Abstract:
:The efficacy of vaccination against Haemonchus contortus infection with two recombinant proteins, rHco-gal-m and rHco-gal-f, was studied in 9-10-month-old goats. Vaccination with 100 microg protein reduced faecal egg output and worm burdens by 37.25% and 41.1%, respectively. Corresponding reductions with 200 microg protein were 48.03% and 46.19%. Vaccinated groups had significantly higher IgG levels than the negative and positive controls. Significant negative correlations were detected between IgG level, mucosal homogenate IgA concentration, haemoglobin and abomasal worm burden at necropsy. By contrast a positive correlation was found between the percentage of B cells, monocytes and abomasal worm burden. These findings suggested that vaccination with a combination of recombinant rHco-gal-m/f proteins had a role in protecting goats against H. contortus infection.
journal_name
Parasite Immunoljournal_title
Parasite immunologyauthors
Yanming S,Ruofeng Y,Muleke CI,Guangwei Z,Lixin X,Xiangrui Ldoi
10.1111/j.1365-3024.2007.00949.xsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
319-26issue
6eissn
0141-9838issn
1365-3024pii
PIM949journal_volume
29pub_type
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:1985-07-01 00:00:00
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journal_title:Parasite immunology
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journal_title:Parasite immunology
pub_type: 杂志文章
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journal_title:Parasite immunology
pub_type: 杂志文章
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.2006.00926.x
更新日期:2007-03-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:2010-07-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:2014-05-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:1983-03-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:1991-01-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:1983-03-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1046/j.1365-3024.1996.d01-17.x
更新日期:1996-10-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.1981.tb00413.x
更新日期:1981-01-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.1994.tb00299.x
更新日期:1994-01-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.2009.01193.x
更新日期:2010-04-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/pim.12000.x
更新日期:2012-12-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2016-06-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.2009.01197.x
更新日期:2010-06-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.2005.00769.x
更新日期:2005-06-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3024.1979.tb00711.x
更新日期:1979-01-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/pim.12822
更新日期:2021-01-17 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1046/j.1365-3024.2001.00384.x
更新日期:2001-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/pim.12702
更新日期:2020-04-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
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更新日期:1992-07-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1111/pim.12658
更新日期:2019-08-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章
doi:10.1046/j.1365-3024.2002.00476.x
更新日期:2002-07-01 00:00:00
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journal_title:Parasite immunology
pub_type: 杂志文章,评审
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更新日期:2004-11-01 00:00:00