Abstract:
:In recent years, the residential exposure to radon daughters has become a cause for concern as a contributing factor for lung cancer. In order to evaluate the population's risk consequences of different interpretations of the results of epidemiological studies in cohorts of uranium miners, a simulation model has been formulated. In the model, a defined population is generated as a set of individuals with a distribution of characteristics and exposures as they are known to exist in the defined population. The risk for each individual of being diagnosed with lung cancer in the next year can be determined, based on whatever interpretation is being evaluated. The risk can then be translated into an annual number of cases, and suitable controls can be identified as well. Both cases and controls have their individual risk factors of radon daughter exposure and history of cigarette smoking, and it is possible to subject these cases and controls to statistical analyses appropriate to case-control studies. This analysis can be used to see to what extent the original risk equation can be retrieved, and to what extent other risk formulations can be rejected. The simulation model can be used to evaluate conclusions drawn from prior epidemiological studies, as well as for evaluations of the effectiveness of designs for proposed studies.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Stolwijk JA,Canny PFdoi
10.1093/ije/19.supplement_1.s73subject
Has Abstractpub_date
1990-01-01 00:00:00pages
S73-8eissn
0300-5771issn
1464-3685journal_volume
19 Suppl 1pub_type
杂志文章abstract:Background:An increasing number of original studies suggest that exposure to shift work could be associated with the risk of overweight and obesity, but the results remain conflicted and inconclusive. This study aimed to quantitatively synthesize available epidemiological evidence on the association between shift work ...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析
doi:10.1093/ije/dyy079
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:While the COVID-19 outbreak in China now appears suppressed, Europe and the USA have become the epicentres, both reporting many more deaths than China. Responding to the pandemic, Sweden has taken a different approach aiming to mitigate, not suppress, community transmission, by using physical distancing with...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyaa121
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The stability of mammalian serum and urine in large metabolomic investigations is essential for accurate, valid and reproducible studies. The stability of mammalian serum and urine, either processed immediately by freezing at -80 degrees C or stored at 4 degrees C for 24 h before being frozen, was compared i...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dym281
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:The prevalence of obesity has increased rapidly in most developed countries in the last decades, and this rise is now spreading to developing countries. Childhood obesity is also increasing. The UK government has set a target to halt the rise in childhood obesity by 2010. Dietary recommendations are a centra...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/dyl208
更新日期:2006-12-01 00:00:00
abstract::There are certain health risks associated with recreational exposure to bacteriologically polluted water. In this study, 27% (21/77) of swimmers who took part in a snorkel swimming event, experienced gastrointestinal symptoms within 48 hours of entering the untreated water. The incidence of these symptoms was statisti...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.4.624
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND:The relationship between income and health is usually thought to be curvilinear, but previous studies have yielded inconsistent results. We therefore examined the shape of the relationship between household equivalent income and self-assessed health in seven European countries. METHODS:Data were obtained fr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh338
更新日期:2005-04-01 00:00:00
abstract::The relationship between pet ownership and respiratory allergy and symptoms was investigated in a population of 3344 Dutch children of 6-12 years old. Pet ownership was defined by the presence of cats, dogs, birds and/or rodents in the home. The reported prevalence of respiratory allergy and symptoms was lower among c...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.2.338
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND:Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism. METHODS:We used multivariable linear regression and a negative control design to examine offspring epigenome-wide DNA me...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyv042
更新日期:2015-08-01 00:00:00
abstract::Operational research (OR) analysis provides information and systems to support decision making. In health care there are examples of OR being used to support decisions surrounding both the organization of health services and the treatment of individual patients. However, its uptake is currently low in spite of the inc...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.supplement_1.s90
更新日期:1995-01-01 00:00:00
abstract::Coronary heart disease (CHD) is regarded as a disease of developed 'western' societies. Within developed societies, however, CHD is typically a disease of the less affluent socioeconomic classes. This has not always been the case. Forty years ago. CHD was reported to be more common among the upper social classes. In N...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.2.393
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Aetiological profiles of non-Hodgkin's lymphoma (NHL) may differ depending upon whether the disease is inheritance-related or sporadic. Because familial risk (a probable surrogate of inheritance-relatedness) of NHL is influenced by haematolymphoproliferative malignancies (HLPM), we evaluated whether non-fami...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/30.4.818
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Nicotine dependence is a significant public health problem. This study attempted to characterize the prevalence and familial aggregation of nicotine dependence in China. METHODS:In 1998, we initiated a community-based cross-sectional study among residents of the Yuexi County in Anqing, China. A total of 991...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ije/29.2.248
