Microstructure and mechanical properties of hydroxyapatite ceramics with zirconia dispersion prepared by post-sintering.

abstract：:Chitosans with various degrees of deacetylation were synthesized by acetylation with acetic anhydride. These chitosans were evaluated for efficacy of nanoparticle formation, DNA binding efficiency, morphology, and in vitro and in vivo gene transfection efficiency. DNA binding efficacy was reduced as degree of deacetyl...

journal_title：Biomaterials

authors： Kiang T,Wen J,Lim HW,Leong KW

更新日期：2004-10-01 00:00:00

abstract：:Recently, engineering the surface of nanotherapeutics with biologics to provide them with superior biocompatibility and targeting towards pathological tissues has gained significant popularity. Although the functionalization of drug delivery vectors with cellular materials has been shown to provide synthetic particles...

journal_title：Biomaterials

authors： Evangelopoulos M,Parodi A,Martinez JO,Yazdi IK,Cevenini A,van de Ven AL,Quattrocchi N,Boada C,Taghipour N,Corbo C,Brown BS,Scaria S,Liu X,Ferrari M,Tasciotti E

更新日期：2016-03-01 00:00:00

abstract：:Upconversion fluorescent nanoparticles are becoming more widely used as imaging contrast agents, owing to their high resolution and penetration depth, and avoidance of tissue auto-fluorescence and photodamage to cells. Here, we synthesized upconversion fluorescent crystals from rare-earth Yb3+ and Ho3+ co-doped fluora...

journal_title：Biomaterials

authors： Hu X,Zhu J,Li X,Zhang X,Meng Q,Yuan L,Zhang J,Fu X,Duan X,Chen H,Ao Y

更新日期：2015-06-01 00:00:00

abstract：:Acute trauma or trauma associated with occlusal disturbance can produce tooth crack or fracture. Although several methods are proposed to treat the defect, however, the prognosis is generally poor. If the fusion of a tooth fracture by laser is possible, it will offer an alternative to extraction or at least serve as a...

journal_title：Biomaterials

authors： Lin CP,Tseng YC,Lin FH,Liao JD,Lan WH

更新日期：2001-03-01 00:00:00

abstract：:Recent advances in efficient microRNA (miRNA) delivery techniques using brain-targeted nanoparticles offer critical information for understanding the functional role of miRNAs in vivo, and for supporting targeted gene therapy in terms of treating miRNA-associated neurological diseases. Here, we report the rabies virus...

journal_title：Biomaterials

authors： Hwang DW,Son S,Jang J,Youn H,Lee S,Lee D,Lee YS,Jeong JM,Kim WJ,Lee DS

更新日期：2011-07-01 00:00:00

abstract：:Tubular vessels for tissue engineering are typically fabricated using a molding, dipping, or electrospinning technique. While these techniques provide some control over inner and outer diameters of the tube, they lack the ability to align the polymers or fibers of interest throughout the tube. This is an important asp...

journal_title：Biomaterials

authors： Lovett ML,Cannizzaro CM,Vunjak-Novakovic G,Kaplan DL

更新日期：2008-12-01 00:00:00

abstract：:Dental amalgam prepared from high copper and conventional alloys was evaluated for its compressive strength as a function of deformation rate. Results showed that the compressive strength rose to a maximum as deformation rate increased and then began to fall at higher deformation rates. Crack propagation predominated ...

journal_title：Biomaterials

authors： Zardiackas LD,Anderson L Jr

更新日期：1986-07-01 00:00:00

abstract：:Anti-angiogenic therapeutics has been investigated extensively for the treatment of retinal and choroidal vascular diseases, and diabetic retinopathy. Anti-Flt1 peptide of GNQWFI is an antagonistic peptide for vascular endothelial growth factor receptor 1 (VEGFR1 or Flt1) inhibiting VEGFR1-mediated endothelial cell mi...

journal_title：Biomaterials

authors： Oh EJ,Choi JS,Kim H,Joo CK,Hahn SK

更新日期：2011-04-01 00:00:00

abstract：:The objective of this study is to develop a carrier for the controlled release of bone morphogenetic protein-2 (BMP-2) suitable for enhancement of the bone regeneration activity. Hydrogels with different water contents were prepared through glutaraldehyde crosslinking of gelatin with an isoelectric point of 9.0 under ...

journal_title：Biomaterials

authors： Yamamoto M,Takahashi Y,Tabata Y

更新日期：2003-11-01 00:00:00

abstract：:In order to overcome the problem of rapid clearance of the polysaccharide hyaluronic acid (Hyal) in the treatment of osteoarthritis (OA), a 50% cross-linked Hyal hydrogel (Hyal 50%) was synthesised. The 50% refers to the amount of COOH groups of the polysaccharide involved in the cross-linking reaction. i.e. 50% of th...

journal_title：Biomaterials

authors： Barbucci R,Lamponi S,Borzacchiello A,Ambrosio L,Fini M,Torricelli P,Giardino R

