Abstract:
OBJECTIVES:To investigate factors involved in causing hypocalcemia in critically ill patients. METHODS:The patients aged 1 mo to 18 y, admitted to PICU at Nemazee Hospital, from May through November 2012, were reviewed. Those with impaired calcium hemostasis or on vitamin-D supplement were excluded. Calcitonin and parathyroid hormone levels were checked if ionized calcium level was less than 3.2 mg/d. Patient's demographic data, length of stay, Pediatric Risk of Mortality-III (PRISM-III) score, the need for mechanical ventilation, inotropic drug administration and outcome were recorded. RESULTS:Among the 294 patients enrolled in the study, the incidence of ionized hypocalcemia was 20.4 %. The mortality rate was 45 % in hypocalcemic groups and 24.8 % in normocalcemic patients. Highly significant negative correlations were found between serum ionized calcium, PRISM-III score (r = -0.371, P = 0.004), and calcitonin level (r = -0.256, P = 0.049), but no significant correlation between hypocalcemia and parathyroid hormone level (P = 0.206) was found. A significant difference was observed between survivor and non-survivor groups regarding PRISM-III score (P = 0.00), ionized calcium (P = 0.00), and calcitonin (P = 0.022) but not parathyroid hormone level (P = 0.206). CONCLUSIONS:Hypocalcemia was associated with increased mortality rate in PICU patients. A negative correlation was found between ionized calcium level and calcitonin. There was also a link between PTH level and severity of illness. It can therefore be concluded that evaluating serum ionized calcium, calcitonin, and PTH levels can be used as prognostic factors in critically ill patients.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Haghbin S,Serati Z,Sheibani N,Haghbin H,Karamifar Hdoi
10.1007/s12098-014-1536-ysubject
Has Abstractpub_date
2015-03-01 00:00:00pages
217-20issue
3eissn
0019-5456issn
0973-7693journal_volume
82pub_type
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journal_title:Indian journal of pediatrics
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journal_title:Indian journal of pediatrics
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journal_title:Indian journal of pediatrics
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journal_title:Indian journal of pediatrics
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abstract::Inorganic mercury poisoning is uncommon, but when it occurs it can result in severe, life threatening features and acute renal failure. A 2-year old well thriving child presented with alleged history of accidental ingestion of inorganic mercury chloride. He presented with evidence of corrosive trauma to the gastrointe...
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-007-0179-7
更新日期:2007-10-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-010-0030-4
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2323-3
更新日期:2017-07-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1574-5
更新日期:2015-04-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03311-1
更新日期:2021-01-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-010-0246-3
更新日期:2010-11-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2585-9
更新日期:2018-09-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-008-0011-z
更新日期:2008-01-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03519-1
更新日期:2020-10-08 00:00:00
abstract::Pediatric soft tissue sarcomas (STS) are a heterogeneous group of malignant tumors constituting about 7% of all cancer cases. Rhabdomyosarcomas (RMS) constitute about half of all soft tissue sarcomas in children, the rest being constituted by non- rhabdomyosarcoma soft tissue sarcomas (NRSTS). Most RMS present in youn...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-011-0560-4
更新日期:2012-07-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
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更新日期:2006-12-01 00:00:00
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journal_title:Indian journal of pediatrics
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更新日期:1990-01-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
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更新日期:2013-05-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03653-w
更新日期:2021-01-09 00:00:00
abstract::The reasons for comparatively low infant mortality rates in the Indian state of Kerala are examined. The importance of improvements in education and in the health care delivery system is stressed. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751009
更新日期:1985-09-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0032-2
更新日期:2010-03-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02724388
更新日期:2002-12-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0240-9
更新日期:2009-11-01 00:00:00
abstract::Fainting attack or syncope in children is a common occurrence, with vasovagal syncope being the commonest cause for majority of pediatric syncope. The aim of emergency room evaluation is not to miss the rare serious underlying disorder causing syncope. A complete detailed history of the event followed by physical exam...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0497-7
更新日期:2012-03-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-018-02851-x
更新日期:2019-06-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-008-0248-6
更新日期:2008-05-01 00:00:00
abstract::Developmental co-ordination disorder (DCD) is a hidden complex childhood disorder seen in school aged children. There are only few Indian literatures supporting the prevalence of DCD among Indian school children but this current research has attempted to make a confirmatory diagnosis of DCD. Objective of the study was...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03191-5
更新日期:2020-06-01 00:00:00