Karnik A,Joshi A

    更新日期:2016-06-01 00:00:00

  • Safe blood transfusion practices.

    abstract::The advent of AIDS has raised a concern regarding transfusion transmitted diseases. Blood transfusion is safer than ever before through continued improvements in safe donor recruitment, screening of donors, testing of donated blood and appropriate clinical use of blood. The risk of residual infections is further reduc...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02722029

    authors: Bharucha ZS

    更新日期:2001-02-01 00:00:00

  • The Utility of CSF Xpert MTB/RIF in Diagnosis of Tubercular Meningitis in Children.

    abstract:OBJECTIVE:To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y. METHODS:This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from Decem...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-019-03032-0

    authors: A J,Ratageri VH,Illalu S,Fattepur SR,Wari PK

    更新日期:2019-12-01 00:00:00

  • Small for gestational age babies: Indian scene.

    abstract::Intrauterine growth retardation (IUGR) is an important determinant of neonatal mortality, morbidity and poor neurologic outcome. The study was aimed to evaluate the magnitude of perinatal risk factors in causation and the neonatal outcome of small for gestational age (SGA) babies. One hundred and three SGA babies born...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02752452

    authors: Narang A,Chaudhuri MK,Kumar P

    更新日期:1997-03-01 00:00:00

  • Radionuclide scintigraphy in Caroli's disease.

    abstract::Congenital cystic dilatation of the intrahepatic bile ducts involving the major intrahepatic radicles was first described by Caroli and hence named as Caroli's disease. We present here a case in which the only symptom was intermittent pain in the abdomen for last one-and-a-half-year and a radionuclide scan done effect...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02795788

    authors: Sharma R,Mondal A,Taneja V,Rawat HS

    更新日期:1997-01-01 00:00:00