Genetic control of immunity to Heligmosomoides polygyrus: fixed H-2 E positive but not H-2 negative cells can present antigen to a parasite-specific T cell hybridoma.

abstract：:Antibodies and B cells are critical in the protective immune response to the blood stage of the malaria parasite, Plasmodium chabaudi. However, little is known about the development of memory B cells and their differentiation into plasma cells during infection or after re-infection. Here we have shown that B cells wit...

journal_title：Parasite immunology

authors： Stephens R,Ndungu FM,Langhorne J

更新日期：2009-01-01 00:00:00

abstract：:The role of CD4+ and CD8+ T lymphocytes in the development of a protective immune response against Cryptosporidium muris infection was studied by the reconstitution of severe combined immunodeficient (SCID) mice with well-defined populations of either naive or immune CD8+ or CD4+ T lymphocytes. Adoptive transfer of bo...

journal_title：Parasite immunology

authors： Kváč M,Kodádková A,Sak B,Květoňová D,Jalovecká M,Rost M,Salát J

更新日期：2011-04-01 00:00:00

abstract：:Analysis by one-dimensional (1-D) SDS-PAGE/Western blotting of whole mite extract (larval and adult stages) with sheep sera taken 0-84 days after infection with the sheep scab mite, Psoroptes ovis revealed a progressive IgE antibody response, with a dominant high molecular weight allergen (MW 180 kDa) detected early d...

journal_title：Parasite immunology

authors： Huntley JF,Machell J,Nisbet AJ,Van den Broek A,Chua KY,Cheong N,Hales BJ,Thomas WR

更新日期：2004-08-01 00:00:00

abstract：:Changes in phagocytic and adherent cell numbers were compared during the course of infections of mice with Plasmodium yoelii (Py) and P. berghei (Pb) and in vaccinated mice challenged with homologous parasites. Nucleated cells in the spleen increased in number in Py-infected mice and were maximal at the time of recove...

journal_title：Parasite immunology

authors： Lelchuk R,Taverne J,Agomo PU,Playfair JH

更新日期：1979-04-01 00:00:00

abstract：:Dirofilaria immitis is the agent of the heartworm disease in canids and felids, and of pulmonary dirofilariosis in man. Like other filariae, D. immitis harbours endosymbion Wolbachia bacteriae. In this work we analyse the response of specific IgE antibodies against both D. immitis antigens and the Wolbachia surface pr...

journal_title：Parasite immunology

authors： Pou-Barreto C,Quispe-Ricalde MA,Morchón R,Vázquez C,Genchi M,Postigo I,Valladares B,Simón F

更新日期：2008-11-01 00:00:00

abstract：:We assayed the vaccine potentialities of a recombinant S. bovis-derived glutathione S-transferase (rSb28GST), member of a molecular family already shown to have protective capacities in the S. mansoni and S. japonicum models. Injection of the rSb28GST in Freund's Complete Adjuvant resulted in good specific IgG respons...

journal_title：Parasite immunology

authors： Boulanger D,Trottein F,Mauny F,Bremond P,Couret D,Pierce RJ,Kadri S,Godin C,Sellin E,Lecocq JP

更新日期：1994-08-01 00:00:00

abstract：:An indirect enzyme linked immunsorbent assay (ELISA) for detection of antibodies to Neospora caninum in serum from dogs is described. Extracted tachyzoite proteins incorporated into immunostimulating complexes (iscoms) were used as coating antigen. A mixture of a monoclonal antibody to dog immunoglobulin G and a horse...

journal_title：Parasite immunology

authors： Björkman C,Lundén A,Holmdahl J,Barber J,Trees AJ,Uggla A

更新日期：1994-12-01 00:00:00

abstract：:Previous studies have shown that Leishmania elongation initiation factor (LeIF) antigen causes a partial immunity against leishmaniasis. The antigen develops type I immunity by overexpression of inflammatory cytokines such as interleukin-12 (IL-12), IFN-γ and TNF-α. Therefore, We evaluated immune responses induced by ...

journal_title：Parasite immunology

authors： Maspi N,Ghaffarifar F,Sharifi Z,Dalimi A

更新日期：2016-04-01 00:00:00

abstract：:The life cycle of Taenia solium, the pork tapeworm, is continuously closed in many rural settings in developing countries when free roaming pigs ingest human stools containing T. solium eggs and develop cysticercosis, and humans ingest pork infected with cystic larvae and develop intestinal taeniasis, or may also acci...

journal_title：Parasite immunology

authors： Garcia HH,Rodriguez S,Friedland JS,Cysticercosis Working Group in Peru.