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVES:To examine educational gradients in overall and cause-specific mortality among elderly married men and women and their spouses. METHODS:Using the census-based Israel Longitudinal Mortality Study (1983-92), 13 573 married men and 6563 married women were identified who were aged 70-89 years at baseline. Cox p...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyi185
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:In spite of an improving trend, childhood mortality in rural sub-Saharan Africa remains high and has recently risen in some countries. The factors associated with the long-term decline in childhood mortality are poorly known, due to a lack of data. METHODS:A Senegalese rural population has been under demogr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/30.6.1286
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The study examines whether self-rated health forms a continuum from poor through average to good health in terms of two groups of health-related variables. METHODS:The data come from the 1994 Finnish Survey on Living Conditions, a representative sample of Finnish men and women aged 25 years or older (n = 72...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/27.2.208
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Melioidosis, or infection with Pseudomonas pseudomallei is an important cause of morbidity and mortality in South East Asia and Northern Australia. The epidemiology of melioidosis in Ubon Ratchatani, Northeast Thailand was studied over a 5-year period from 1987 to 1991. METHODS:Rates and, when possible, the...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.5.1082
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:To assess the impact of water sanitation and sewage disposal, part of a major environmental control programme in Rio de Janeiro, we carried out sero-prevalence studies for Hepatitis A virus (HAV) in three micro-regions in Rio de Janeiro. Each region varied with regard to level of sanitation. We are intereste...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.4.776
更新日期:1999-08-01 00:00:00
abstract::In recent years a strong case has been made in support of a viral aetiology for at least some primary hepatocellular carcinoma (PHC) in areas of low incidence. By pooling routinely collected cancer registration and infection data, study of the relationship between hepatitis B virus (HBV) infection and the incidence of...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.1.60
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:In epidemiological studies researchers often depend on proxies to obtain information when primary subjects are unavailable. However, relatively few studies have performed formal statistical inference to assess agreement among proxy informants and primary study subjects. In this paper, we consider inference p...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/29.6.1070
更新日期:2000-12-01 00:00:00
abstract::In this study in 437 women born in 1948 selected from five European towns we show that several anthropometric measurements are consistently and significantly associated with a metabolic risk profile in premenopausal women of 38 years of age. Among the circumferences, breast and waist circumference were, after adjustme...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.2.303
更新日期:1990-06-01 00:00:00
abstract::Mortalities from selected causes from 1973 to 1982 among Koreans, Chinese, and Americans residing in Japan were compared with those of Japanese. In the Korean population, besides the well-documented excess in mortalities from liver cancer, lung cancer, liver cirrhosis and male tuberculosis, a rather prominent elevatio...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.3.415
更新日期:1987-09-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh151
更新日期:2004-10-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.supplement_1.s39
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Exercise can suppress androgen production and may thus decrease the risk of prostate cancer. However, findings from epidemiological studies assessing physical activity and risk of prostate cancer are inconsistent. METHODS:We prospectively examined the association between physical activity and prostate cance...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章
doi:10.1093/ije/29.1.29
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:We enrolled a cohort of primary schoolchildren with a history of wheeze (n = 148) in an 11-month longitudinal study to examine the relationship between ambient ozone concentrations and peak expiratory flow rate. METHODS:Enrolled children recorded peak expiratory flow rates (PEFR) twice daily. We obtained ai...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::This population-based study examines whether dietary intake in middle-aged Italian women is influenced by alcohol drinking habits. The 499 participants were interviewed using a dietary history questionnaire designed to investigate alcohol consumption. Mean intake of total and non-alcohol energy increased progressively...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.3.663
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Meta-analysis of randomized controlled trials (RCTs) is usually based on trials where patients are randomized individually into two different, parallel, treatment groups. This paper concentrates on RCTs of a different design-two-period, two-treatment cross-over trials. METHODS:The characteristics of these t...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/31.1.140
更新日期:2002-02-01 00:00:00
abstract:Background:We studied associations of number of daily cigarettes in the first trimester with placental weight and birthweight in women who smoked throughout pregnancy, and in women who stopped smoking after the first trimester. Methods:We included all women with delivery of a singleton in Norway (n = 698 891) during 1...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy110
更新日期:2018-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::A case-control study of rotavirus diarrhoea in Apache children up to two years old was conducted at the White Mountain Apache reservation from 1 May through 15 December 1985 to identify risk factors for rotavirus diarrhoea. The mothers of fifty cases, forty-five hospital controls and twenty-five neighbourhood controls...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.3.715
更新日期:1990-09-01 00:00:00