Galectin and aldolase-like molecules are responsible for the specific IgE response in humans exposed to Dirofilaria immitis.

abstract：BACKGROUND:More than 11 million people were estimated to have been infected by Schistosoma japonicum in China before the 1950s. However, few studies have been conducted to evaluate the longitudinal effects of previous schistosome infection (PSI). OBJECTIVE:We aimed to evaluate the association of PSI with fatty liver a...

journal_title：Parasite immunology

authors： Zou ZQ,Liu M,Zhong HQ,Guan GY

更新日期：2021-01-17 00:00:00

abstract：:African trypanosomes are well known for their ability to avoid immune elimination by switching the immunodominant variant surface glycoprotein (VSG) coat during infection. However, antigenic variation is only one of several means by which trypanosomes manipulate the immune system of their hosts. In this article, the r...

journal_title：Parasite immunology

authors： Mansfield JM,Paulnock DM

更新日期：2005-10-01 00:00:00

abstract：:Naegleria fowleri, a free-living amoeba, is the causative pathogen of primary amoebic meningoencephalitis in humans and experimental mice. N. fowleri is capable of destroying tissues and host cells through lytic necrosis. However, the mechanism by which N. fowleri induces host cell death is unknown. Electron microscop...

journal_title：Parasite immunology

authors： Song KJ,Jang YS,Lee YA,Kim KA,Lee SK,Shin MH

更新日期：2011-07-01 00:00:00

abstract：:We have cloned the cDNA of TBA-1, the Nematode polyprotein allergen (NPA) of Toxocara canis and found it to be most similar to ABA-1, the Ascaris NPA, on the basis of amino acid sequence. We could study the antigenic properties of an E-coli synthesized fusion protein prepared with the cloned gene since no glycosylatio...

journal_title：Parasite immunology

authors： Yahiro S,Cain G,Butler JE

更新日期：1998-08-01 00:00:00

abstract：:We have characterized various anti-schistosomular surface MoAbs previously shown to partially block in-vitro killing of schistosomula by human sera and eosinophils (Dunne et al. 1987). Immunodiffusion analysis showed that four IgM and one IgG3 MoAbs recognized periodate sensitive epitopes on the same molecular species...

journal_title：Parasite immunology

authors： Bickle QD,Andrews BJ

更新日期：1988-03-01 00:00:00

abstract：:Peripheral blood eosinophilia, histology of skeletal muscle and brain, and larval recovery were compared between congenitally athymic nude mice (nu/nu) and thymus-bearing heterozygous littermates (nu/+) for 6 weeks following oral infection with Toxocara canis eggs. By comparing patterns of peripheral blood eosinophil ...

journal_title：Parasite immunology

authors： Sugane K,Oshima T

更新日期：1982-09-01 00:00:00

abstract：:Cysticercosis is acquired when swine ingest human faeces contaminated with Taenia solium eggs. Humans become tapeworm carriers when they ingest infected pork meat. They can also develop cysticercosis after inadvertently swallowing T. solium eggs. Human neurocysticercosis (NCC) is considered as a public health problem ...

journal_title：Parasite immunology

authors： Flisser A,Gyorkos TW

更新日期：2007-12-01 00:00:00

abstract：:Serum from cats (Felis catus) that were repeatedly infected with Brugia pahangi and had become amicrofilaraemic (mf-ve) was injected intravenously into microfilaraemic (mf+ve) cats. If more than 1 microliter of immune serum per 1000 mf was injected, microfilarial counts fell dramatically within minutes and, in some ca...

journal_title：Parasite immunology

authors： Medeiros F,Baldwin CI,Denham DA

更新日期：1996-02-01 00:00:00

abstract：:Cryptocaryon irritans is one of the most important ectoparasites of marine fish. To identify the potential role of immune-related genes in antiparasitic immune responses in fish, we monitored the expression change of IL-8, COX-2, C-type lectin and transferrin in local and systemic immune organs of orange-spotted group...

journal_title：Parasite immunology

authors： Li YW,Dan XM,Zhang TW,Luo XC,Li AX

更新日期：2011-12-01 00:00:00

abstract：:The development of a malaria vaccine is a priority for improved and sustained malaria control. Optimal use of a vaccine in Africa will only be achieved if it can be delivered through the Expanded Programme of Immunization (EPI). We have completed a trial of the peptide vaccine SPf66 in Tanzanian infants, given alongsi...

journal_title：Parasite immunology

authors： Galindo CM,Acosta CJ,Schellenberg D,Aponte JJ,Roca A,Oettli A,Urassa H,Armstrong Schellenberg J,Kahigwa E,Ascaso C,Mshinda H,Lwilla F,Vidal J,Menendez C,Tanner M,Alonso PL