更新日期：2014-08-01 00:00:00

abstract：:Translationally controlled tumour protein (TCTP) may play an important role in the establishment or maintenance of parasitemia in a malarial infection. In this study, the potential of TCTP as a malaria vaccine was investigated in two trials. In the initial vaccine trial, Plasmodium falciparum TCTP (PfTCTP) was express...

journal_title：Parasite immunology

authors： Taylor KJ,Van TT,MacDonald SM,Meshnick SR,Fernley RT,Macreadie IG,Smooker PM

更新日期：2015-01-01 00:00:00

abstract：:The zymosan-triggered chemiluminescence response of peritoneal exudate cells from mice infected with relatively virulent or avirulent Toxoplasma gondii strains was examined at various intervals after infection. Toxoplasma infections increased the background chemiluminescence compared with controls, but higher values w...

journal_title：Parasite immunology

authors： Masihi KN,Werner H,Gillert KE,Lange W

更新日期：1984-05-01 00:00:00

abstract：:Mice can be immunized to Plasmodium vinckei by repeated infections followed by cure. Such immunity is dependent on CD4 T cells and an architecturally modified spleen, but has little requirement for antibody. Thus, athymic mice can be exposed to P. vinckei and cured, but do not develop immunity. They are resistant to c...

journal_title：Parasite immunology

authors： Winkel KD,Good MF

更新日期：1991-09-01 00:00:00

abstract：:Serum antibody responses of mice exposed to Philippine isolates of Schistosoma japonicum have been analysed by immunoprecipitation of exogenously radiolabelled antigens extracted from adult worms. Attention was focused on labelled protein antigens differentially recognized by sera of mice that differ genetically in th...

journal_title：Parasite immunology

authors： Mitchell GF,Beall JA,Cruise KM,Tiu WU,Garcia EG

更新日期：1985-03-01 00:00:00

abstract：AIMS:Our aim was to investigate the skin-homing T-cell immune responses triggered in patients with Demodex infestation and/or rosacea. METHODS:Collected whole blood samples were divided into four groups: control subjects; nonrosacea patients with Demodex infestation (Demodex group); papulopustular rosacea (PPR) patien...

journal_title：Parasite immunology

authors： Gazi U,Gureser AS,Oztekin A,Karasartova D,Kosar-Acar N,Derici MK,Artuz F,Mumcuoglu KY,Taylan-Ozkan A

更新日期：2019-08-01 00:00:00

abstract：:A whole-killed malaria blood-stage vaccine (WKV) is promising in reducing the morbidity and mortality of malaria patients, but its efficacy needs to be improved. We found that the antimalarial drug chloroquine could augment the protective efficacy of the WKV of Plasmodium yoelii. The direct antimalarial effect of chlo...

journal_title：Parasite immunology

authors： Fu Y,Lu X,Zhu F,Zhao Y,Ding Y,Ye L,Guo B,Liu T,Xu W

更新日期：2020-01-01 00:00:00

abstract：:Infective forms of Trypanosoma cruzi, the parasite that causes Chagas' disease, express on their surface an enzyme denominated trans-sialidase (TS). The present study was designed to evaluate the naturally acquired immune responses to a bacterial recombinant protein representing the catalytic domain of TS in chronical...

journal_title：Parasite immunology

authors： Ribeirão M,Pereira-Chioccola VL,Rénia L,Augusto Fragata Filho A,Schenkman S,Rodrigues MM

更新日期：2000-01-01 00:00:00

abstract：:Peripheral blood eosinophilia, histology of skeletal muscle and brain, and larval recovery were compared between congenitally athymic nude mice (nu/nu) and thymus-bearing heterozygous littermates (nu/+) for 6 weeks following oral infection with Toxocara canis eggs. By comparing patterns of peripheral blood eosinophil ...

journal_title：Parasite immunology

authors： Sugane K,Oshima T

更新日期：1982-09-01 00:00:00

abstract：:Trypanosoma congolense is one of the main species responsible for Animal African Trypanosomosis (AAT). As preventive vaccination strategies for AAT have been unsuccessful so far, investigating the mechanisms underlying vaccine failure has to be prioritized. In T. brucei and T. vivax infections, recent studies revealed...

journal_title：Parasite immunology

authors： Obishakin E,de Trez C,Magez S

更新日期：2014-05-01 00:00:00

abstract：:The number of individuals catching schistosomiasis has increased with the popularity of 'primitive tourism' in Africa. Highly immunogenic material originating from the intestine of intravascular adult schistosomes gives rise to an antibody response making possible early identification of infected individuals using ser...

