Abstract:
:Emerging strategies in cancer therapeutics link the genomic mutational and proteomic landscape, allowing intelligent reasoning on target selection. In this issue of Cancer Cell, Piccinin and colleagues use this approach to demonstrate that the mesenchymal protein Twist1 inhibits p53, providing a novel target for reactivation of p53 in human sarcoma.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Hupp TR,Hayward RL,Vojtesek Bdoi
10.1016/j.ccr.2012.08.020subject
Has Abstractpub_date
2012-09-11 00:00:00pages
283-5issue
3eissn
1535-6108issn
1878-3686pii
S1535-6108(12)00361-3journal_volume
22pub_type
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