更新日期：2000-09-01 00:00:00

abstract：:Modulation of macrophage/dendritic cell (DC) cytokine production by the filarial nematode phosphorylcholine (PC)-containing product, ES-62, is mediated by Toll-like receptor (TLR) 4 and signal transduction depends on the TLR adaptor MyD88. Intriguingly, comparison of TLR4 knock-out (ko) mice with TLR4 mutant C3H/HeJ m...

journal_title：Parasite immunology

authors： Goodridge HS,McGuiness S,Houston KM,Egan CA,Al-Riyami L,Alcocer MJ,Harnett MM,Harnett W

更新日期：2007-03-01 00:00:00

abstract：:A pilot safety and immunogenicity trial of the malaria vaccine SPf66 was undertaken in The Gambia in 1993. One hundred and fifty infants aged 6-11 months were immunized with either 0.5 mg or 1.0 mg of SPf66 produced either in Colombia or in the USA or with a control vaccine. Children who received SPf66 experienced mor...

journal_title：Parasite immunology

authors： Bojang KA,Obaro SK,Leach A,D'Alessandro U,Bennett S,Metzger W,Ballou WR,Targett GA,Greenwood BM

更新日期：1997-12-01 00:00:00

abstract：:The number of individuals catching schistosomiasis has increased with the popularity of 'primitive tourism' in Africa. Highly immunogenic material originating from the intestine of intravascular adult schistosomes gives rise to an antibody response making possible early identification of infected individuals using ser...

journal_title：Parasite immunology

authors： Thors C,Linder E

更新日期：1998-10-01 00:00:00

abstract：:A surface enriched fraction was prepared from adults of Onchocerca volvulus by brief extraction of entire worms with detergent. This was then gel filtered to yield a low molecular weight fraction which functioned specifically in ELISA analysis. An identical result was also obtained when the related cattle parasite, O....

journal_title：Parasite immunology

authors： Cabrera Z,Parkhouse RM

更新日期：1987-01-01 00:00:00

abstract：:To determine the role of T cells and mast cells in intestinal pathology and immune expulsion of intestinal nematodes, worm burdens, goblet cell responses and villus structures were analysed in T- and B-cell-deficient severe combined immunodeficiency (SCID) mice, athymic nu/nu mice and mast cell deficient W/W(v) mice a...

journal_title：Parasite immunology

authors： Hashimoto K,Uchikawa R,Tegoshi T,Takeda K,Yamada M,Arizono N

更新日期：2009-08-01 00:00:00

abstract：:An essential element for continuing transmission of Plasmodium falciparum is the availability of mature gametocytes in human peripheral circulation for uptake by mosquitoes. Natural immune responses to circulating gametocytes may play a role in reducing transmission from humans to mosquitoes. Here, antibody recognitio...

journal_title：Parasite immunology

authors： Dinko B,King E,Targett GA,Sutherland CJ

更新日期：2016-06-01 00:00:00

abstract：:Haemonchus contortus is an economically important parasite that survives the host defense system by modulating the immune response. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is secreted by the parasite and the host responds by producing anti-enzyme antibodies. The enzyme inhibits complement cascade, an arm of t...

journal_title：Parasite immunology

authors： Rajan P,Mishra PKK,Joshi P

更新日期：2019-02-01 00:00:00

abstract：:We describe an ELISA for trophozoite-specific IgA in the intestinal secretions of mice infected with Giardia muris. Using this method, trophozoite-specific IgA was demonstrated in intestinal secretions of Giardia-infected immunocompetent BALB/c mice. Such antibody was undetectable in the intestinal secretions of Giard...

journal_title：Parasite immunology

authors： Heyworth MF,Kung JE,Caplin AB

更新日期：1988-11-01 00:00:00

abstract：:We have previously reported the usefulness of a 26-28 kDa coproantigen of Fasciola hepatica for diagnosis of infection. In this study, the 26-28 kDa coproantigen was biochemically characterized with the aid of monoclonal antibodies (MoAb) in an effort to better understand the biology of the antigen. Differential stain...

journal_title：Parasite immunology

authors： Abdel-Rahman S,O'Reilly KL,Malone JB

更新日期：1999-06-01 00:00:00

abstract：:In the present study we have investigated and compared in vitro the specific complement (C) activating activity of three metacestode preparations of Echinococcus granulosus. Extracts from hydatid cyst fluid (HCF-ext), protoscoleces (PSC-ext) and hydatid cyst membrane (HCM-ext) activated human C producing C3 conversion...

