Abstract:
:Bacteria, like mammals, have to constantly defend themselves from viral attack. Like mammals, they use both innate and adaptive defense mechanisms. In this point of view we highlight the commonalities between defense systems of bacteria and mammals. Our focus is on the recently discovered bacterial adaptive immune system, the clustered regularly interspaced short palindromic repeats (CRISPR) and their associated proteins (Cas). We suggest that fundamental aspects of CRISPR/Cas immunity may be viewed in light of the vast accumulated knowledge on the mammalian immune system, and propose that further insights will be revealed by thorough comparison between the systems.
journal_name
RNA Bioljournal_title
RNA biologyauthors
Goren M,Yosef I,Edgar R,Qimron Udoi
10.4161/rna.20177subject
Has Abstractpub_date
2012-05-01 00:00:00pages
549-54issue
5eissn
1547-6286issn
1555-8584pii
20177journal_volume
9pub_type
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