Alveolysin, the thiol-activated toxin of Bacillus alvei, is homologous to listeriolysin O, perfringolysin O, pneumolysin, and streptolysin O and contains a single cysteine.

Abstract:

:The gene coding for alveolysin, the thiol-activated toxin produced by Bacillus alvei, has been cloned by means of an oligonucleotide based on the known N-terminal sequence of the secreted protein. The complete nucleotide sequence of the gene has been determined. The deduced amino acid sequence of alveolysin shows that alveolysin shares homologies with listeriolysin O, perfringolysin O, pneumolysin, and streptolysin O. Alveolysin, like the other members of the family, contains a single cysteine in the conserved peptide sequence ECTGLA WEWWR.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Geoffroy C,Mengaud J,Alouf JE,Cossart P

doi

10.1128/jb.172.12.7301-7305.1990

subject

Has Abstract

pub_date

1990-12-01 00:00:00

pages

7301-5

issue

12

eissn

0021-9193

issn

1098-5530

journal_volume

172

pub_type

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