journal_title：Parasite immunology

authors： Irigoín F,Würzner R,Sim RB,Ferreira AM

更新日期：1996-07-01 00:00:00

abstract：:Leishmania mexicana is the causal agent of cutaneous leishmaniasis in Mexico. Dendritic cells (DC) are one of the host cells of Leishmania parasites. Intracellular microorganisms inhibit host cell apoptosis as a strategy to ensure their survival in infected cells. We have previously shown that Leishmania mexicana prom...

journal_title：Parasite immunology

authors： Vázquez-López R,Argueta-Donohué J,Wilkins-Rodríguez A,Escalona-Montaño A,Aguirre-García M,Gutiérrez-Kobeh L

更新日期：2015-11-01 00:00:00

abstract：:The humoral responses of eight cats infected with Brugia pahangi to somatic antigens from all life-cycle stages were examined quantitatively by ELISA and qualitatively by immunoblotting for almost a year post infection. Six cats spontaneously became amicrofilaraemic: their production of IgG antibodies against somatic ...

journal_title：Parasite immunology

authors： Fletcher C,Birch DW,Samad R,Denham DA

更新日期：1986-07-01 00:00:00

abstract：:The life cycle of Taenia solium, the pork tapeworm, is continuously closed in many rural settings in developing countries when free roaming pigs ingest human stools containing T. solium eggs and develop cysticercosis, and humans ingest pork infected with cystic larvae and develop intestinal taeniasis, or may also acci...

journal_title：Parasite immunology

authors： Garcia HH,Rodriguez S,Friedland JS,Cysticercosis Working Group in Peru.

更新日期：2014-08-01 00:00:00

abstract：:A comparison of Plasmodium chabaudi AS infection in BALB/c and BALB/c IgM-deficient mice demonstrated a protective role for IgM during infection. IgM-/- mice, unlike microMT mice, display competent B cell humoral immune responses. Increased susceptibility of IgM-/- mice was demonstrated by increased mortality, an adva...

journal_title：Parasite immunology

authors： Couper KN,Phillips RS,Brombacher F,Alexander J

更新日期：2005-05-01 00:00:00

abstract：:Plasma from chronic or advanced hepatosplenic schistosomiasis (mansoni) patients (PCS) suppressed mitogen-induced responses of normal human peripheral blood mononuclear cells. 1 x 10(5) Ficoll-Hypaque isolated lymphocytes were cultured in 100 microliter RPMI 1640 media with 100 microliter plasma preparation and stimul...

journal_title：Parasite immunology

authors： Kamal KA,Higashi GI

更新日期：1982-07-01 00:00:00

abstract：:Trichuris muris is an intestinal nematode that invades the colonic epithelium triggering a mucosal inflammation. Vitamin A and its active metabolite retinoic acid are strongly linked with the modulation of gut immune responses. Here, we describe the temporal changes in the expression of aldehyde dehydrogenase (ALDH) e...

journal_title：Parasite immunology

authors： Hurst RJ,Else KJ

更新日期：2013-07-01 00:00:00

abstract：:In order to characterize immunodominant components of T. spiralis a workshop was organized. In this the reactivity of monoclonal and polyclonal antibodies, provided by different research groups, towards total extracts from adult, new born larvae and muscle larvae as well as to excretory/secretory components of muscle ...

journal_title：Parasite immunology

authors： Ortega-Pierres MG,Yepez-Mulia L,Homan W,Gamble HR,Lim PL,Takahashi Y,Wassom DI,Appleton JA

更新日期：1996-06-01 00:00:00

abstract：:Male B10 X 129 (10M) ScSn mice were relatively resistant to cutaneous leishmaniasis, while females frequently developed non-healing expanding ulcers, leading to loss of infected extremities, metastasis to distal skin sites, and in some animals, death. Anti-leishmanial antibody titers were higher, and delayed-type hype...

journal_title：Parasite immunology

authors： Giannini MS

更新日期：1986-01-01 00:00:00

abstract：:Net intestinal fluid movement was measured in immunized and non-immunized rats infected with the enteric stages of the nematode, Trichinella spiralis. Animals were studied 30 min, 5 days and 30 days after receiving infective larvae. Net water movement across the mucosal surface of the gut was measured in vivo by perfu...

journal_title：Parasite immunology

authors： Castro GA,Hessel JJ,Whalen G

更新日期：1979-01-01 00:00:00

abstract：:The pathogenesis of the tissue lesions observed in American trypanosomiasis (Chagas' disease) seems to depend on a variety of mechanisms. The present study was dedicated to the investigation of the evolution of muscle lesions and its relationship with immunological and parasitological parameters. Mice were infected i....

journal_title：Parasite immunology

authors： Silva JC,Pirmez C,Morgado MG,Galvão-Castro B

更新日期：1985-09-01 00:00:00