更新日期：2002-12-01 00:00:00

abstract：:The effect of surface characteristics on the interaction of sterically stabilized polystyrene particles with mouse peritoneal macrophages was studied using a range of poloxamers and poloxamine as coating agents. The coated particles were characterized in terms of thickness of coating layer, surface charge and critical...

journal_title：Biomaterials

authors： Illum L,Jacobsen LO,Müller RH,Mak E,Davis SS

更新日期：1987-03-01 00:00:00

abstract：:Targeted therapy is needed for hepatitis B virus (HBV)-mediated hepatocellular carcinoma (HCC) which shows overexpression of HBV surface antigen (HBsAg). We previously developed scFv15, a human single-chain antibody against HBsAg. Here we tested the strategic feasibility of scFv15-mediated delivery of apoptotic effect...

journal_title：Biomaterials

authors： Yan B,Ouyang Q,Zhao Z,Cao F,Wang T,Jia X,Meng Y,Jiang S,Liu J,Chen R,Jia L,Zhang R,Wen W,Jin B,Chen S,Zhao J,Yang A

更新日期：2013-07-01 00:00:00

abstract：:Multiwalled carbon nanotubes (MWCNTs) are cut short and grafted with polyethylenimine (PEI) for further covalent conjugation to fluorescein isothiocyanate (FITC) and prostate stem cell antigen (PSCA) monoclonal antibody (mAb). The in vitro and in vivo toxicity data reveal that the as-prepared CNT-PEI(FITC)-mAb has goo...

journal_title：Biomaterials

authors： Wu H,Shi H,Zhang H,Wang X,Yang Y,Yu C,Hao C,Du J,Hu H,Yang S

更新日期：2014-07-01 00:00:00

abstract：:Previous work developing particle-based acellular, artificial antigen presenting cells (aAPCs) has focused exclusively on spherical platforms. To explore the role of shape, we generated ellipsoidal PLGA microparticles with varying aspect ratios (ARs) and synthesized aAPCs from them. The ellipsoidal biomimetic aAPCs wi...

journal_title：Biomaterials

authors： Sunshine JC,Perica K,Schneck JP,Green JJ

更新日期：2014-01-01 00:00:00

abstract：:The application of poly(hydroxybutyrate-co-hydroxyhexanoate) (PHBHHx) for sustained and controlled delivery of hydrophilic insulin was made possible by preparing insulin phospholipid complex loaded biodegradable PHBHHx nanoparticles (INS-PLC-NPs). The INS-PLC-NPs produced by a solvent evaporation method showed a spher...

journal_title：Biomaterials

authors： Peng Q,Zhang ZR,Gong T,Chen GQ,Sun X

更新日期：2012-02-01 00:00:00

abstract：:It was reported that nanoparticles with polysorbate 80 (Tween 80, T-80) coating represented tools used for delivering drugs to brain. Nevertheless, disputations were once aroused for some complications. Aimed to have a better understanding of the specific role of T-80 coating on nanoparticles and simplify the problem,...

journal_title：Biomaterials

authors： Sun W,Xie C,Wang H,Hu Y

更新日期：2004-07-01 00:00:00

abstract：:The aim of the present study was to test the hypothesis that oligonucleotides can be used for anchorage and slow release of osteogenic growth factors such as BMP to enhance the osteogenic activity of a titanium implant surface. Strands of 60-mer non-coding DNA oligonucleotides (ODN) were bound to an acid-etched sandbl...

journal_title：Biomaterials

authors： Schliephake H,Bötel C,Förster A,Schwenzer B,Reichert J,Scharnweber D

更新日期：2012-02-01 00:00:00

abstract：:In vivo and in vitro degradation of high molecular weight poly(L-lactide) used for internal bone fixation has been investigated. Within 3 months as-polymerized, microporous PLLA (Mv = 6.8-9.5 X 10(5] exhibited a massive strength-loss (sigma b = 68-75 MPa to sigma b = 4 MPa) and decrease of Mv (90-95%). At week 39, the...

journal_title：Biomaterials

authors： Leenslag JW,Pennings AJ,Bos RR,Rozema FR,Boering G

更新日期：1987-07-01 00:00:00

abstract：:An ideal scaffold that provides a combination of suitable mechanical properties along with biological signals is required for successful ligament/tendon regeneration in mesenchymal stem cell-based tissue engineering strategies. Among the various fibre-based scaffolds that have been used, hybrid fibrous scaffolds compr...

journal_title：Biomaterials

authors： Sahoo S,Toh SL,Goh JC

更新日期：2010-04-01 00:00:00

abstract：:It is well known that biomaterials play an important role in the regulation of adhesion and growth of a variety of cultured cell types. However, whether biomaterials are associated with the senescence of cultured cells is not known. The present work shows that the decrease of the hydrophobic property of poly (ethylene...

