Abstract:
:Cryptocaryon irritans is one of the most important ectoparasites of marine fish. To identify the potential role of immune-related genes in antiparasitic immune responses in fish, we monitored the expression change of IL-8, COX-2, C-type lectin and transferrin in local and systemic immune organs of orange-spotted grouper post-C. irritans infection. IL-8 expression was up-regulated during the course of infection in the skin, while COX-2 and transferrin expression was up-regulated in the gill. COX-2 expression was significantly down-regulated in the spleen (0·7-5% of its control) and head kidney (0·5-4% of its control) post-primary infection. Transferrin expression was also down-regulated in the spleen and head kidney from 6 h to 5 days post-primary infection. However, C-type lectin expression was up-regulated in all tested organs post-infection, with the exception of day 7 in the spleen post-primary infection where the expression level was slightly down-regulated (44% of its control). These results suggest that these four immune-related genes play an important role in grouper anti-C. irritans infection and that local immune organs as the active organs contribute more than systemic immune organs to this course.
journal_name
Parasite Immunoljournal_title
Parasite immunologyauthors
Li YW,Dan XM,Zhang TW,Luo XC,Li AXdoi
10.1111/j.1365-3024.2011.01337.xsubject
Has Abstractpub_date
2011-12-01 00:00:00pages
679-987issue
12eissn
0141-9838issn
1365-3024journal_volume
33pub_type
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journal_title:Parasite immunology
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journal_title:Parasite immunology
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journal_title:Parasite immunology
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journal_title:Parasite immunology
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doi:10.1111/j.1365-3024.2009.01103.x
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journal_title:Parasite immunology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3024.2010.01224.x
更新日期:2010-08-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:2016-06-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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doi:10.1046/j.1365-3024.2000.00307.x
更新日期:2000-06-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.1995.tb01021.x
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