Clinical profile and management of PDA in neonates.

Abstract:

:Patent ductus arteriosus (PDA) is recognised more often with increasing survival of preterm babies. The pharmacological closure of ductus by indomethacin has changed the management of PDA. Twenty neonates admitted over a period of 21 months to Neonatal Intensive Care Unit (NICU) of M.S. Ramaiah Medical College hospital, Bangalore, who were diagnosed to have PDA, were analyzed. The objectives of this retrospective analysis were to study the clinical profile, the efficacy of oral indomethacin and the outcome of PDA. 2-D and Doppler echocardiaography were used to confirm the clinically suspected PDA. These neonates were treated with 3 doses of oral indomethacin (0.2-0.25 mg/kg/dose 12 hourly) along with fluid restriction and oxygen. Echocardiography was repeated to demonstrate the closure of PDA. The incidence of PDA was 2.3% of total NICU admissions. Seventy percent of this cohort were < 32 weeks of gestation, 55% had birth weight of < 1500 gms. Seventy percent (14) neonates had onset of PDA after 48 hrs of life. 81.25% of neonates responded to indomethacin and overall survival rate in treated group was 67%. Drug related complications were noted in 2 newborns. This study illustrates the utility of echocardiography in diagnosing and monitoring PDA in preterm and low birth weight babies with high index of suspicion of this common congenital heart disease. Pharmacological intervention with indomethacin is rewarding with acceptable results.

journal_name

Indian J Pediatr

authors

Shanthala CC,Maiya PP,Vishwanath D,Banakappa N,Swamy PM,Desai N,Ravikishore,Srinivas KH

doi

10.1007/BF02726122

keywords:

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

667-70

issue

5

eissn

0019-5456

issn

0973-7693

journal_volume

64

pub_type

杂志文章
  • Utilizing nasal-tragus length to estimate optimal endotracheal tube depth for neonates in Taiwan.

    abstract:OBJECTIVE:To assess the application of the nasal-tragus length (NTL) to predict the proper endotracheal tube (ETT) depth; also, as relatively thinner size of Asian than Caucasian, the fitness of using the NTL to estimate the optimal ETT depth for neonates in Taiwan was examined. METHODS:The newborn infants who do need...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-010-0278-8

    authors: Wang TC,Kuo LL,Lee CY

    更新日期:2011-03-01 00:00:00

  • Influence of infection on iron profile in severely malnourished children.

    abstract:OBJECTIVE:To study the iron profile and find out an accurate diagnostic tool which reflects iron status in different types of infection in severely malnourished children aged 12 months to 71 months. METHODS:Hundred and Eight (108) children of whom 72 children were infected and 36 non infected severely malnourished chi...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0098-x

    authors: Atiar Rahman M,Mannan MA,Rahman MH

    更新日期:2009-09-01 00:00:00

  • Pediatric Asthma and Food Allergy.

    abstract:OBJECTIVE:To quantitatively summarize the evidence from observational studies on the relation between pediatric asthma and food allergy. METHODS:A literature search was conducted in Medline and EMBASE (August 2016). Two independent reviewers appraised the studies and extracted the estimates of interest. Methodological...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1007/s12098-017-2326-0

    authors: Zhou H,Dai C,Pan J

    更新日期:2017-08-01 00:00:00

  • Importance of patient/parents education in childhood asthma.

    abstract::Asthma is fairly common in pediatric age group and the suffering due to asthma continues to increase despite excellent treatments available. One of the four major components of asthma management is patient education and is critical to the success of asthma management. Reasons for continued suffering include that our m...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,病人教育讲义,评审

    doi:

    authors: Gupta A,Gupta R

    更新日期:2001-09-01 00:00:00

  • Fibroblast growth factor receptor mutations and craniosynostosis: three receptors, five syndromes.

    abstract::The post eighteen months have been exciting time for craniosynostosis research. In a rapid flurry of publications, mutations of fibroblast growth factor receptors (FGFRs) have been identified in three of the best known craniosynostosis syndromes, namely Apert, Crouzon and Pfeiffer syndromes, as well as in Jackson-Weis...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02751527

    authors: Wilkie AO

    更新日期:1996-05-01 00:00:00

  • Does early erythropoietin therapy decrease transfusions in anemia of prematurity?

