Lipid-altering efficacy of switching to ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk patients with and without metabolic syndrome.

abstract：PURPOSE:Our objectives were to describe recent trends in the characteristics and in-hospital outcomes in diabetic as compared with non-diabetic patients hospitalized with ST-segment elevation myocardial infarction (STEMI). METHODS:We reviewed the medical records of 2537 persons with (n = 684) and without (n = 1853) a ...

journal_title：Diabetes & vascular disease research

authors： Tisminetzky M,Joffe S,McManus DD,Darling C,Gore JM,Yarzebski J,Lessard D,Goldberg RJ

更新日期：2014-05-01 00:00:00

abstract：:We investigated the usefulness of Holter monitoring to detect cardiac disease and predict future cardiovascular risk in asymptomatic diabetic patients. This is a multi-centre, prospective study in 406 asymptomatic diabetic patients. They were categorized into three groups based on findings of Holter monitoring. A tota...

journal_title：Diabetes & vascular disease research

authors： Nakao YM,Ueshima K,Nohara R,Mizunuma Y,Segawa I,Tanaka-Mizuno S,Yasuno S,Nakao K,Hiramori K,Kihara Y

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:C-type lectin receptors, including Dectin-2, are pattern recognition receptors on monocytes and macrophages that mainly recognize sugars and sugar-like structures present on fungi. Activation of C-type lectin receptors induces downstream CARD9 signalling, leading to the production of cytokines. We hypothesiz...

journal_title：Diabetes & vascular disease research

authors： Thiem K,Hoeke G,Zhou E,Hijmans A,Houben T,Boels MG,Mol IM,Lutgens E,Shiri-Sverdlov R,Bussink J,Kanneganti TD,Boon MR,Stienstra R,Tack CJ,Rensen PC,Netea MG,Berbée JF,van Diepen JA

更新日期：2020-01-01 00:00:00

abstract：:Chronic diseases account for approximately 45% of all deaths in developed countries and are particularly prevalent in countries with the most sophisticated and robust public health systems. Chronic metabolic diseases, specifically lifestyle-related diseases pertaining to diet and exercise, continue to be difficult to ...

journal_title：Diabetes & vascular disease research

authors： Ackers I,Malgor R

更新日期：2018-01-01 00:00:00

abstract：:Glucose-lowering treatment options for type 2 diabetes mellitus patients with chronic kidney disease are limited. We evaluated the potential for linagliptin in combination with insulin in type 2 diabetes mellitus patients with mild-to-severe renal impairment. Data for participants in two phase 3 trials with linaglipti...

journal_title：Diabetes & vascular disease research

authors： McGill JB,Yki-Järvinen H,Crowe S,Woerle HJ,von Eynatten M

更新日期：2015-07-01 00:00:00

abstract：:The aim of this study was to evaluate changes in lipid profiles in patients with type 2 diabetes after treatment conversion from rosiglitazone to pioglitazone while maintaining stable statin and other lipid-altering therapies. A total of 305 patients were enrolled in this open-label study. Patients had been taking sta...

journal_title：Diabetes & vascular disease research

authors： Berhanu P,Kipnes MS,Khan MA,Perez AT,Kupfer SF,Spanheimer RC,Demissie S,Fleck PR

更新日期：2006-05-01 00:00:00

abstract：:A cross-sectional analysis of ethnic differences in dietary intake, insulin sensitivity and beta-cell function, using the intravenous glucose tolerance test (IVGTT), was conducted on 497 healthy adult participants of the 'Reading, Imperial, Surrey, Cambridge, and Kings' (RISCK) study. Insulin sensitivity (Si) was sign...

journal_title：Diabetes & vascular disease research

authors： Goff LM,Griffin BA,Lovegrove JA,Sanders TA,Jebb SA,Bluck LJ,Frost GS,RISCK Study Group.

更新日期：2013-07-01 00:00:00

abstract：:While few dispute the existence of the metabolic syndrome as a clustering of factors indicative of poor metabolic health, its utility above that of its individual components in the clinical care of individual patients is questioned. This is likely a consequence of the failure of clinicians and scientists to agree on a...

journal_title：Diabetes & vascular disease research

authors： Nolan CJ,Prentki M

更新日期：2019-03-01 00:00:00

abstract：:Insulin resistance has a broad pathogenic impact affecting metabolic, cardio-renal and other disease areas. Extensive studies to dissect the mechanisms of insulin resistance have provided valuable insights to shape current clinical awareness and advance therapeutic practice. However, the development of direct interven...

journal_title：Diabetes & vascular disease research

authors： Bailey CJ

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Reduced renal function and albuminuria predict cardiovascular (CV) events and mortality in type 2 diabetes (T2D). In addition, we evaluated the role of co-existing congestive heart failure (CHF) and other CV risk factors on CV events in a large observational population-based cohort of T2D patients. RESEARCH ...

journal_title：Diabetes & vascular disease research

authors： Svensson MK,Cederholm J,Eliasson B,Zethelius B,Gudbjörnsdottir S,Swedish National Diabetes Register.