journal_title：Parasite immunology

authors： Thors C,Linder E

更新日期：1998-10-01 00:00:00

abstract：:Fasciola hepatica infection has been shown to suppress sheep lymphocyte proliferation in vitro and this is at least partially attributable to excretory/secretory products (ES) released by F. hepatica parasites. We identified a suppressive component in ES by analysing the effect of ES fractions, separated by gel filtra...

journal_title：Parasite immunology

authors： Prowse RK,Chaplin P,Robinson HC,Spithill TW

更新日期：2002-02-01 00:00:00

abstract：:African trypanosomes cause human and animal African trypanosomiases, which are chronic, debilitating and often fatal diseases of people and livestock in sub-Saharan Africa. The extracellular protozoan parasites are exemplars of antigenic variation. They direct host-protective B-cell and T-cell immune responses towards...

journal_title：Parasite immunology

authors： Black SJ,Mansfield JM

更新日期：2016-12-01 00:00:00

abstract：:Very little has been reported comparing resistance to coccidiosis in fast or slow growing broilers, the latter of which are becoming more prevalent in the broiler industry. We examined mRNA expression in the intestines of fast and slow growing broilers following Eimeria infection. We show that by day 13 post-infection...

journal_title：Parasite immunology

authors： Giles T,Sakkas P,Belkhiri A,Barrow P,Kyriazakis I,Foster N

更新日期：2019-09-01 00:00:00

abstract：:In order to characterize immunodominant components of T. spiralis a workshop was organized. In this the reactivity of monoclonal and polyclonal antibodies, provided by different research groups, towards total extracts from adult, new born larvae and muscle larvae as well as to excretory/secretory components of muscle ...

journal_title：Parasite immunology

authors： Ortega-Pierres MG,Yepez-Mulia L,Homan W,Gamble HR,Lim PL,Takahashi Y,Wassom DI,Appleton JA

更新日期：1996-06-01 00:00:00

abstract：:Particular immunopathological features and their effects on the vascular permeability of different ocular structures were analysed in two dogs naturally infected by Leishmania infantum. The existence of specific anti-Leishmania immunoglobulin G (IgG) in the aqueous humour was confirmed by the ELISA technique. There wa...

journal_title：Parasite immunology

authors： García-Alonso M,Blanco A,Reina D,Serrano FJ,Alonso C,Nieto CG

更新日期：1996-12-01 00:00:00

abstract：:We describe an ELISA for trophozoite-specific IgA in the intestinal secretions of mice infected with Giardia muris. Using this method, trophozoite-specific IgA was demonstrated in intestinal secretions of Giardia-infected immunocompetent BALB/c mice. Such antibody was undetectable in the intestinal secretions of Giard...

journal_title：Parasite immunology

authors： Heyworth MF,Kung JE,Caplin AB

更新日期：1988-11-01 00:00:00

abstract：:The present study was designed to investigate the role of neutrophils during the development of Schistosoma japonicum egg granulomas, in C57BL/6 and CBA mice. Laid eggs were implanted into the liver and monoclonal antibody, RB6-8C5, was used to eliminate neutrophils. After daily antibody treatment between days 9 and 1...

journal_title：Parasite immunology

authors： Hirata M,Hara T,Kage M,Fukuma T,Sendo F

更新日期：2002-09-01 00:00:00

abstract：:The humoral responses of eight cats infected with Brugia pahangi to somatic antigens from all life-cycle stages were examined quantitatively by ELISA and qualitatively by immunoblotting for almost a year post infection. Six cats spontaneously became amicrofilaraemic: their production of IgG antibodies against somatic ...

journal_title：Parasite immunology

authors： Fletcher C,Birch DW,Samad R,Denham DA

更新日期：1986-07-01 00:00:00

abstract：:Recent advances in molecular genetics and in imaging mean that it is now increasingly feasible to image biological processes within helminth parasites and to visualize interactions between worms and their hosts. Moreover, other innovative imaging approaches that are not dependent on transgenic parasites have been appl...

journal_title：Parasite immunology

authors： Pearce EJ,Lok JB

更新日期：2013-09-01 00:00:00

abstract：:Onchocerciasis is caused by the filarial nematode Onchocerca volvulus and is a major public health problem in West and Central Africa. With only partial and long-term treatment currently available, there is a need to develop a suitable vaccine. We analysed the antibody response to infective L3 larvae because this stag...

journal_title：Parasite immunology

authors： Faulkner H,Gardon J,Kamgno J,Enyong P,Boussinesq M,Bradley JE

更新日期：2001-09-01 00:00:00

abstract：:Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human) and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tape...

journal_title：Parasite immunology

authors： Arora N,Tripathi S,Kumar P,Mondal P,Mishra A,Prasad A

更新日期：2017-07-01 00:00:00