    abstract:OBJECTIVE:To investigate the effect of early erythropoietin treatment on induction of erythropoiesis and the need for transfusion in Very Low Birth Weight (VLBW) infants with acute neonatal problems. METHODS:The study group consisted of 14 VLBW prematures with gestational ages less than 32 weeks who were given subcuta...

    journal_title:Indian journal of pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02722624

    authors: Atasay B,Günlemez A,Akar N,Arsan S

    更新日期:2002-05-01 00:00:00

  • Thrombocytopenic purpura as a presenting manifestation of tubercular lymphadenitis.

    abstract::A 11-year-old girl presented with thrombocytopenic purpura along with cervical lymphadenopathy. There was no hepatosplenomegaly; no evidence of microangiopathy; bone marrow examination was normal. Acid fast bacilli were seen in fine needle aspiration cytology of the lymph node. A diagnosis of tubercular lymphadenitis ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02723827

    authors: Bakhshi S,Kabra M,Iyer VK,Arya LS

    更新日期:2003-12-01 00:00:00

  • LY96, UPKIB mutations and TLR4, CD14, MBL polymorphisms in children with urinary tract infection.

    abstract:OBJECTIVE:To evaluate genetic variations of innate immune system such as mannose binding lectin (MBL), Toll like receptor 4 (TLR4), CD14, LY96 (MD2) and Uroplakin 1B (UPK1B) genes in children with recurrent urinary tract infection (UTI). METHODS:The study included 30 children with recurrent UTI and 30 healthy controls...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-011-0399-8

    authors: Ertan P,Berdeli A,Yilmaz O,Gonulal DA,Yuksel H

    更新日期:2011-10-01 00:00:00

  • Multicentric Castleman's disease in two cases.

    abstract::Castleman's disease is an atypical lymphoproliferative disorder having two types of presentation--the localized and the multicentric form. The localized form presents as a slowly growing mass with a relatively benign course. Multicentric Castleman's disease has a more aggressive clinical course with diffuse lymph node...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-007-0210-z

    authors: Sharma R,Seth R,Thavaraj V,Bagga A,Kabra SK,Karak AK,Atri S

    更新日期:2007-12-01 00:00:00

  • Systemic antifungal agents.

    abstract::Anti-fungal agents are classified under two major headings, systematic and topical agents. Only systematic anti-fungal agents will be discussed in this chapter. Since the discovery in 1955, amphotericin B has been the cornerstone of anti-fungal treatment. It is active against most species of fungi. However, Candida lu...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02752281

    authors: Abuhammour W,Habte-Gabr E

    更新日期:2001-07-01 00:00:00

  • Association between Anthropometric Indices, Body Composition and Bone Parameters in Thai Female Adolescents.

    abstract:OBJECTIVE:To investigate correlations between anthropometrics and body composition with bone parameters of the whole-body and lumbar spine in non-obese and obese Thai female adolescents. METHODS:This study was performed in 135 female adolescents aged 15 to 18 y enrolled in secondary schools in southern Thailand. Subje...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-017-2422-1

    authors: Khwanchuea R,Punsawad C

    更新日期:2017-12-01 00:00:00

  • Integrated Management of Childhood Illness (IMCI): a robust strategy.

    abstract::Integrated Management of Childhood Illness (IMCI), a strategy fostering holistic approach to child health and development, is built upon successful experiences gained from effective child health interventions like immunization, oral rehydration therapy, management of acute respiratory infections and improved infant fe...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02723776

    authors: Patwari AK,Raina N

    更新日期:2002-01-01 00:00:00

  • Physical growth and nutritional status of Garhwali girls.

    abstract:OBJECTIVE:The present study was conducted to evaluate physical growth and nutritional status of 214 school-going girls ranging in age from 5 to 12 years of rural area in Pauri Garhwal district of Uttaranchal. METHODS:Physical growth was evaluated using eleven standard anthropometric measurements viz., height, body wei...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02724181

    authors: Vashisht RN,Krishan K,Devlal S

    更新日期:2005-07-01 00:00:00

  • Postnatal weight velocity patterns in very low birthweight infants.