更新日期：2013-11-01 00:00:00

abstract：:Heart failure is now recognized as a progressive disease in which patients transition through the stages of being at risk of heart failure (stage A), to asymptomatic structural heart disease (stage B), to clinical manifestations of heart failure (stage C) and finally end-stage or refractory heart failure (stage D). Th...

journal_title：Diabetes & vascular disease research

authors： Lam CS

更新日期：2015-07-01 00:00:00

abstract：:To assess the prevalence of metabolic syndrome (MS) and estimates of global risk by Framingham Risk Score in young subjects with acute myocardial infarction (MI), we assessed metabolic parameters and global risk assessment in 165 consecutive subjects who presented with myocardial infarction prior to 45 years of age. N...

journal_title：Diabetes & vascular disease research

authors： Zarich S,Luciano C,Hulford J,Abdullah A

更新日期：2006-09-01 00:00:00

abstract：:Insulin resistance typically reflects multiple defects of insulin receptor and post-receptor signalling that impair a diverse range of metabolic and vascular actions. Many potential intervention targets and compounds with therapeutic activity have been described. Proof of principle for a non-peptide insulin mimetic ha...

journal_title：Diabetes & vascular disease research

authors： Bailey CJ

更新日期：2007-03-01 00:00:00

abstract：:Adiponectin circulates in plasma as various isoforms. However, the biological activity of each isoform has not been firmly established. High molecular weight (HMW) adiponectin may be the active form of adiponectin, while a proteolytic cleavage product of adiponectin, known as globular adiponectin (gAd), has recently b...

journal_title：Diabetes & vascular disease research

authors： Tomizawa A,Hattori Y,Kasai K,Nakano Y

更新日期：2008-06-01 00:00:00

abstract：:Peripheral artery disease is a severe complication of diabetes. We have reported that the deletion of angiotensin type 2 receptor in diabetic mice promoted vascular angiogenesis in the ischaemic muscle 4 weeks following ischaemia. However, the angiotensin type 2 receptor deletion beneficial effects occurred 2 weeks po...

journal_title：Diabetes & vascular disease research

authors： Robillard S,Mercier C,Breton V,Paquin-Veillette J,Guay A,Lizotte F,Geraldes P

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes ...

journal_title：Diabetes & vascular disease research

authors： Oliveira AP,Calderon IM,Costa RA,Roscani MG,Magalhães CG,Borges VT

更新日期：2015-05-01 00:00:00

abstract：:Diabetes contributes directly to the development of cardiovascular aortic valve disease. There is currently no drug therapy available for a dysfunctional valve and this urges the need for additional research to identify distinctive mechanisms of cardiovascular aortic valve disease evolution. The aim of this study was ...

journal_title：Diabetes & vascular disease research

authors： Tucureanu MM,Filippi A,Alexandru N,Ana Constantinescu C,Ciortan L,Macarie R,Vadana M,Voicu G,Frunza S,Nistor D,Simionescu A,Simionescu DT,Georgescu A,Manduteanu I

更新日期：2019-11-01 00:00:00

abstract：:Telmisartan partially activates the peroxisome proliferator-activated receptor γ (PPARγ), which may ameliorate the accumulation of visceral adipose tissues and sensitise insulin action. Nineteen patients with essential hypertension and metabolic syndrome were randomly assigned to receive 40 mg of telmisartan (TELMI gr...

journal_title：Diabetes & vascular disease research

authors： Murakami K,Wada J,Ogawa D,Horiguchi CS,Miyoshi T,Sasaki M,Uchida HA,Nakamura Y,Makino H

更新日期：2013-01-01 00:00:00

abstract：:Flow-mediated dilatation evaluation using hand skin heating may possibly be more accurate than post-ischaemic hyperaemia to detect conduit artery endothelial dysfunction in type 1 diabetes. We measured in 24 type 1 diabetic patients (n=16 without microangiopathy) and 24 healthy matched subjects radial artery diameter ...

journal_title：Diabetes & vascular disease research

authors： Bellien J,Costentin A,Dutheil-Maillochaud B,Iacob M,Kuhn JM,Thuillez C,Joannides R

更新日期：2010-04-01 00:00:00

abstract：:Diabetes mellitus and angina pectoris are important conditions in older persons. The utility of pre-diabetes mellitus, diabetes mellitus and other risk factors as predictors of incident angina pectoris among older adults has not been characterized. We examined incident angina pectoris rates by sex and diabetes mellitu...