journal_title：Biomaterials

authors： Lou PJ,Chiu MY,Chou CC,Liao BW,Young TH

更新日期：2010-03-01 00:00:00

abstract：:Hydrogels are commonly used as artificial extracellular matrices for 3D cell culture and for tissue engineering. Viscoelastic hydrogels with tunable stress relaxation have recently been developed, and stress relaxation in the hydrogels has been found to play a key role in regulating cell behaviors such as differentiat...

journal_title：Biomaterials

authors： Nam S,Stowers R,Lou J,Xia Y,Chaudhuri O

更新日期：2019-04-01 00:00:00

abstract：:Using the recently developed surface modification technique, free amino groups have been introduced onto polyester-type polyurethane (PU) scaffolds. The introduction of these free amino groups increases the surface energy and provides a convenient way to further immobilize bioactive species such as gelatin, collagen o...

journal_title：Biomaterials

authors： Zhu Y,Gao C,He T,Shen J

更新日期：2004-02-01 00:00:00

abstract：:This article is a review of recent developments of polymer-related stents mainly employed in the coronary arteries, including polymer-coated stents, biostable stents and biodegradable stents. Polymer paving is covered as well. The problems with the stents currently investigated and the development of new stents are di...

journal_title：Biomaterials

authors： Peng T,Gibula P,Yao KD,Goosen MF

更新日期：1996-04-01 00:00:00

abstract：:Graphene oxide (GO) immunotoxicity is not clarified well up to date. Herein we reported the effects of GOs with and without polyvinylpyrrolidone (PVP) coating on human immune cells such as dendritic cells (DCs), T lymphocytes and macrophages. Human immune cells such as dendritic cells (DCs), T lymphocytes and macropha...

journal_title：Biomaterials

authors： Zhi X,Fang H,Bao C,Shen G,Zhang J,Wang K,Guo S,Wan T,Cui D

更新日期：2013-07-01 00:00:00

abstract：:The human heart cannot regenerate after an injury. Lost cardiomyocytes are replaced by scar tissue resulting in reduced cardiac function causing high morbidity and mortality. One possible solution to this problem is cardiac tissue engineering. Here, we have investigated the suitability of non-mulberry silk protein fib...

journal_title：Biomaterials

authors： Patra C,Talukdar S,Novoyatleva T,Velagala SR,Mühlfeld C,Kundu B,Kundu SC,Engel FB

更新日期：2012-03-01 00:00:00

abstract：:Three-dimensional constructs formed by cells embedded in an exogenous scaffold could not represent a faithful in vitro replica of native and functional tissues. In this work we produced an endogenous human skin equivalent by means of a tissue engineering process that induces the full morphogenesis of functional dermal...

journal_title：Biomaterials

authors： Casale C,Imparato G,Urciuolo F,Netti PA

更新日期：2016-09-01 00:00:00

abstract：:An urgent unmet need exists for early-stage treatment of spinal cord injury (SCI). Currently methylprednisolone is the only therapeutic agent used in clinics, for which the efficacy is controversial and the side effect is well-known. We demonstrated functional restoration of injured spinal cord by self-assembled nanop...

journal_title：Biomaterials

authors： Wu W,Lee SY,Wu X,Tyler JY,Wang H,Ouyang Z,Park K,Xu XM,Cheng JX

更新日期：2014-02-01 00:00:00

abstract：:The adsorption of chondroitin-4-sulphate (C4S) and heparin onto titanium has been studied in the absence and presence of bovine serum albumin (BSA). Isotherm data (0.02 M calcium acetate, pH 6.8) have shown that BSA in solution and BSA-coated titanium result in decreased adsorption for both C4S and heparin. For the BS...

journal_title：Biomaterials

authors： Hughes Wassell DT,Embery G

更新日期：1997-08-01 00:00:00

abstract：:Particle-associated periprosthetic osteolysis remains a major issue in joint replacement. Ongoing bone loss resulting from wear particle-induced inflammation is accompanied by continued attempts at bone repair. Previously we showed that mesenchymal stem cells (MSCs) are recruited systemically to bone exposed to contin...

journal_title：Biomaterials

authors： Gibon E,Yao Z,Rao AJ,Zwingenberger S,Batke B,Valladares R,Smith RL,Biswal S,Gambhir SS,Goodman SB

更新日期：2012-05-01 00:00:00

abstract：:Human platelet lysates (PLs), which contain multiple neurotrophins, have been proposed for treating neurodegenerative disorders, including Parkinson's disease (PD). However, current PLs suspended in plasma have high protein content and contain fibrinogen/fibrin and, following activation, also proteolytic and thromboge...

journal_title：Biomaterials

authors： Chou ML,Wu JW,Gouel F,Jonneaux A,Timmerman K,Renn TY,Laloux C,Chang HM,Lin LT,Devedjian JC,Devos D,Burnouf T

更新日期：2017-10-01 00:00:00