    abstract::The care of very-low-birth-weight infants has improved over the years with continuing changes in medical and nutritional management. In view of these changes, there is a need to study the pattern of postnatal weight gain. Postnatal weight gain patterns of 32 very-low-birth-weight infants were examined during the first...

    journal_title:Indian journal of pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02845210

    authors: Ozkan H,Uguz A,Haberal S

    更新日期:1997-05-01 00:00:00

  • The Journey of Newborn Screening: Inception to Conclusion.

    abstract:: ...

    journal_title:Indian journal of pediatrics

    pub_type: 社论

    doi:10.1007/s12098-017-2544-5

    authors: ICMR Task Force on Inherited Metabolic Disorders.

    更新日期:2018-11-01 00:00:00

  • Recurrent meningitis secondary to isolated C3 deficiency.

    abstract::A 5-year-old child presented with the second episode of meningitis when we started investigating her to find a cause for recurrent episode of meningitis. During this she suffered from a third attack after which she was diagnosed as having isolated C(3) deficiency. She was put on penicillin prophylaxis and vaccinated a...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0036-y

    authors: Singh DK,Rai R

    更新日期:2009-01-01 00:00:00

  • Platelet Activation Dynamics in Kawasaki Disease- Revisited.

    abstract:: ...

    journal_title:Indian journal of pediatrics

    pub_type: 评论,社论,评审

    doi:10.1007/s12098-019-02890-y

    authors: Vignesh P,Singh S

    更新日期:2019-03-01 00:00:00

  • Surgical therapy for the univentricular heart.

    abstract::The natural history of the univentricular physiology is determined primarily by the presence (severity) or absence of obstruction to pulmonary blood flow and secondarily by the single ventricular cardiomyopathy that develops in response to chronic volume overload. Important obstruction to pulmonary blood flow will aff...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02760487

    authors: Sharma R

    更新日期:2000-07-01 00:00:00

  • Multiple Intracranial Aneurysms in HIV Infection.

    abstract::Neurological findings in HIV are common and include cognitive impairment, microcephaly, nonspecific white matter lesions and seizures. Cerebral vasculopathy and stroke are uncommon and may be due to primary HIV vasculopathy or opportunistic infections such as tuberculosis and cryptococcal meningitis. The authors descr...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-016-2073-7

    authors: Dhawan SR,Gupta A,Gupta V,Singhi PD

    更新日期:2016-08-01 00:00:00

  • A Targeted Next Generation Sequencing Panel for Non-syndromic Early Onset Severe Obesity and Identification of Novel Likely -Pathogenic Variants in the MC4R and LEP Genes.

    abstract:OBJECTIVES:To screen for variants in the MC4R and LEP genes in 46 patients with clinical suspicion of non-syndromic early onset severe obesity (NEOSO). METHODS:Children with early onset obesity satisfying WHO criteria of obesity were studied. The MC4R and LEP genes were sequenced using a PCR amplicon based NGS on Illu...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-019-03129-6

    authors: Khadilkar V,Gogate N,Gangodkar P,Ranade S,Lohiya N,Ragte T,Patil K,Pilankar A,Anand S,Bapat A,Agarwal M,Kaushik K,Lote-Oke R,Khadilkar A,Phadke N

    更新日期:2020-02-01 00:00:00

  • Approach to a child with bleeding in the emergency room.

    abstract::A bleeding child is a cause of great concern and often, panic, for parents and pediatricians alike. Causes of bleeding could be trivial or secondary to an underlying bleeding disorder or a potentially serious systemic illness. Based on etiology, they can be categorized into disorders affecting platelets or the coagula...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-012-0918-2

    authors: Bansal D,Oberoi S,Marwaha RK,Singhi SC

    更新日期:2013-05-01 00:00:00

  • The making of a polio-free India.