journal_title：Diabetes & vascular disease research

authors： Mathenge N,Fan W,Wong ND,Hirsch C,Delaney CJ,Amsterdam EA,Koch B,Calara R,Gardin JM

更新日期：2020-01-01 00:00:00

abstract：:Roux-en-Y bypass surgery is increasingly used for treatment of gross obesity due to the general inability of lifestyle change and existing drug treatments to counter the obesity epidemic. This common form of bariatric surgery involves bypass of the small intestine with significant reduction of body of weight that is i...

journal_title：Diabetes & vascular disease research

authors： Flatt PR

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Arterial stiffness has been associated with diabetic retinopathy; however, the information is limited in Asians. We aim to examine the association of central arterial stiffness with the presence and severity of diabetic retinopathy in type 2 diabetes mellitus patients in Singapore. METHODS:Arterial stiffness...

journal_title：Diabetes & vascular disease research

authors： Zhang X,Lim SC,Tavintharan S,Yeoh LY,Sum CF,Ang K,Yeo D,Low S,Kumari N

更新日期：2019-11-01 00:00:00

abstract：:Vascular complications associated with type 2 diabetes confer significant morbidity and mortality. Atherosclerosis develops much earlier and progresses more rapidly than in subjects without diabetes. The clustering of cardiovascular risk factors associated with type 2 diabetes is mainly responsible for accelerated ath...

journal_title：Diabetes & vascular disease research

authors： Steiner G

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The effect of interarm blood pressure difference on the development of diabetic retinopathy, proteinuria and chronic kidney disease remains unknown. We investigated to determine the impact of interarm blood pressure difference on the prevalence of diabetic retinopathy, proteinuria and chronic kidney disease ...

journal_title：Diabetes & vascular disease research

authors： Lee JH,Kim YA,Lee Y,Bang WD,Seo JH

更新日期：2020-07-01 00:00:00

abstract：:We investigated the effect of atorvastatin monotherapy and combined treatment with atorvastatin and pioglitazone on intima-media thickness, vascular function and the cardiovascular risk profile. In all, 148 patients (76 male, 72 female; aged 61.4+/-6.5 years; body mass index [BMI] 29.2+/-4.1 kg/m2; mean +/- SD) with i...

journal_title：Diabetes & vascular disease research

authors： Forst T,Wilhelm B,Pfützner A,Fuchs W,Lehmann U,Schaper F,Weber M,Müller J,Konrad T,Hanefeld M

更新日期：2008-11-01 00:00:00

abstract：:Patients with diabetes mellitus (DM) have accelerated atherosclerosis, which is the main underlying factor contributing to the high risk of atherothrombotic events in these patients. Atherothrombotic complications are the leading cause of morbidity and mortality in patients with DM. Among factors contributing to the p...

journal_title：Diabetes & vascular disease research

authors： Ferreiro JL,Gómez-Hospital JA,Angiolillo DJ

更新日期：2010-10-01 00:00:00

abstract：:Sodium-glucose cotransporter 2 inhibitors are antihyperglycaemic medications with an emerging evidence base for cardiovascular and kidney disease risk reduction. Sodium-glucose cotransporter 2 inhibitors medications lower plasma glucose by inhibiting glucose reabsorption in the proximal tubule of the kidney independen...

journal_title：Diabetes & vascular disease research

authors： de Albuquerque Rocha N,Neeland IJ,McCullough PA,Toto RD,McGuire DK

更新日期：2018-09-01 00:00:00

abstract：:The objective of this study was to evaluate the safety and tolerability of atorvastatin 10 mg compared with placebo in 2,838 patients with type 2 diabetes and no history of coronary heart disease who were enrolled in the Collaborative Atorvastatin Diabetes Study (CARDS) and followed for 3.9 years. The percentages of p...

journal_title：Diabetes & vascular disease research

authors： Newman CB,Szarek M,Colhoun HM,Betteridge DJ,Durrington PN,Hitman GA,Neil HA,Demicco DA,Auster S,Fuller JH,Cards Investigators.

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:We have previously reported insignificant changes in HbA1c after exercise in patients with both type 2 diabetes and coronary artery disease. In this study, we investigated the effect of exercise on endothelial function and possible associations between changes in endothelial function and HbA1c. METHODS:Patie...

journal_title：Diabetes & vascular disease research

authors： Byrkjeland R,Njerve IU,Arnesen H,Seljeflot I,Solheim S

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To characterize copeptin levels and to explore its prognostic importance in patients with acute myocardial infarction with newly detected glucose abnormalities. METHODS:Copeptin was measured in 166 patients with acute myocardial infarction without known diabetes and in 168 age- and gender-matched controls. P...

journal_title：Diabetes & vascular disease research

authors： Smaradottir MI,Ritsinger V,Gyberg V,Norhammar A,Näsman P,Mellbin LG

更新日期：2017-03-01 00:00:00