    abstract::Rotary one of the largest non-government international organization focused mainly towards the up-liftment of the downtrodden worldwide, got involved in the Polio Eradication Program way back in 1979 with a five-year pledge to immunize about six million Philippine children from the crippling disease of poliomyelitis. ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02722705

    authors: Tandon R

    更新日期:2002-08-01 00:00:00

  • Effect of gender, birth weight and gestational age on serum 17-hydroxyprogesterone concentration and distribution among neonates in Saudi Arabia.

    abstract::Blood samples from 813 newborns were spotted on to filter paper and the 17-hydroxyprogesterone concentration was measured using the Delfia (R) fluorometric immunoassay. The median, mean, and standard deviation (SD) for the total population were 20, 21 and (11) nmol/L respectively. Males had significantly higher levels...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02761890

    authors: al-Nuaim AR,Abdullah MA,Stevens B,Zain M

    更新日期:1995-09-01 00:00:00

  • Kawasaki disease and the emerging coronary artery disease epidemic in India: is there a correlation?

    abstract::Although Kawasaki disease (KD) is now being increasingly reported from India, the vast majority of children with KD are still not being diagnosed and treated. A recent study from Chandigarh has shown that the incidence of KD is at least 4.54/100,000 children below 15 y of age. Extrapolations of this figure suggest tha...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-013-1229-y

    authors: Singh S,Aulakh R,Kawasaki T

    更新日期:2014-04-01 00:00:00

  • Outcome and prognostic factors seen in pediatric oncology patients admitted in PICU of a developing country.

    abstract:OBJECTIVE:To evaluate the outcome and prognostic factors for oncology patients in the PICU of a tertiary care centre in a developing country. METHODS:A retrospective chart review was done to assess the outcome of children with cancer in the pediatric intensive care unit (PICU) of a developing country from January 2000...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-011-0391-3

    authors: Akhtar N,Fadoo Z,Panju S,Haque A

    更新日期:2011-08-01 00:00:00

  • Management of anorectal malformation in neonates.

    abstract::Anorectal malformations are one of the commonest anomalies in the new born. Major advances have been made in the last decade in operative techniques to reconstruct this abnormality. The final outcome in these babies is dependent on careful planning and operative intervention in the neonatal period. The purpose of this...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02726272

    authors: Chowdhary SK,Gupta A,Samujh R,Narasimhan KL,Rao KL

    更新日期:1999-09-01 00:00:00

  • Prevalence of cryptosporidium in children with acute diarrhea.

    abstract::Cryptosporidium is an intestinal protozoa known to cause diarrhea in animals and more recently has been recognised as a cause of diarrhea in humans. The present study was designed to determine the prevalence of cryptosporidium as a cause of diarrhea in children. Faecal samples of 180 children admitted to the hospital ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02749728

    authors: Pherwani AV,Bhave SY,Bijm AM,Desai AG

    更新日期:1989-01-01 00:00:00

  • Mapping interpersonal communication between pediatricians and mothers: understandings, interdependencies and gaps.

    abstract::Interpersonal communication between pediatricians and mothers is both complex and interdependent. The mother is dependent on the pediatrician for her child's wellbeing and care along expertise-related dimensions for which she cannot provide. The pediatrician is dependent on the mother's ability to provide accurate inf...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-012-0934-2

    authors: Mookerjee D

    更新日期:2013-12-01 00:00:00

  • Prevalence of Developmental Co-ordination Disorder in School Children.

    abstract::Developmental co-ordination disorder (DCD) is a hidden complex childhood disorder seen in school aged children. There are only few Indian literatures supporting the prevalence of DCD among Indian school children but this current research has attempted to make a confirmatory diagnosis of DCD. Objective of the study was...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-020-03191-5

    authors: Sujatha B,Alagesan J,Lal DV,Rayna ABS

    更新日期:2020-06-01 00:00:00

  • Congenital airway abnormalities in neonates.

    abstract::Airway malformations such as laryngeal atresia, tracheal agenesis and subglottic stenosis are rare and present at birth with significant respiratory distress with or without stridor. There may be an initial improvement on bag and mask ventilation. Repeated attempts at intubation are met with failure. The related embry...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02726024

    authors: Sarkar N,Agarwal R,Das AK,Atri S,Aggarwal R,Deorari AK

    更新日期:2002-11-01 00:00:00